1. The effect of hyaluronic acid hydrogels on dental pulp stem cells behavior.
- Author
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Ahmadian E, Eftekhari A, Dizaj SM, Sharifi S, Mokhtarpour M, Nasibova AN, Khalilov R, and Samiei M
- Subjects
- Biocompatible Materials chemistry, Biocompatible Materials pharmacology, Cell Differentiation drug effects, Cell Proliferation drug effects, Dental Pulp ultrastructure, Humans, Hyaluronic Acid chemistry, Hydrogels chemistry, Regenerative Medicine, Stem Cell Transplantation, Stem Cells drug effects, Stem Cells physiology, Tissue Scaffolds, Tooth physiology, Tooth ultrastructure, Dental Caries therapy, Dental Pulp physiology, Hyaluronic Acid pharmacology, Hydrogels pharmacology, Tissue Engineering
- Abstract
Dental caries and trauma, particularly in childhood, are among the most prevalent teeth problems, which result in the creation of cavities and probably tooth loss. Thus, novel regenerative approaches with high efficiency and less toxicity are required. Stem cell therapy along with the implementation of scaffolds has provided excellent opportunities in the regeneration of teeth structure. Hyaluronic acid (HA) hydrogels have enticed great attention in the field of regenerative medicine. The unique chemical and structural properties of HA and its derivatives have enabled their application in tissue engineering. Several factors such as the location and type of the lesion, teeth age, the type of capping materials determine the success rate of pulp therapy. HA hydrogels have been considered as biocompatible and safe scaffold supports in human dental cell therapies., (Copyright © 2019 Elsevier B.V. All rights reserved.)
- Published
- 2019
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