1. No Life Without Death
- Author
-
Marcin Kamiński, Peter H. Krammer, Karsten Gülow, and Michael K. Kießling
- Subjects
Programmed cell death ,Cell ,Regulator ,Cancer ,Biology ,medicine.disease ,medicine.disease_cause ,Bioinformatics ,Autoimmunity ,medicine.anatomical_structure ,Apoptosis ,medicine ,Oxidative stress ,Tissue homeostasis - Abstract
Apoptosis-programed cell death-is the most common form of death in the body. Once apoptosis is induced, proper execution of the cell death program requires the coordinated activation and execution of multiple molecular processes. Here, we describe the pathways and the basic components of the death-inducing machinery. Since apoptosis is a key regulator of tissue homeostasis, an imbalance of apoptosis results in severe diseases like cancer, autoimmunity, and AIDS.
- Published
- 2007
- Full Text
- View/download PDF