1. Secondary metabolites from the aerial parts of Centaurea pannonica (Heuff.) Simonk. from Serbia and their chemotaxonomic importance.
- Author
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Milošević Ifantis T, Solujić S, Pavlović-Muratspahić D, and Skaltsa H
- Subjects
- Centaurea classification, Centaurea metabolism, Flavonoids analysis, Flavonoids chemistry, Lactones analysis, Lactones chemistry, Magnetic Resonance Spectroscopy, Molecular Conformation, Molecular Structure, Plant Components, Aerial metabolism, Plant Extracts analysis, Plant Extracts isolation & purification, Serbia, Sesquiterpenes analysis, Sesquiterpenes chemistry, Sesquiterpenes, Germacrane analysis, Sesquiterpenes, Germacrane chemistry, Species Specificity, Centaurea chemistry, Plant Components, Aerial chemistry, Plant Extracts chemistry
- Abstract
The non polar extract of Centaurea pannonica (Heuff.) Simonk., growing wild in Serbia, was studied and twenty-five compounds including 14 sesquiterpene lactones, 7 flavonoids, 3 lignans and 1 phenylpropanoid glycoside were isolated. All compounds were isolated for the first time from this species. Among them, one germacranolide 2α-hydroxy, 8-dehydroxy 15-O-methacrylate salonitenolide (1) and two guaianolides 2α,8α-dihydroxy-dehydrocostus lactone (2) and pannonin (3) are new natural compounds. The structures of the compounds were established on the basis of spectroscopic analyses (UV, IR, HREIMS and 1D & 2D NMR). The chemical profile of C. pannonica, which belongs to the "Centaurea jacea" group, was compared to previously studied taxa of the same group and used to assess the phylogenetic relationships in the group., (Copyright © 2013 Elsevier Ltd. All rights reserved.)
- Published
- 2013
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