1. Acute Atraumatic Compartment Syndrome of the Hand Due to Acquired Hemophilia A
- Author
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Daniel Walder, MD, Thuan Ly, MD, Claudia Meuli-Simmen, MD, Mario Bargetzi, MD, and Flavien Mauler, MD
- Subjects
Surgery ,RD1-811 - Abstract
Acquired hemophilia A (factor VIII inhibitor) is a rare idiopathic disease with a high rate of morbidity and mortality. We report the case of an 83-year-old woman who presented with atraumatic compartment syndrome of the right hand resulting from spontaneous bleeding. Urgent fasciotomy was performed. Only after several revision surgeries and a complicated course could the resulting defects be closed by secondary intention and skin grafting. The patient needed interdisciplinary care involving early initiation of clotting factor replacement and immunosuppressive therapy to control the bleeding. Acquired hemophilia A must be considered as an important life-threating differential diagnosis in cases of atraumatic compartment syndrome. Primary treatment differs from the traumatic compartment syndrome. Early diagnosis with immediate start of replacement therapy to correct coagulation and initialization of immunosuppressive therapy are crucial for successful treatment. Key words: acquired hemophilia A, compartment syndrome of the hand, factor VIII inhibitor, fasciotomy
- Published
- 2019
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