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Background: Breast cancer is the most common malignant tumor among women, and its incidence is increasing annually. At present, the results of the study on whether optical coherence tomography (OCT) can be used as an intraoperative margin assessment method for breast-conserving surgery (BCS) are inconsistent. We herein conducted this systematic review and meta-analysis to assess the diagnostic value of OCT in BCS., Methods: PubMed, Web of Science, Cochrane Library, and Embase were used to search relevant studies published up to September 15, 2022. We used Review Manager 5.4, Meta-Disc 1.4, and STATA 16.0 for statistical analysis., Results: The results displayed 18 studies with 782 patients included according to the inclusion and exclusion criteria. Meta-analysis showed the pooled sensitivity, specificity, positive likelihood ratio (PLR), negative likelihood ratio (NLR), diagnostic odds ratio (DOR) and the area under the curve (AUC) of OCT in the margin assessment of BCS were 0.91 (95% CI 0.88-0.93), 0.88 (95% CI 0.83-0.92), 7.53 (95% CI 5.19-10.93), 0.11(95% CI 0.08-0.14), 70.37 (95% CI 39.78-124.47), and 0.94 (95% CI 0.92-0.96), respectively., Conclusions: OCT is a promising technique in intraoperative margin assessment of breast cancer patients., Competing Interests: Declaration of Competing Interest None., (Copyright © 2023. Published by Elsevier B.V.)

Polycyclic aromatic hydrocarbons (PAHs) have toxic, teratogenic, mutagenic and carcinogenic effects on living organisms. Plants can function as pollutant bioindicators and bioaccumulators due to their wide surface distribution and specific responses to atmospheric pollutants. However, various plants exhibit significant differences in their capacities to accumulate PAHs. At present, research has mainly focused on the effects of leaf morphology and physiological characteristics, and few studies have evaluated the effects of the leaf surface on PAH accumulation. We aimed to assess the factors impacting the uptake and accumulation of PAHs by leaves. We selected 8 common tree species in Shanghai, China, and used supercritical fluid extraction technology to determine the content of PAHs in their leaves. Specific measurements of leaf area, width/length, wax content, and stomatal density were applied to index the morphological and physiological characteristics; surface roughness, surface free energy, polar components, and dispersion components were compiled into an adsorption performance index. Principal component analysis (PCA) and canonical correlation analysis (CCA) were used to assess the effects of different leaf characteristics on PAH accumulation. We found that the mean concentrations of ΣPAHs ranged from 300 to 2000 ng·g -1 and that the proportions of different benzene rings were significantly different among the different tree species. Leaf morphology and physiological characteristics had more significant effects compared to surface adsorption. CCA showed a significant negative correlation between leaf morphological characteristics and wax content, but had no significant correlation with surface adsorption. Low-molecular-weight PAHs were found to be mainly affected by the morphological characteristics, while medium- and high-molecular-weight PAHs were influenced by wax content and adsorption. Our conclusions provide a theoretical basis for the establishment of a reliable plant atmosphere-monitoring system and a method for screening tree species with strong PAH adsorption capacity., (Copyright © 2018 Elsevier B.V. All rights reserved.)