1. Herpes simplex virus-2 associated with a large fungating penile mass
- Author
-
Benjamin N. Breyer, Max Bowman, Gregory Amend, Kieron S. Leslie, and Ursula E. Lang
- Subjects
Urologic Diseases ,Pathology ,medicine.medical_specialty ,Urology ,viruses ,030232 urology & nephrology ,Human immunodeficiency virus (HIV) ,medicine.disease_cause ,lcsh:RC870-923 ,Lesion ,03 medical and health sciences ,chemistry.chemical_compound ,0302 clinical medicine ,medicine ,Infectious disease ,business.industry ,Genital lesion ,Inflammation and Infection ,HIV ,Histology ,Herpes ,lcsh:Diseases of the genitourinary system. Urology ,Reconstructive urology ,Infectious Diseases ,medicine.anatomical_structure ,Herpes simplex virus ,chemistry ,Nodular lesions ,030220 oncology & carcinogenesis ,HIV/AIDS ,Sexually Transmitted Infections ,medicine.symptom ,Infection ,Penile mass ,business ,Penis ,Cidofovir - Abstract
A 48-year-old male with HIV/AIDS presented with an enlarging nodular lesion on the base of his penis. Histology revealed changes consistent with chronic viral infection and culture grew herpes simplex virus 2 (HSV-2). The lesion was refractory to valacyclovir and intralesional (IL) cidofovir therapy. Urology excised the mass and the defect was repaired primarily with good cosmetic result. Post-operative pathology confirmed HSV-2 despite the unusual appearance of the lesion consisting of nodular mass without gross ulceration.
- Published
- 2021