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Your search keyword '"Michael Iroezindu"' showing total 2 results
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2 results on '"Michael Iroezindu"'

1. Implications of asymptomatic malaria infections on hematologic parameters in adults living with HIV in malaria-endemic regions with varying transmission intensities

Author

Edwin Kamau, Risper Maisiba, Nicole Dear, Allahna Esber, Ajay P. Parikh, Michael Iroezindu, Emmanuel Bahemana, Hannah Kibuuka, John Owuoth, Jonah Maswai, Benjamin Opot, Raphael O. Okoth, Farid Abdi, Maureen Mwalo, Dennis Juma, Ben Andagalu, Hoseah M. Akala, Neha Shah, Trevor A. Crowell, Jessica Cowden, Christina S. Polyak, and Julie A. Ake

Subjects
HIV, Asymptomatic malaria, Hematologic abnormalities, Kenya, Uganda, Nigeria, Infectious and parasitic diseases, RC109-216
Abstract

Objectives: HIV and malaria coinfection impacts disease management and clinical outcomes. This study investigated hematologic abnormalities in malaria-asymptomatic people living with HIV (PLHIV) in regions with differing malaria transmission. Methods: Study participants were enrolled in the African Cohort Study: two sites in Kenya, one in Uganda, and one in Nigeria. Data was collected at enrollment and every 6 months. Logistic regression estimated odds ratios for associations between HIV/malaria status and anemia, thrombocytopenia, and leucopenia. Results: Samples from 1587 participants with one or more visits comprising 1471 (92.7%) from PLHIV and 116 (7.3%) without HIV were analyzed. Parasite point prevalence significantly differed across the study sites (P

Published
2023
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2. Contributions of pulmonary hypertension to HIV-related cardiac dysfunction

Author

Godsent Isiguzo, Augustine N. Odili, Basil N. Okeahialam, Ugoagwu Placid, SS Danbauchi, and Michael Iroezindu

Subjects
Adult, Male, medicine.medical_specialty, RD1-811, Hypertension, Pulmonary, Human immunodeficiency virus (HIV), HIV Infections, Comorbidity, medicine.disease_cause, Risk Assessment, Severity of Illness Index, Cardiac dysfunction, Pulmonary hypertension, Ventricular Dysfunction, Left, Young Adult, Age Distribution, Acquired immunodeficiency syndrome (AIDS), Reference Values, Internal medicine, Prevalence, Medicine, Diseases of the circulatory (Cardiovascular) system, Humans, Sex Distribution, Letter to the Editor, Heart Failure, Diastolic, business.industry, HIV, Stroke Volume, Middle Aged, medicine.disease, Survival Analysis, Echocardiography, Doppler, Cross-Sectional Studies, RC666-701, Cardiology, Disease Progression, Surgery, Female, business, Cardiology and Cardiovascular Medicine, Follow-Up Studies, Heart Failure, Systolic
Abstract

Background/Aim: To evaluate the prevalence of pulmonary hypertension among patients living with HIV/AIDS and to determine its contribution to cardiac dysfunction. Method: A hospital based cross sectional study was carried out over a 6-month period at the Jos University Teaching Hospital. The subjects were 200 confirmed HIV positive patients, ≥18 years of age who consented to the study. Physical examination, laboratory investigations, 2 dimensional and Doppler echocardiography were conducted on the subjects. Results: The mean age of the patients was 38 ± 9 years, and there were 142 females (71%). Females were younger, mean age 36 ± 8 years versus 41 ± 10 years for males (p-value

Published
2013

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