Author: "Marchese E." / Publisher: elsevier - Searchworks@Jio Institute Digital Library Search Results

36 results on '"Marchese E."'

1. Galea-pericranium dural closure: Can we safely avoid sealants?

Author: Giovanni, S., Della Pepa, G. M., La Rocca, G., Lofrese, G., Albanese, A., Maria, G., Marchese, E., Della Pepa G. M. (ORCID:0000-0001-8698-3359), Albanese A. (ORCID:0000-0001-8783-2974), Marchese E. (ORCID:0000-0001-8551-0357), Giovanni, S., Della Pepa, G. M., La Rocca, G., Lofrese, G., Albanese, A., Maria, G., Marchese, E., Della Pepa G. M. (ORCID:0000-0001-8698-3359), Albanese A. (ORCID:0000-0001-8783-2974), and Marchese E. (ORCID:0000-0001-8551-0357)
Abstract: Objective Dural closure is one of the most critical steps in neurosurgical procedures as it prevents many common postoperative complications. Methods of dural closure include the use of allogenic, autogenic, xenogenic, absorbable or synthetic materials together with sealant/glues or hemostatic compounds. Most common autogenic graft is galea-pericranium. This study aims to demonstrate how the intrinsic properties of the galea-pericranium make effectively useless the application of any glue in order to ensure the watertight integrity of the graft. Patients and methods 276 cases were included in the study. Postoperative dural-closure related complication in patients subjected to duraplasty were analysed in three groups undergoing different duraplasty techniques: galea-pericranium graft without sealants, galea-pericranium graft plus sealant, non-autologous dural patch plus sealant. Results No statistically significant differences between the three groups were observed in terms of subcutaneous fluid collection rate, CSF fistulas, brain abscesses, subdural empyemas, wound dehiscence, radiotherapic sequelae. Conclusions Our study shows that galea-pericranium alone (without sealants) is comparable to other duraplasty techniques that involve the use of sealants or of non-autologous pathches in terms of long term postoperative results. © 2014 Elsevier B.V.
Published: 2014

2. Search for heavy long-lived charged particles with the ATLAS detector in pp collisions at root s=7 TeV

Author: Aad, G[ 71 ], Abbott, B[ 150 ], Abdallah, J[, 16, 18, ], Abdelalim, AA[ 72 ], Abdesselam, A[ 158 ], Abdinov, O[ 15 ], Abi, B[ 151 ], Abolins, M[ 124 ], Abramowicz, H[ 208 ], Abreu, 154, H[, 155, ], Acerbi, 125, E[, 126, ], Acharya, Bs[, 221, 222, ], Adams, DL[ 38 ], Addy, TN[ 84 ], Adelman, J[ 238 ], Aderholz, M[ 136 ], Adomeit, S[ 135 ], Adragna, P[ 108 ], Adye, T[ 173 ], Aefsky, S[ 35 ], Aguilar, Saavedra, Ja[, 167, 168, ], Aharrouche, M[ 116 ], Ahlen, SP[ 34 ], Ahles, F[ 71 ], Ahmad, A[ 203 ], Ahsan, M[ 63 ], Aielli, G[ 178 ], Akdogan, T[ 27 ], Akesson, TPA[ 114 ], Akimoto, G[, 81, 210, 211, ], Akimov, AV[ 131 ], Akiyama, A[ 97 ], Alam, MS[ 2 ], Alam, MA[ 109 ], Albrand, S[, 81, 83, ], Aleksa, M[ 45 ], Aleksandrov, IN[ 95 ], Alessandria, F[ 125 ], Alexa, C[ 39 ], Alexander, G[ 208 ], Alexandre, G[ 72 ], Alexopoulos, T[ 14 ], Alhroob, M[ 33 ], Aliev, M[ 23 ], Alimonti, G[ 125 ], Alison, J[ 161 ], Aliyev, M[ 15 ], Allport, PP[ 105 ], Allwood Spiers, SE[ 79 ], Almond, J[ 117 ], Aloisio, A[, 36, 139, 140, ], Alon, R[ 172 ], Alonso, A[ 114 ], Alviggi, Mg[, 139, Amako, K[ 96 ], Amaral, P[ 45 ], Amelung, C[ 35 ], Ammosov, VV[ 172 ], Amorim, 166, A[, 241, 242, ], Amoros, 226, G[, 227, 228, 229, 230, ], Amram, N[ 208 ], Anastopoulos, C[ 45 ], Andari, 154, N[, Andeen, T[ 56 ], Anders, CF[ 33 ], Anderson, KJ[ 46 ], Andreazza, 125, A[, Andrei, V[ 86 ], Andrieux, Ml[, 81, Anduaga, Xs[, 100, 101, ], Angerami, A[ 56 ], Anghinolfi, F[ 45 ], Anjos, N[ 166 ], Annovi, A[ 70 ], Antonaki, A[ 13 ], Antonelli, M[ 70 ], Antonov, A[ 133 ], Antos, J[ 197 ], Anulli, F[ 176 ], Aoun, 118, S[, 119, ], Bella, La[, 9, 10, ], Apolle, 158, R[, 243, ], Arabidze, G[ 124 ], Aracena, I[ 195 ], Arai, Y[ 96 ], Arce, ATH[ 68 ], Archambault, JP[ 44 ], Arfaoui, S[ 45 ], Arguin, JF[ 22 ], Arik, E[ 27 ], Arik, M[ 27 ], Armbruster, AJ[ 123 ], Arnaez, O[ 116 ], Arnault, 154, C[, Artamonov, A[ 132 ], Artoni, 176, G[, 177, 179, ], Arutinov, D[ 33 ], Asai, Asfandiyarov, R[ 235 ], Ask, S[ 43 ], Asman, 200, B[, 201, ], Asquith, L[ 1 ], Assamagan, K[ 38 ], Astbury, A[ 232 ], Astvatsatourov, A[ 78 ], Atoian, G[ 238 ], Aubert, B[, 9, Auerbach, B[ 238 ], Auge, 154, E[, Augsten, K[ 171 ], Aurousseau, M[ 198 ], Austin, N[ 105 ], Avramidou, R[ 14 ], Axen, D[ 231 ], C[ 80 ], Ay, Azuelos, G[ 130 ], Azuma, Y[, 81, Baak, MA[ 45 ], Baccaglioni, G[ 125 ], Bacci, 180, C[, 181, ], Bach, AM[ 22 ], Bachacou, H[ 188 ], Bachas, K[ 45 ], Bachy, G[ 45 ], Backes, M[ 72 ], Backhaus, M[ 33 ], Badescu, E[ 39 ], Bagnaia, 176, P[, Bahinipati, S[ 3 ], Bai, Y[ 49 ], Bailey, DC[ 214 ], Bain, T[ 214 ], Baines, JT[ 173 ], Baker, OK[ 238 ], Baker, MD[ 38 ], Baker, S[ 110 ], Pedrosa, FBD[ 45 ], Banas, E[ 61 ], Banerjee, P[ 130 ], Banerjee, S[ 235 ], Banfi, D[ 45 ], Bangert, A[ 189 ], Bansal, V[ 232 ], Bansil, HS[ 26 ], Barak, L[ 234 ], Baranov, SP[ 131 ], Barashkou, A[ 95 ], Galtieri, AB[ 22 ], Barber, T[ 43 ], Barberio, EL[ 122 ], Barberis, D[, 73, 74, ], Barbero, M[ 33 ], Bardin, DY[ 95 ], Barillari, T[ 136 ], Barisonzi, M[ 237 ], Barklow, T, Barlow, N[ 43 ], Barnett, BM[ 173 ], Barnett, RM[ 22 ], Baroncelli, A[ 180 ], Barr, AJ[ 158 ], Barreiro, F[ 115 ], da Costa, JBG[ 85 ], Barrillon, 154, R[, Bartoldus, R, Barton, AE[ 102 ], Bartsch, D[ 33 ], Bartsch, V[ 204 ], Bates, RL[ 79 ], Batkova, L[ 196 ], Batley, JR[ 43 ], Battaglia, A[, 24, 25, ], Battistin, M[ 45 ], Battistoni, G[ 125 ], Bauer, F[ 188 ], Bawa, HS[ 195 ], Beare, B[ 214 ], Beau, 111, T[, 112, 113, ], Beauchemin, PH[ 158 ], Beccherle, R[ 74 ], Bechtle, P[, 64, 65, ], Beck, Hp[, 24, Beckingham, M[ 71 ], Becks, KH[ 237 ], Beddall, AJ[ 29 ], Beddall, A[ 29 ], Bedikian, S[ 238 ], Bednyakov, VA[ 95 ], Bee, Cp[, 118, Begel, M[ 38 ], Harpaz, SB[ 207 ], Behera, PK[ 93 ], Beimforde, M[ 136 ], Belanger Champagne, C[ 225 ], Bell, PJ[ 72 ], Bell, WH[ 72 ], Bella, G[ 208 ], Bellagambala, L[ 32 ], Bellina, F[ 45 ], Bellomo, M[ 159 ], Belloni, A[ 85 ], Beloborodova, O[ 146 ], Belotskiy, K[ 133 ], Beltramello, O[ 45 ], Ben Ami, S[ 207 ], Benary, O[ 208 ], Benchekroun, D[ 182 ], Benchouk, 118, C[, Bendel, M[ 116 ], Benedict, BH[ 220 ], Benekos, N[ 224 ], Benhammou, Y[ 208 ], Benjamin, DP[ 68 ], Benoit, 154, M[, Bensinger, JR[ 35 ], Benslama, K[ 174 ], Bentvelsen, 143, S[, 144, ], Berge, D[ 45 ], Kuutmann, Eb[, 64, Berger, N[, 9, Berghaus, F[ 232 ], Berglund, E[ 72 ], Beringer, J[ 22 ], Bernardet, 118, K[, Bernat, P[ 110 ], Bernhard, R[ 71 ], Bernius, C[ 38 ], Berry, T[ 109 ], Bertin, A[, 31, 32, ], Bertinelli, F[ 45 ], Bertolucci, 163, F[, 164, ], Besana, Mi[, 125, Besson, N[ 188 ], Bethke, S[ 136 ], Bhimji, W[ 69 ], Bianchi, RM[ 45 ], Bianco, 103, M[, 104, ], Biebel, O[ 135 ], Bieniek, SP[ 110 ], Biesiada, J[ 22 ], Biglietti, 180, M[, Bilokon, H[ 70 ], Bindi, M[, 31, Binet, 154, S[, Bingul, A[ 29 ], Bini, 176, C[, Biscarat, C[ 240 ], Bitenc, U[ 71 ], Black, KM[ 34 ], Blair, RE[ 1 ], Blanchard, Jb[, 154, Blanchot, G[ 45 ], Blazek, T[ 196 ], Blocker, C[ 35 ], Blocki, J[ 61 ], Blondel, A[ 72 ], Blum, W[ 116 ], Blumenschein, U[ 80 ], Bobbink, Gj[, 143, Bobrovnikov, VB[ 146 ], Bocchetta, SS[ 114 ], Bocci, A[ 68 ], Boddy, CR[ 158 ], Boehler, M[, 64, Boek, J[ 237 ], Boelaert, N[ 57 ], Boser, S[ 110 ], Bogaerts, JA[ 45 ], Bogdanchikov, A[ 146 ], Bogouch, A[ 127 ], Bohm, C[ 200 ], Boisvert, V[ 109 ], Bold, T[ 220 ], Boldea, V[ 39 ], Bolnet, NM[ 188 ], Bona, M[ 108 ], Bondarenko, VG[ 133 ], Boonekamp, M[ 188 ], Boorman, G[ 109 ], Booth, CN[ 191 ], Bordoni, 111, S[, Borer, C[, 24, Borisov, A[ 172 ], Borissov, G[ 102 ], Borjanovic, I[ 19 ], Borroni, 176, S[, Bos, 143, K[, Boscherini, D[ 32 ], Bosman, M[, 16, Boterenbrood, 143, H[, Botterill, D[ 173 ], Bouchami, J[ 130 ], Boudreau, J[ 165 ], Bouhova Thacker, EV[ 102 ], Boulahouache, C[ 165 ], Bourdarios, Bousson, 118, N[, Boveia, A[ 46 ], Boyd, J[ 45 ], Boyko, IR[ 95 ], Bozhko, NI[ 172 ], Bozovic Jelisavcic, I[ 20 ], Bracinik, J[ 26 ], Braem, A[ 45 ], Branchini, P[ 180 ], Brandenburg, GW[ 85 ], Brandt, A[ 12 ], Brandt, G[ 23 ], Brandt, O[ 80 ], Bratzler, U[ 212 ], Brau, B[ 120 ], Brau, JE[ 153 ], Braun, HM[ 237 ], Brelier, B[ 214 ], Bremer, J[ 45 ], Brenner, R[ 225 ], Bressler, S[ 207 ], Breton, 154, D[, Britton, D[ 79 ], Brochu, FM[ 43 ], Brock, I[ 124 ], Brock, R[ 102 ], Brodbeck, TJ[ 208 ], Brodet, E[ 125 ], Broggi, F[ 124 ], Bromberg, C[ 124 ], Brooijmans, G[ 56 ], Brooks, WK[ 48 ], Brown, G[ 117 ], Brown, H[ 12 ], de Renstrom, PAB[ 61 ], Bruncko, D[ 197 ], Bruneliere, R[ 71 ], Brunet, S[ 91 ], Bruni, A[ 32 ], Bruni, G[ 32 ], Bruschi, M[ 32 ], Buanes, T[ 21 ], Bucci, F[ 72 ], Buchanan, J[ 158 ], Buchanan, NJ[ 3 ], Buchholz, P[ 193 ], Buckingham, RM[ 158 ], Buckley, AG[ 69 ], Buda, SI[ 39 ], Budagov, IA[ 95 ], Budick, B[ 147 ], Buscher, V[ 116 ], Bugge, L[ 157 ], Buira Clark, D[ 158 ], Bulekov, O[ 133 ], Bunse, M[ 66 ], Buran, T[ 157 ], Burckhart, H[ 45 ], Burdin, S[ 105 ], Burgess, T[ 21 ], Burke, S[ 173 ], Busato, E[, 53, 55, ], Bussey, P[ 79 ], Buszello, CP[ 225 ], Butin, F[ 45 ], Butler, B[ 195 ], Butler, JM[ 34 ], Buttar, CM[ 79 ], Butterworth, JM[ 110 ], Buttinger, W[ 43 ], Byatt, T[ 110 ], Urban, Sc[, 226, 230, 229, ], Caforio, D[, 31, Cakir, O[ 4 ], Calafiura, P[ 22 ], Calderini, 111, G[, Calfayan, P[ 135 ], Calkins, R[ 145 ], Caloba, LP[ 36 ], Caloi, 176, R[, Calvet, D[, 53, S[, 53, Toro, Rc[, 53, Camarri, P[ 178 ], Cambiaghi, 159, M[, 160, ], Cameron, D[ 157 ], Campana, S[ 45 ], Campanelli, M[ 110 ], Canale, 139, V[, Canelli, F[ 46 ], Canepa, A[ 216 ], Cantero, J[ 115 ], Capasso, 139, L[, Garrido, MDMC[ 45 ], Caprini, I[ 39 ], Caprini, M[ 39 ], Capriotti, D[ 136 ], Capua, M[, 58, 59, ], Caputo, R[ 203 ], Caramarcu, C[ 39 ], Cardarelli, R[ 178 ], Carli, T[ 45 ], Carlino, G[ 139 ], Carminati, 125, L[, Caron, B[ 216 ], Caron, S[ 71 ], Montoya, GDC[ 235 ], Carter, AA[ 108 ], Carter, JR[ 43 ], Carvalho, J[ 166 ], Casadei, D[ 147 ], Casado, Mp[, 16, Cascella, 163, M[, Caso, C[, 73, Hernandez, AMC[ 235 ], Castaneda Miranda, E[ 235 ], Gimenez, Vc[, 226, Castro, NF[ 166 ], Cataldi, G[ 103 ], Cataneo, F[ 45 ], Catinaccio, A[ 45 ], Catmore, JR[ 102 ], Cattai, A[ 45 ], Cattani, G[ 178 ], Caughron, S[ 124 ], Cauz, Diego, Cavalleri, 111, P[, Cavalli, D[ 125 ], Cavalli, Sforza, Cavasinni, 163, V[, Ceradini, 180, F[, Chakraborty, D[ 145 ], Chan, K[ 3 ], Chapleau, B[ 121 ], Chapman, JD[ 43 ], Chapman, JW[ 123 ], Chareyre, 111, E[, Charlton, DG[ 26 ], Chavda, V[ 117 ], Barajas, CAC[ 45 ], Cheatham, S[ 121 ], Chekanov, S[ 1 ], Chekulaev, SV[ 216 ], Chelkov, GA[ 95 ], Chelstowska, MA[ 142 ], Chen, C[ 94 ], Chen, H[ 38 ], Chen, S[ 51 ], Chen, T[ 51 ], Chen, X[ 235 ], Cheng, S[ 49 ], Cheplakov, A[ 95 ], Chepurnov, VF[ 95 ], El Moursli, RC[ 187 ], Chernyatin, V[ 38 ], Cheu, E[ 11 ], Cheung, SL[ 214 ], Chevalier, L[ 188 ], Chiefari, 139, G[, Chikovani, L[, 75, 77, ], Childers, JT[ 86 ], Chilingarov, A[ 102 ], Chiodini, G[ 103 ], Chizhov, MV[ 95 ], Choudalakis, G[ 46 ], Chouridou, S[ 189 ], Christidi, IA[ 110 ], Christov, A[ 71 ], Chromek Burckhart, D[ 45 ], Chu, ML[ 206 ], Chudoba, J[ 169 ], Ciapetti, Ciba, K[ 60 ], Ciftci, AK[ 4 ], Ciftci, R[ 4 ], Cinca, Cindro, 106, V[, 107, ], Ciobotaru, MD[ 220 ], Ciocca, C[, 31, Ciocio, A[ 22 ], Cirilli, M[ 123 ], Ciubancan, M[ 39 ], Clark, A[ 72 ], Clark, PJ[ 69 ], Cleland, W[ 165 ], Clemens, Jc[, 118, Clement, B[, 81, 200, C[, Clifft, RW[ 173 ], Coadou, 118, Y[, Cobal, Marina, Coccaro, A[, 73, Cochran, J[ 94 ], Coe, P[ 158 ], Cogan, JG[ 195 ], Coggeshall, J[, 32, 224, ], Cogneras, E[ 240 ], Cojocaru, CD[ 44 ], Colas, J[, 9, Colijn, Ap[, 143, Collard, Collins, NJ[ 26 ], Collins Tooth, C[ 79 ], Collot, J[, 81, Colon, G[ 120 ], Muino, PC[ 166 ], Coniavitis, E[ 158 ], Conidi, Mc[, 16, Consonni, M[ 142 ], Consorti, V[ 71 ], Constantinescu, S[ 39 ], Conta, 159, C[, Conventi, F[ 139 ], Cook, J[ 45 ], Cooke, M[ 22 ], Cooper, BD[ 110 ], Cooper Sarkar, AM[ 158 ], Cooper Smith, NJ[ 109 ], Copic, K[ 56 ], Cornelissen, T[, 73, Corradi, M[ 32 ], Corriveau, F[ 121 ], Cortes Gonzalez, A[ 224 ], Cortiana, G[ 136 ], Costa, G[ 125 ], Costa, Mj[, 226, Costanzo, D[ 191 ], Costin, T[ 46 ], Cote, D[ 45 ], Torres, RC[ 36 ], Courneyea, L[ 232 ], Cowan, G[ 109 ], Cowden, C[ 43 ], Cox, BE[ 117 ], Cranmer, K[ 147 ], Crescioli, Cristinziani, M[ 33 ], Crosetti, G[, 58, Crupi, 103, R[, Crepe, Renaudin, Cuciuc, CM[ 39 ], Almenar, CC[ 238 ], Donszelmann, TC[ 191 ], Cuneo, S[, 73, Curatolo, M[ 70 ], Curtis, CJ[ 26 ], Cwetanski, P[ 91 ], Czirr, H[ 193 ], Czyczula, Z[ 157 ], D'Auria, S[ 79 ], D'Onofrio, M[ 105 ], D'Orazio, 176, A[, Da Silva, PVM[ 36 ], Da Via, C[ 117 ], Dabrowski, W[ 60 ], Dai, T[ 123 ], Dallapiccola, C[ 120 ], Dam, M[ 57 ], Dameri, M[ 73 ], Damiani, DS[ 189 ], Danielsson, HO[ 45 ], Dannheim, D[ 136 ], Dao, V[ 72 ], Darbo, G[ 74 ], Darlea, Gl[, 39, 40, ], Daum, 143, C[, Dauvergne, JP[ 45 ], Davey, W[ 122 ], Davidek, T[ 170 ], Davidson, N[ 122 ], Davidson, R[ 102 ], Davies, 158, E[, Davies, M[ 130 ], Davison, AR[ 110 ], Davygora, Y[ 86 ], Dawe, E[ 194 ], Dawson, I[ 191 ], Dawson, JW[ 1 ], Daya, RK[ 62 ], K[ 12 ], De, de Asmundis, R[ 139 ], Castro, De, S[, 31, Salgado, PEDF[ 38 ], Cecco, De, de Graat, J[ 135 ], De Groot, N[ 142 ], Jong, De, 143, P[, De la Taille, De la Torre, H[ 115 ], DE LOTTO, Barbara, De Mora, L[ 102 ], Nooij, De, 143, L[, Branco, MD[ 45 ], De Pedis, D[ 176 ], Saintignon, De, P[, 81, De Salvo, A[ 176 ], Sanctis, De, 221, U[, 223, ], De Santo, A[ 204 ], Regie, De, Jbd[, 154, Dean, S[ 110 ], Dedovich, DV[ 95 ], Degenhardt, J[ 161 ], Dehchar, M[ 158 ], Deile, M[ 135 ], Del, Papa, 221, C[, Del Peso, JJ[ 115 ], Del, Prete, 163, T[, Deliyergiyev, 106, M[, Dell'Acqua, A[ 45 ], Dell'Asta, Della Pietra, M[ 139 ], Della, Volpe, 139, D[, Delmastro, M[ 45 ], Delpierre, 118, P[, Delruelle, N[ 45 ], Delsart, Pa[, 81, Deluca, C[ 203 ], Demers, S[ 238 ], Demichev, M[ 95 ], Demirkoz, B[, 16, 18, 17, 244, ], Deng, J[ 220 ], Denisov, SP[ 172 ], Derendarz, D[ 61 ], Derkaoui, Je[, 185, 186, ], Derue, 111, F[, Dervan, P[ 105 ], Desch, K[ 33 ], Devetak, E[ 203 ], Deviveiros, PO[ 214 ], Dewhurst, A[, 45, 173, ], Dewilde, B[ 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135 ], Zhuravlov, V[ 136 ], Zieminska, D[ 91 ], Zimmermann, R[ 33 ], Zimmermann, S[ 33 ], Zimmermann, S[ 71 ], Ziolkowski, M[ 193 ], Zitoun, Zivkovic, L[ 56 ], Zmouchko, VV[ 172 ], Zobernig, G[ 235 ], Zoccoli, Zolnierowski, Y[, 9, Zsenei, A[ 45 ], zur Nedden, M[ 23 ], Zutshi, V[ 145 ], Zwalinski, (Zwalinski, L., ATLAS (IHEF, IoP, FNWI), G., Aad, Bianco, Michele, G., Chiodini, Gorini, Edoardo, Primavera, Margherita, Spagnolo, Stefania Antonia, Ventura, Andrea, Laboratoire de Physique Subatomique et de Cosmologie (LPSC), Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Institut Polytechnique de Grenoble - Grenoble Institute of Technology-Centre National de la Recherche Scientifique (CNRS), Centre de Calcul de l'IN2P3 (CC-IN2P3), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Laboratoire de Physique Corpusculaire - Clermont-Ferrand (LPC), Université Blaise Pascal - Clermont-Ferrand 2 (UBP)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique Corpusculaire, Université Blaise Pascal - Clermont-Ferrand 2 (UBP)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université Blaise Pascal - Clermont-Ferrand 2 (UBP)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Centre de Physique des Particules de Marseille (CPPM), Aix Marseille Université (AMU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), APC - Neutrinos, Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de l'Accélérateur Linéaire (LAL), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'Annecy de Physique des Particules (LAPP), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS), ATLAS, Aad, G, Abbott, B, Abdallah, J, Abdelalim, Aa, Abdesselam, A, Abdinov, O, Abi, B, Abolins, M, Abramowicz, H, Abreu, H, Acerbi, E, Acharya, B, Adams, Dl, Addy, Tn, Adelman, J, Aderholz, M, Adomeit, S, Adragna, P, Adye, T, Aefsky, S, Aguilar Saavedra, Ja, Aharrouche, M, Ahlen, Sp, Ahles, F, Ahmad, A, Ahsan, M, Aielli, G, Akdogan, T, Akesson, Tpa, Akimoto, G, Akimov, Av, Akiyama, A, Alam, M, Alam, Ma, Albrand, S, Aleksa, M, Aleksandrov, In, Alessandria, F, Alexa, C, Alexander, G, Alexandre, G, Alexopoulos, T, Alhroob, M, Aliev, M, Alimonti, G, Alison, J, Aliyev, M, Allport, Pp, Allwood Spiers, Se, Almond, J, Aloisio, A, Alon, R, Alonso, A, Alviggi, Mg, Amako, K, Amaral, P, Amelung, C, Ammosov, Vv, Amorim, A, Amoros, G, Amram, N, Anastopoulos, C, Andari, N, Andeen, T, Anders, Cf, Anderson, Kj, Andreazza, A, Andrei, V, Andrieux, Ml, Anduaga, X, Angerami, A, Anghinolfi, F, Anjos, N, Annovi, A, Antonaki, A, Antonelli, M, Antonov, A, Antos, J, Anulli, F, Aoun, S, Bella, La, Apolle, R, Arabidze, G, Aracena, I, Arai, Y, Arce, Ath, Archambault, Jp, Arfaoui, S, Arguin, Jf, Arik, E, Arik, M, Armbruster, Aj, Arnaez, O, Arnault, C, Artamonov, A, Artoni, G, Arutinov, D, Asai, S, Asfandiyarov, R, Ask, S, Asman, B, Asquith, L, Assamagan, K, Astbury, A, Astvatsatourov, A, Atoian, G, Aubert, B, Auerbach, B, Auge, E, Augsten, K, Aurousseau, M, Austin, N, Avramidou, R, Axen, D, Ay, C, Azuelos, G, Azuma, Y, Baak, Ma, Baccaglioni, G, Bacci, C, Bach, Am, Bachacou, H, Bachas, K, Bachy, G, Backes, M, Backhaus, M, Badescu, E, Bagnaia, P, Bahinipati, S, Bai, Y, Bailey, Dc, Bain, T, Baines, Jt, Baker, Ok, Baker, Md, Baker, S, Pedrosa, Fbd, Banas, E, Banerjee, P, Banerjee, S, Banfi, D, Bangert, A, Bansal, V, Bansil, H, Barak, L, Baranov, Sp, Barashkou, A, Galtieri, Ab, Barber, T, Barberio, El, Barberis, D, Barbero, M, Bardin, Dy, Barillari, T, Barisonzi, M, Barklow, T, Barlow, N, Barnett, Bm, Barnett, Rm, 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Bieniek, Sp, Biesiada, J, Biglietti, M, Bilokon, H, Bindi, M, Binet, S, Bingul, A, Bini, C, Biscarat, C, Bitenc, U, Black, Km, Blair, Re, Blanchard, Jb, Blanchot, G, Blazek, T, Blocker, C, Blocki, J, Blondel, A, Blum, W, Blumenschein, U, Bobbink, Gj, Bobrovnikov, Vb, Bocchetta, S, Bocci, A, Boddy, Cr, Boehler, M, Boek, J, Boelaert, N, Boser, S, Bogaerts, Ja, Bogdanchikov, A, Bogouch, A, Bohm, C, Boisvert, V, Bold, T, Boldea, V, Bolnet, Nm, Bona, M, Bondarenko, Vg, Boonekamp, M, Boorman, G, Booth, Cn, Bordoni, S, Borer, C, Borisov, A, Borissov, G, Borjanovic, I, Borroni, S, Bos, K, Boscherini, D, Bosman, M, Boterenbrood, H, Botterill, D, Bouchami, J, Boudreau, J, Bouhova Thacker, Ev, Boulahouache, C, Bourdarios, C, Bousson, N, Boveia, A, Boyd, J, Boyko, Ir, Bozhko, Ni, Bozovic Jelisavcic, I, Bracinik, J, Braem, A, Branchini, P, Brandenburg, Gw, Brandt, A, Brandt, G, Brandt, O, Bratzler, U, Brau, B, Brau, Je, Braun, Hm, Brelier, B, Bremer, J, Brenner, R, Bressler, S, Breton, D, Britton, D, Brochu, Fm, Brock, I, Brock, R, Brodbeck, Tj, Brodet, E, Broggi, F, Bromberg, C, Brooijmans, G, Brooks, Wk, Brown, G, Brown, H, de Renstrom, Pab, Bruncko, D, Bruneliere, R, Brunet, S, Bruni, A, Bruni, G, Bruschi, M, Buanes, T, Bucci, F, Buchanan, J, Buchanan, Nj, Buchholz, P, Buckingham, Rm, Buckley, Ag, Buda, Si, Budagov, Ia, Budick, B, Buscher, V, Bugge, L, Buira Clark, D, Bulekov, O, Bunse, M, Buran, T, Burckhart, H, Burdin, S, Burgess, T, Burke, S, Busato, E, Bussey, P, Buszello, Cp, Butin, F, Butler, B, Butler, Jm, Buttar, Cm, Butterworth, Jm, Buttinger, W, Byatt, T, Urban, Sc, Caforio, D, Cakir, O, Calafiura, P, Calderini, G, Calfayan, P, Calkins, R, Caloba, Lp, Caloi, R, Calvet, D, Calvet, S, Toro, Rc, Camarri, P, Cambiaghi, M, Cameron, D, Campana, S, Campanelli, M, Canale, V, Canelli, F, Canepa, A, Cantero, J, Capasso, L, Garrido, Mdmc, Caprini, I, Caprini, M, Capriotti, D, Capua, M, Caputo, R, Caramarcu, C, Cardarelli, R, Carli, T, Carlino, G, Carminati, L, Caron, B, Caron, S, Montoya, Gdc, Carter, Aa, Carter, Jr, Carvalho, J, Casadei, D, Casado, Mp, Cascella, M, Caso, C, Hernandez, Amc, Castaneda Miranda, E, Gimenez, Vc, Castro, Nf, Cataldi, G, Cataneo, F, Catinaccio, A, Catmore, Jr, Cattai, A, Cattani, G, Caughron, S, Cauz, D, Cavalleri, P, Cavalli, D, Cavalli Sforza, M, Cavasinni, V, Ceradini, Filippo, Chakraborty, D, Chan, K, Chapleau, B, Chapman, Jd, Chapman, Jw, Chareyre, E, Charlton, Dg, Chavda, V, Barajas, Cac, Cheatham, S, Chekanov, S, Chekulaev, Sv, Chelkov, Ga, Chelstowska, Ma, Chen, C, Chen, H, Chen, S, Chen, T, Chen, X, Cheng, S, Cheplakov, A, Chepurnov, Vf, El Moursli, Rc, Chernyatin, V, Cheu, E, Cheung, Sl, Chevalier, L, Chiefari, G, Chikovani, L, Childers, Jt, Chilingarov, A, Chiodini, G, Chizhov, Mv, Choudalakis, G, Chouridou, S, Christidi, Ia, Christov, A, Chromek Burckhart, D, Chu, Ml, Chudoba, J, Ciapetti, G, Ciba, K, Ciftci, Ak, Ciftci, R, Cinca, D, Cindro, V, Ciobotaru, Md, Ciocca, C, Ciocio, A, Cirilli, M, Ciubancan, M, Clark, A, Clark, Pj, Cleland, W, Clemens, Jc, Clement, B, Clement, C, Clifft, Rw, Coadou, Y, Cobal, M, Coccaro, A, Cochran, J, Coe, P, Cogan, Jg, Coggeshall, J, Cogneras, E, Cojocaru, Cd, Colas, J, Colijn, Ap, Collard, C, Collins, Nj, Collins Tooth, C, Collot, J, Colon, G, Muino, Pc, Coniavitis, E, Conidi, Mc, Consonni, M, Consorti, V, Constantinescu, S, Conta, C, Conventi, F, Cook, J, Cooke, M, Cooper, Bd, Cooper Sarkar, Am, Cooper Smith, Nj, Copic, K, Cornelissen, T, Corradi, M, Corriveau, F, Cortes Gonzalez, A, Cortiana, G, Costa, G, Costa, Mj, Costanzo, D, Costin, T, Cote, D, Torres, Rc, Courneyea, L, Cowan, G, Cowden, C, Cox, Be, Cranmer, K, Crescioli, F, Cristinziani, M, Crosetti, G, Crupi, R, Crepe Renaudin, S, Cuciuc, Cm, Almenar, Cc, Donszelmann, Tc, Cuneo, S, Curatolo, M, Curtis, Cj, Cwetanski, P, Czirr, H, Czyczula, Z, D'Auria, S, D'Onofrio, M, D'Orazio, A, Da Silva, Pvm, Da Via, C, Dabrowski, W, Dai, T, Dallapiccola, C, Dam, M, Dameri, M, Damiani, D, Danielsson, Ho, Dannheim, D, Dao, V, Darbo, G, Darlea, Gl, Daum, C, Dauvergne, Jp, Davey, W, Davidek, T, Davidson, N, Davidson, R, Davies, E, Davies, M, Davison, Ar, Davygora, Y, Dawe, E, Dawson, I, Dawson, Jw, Daya, Rk, De, K, de Asmundis, R, De Castro, S, Salgado, Pedf, De Cecco, S, de Graat, J, De Groot, N, de Jong, P, De la Taille, C, De la Torre, H, De Lotto, B, De Mora, L, De Nooij, L, Branco, Md, De Pedis, D, de Saintignon, P, De Salvo, A, De Sanctis, U, De Santo, A, De Regie, Jbd, Dean, S, Dedovich, Dv, Degenhardt, J, Dehchar, M, Deile, M, Del Papa, C, Del Peso, Jj, Del Prete, T, Deliyergiyev, M, Dell'Acqua, A, Dell'Asta, L, Della Pietra, M, della Volpe, D, Delmastro, M, Delpierre, P, Delruelle, N, Delsart, Pa, Deluca, C, Demers, S, Demichev, M, Demirkoz, B, Deng, J, Denisov, Sp, Derendarz, D, Derkaoui, Je, Derue, F, Dervan, P, Desch, K, Devetak, E, Deviveiros, Po, Dewhurst, A, Dewilde, B, Dhaliwal, S, Dhullipudi, R, Di Ciaccio, A, Di Ciaccio, L, Di Girolamo, A, Di Girolamo, B, Di Luise, S, Di Mattia, A, DI MICCO, Biagio, Di Nardo, R, Di Simone, A, Di Sipio, R, Dingfelder, J, Dionisi, C, Dita, P, Dita, S, Dittus, F, Djama, F, Djobava, T, do Vale, Mab, Wemans, Ad, Doan, Tko, Dobbs, M, Dobinson, R, Dobos, D, Dobson, E, Dobson, M, Dodd, J, Doglioni, C, Doherty, T, Doi, Y, Dolejsi, J, Dolenc, I, Dolezal, Z, Dolgoshein, Ba, Dohmae, T, Donadelli, M, Donega, M, Donini, J, Dopke, J, Doria, A, Dos Anjos, A, Dosil, M, Dotti, A, Dova, Mt, Dowell, Jd, Doxiadis, Ad, Doyle, At, Drasal, Z, Drees, J, Dressnandt, N, Drevermann, H, Driouichi, C, Dris, M, Dubbert, J, Dubbs, T, Dube, S, Duchovni, E, Duckeck, G, Dudarev, A, Dudziak, F, Duhrssen, M, Duerdoth, Ip, Duflot, L, Dufour, Ma, Dunford, M, Yildiz, Hd, Duxfield, R, Dwuznik, M, Dydak, F, Dzahini, D, Duren, M, Ebenstein, Wl, Ebke, J, Eckert, S, Eckweiler, S, Edmonds, K, Edwards, Ca, Edwards, Nc, Ehrenfeld, W, Ehrich, T, Eifert, T, Eigen, G, Einsweiler, K, Eisenhandler, E, Ekelof, T, El Kacimi, M, Ellert, M, Elles, S, Ellinghaus, F, Ellis, K, Ellis, N, 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Yoshida, R, Young, C, Youssef, S, Yu, D, Yu, J, Yuan, L, Yurkewicz, A, Zaets, Vg, Zaidan, R, Zaitsev, Am, Zajacova, Z, Zalite, Yk, Zanello, L, Zarzhitsky, P, Zaytsev, A, Zeitnitz, C, Zeller, M, Zemla, A, Zendler, C, Zenin, Av, Zenin, O, Zenis, T, Zenonos, Z, Zenz, S, Zerwas, D, della Porta, Gz, Zhan, Z, Zhang, D, Zhang, H, Zhang, J, Zhang, X, Zhang, Z, Zhao, L, Zhao, T, Zhao, Z, Zhemchugov, A, Zheng, S, Zhong, J, Zhou, B, Zhou, N, Zhou, Y, Zhu, Cg, Zhu, H, Zhu, J, Zhu, Y, Zhuang, X, Zhuravlov, V, Zieminska, D, Zimmermann, R, Zimmermann, S, Ziolkowski, M, Zitoun, R, Zivkovic, L, Zmouchko, Vv, Zobernig, G, Zoccoli, A, Zolnierowski, Y, Zsenei, A, zur Nedden, M, Zutshi, V, Zwalinski, L., ATLAS Collaboration (ukupan broj autora: 2996), Universidade do Minho, Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut Polytechnique de Grenoble - Grenoble Institute of Technology-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Joseph Fourier - Grenoble 1 (UJF)-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Pierre et Marie Curie - Paris 6 (UPMC), Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Pierre et Marie Curie - Paris 6 (UPMC)-AstroParticule et Cosmologie (APC (UMR_7164)), Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11), Massachusetts Institute of Technology. Department of Physics, Taylor, Frank E., Abdelalim Aly, Ahmed Aly, Alexandre, Gauthier, Backes, Moritz, Bell, Paul, Bell, William, Berglund, Frida Elina, Blondel, Alain, Bucci, Francesca, Clark, Allan Geoffrey, Dao, Valerio, Ferrere, Didier, Gadomski, Szymon, Garcia Navarro, Jose Enrique, Gaumer, Olivier, Gonzalez Sevilla, Sergio, Goulette, Marc, Hamilton, Andrew, Iacobucci, Giuseppe, Leger, Annie, Lister, Alison, Macina-Buono, Daniela, Martin Dit Latour, Bertrand, Mora Herrera, Maria Clemencia Rosario, Morone, Maria Cristina, Nektarijevic, Snezana, Nikolics, Katalin, Pasztor, Arpad, Pohl, Martin, Robichaud-Veronneau, Andrée, Rosbach, Kilian, Rosselet, Laurent, Wu, Xin, UAM. Departamento de Física Teórica, Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Institut Polytechnique de Grenoble - Grenoble Institute of Technology-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Aix Marseille Université (AMU), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7), Laboratoire d'Annecy de Physique des Particules (LAPP/Laboratoire d'Annecy-le-Vieux de Physique des Particules), G. AAD, E. ABAT, B. ABBOTT, J. ABDALLAH, A.A. ABDELALIM, A. ABDESSELAM, O. ABDINOV, B. ABI, M. ABOLINS, H. ABRAMOWICZ, H. ABREU, E. ACERBI, B.S. ACHARYA, M. ACKERS, D.L. ADAMS, T.N. ADDY, J. ADELMAN, M. ADERHOLZ, C. ADORISIO, P. ADRAGNA, T. ADYE, S. AEFSKY, J.A. AGUILAR-SAAVEDRA, M. AHARROUCHE, S.P. AHLEN, F. AHLES, A. AHMAD, H. AHMED, M. AHSAN, G. AIELLI, T. AKDOGAN, P.F. AKESSON, T.P.A. AKESSON, G. AKIMOTO, A.V. AKIMOV, A. AKTAS, M.S. ALAM, M.A. ALAM, J. ALBERT, S. ALBRAND, M. ALEKSA, I.N. ALEKSANDROV, M. ALEPPO, F. ALESSANDRIA, C. ALEXA, G. ALEXANDER, G. ALEXANDRE, T. ALEXOPOULOS, M. ALHROOB, M. ALIEV, G. ALIMONTI, J. ALISON, M. ALIYEV, P.P. ALLPORT, S.E. ALLWOOD-SPIERS, J. ALMOND, A. ALOISIO, R. ALON, A. ALONSO, J. ALONSO, M.G. ALVIGGI, K. AMAKO, P. AMARAL, G. AMBROSINI, G. AMBROSIO, C. AMELUNG, V.V. AMMOSOV, A. AMORIM, G. AMOROS, N. AMRAM, C. ANASTOPOULOS, T. ANDEEN, C.F. ANDERS, K.J. ANDERSON, A. ANDREAZZA, V. ANDREI, M.-L. ANDRIEUX, X.S. ANDUAGA, A. ANGERAMI, F. ANGHINOLFI, N. ANJOS, A. ANNOVI, A. ANTONAKI, M. ANTONELLI, S. ANTONELLI, J. ANTOS, B. ANTUNOVIC, F. ANULLI, S. AOUN, G. ARABIDZE, I. ARACENA, Y. ARAI, A.T.H. ARCE, J.P. ARCHAMBAULT, S. ARFAOUI, J.-F. ARGUIN, T. ARGYROPOULOS, E. ARIK, M. ARIK, A.J. ARMBRUSTER, K.E. ARMS, S.R. ARMSTRONG, O. ARNAEZ, C. ARNAULT, A. ARTAMONOV, D. ARUTINOV, M. ASAI, S. ASAI, R. ASFANDIYAROV, S. ASK, B. ASMAN, D. ASNER, L. ASQUITH, K. ASSAMAGAN, A. ASTBURY, A. ASTVATSATOUROV, B. ATHAR, G. ATOIAN, B. AUBERT, B. AUERBACH, E. AUGE, K. AUGSTEN, M. AUROUSSEAU, N. AUSTIN, G. AVOLIO, R. AVRAMIDOU, D. AXEN, C. AY, G. AZUELOS, Y. AZUMA, M.A. BAAK, G. BACCAGLIONI, C. BACCI, A.M. BACH, H. BACHACOU, K. BACHAS, G. BACHY, M. BACKES, E. BADESCU, P. BAGNAIA, Y. BAI, D.C. BAILEY, T. BAIN, J.T. BAINES, O.K. BAKER, M.D. BAKER, S. BAKER, F. BALTASAR DOS SANTOS PEDROSA, E. BANAS, P. BANERJEE, S. BANERJEE, D. BANFI, A. BANGERT, V. BANSAL, S.P. BARANOV, S. BARANOV, A. BARASHKOU, T. BARBER, E.L. BARBERIO, D. BARBERIS, M. BARBERO, D.Y. BARDIN, T. BARILLARI, M. BARISONZI, T. BARKLOW, N. BARLOW, B.M. BARNETT, R.M. BARNETT, A. BARONCELLI, M. BARONE, A.J. BARR, F. BARREIRO, J. BARREIRO GUIMARAES DA COSTA, P. BARRILLON, V. BARTHELD, H. BARTKO, R. BARTOLDUS, D. BARTSCH, R.L. BATES, S. BATHE, L. BATKOVA, J.R. BATLEY, A. BATTAGLIA, M. BATTISTIN, G. BATTISTONI, F. BAUER, H.S. BAWA, M. BAZALOVA, B. BEARE, T. BEAU, P.H. BEAUCHEMIN, R. BECCHERLE, N. BECERICI, P. BECHTLE, G.A. BECK, H.P. BECK, M. BECKINGHAM, K.H. BECKS, A.J. BEDDALL, A. BEDDALL, V.A. BEDNYAKOV, C. BEE, M. BEGEL, S. BEHAR HARPAZ, P.K. BEHERA, M. BEIMFORDE, G.A.N. BELANGER, C. BELANGER-CHAMPAGNE, B. BELHORMA, P.J. BELL, W.H. BELL, G. BELLA, L. BELLAGAMBA, F. BELLINA, G. BELLOMO, M. BELLOMO, A. BELLONI, K. BELOTSKIY, O. BELTRAMELLO, A. BELYMAM, S. BEN AMI, O. BENARY, D. BENCHEKROUN, C. BENCHOUK, M. BENDEL, B.H. BENEDICT, N. BENEKOS, Y. BENHAMMOU, G.P. BENINCASA, D.P. BENJAMIN, M. BENOIT, J.R. BENSINGER, K. BENSLAMA, S. BENTVELSEN, M. BERETTA, D. BERGE, E. BERGEAAS KUUTMANN, N. BERGER, F. BERGHAUS, E. BERGLUND, J. BERINGER, K. BERNARDET, P. BERNAT, R. BERNHARD, C. BERNIUS, T. BERRY, A. BERTIN, F. BERTINELLI, S. BERTOLUCCI, M.I. BESANA, N. BESSON, S. BETHKE, R.M. BIANCHI, M. BIANCO, O. BIEBEL, M. BIERI, J. BIESIADA, M. BIGLIETTI, H. BILOKON, M. BINDER, M. BINDI, S. BINET, A. BINGUL, C. BINI, C. BISCARAT, R. BISCHOF, U. BITENC, K.M. BLACK, R.E. BLAIR, O. BLANCH, J.-B. BLANCHARD, G. BLANCHOT, C. BLOCKER, J. BLOCKI, A. BLONDEL, W. BLUM, U. BLUMENSCHEIN, C. BOARETTO, G.J. BOBBINK, A. BOCCI, D. BOCIAN, R. BOCK, M. BOEHLER, M. BOEHM, J. BOEK, N. BOELAERT, S. BOSER, J.A. BOGAERTS, A. BOGOUCH, C. BOHM, J. BOHM, V. BOISVERT, T. BOLD, V. BOLDEA, A. BOLDYREV, V.G. BONDARENKO, M. BONDIOLI, R. BONINO, M. BOONEKAMP, G. BOORMAN, M. BOOSTEN, C.N. BOOTH, P.S.L. BOOTH, P. BOOTH, J.R.A. BOOTH, S. BORDONI, C. BORER, K. BORER, A. BORISOV, G. BORISSOV, I. BORJANOVIC, S. BORRONI, K. BOS, D. BOSCHERINI, M. BOSMAN, H. BOTERENBROOD, D. BOTTERILL, J. BOUCHAMI, J. BOUDREAU, E.V. BOUHOVA-THACKER, C. BOULAHOUACHE, C. BOURDARIOS, A. BOVEIA, J. BOYD, B.H. BOYER, I.R. BOYKO, N.I. BOZHKO, I. BOZOVIC-JELISAVCIC, S. BRACCINI, J. BRACINIK, A. BRAEM, E. BRAMBILLA, P. BRANCHINI, G.W. BRANDENBURG, A. BRANDT, G. BRANDT, O. BRANDT, U. BRATZLER, B. BRAU, J.E. BRAU, H.M. BRAUN, S. BRAVO, B. BRELIER, J. BREMER, R. BRENNER, S. BRESSLER, D. BRETON, N.D. BRETT, P.G. BRIGHT-THOMAS, D. BRITTON, F.M. BROCHU, I. BROCK, R. BROCK, T.J. BRODBECK, E. BRODET, F. BROGGI, C. BROMBERG, G. BROOIJMANS, W.K. BROOKS, G. BROWN, E. BRUBAKER, P.A. BRUCKMAN DE RENSTROM, D. BRUNCKO, R. BRUNELIERE, S. BRUNET, A. BRUNI, G. BRUNI, M. BRUSCHI, T. BUANES, F. BUCCI, J. BUCHANAN, N.J. BUCHANAN, P. BUCHHOLZ, A.G. BUCKLEY, I.A. BUDAGOV, B. BUDICK, V. BUSCHER, L. BUGGE, D. BUIRA-CLARK, E.J. BUIS, F. BUJOR, O. BULEKOV, M. BUNSE, T. BURAN, H. BURCKHART, S. BURDIN, T. BURGESS, S. BURKE, E. BUSATO, P. BUSSEY, C.P. BUSZELLO, F. BUTIN, B. BUTLER, J.M. BUTLER, C.M. BUTTAR, J.M. BUTTERWORTH, T. BYATT, J. CABALLERO, S. CABRERA URBAN, M. CACCIA, D. CAFORIO, O. CAKIR, P. CALAFIURA, G. CALDERINI, P. CALFAYAN, R. CALKINS, L.P. CALOBA, R. CALOI, D. CALVET, A. CAMARD, P. CAMARRI, M. CAMBIAGHI, D. CAMERON, J. CAMMIN, S. CAMPANA, M. CAMPANELLI, V. CANALE, F. CANELLI, A. CANEPA, J. CANTERO, L. CAPASSO, M.D.M. CAPEANS GARRIDO, I. CAPRINI, M. CAPRINI, M. CAPRIO, M. CAPUA, R. CAPUTO, C. CARAMARCU, R. CARDARELLI, L. CARDIEL SAS, T. CARLI, G. CARLINO, L. CARMINATI, B. CARON, S. CARON, C. CARPENTIERI, G.D. CARRILLO MONTOYA, S. CARRON MONTERO, A.A. CARTER, J.R. CARTER, J. CARVALHO, D. CASADEI, M.P. CASADO, M. CASCELLA, C. CASO, A.M. CASTANEDA HERNADEZ, E. CASTANEDA-MIRANDA, V. CASTILLO GIMENEZ, N.F. CASTRO, F. CASTROVILLARI, G. CATALDI, F. CATANEO, A. CATINACCIO, J.R. CATMORE, A. CATTAI, G. CATTANI, S. CAUGHRON, D. CAUZ, A. CAVALLARI, P. CAVALLERI, D. CAVALLI, M. CAVALLI-SFORZA, V. CAVASINNI, A. CAZZATO, F. CERADINI, C. CERNA, A.S. CERQUEIRA, A. CERRI, L. CERRITO, F. CERUTTI, M. CERVETTO, S.A. CETIN, F. CEVENINI, A. CHAFAQ, D. CHAKRABORTY, K. CHAN, J.D. CHAPMAN, J.W. CHAPMAN, E. CHAREYRE, D.G. CHARLTON, S. CHARRON, S. CHATTERJII, V. CHAVDA, S. CHEATHAM, S. CHEKANOV, S.V. CHEKULAEV, G.A. CHELKOV, H. CHEN, L. CHEN, S. CHEN, T. CHEN, X. CHEN, S. CHENG, A. CHEPLAKOV, V.F. CHEPURNOV, R. CHERKAOUI EL MOURSLI, V. TCHERNIATINE, D. CHESNEANU, E. CHEU, S.L. CHEUNG, L. CHEVALIER, F. CHEVALLIER, V. CHIARELLA, G. CHIEFARI, L. CHIKOVANI, J.T. CHILDERS, A. CHILINGAROV, G. CHIODINI, V. CHIZHOV, G. CHOUDALAKIS, S. CHOURIDOU, T. CHRISTIANSEN, I.A. CHRISTIDI, A. CHRISTOV, D. CHROMEK-BURCKHART, M.L. CHU, J. CHUDOBA, G. CIAPETTI, E. CICALINI, A.K. CIFTCI, R. CIFTCI, D. CINCA, V. CINDRO, M.D. CIOBOTARU, C. CIOCCA, A. CIOCIO, M. CIRILLI, M. CITTERIO, A. CLARK, P.J. CLARK, W. CLELAND, J.C. CLEMENS, B. CLEMENT, C. CLEMENT, D. CLEMENTS, R.W. CLIFFT, Y. COADOU, M. COBAL, A. COCCARO, J. COCHRAN, R. COCO, P. COE, S. COELLI, J. COGGESHALL, E. COGNERAS, C.D. COJOCARU, J. COLAS, B. COLE, A.P. COLIJN, C. COLLARD, N.J. COLLINS, C. COLLINS-TOOTH, J. COLLOT, G. COLON, R. COLUCCIA, G. COMUNE, P. CONDE MUINO, E. CONIAVITIS, M. CONSONNI, S. CONSTANTINESCU, C. CONTA, F. CONVENTI, J. COOK, M. COOKE, B.D. COOPER, A.M. COOPER-SARKAR, N.J. COOPER-SMITH, K. COPIC, T. CORNELISSEN, M. CORRADI, S. CORREARD, F. CORRIVEAU, A. CORSO-RADU, A. CORTES-GONZALEZ, G. CORTIANA, G. COSTA, M.J. COSTA, D. COSTANZO, T. COSTIN, D. COTE, R. COURA TORRES, L. COURNEYEA, C. COUYOUMTZELIS, G. COWAN, C. COWDEN, B.E. COX, K. CRANMER, J. CRANSHAW, M. CRISTINZIANI, G. CROSETTI, R. CRUPI, S. CREPE-RENAUDIN, C. CUENCA ALMENAR, T. CUHADAR DONSZELMANN, S. CUNEO, A. CUNHA, M. CURATOLO, C.J. CURTIS, P. CWETANSKI, Z. CZYCZULA, S. D'AURIA, M. D'ONOFRIO, A. D'ORAZIO, A. DA ROCHA GESUALDI MELLO, P.V.M. DA SILVA, C. DA VIA, W. DABROWSKI, A. DAHLHOFF, T. DAI, C. DALLAPICCOLA, S.J. DALLISON, J. DALMAU, C.H. DALY, M. DAM, M. DAMERI, H.O. DANIELSSON, R. DANKERS, D. DANNHEIM, V. DAO, G. DARBO, G.L. DARLEA, C. DAUM, J.P. DAUVERGNE, W. DAVEY, T. DAVIDEK, D.W. DAVIDSON, N. DAVIDSON, R. DAVIDSON, M. DAVIES, A.R. DAVISON, I. DAWSON, J.W. DAWSON, R.K. DAYA, K. DE, R. DE ASMUNDIS, S. DE CASTRO, P.E. DE CASTRO FARIA SALGADO, S. DE CECCO, J. DE GRAAT, N. DE GROOT, P. DE JONG, E. DE LA CRUZ-BURELO, C. DE LA TAILLE, B. DE LOTTO, L. DE MORA, M. DE OLIVEIRA BRANCO, D. DE PEDIS, P. DE SAINTIGNON, A. DE SALVO, U. DE SANCTIS, A. DE SANTO, J.B. DE VIVIE DE REGIE, G. DE ZORZI, S. DEAN, H. DEBERG, G. DEDES, D.V. DEDOVICH, P.O. DEFAY, J. DEGENHARDT, M. DEHCHAR, M. DEILE, C. DEL PAPA, J. DEL PESO, T. DEL PRETE, A. DELL'ACQUA, L. DELL'ASTA, M. DELLA PIETRA, D. DELLA VOLPE, M. DELMASTRO, P. DELPIERRE, N. DELRUELLE, P.A. DELSART, C. DELUCA, S. DEMERS, M. DEMICHEV, B. DEMIRKOZ, J. DENG, W. DENG, S.P. DENISOV, C. DENNIS, J.E. DERKAOUI, F. DERUE, P. DERVAN, K. DESCH, P.O. DEVIVEIROS, A. DEWHURST, B. DEWILDE, S. DHALIWAL, R. DHULLIPUDI, A. DI CIACCIO, L. DI CIACCIO, A. DI DOMENICO, A. DI GIROLAMO, B. DI GIROLAMO, S. DI LUISE, A. DI MATTIA, R. DI NARDO, A. DI SIMONE, R. DI SIPIO, M.A. DIAZ, M.M. DIAZ GOMEZ, F. DIBLEN, E.B. DIEHL, H. DIETL, J. DIETRICH, T.A. DIETZSCH, S. DIGLIO, K. DINDAR YAGCI, D.J. DINGFELDER, C. DIONISI, R. DIPANJAN, P. DITA, S. DITA, F. DITTUS, F. DJAMA, R. DJILKIBAEV, T. DJOBAVA, M.A.B. DO VALE, A. DO VALLE WEMANS, T.K.O. DOAN, M. DOBBS, R. DOBINSON, D. DOBOS, E. DOBSON, M. DOBSON, J. DODD, O.B. DOGAN, C. DOGLIONI, T. DOHERTY, Y. DOI, J. DOLEJSI, I. DOLENC, Z. DOLEZAL, B.A. DOLGOSHEIN, T. DOHMAE, E. DOMINGO, M. DONEGA, J. DONINI, J. DOPKE, A. DORIA, A. DOS ANJOS, M. DOSIL, A. DOTTI, M.T. DOVA, J.D. DOWELL, A. DOXIADIS, A.T. DOYLE, J. DRAGIC, D. DRAKOULAKOS, Z. DRASAL, J. DREES, N. DRESSNANDT, H. DREVERMANN, C. DRIOUICHI, M. DRIS, J.G. DROHAN, J. DUBBERT, T. DUBBS, E. DUCHOVNI, G. DUCKECK, A. DUDAREV, F. DUDZIAK, M. DUHRSSEN, H. DUR, I.P. DUERDOTH, L. DUFLOT, M.-A. DUFOUR, M. DUNFORD, H. DURAN YILDIZ, A. DUSHKIN, R. DUXFIELD, M. DWUZNIK, F. DYDAK, D. DZAHINI, M. DUREN, W.L. EBENSTEIN, J. EBKE, S. ECKERT, S. ECKWEILER, K. EDMONDS, C.A. EDWARDS, I. EFTHYMIOPOULOS, K. EGOROV, W. EHRENFELD, T. EHRICH, T. EIFERT, G. EIGEN, K. EINSWEILER, E. EISENHANDLER, T. EKELOF, M. EL KACIMI, M. ELLERT, S. ELLES, F. ELLINGHAUS, K. ELLIS, N. ELLIS, J. ELMSHEUSER, M. ELSING, R. ELY, D. EMELIYANOV, R. ENGELMANN, A. ENGL, B. EPP, A. EPPIG, J. ERDMANN, A. EREDITATO, V. EREMIN, D. ERIKSSON, I. ERMOLINE, J. ERNST, M. ERNST, J. ERNWEIN, D. ERREDE, S. ERREDE, E. ERTEL, M. ESCALIER, C. ESCOBAR, X. ESPINAL CURULL, B. ESPOSITO, F. ETIENNE, A.I. ETIENVRE, E. ETZION, H. EVANS, V.N. EVDOKIMOV, L. FABBRI, C. FABRE, K. FACIUS, R.M. FAKHRUTDINOV, S. FALCIANO, A.C. FALOU, Y. FANG, M. FANTI, A. FARBIN, A. FARILLA, J. FARLEY, T. FAROOQUE, S.M. FARRINGTON, P. FARTHOUAT, P. FASSNACHT, D. FASSOULIOTIS, B. FATHOLAHZADEH, L. FAYARD, F. FAYETTE, R. FEBBRARO, P. FEDERIC, O.L. FEDIN, I. FEDORKO, W. FEDORKO, L. FELIGIONI, C.U. FELZMANN, C. FENG, E.J. FENG, A.B. FENYUK, J. FERENCEI, J. FERLAND, B. FERNANDES, W. FERNANDO, S. FERRAG, J. FERRANDO, V. FERRARA, A. FERRARI, P. FERRARI, R. FERRARI, A. FERRER, M.L. FERRER, D. FERRERE, C. FERRETTI, F. FERRO, M. FIASCARIS, S. FICHET, F. FIEDLER, A. FILIPCIC, A. FILIPPAS, F. FILTHAUT, M. FINCKE-KEELER, M.C.N. FIOLHAIS, L. FIORINI, A. FIRAN, G. FISCHER, P. FISCHER, M.J. FISHER, S.M. FISHER, H.F. FLACHER, J. FLAMMER, I. FLECK, J. FLECKNER, P. FLEISCHMANN, S. FLEISCHMANN, F. FLEURET, T. FLICK, L.R. FLORES CASTILLO, M.J. FLOWERDEW, F. FOHLISCH, M. FOKITIS, T. FONSECA MARTIN, J. FOPMA, D.A. FORBUSH, A. FORMICA, A. FORTI, D. FORTIN, J.M. FOSTER, D. FOURNIER, A. FOUSSAT, A.J. FOWLER, K. FOWLER, H. FOX, P. FRANCAVILLA, M. FRANCHINI, S. FRANCHINO, D. FRANCIS, M. FRANKLIN, S. FRANZ, M. FRATERNALI, S. FRATINA, J. FREESTONE, S.T. FRENCH, R. FROESCHL, D. FROIDEVAUX, J.A. FROST, C. FUKUNAGA, E. FULLANA TORREGROSA, J. FUSTER, C. GABALDON, O. GABIZON, T. GADFORT, S. GADOMSKI, G. GAGLIARDI, P. GAGNON, C. GALEA, E.J. GALLAS, M.V. GALLAS, V. GALLO, B.J. GALLOP, P. GALLUS, E. GALYAEV, K.K. GAN, Y.S. GAO, V.A. GAPIENKO, A. GAPONENKO, M. GARCIA-SCIVERES, C. GARCIA, J.E. GARCIA NAVARRO, V. GARDE, R.W. GARDNER, N. GARELLI, H. GARITAONANDIA, V. GARONNE, J. GARVEY, C. GATTI, G. GAUDIO, O. GAUMER, P. GAUZZI, I.L. GAVRILENKO, C. GAY, G. GAYCKEN, J.-C. GAYDE, E.N. GAZIS, P. GE, C.N.P. GEE, CH. GEICH-GIMBEL, K. GELLERSTEDT, C. GEMME, M.H. GENEST, S. GENTILE, F. GEORGATOS, S. GEORGE, P. GERLACH, A. GERSHON, C. GEWENIGER, H. GHAZLANE, P. GHEZ, N. GHODBANE, B. GIACOBBE, S. GIAGU, V. GIAKOUMOPOULOU, V. GIANGIOBBE, F. GIANOTTI, B. GIBBARD, A. GIBSON, S.M. GIBSON, G.F. GIERALTOWSKI, L.M. GILBERT, M. GILCHRIESE, O. GILDEMEISTER, V. GILEWSKY, A.R. GILLMAN, D.M. GINGRICH, J. GINZBURG, N. GIOKARIS, M.P. GIORDANI, R. GIORDANO, F.M. GIORGI, P. GIOVANNINI, P.F. GIRAUD, P. GIRTLER, D. GIUGNI, P. GIUSTI, B.K. GJELSTEN, L.K. GLADILIN, C. GLASMAN, A. GLAZOV, K.W. GLITZA, G.L. GLONTI, K.G. GNANVO, J. GODFREY, J. GODLEWSKI, M. GOEBEL, T. GOPFERT, C. GOERINGER, C. 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TSYBYCHEV, J.M. TUGGLE, M. TURALA, D. TURECEK, I. TURK CAKIR, E. TURLAY, P.M. TUTS, M.S. TWOMEY, M. TYLMAD, M. TYNDEL, D. TYPALDOS, H. TYRVAINEN, E. TZAMARIOUDAKI, G. TZANAKOS, K. UCHIDA, I. UEDA, M. UGLAND, M. UHLENBROCK, M. UHRMACHER, F. UKEGAWA, G. UNAL, D.G. UNDERWOOD, A. UNDRUS, G. UNEL, Y. UNNO, D. URBANIEC, E. URKOVSKY, P. URQUIJO, P. URREJOLA, G. USAI, M. USLENGHI, L. VACAVANT, V. VACEK, B. VACHON, S. VAHSEN, C. VALDERANIS, J. VALENTA, P. VALENTE, S. VALENTINETTI, S. VALKAR, E. VALLADOLID GALLEGO, S. VALLECORSA, J.A. VALLS FERRER, R. VAN BERG, H. VAN DER GRAAF, E. VAN DER KRAAIJ, E. VAN DER POEL, D. VAN DER STER, B. VAN EIJK, N. VAN ELDIK, P. VAN GEMMEREN, Z. VAN KESTEREN, I. VAN VULPEN, W. VANDELLI, G. VANDONI, A. VANIACHINE, P. VANKOV, F. VANNUCCI, F. VARELA RODRIGUEZ, R. VARI, E.W. VARNES, D. VAROUCHAS, A. VARTAPETIAN, K.E. VARVELL, L. VASILYEVA, V.I. VASSILAKOPOULOS, F. VAZEILLE, G. VEGNI, J.J. VEILLET, C. VELLIDIS, F. VELOSO, R. VENESS, S. VENEZIANO, A. VENTURA, D. VENTURA, S. VENTURA, M. VENTURI, N. VENTURI, V. VERCESI, M. VERDUCCI, W. VERKERKE, J.C. VERMEULEN, L. VERTOGARDOV, M.C. VETTERLI, I. VICHOU, T. VICKEY, G.H.A. VIEHHAUSER, M. VILLA, E.G. VILLANI, M. VILLAPLANA PEREZ, E. VILUCCHI, P. VINCENT, M.G. VINCTER, E. VINEK, V.B. VINOGRADOV, M. VIRCHAUX, S. VIRET, J. VIRZI, O. VITELLS, I. VIVARELLI, F. VIVES VAQUE, S. VLACHOS, M. VLASAK, N. VLASOV, A. VOGEL, H. VOGT, P. VOKAC, C.F. VOLLMER, M. VOLPI, G. VOLPINI, H. VON DER SCHMITT, J. VON LOEBEN, H. VON RADZIEWSKI, E. VON TOERNE, V. VOROBEL, A.P. VOROBIEV, V. VORWERK, M. VOS, K.C. VOSS, R. VOSS, T.T. VOSS, J.H. VOSSEBELD, A.S. VOVENKO, N. VRANJES, M. VRANJES MILOSAVLJEVIC, V. VRBA, M. VREESWIJK, T. VU ANH, B. VUARIDEL, D. VUDRAGOVIC, R. VUILLERMET, I. VUKOTIC, A. WAANANEN, P. WAGNER, H. WAHLEN, J. WALBERSLOH, J. WALDER, R. WALKER, W. WALKOWIAK, R. WALL, S. WALSH, C. WANG, H. WANG, J. WANG, J.C. WANG, M.W. WANG, S.M. WANG, F. WAPPLER, A. WARBURTON, C.P. WARD, M. WARSINSKY, R. WASTIE, P.M. WATKINS, A.T. WATSON, M.F. WATSON, G. WATTS, S. WATTS, A.T. WAUGH, B.M. WAUGH, M. WEBEL, G. WEBER, J. WEBER, M.D. WEBER, M. WEBER, M.S. WEBER, P. WEBER, A.R. WEIDBERG, J. WEINGARTEN, C. WEISER, H. WELLENSTEIN, H.P. WELLISCH, P.S. WELLS, M. WEN, T. WENAUS, S. WENDLER, T. WENGLER, S. WENIG, N. WERMES, M. WERNER, P. WERNER, M. WERTH, U. WERTHENBACH, M. WESSELS, K. WHALEN, S.J. WHEELER-ELLIS, S.P. WHITAKER, A. WHITE, M.J. WHITE, S. WHITE, S.R. WHITEHEAD, D. WHITESON, D. WHITTINGTON, F. WICEK, D. WICKE, F.J. WICKENS, W. WIEDENMANN, M. WIELERS, P. WIENEMANN, M. WIESMANN, C. WIGLESWORTH, L.A.M. WIIK, A. WILDAUER, M.A. WILDT, I. WILHELM, H.G. WILKENS, E. WILLIAMS, H.H. WILLIAMS, W. WILLIS, S. WILLOCQ, J.A. WILSON, M.G. WILSON, A. WILSON, I. WINGERTER-SEEZ, F. WINKLMEIER, M. WITTGEN, E. WOEHRLING, M.W. WOLTER, H. WOLTERS, B.K. WOSIEK, J. WOTSCHACK, M.J. WOUDSTRA, K. WRAIGHT, C. WRIGHT, D. WRIGHT, B. WRONA, S.L. WU, X. WU, J. WUESTENFELD, E. WULF, R. WUNSTORF, B.M. WYNNE, L. XAPLANTERIS, S. XELLA, S. XIE, Y. XIE, D. XU, G. XU, N. XU, M. YAMADA, A. YAMAMOTO, K. YAMAMOTO, S. YAMAMOTO, T. YAMAMURA, J. YAMAOKA, T. YAMAZAKI, Y. YAMAZAKI, Z. YAN, H. YANG, S. YANG, U.K. YANG, Y. YANG, Z. YANG, W.-M. YAO, Y. YAO, K. YARRADODDI, Y. YASU, J. YE, S. YE, M. YILMAZ, R. YOOSOOFMIYA, K. YORITA, H. YOSHIDA, R. YOSHIDA, C. YOUNG, S.P. YOUSSEF, D. YU, J. YU, J. YUAN, L. YUAN, A. YURKEWICZ, V.G. ZAETS, R. ZAIDAN, A.M. ZAITSEV, Z. ZAJACOVA, YO.K. ZALITE, V. ZAMBRANO, L. ZANELLO, P. ZARZHITSKY, A. ZAYTSEV, M. ZDRAZIL, C. ZEITNITZ, M. ZELLER, P.F. ZEMA, A. ZEMLA, C. ZENDLER, A.V. ZENIN, O. ZENIN, T. ZENIS, Z. ZENONOS, S. ZENZ, D. ZERWAS, G. ZEVI DELLA PORTA, Z. ZHAN, H. ZHANG, J. ZHANG, Q. ZHANG, X. ZHANG, L. ZHAO, T. ZHAO, Z. ZHAO, A. ZHEMCHUGOV, S. ZHENG, J. ZHONG, B. ZHOU, N. ZHOU, Y. ZHOU, C.G. ZHU, H. ZHU, Y. ZHU, X. ZHUANG, V. ZHURAVLOV, B. ZILKA, R. ZIMMERMANN, S. ZIMMERMANN, M. ZIOLKOWSKI, R. ZITOUN, L. ZIVKOVIC, V.V. ZMOUCHKO, G. ZOBERNIG, A. ZOCCOLI, Y. ZOLNIEROWSKI, A. ZSENEI, M. ZUR NEDDEN, and V. ZUTSHI
Subjects: Nuclear and High Energy Physics, Particle physics, Atlas detector, Ciências Naturais::Ciências Físicas, Physics::Instrumentation and Detectors, Ciências Físicas [Ciências Naturais], FOS: Physical sciences, ddc:500.2, SUSY, ATLAS, Long-lived particles, 01 natural sciences, CHARGED PARTICLES, High Energy Physics - Experiment, Nuclear physics, High Energy Physics - Experiment (hep-ex), Muon spectrometer, Atlas (anatomy), 0103 physical sciences, medicine, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], ddc:530, High Energy Physics, 010306 general physics, Nuclear Experiment, Physics, Science & Technology, ATLAS detector, 010308 nuclear & particles physics, High Energy Physics::Phenomenology, Settore FIS/01 - Fisica Sperimentale, Física, Supersymmetry, Charged particle, medicine.anatomical_structure, HADRON-HADRON COLLISIONS, R-hadron, Experimental High Energy Physics, ComputingMethodologies_DOCUMENTANDTEXTPROCESSING, Física nuclear, High Energy Physics::Experiment, LHC, supersymmetry, Particle Physics - Experiment
Abstract: A search for long-lived charged particles reaching the muon spectrometer is performed using a data sample of 37 pb[superscript −1] from pp collisions at √s = 7 TeV collected by the ATLAS detector at the LHC in 2010. No excess is observed above the estimated background. Stable [~ over τ] sleptons are excluded at 95% CL up to a mass of 136 GeV, in GMSB models with N[subscript 5] = 3, mmessenger = 250 TeV, sign(μ) = 1 and tanβ = 5. Electroweak production of sleptons is excluded up to a mass of 110 GeV. Gluino R-hadrons in a generic interaction model are excluded up to masses of 530 GeV to 544 GeV depending on the fraction of R-hadrons produced as [~ over g]-balls., European Organization for Nuclear Research, Brookhaven National Laboratory, United States. Dept. of Energy, National Science Foundation (U.S.)
Published: 2011
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3. Diagnosis and management of dural arteriovenous fistulas: A 10 years single-center experience

Author: Signorelli, F., Della Pepa, Giuseppe Maria, Sabatino, Giovanni, Marchese, Enrico, Tardugno, Maira, Puca, Alfredo, Albanese, Alessio, Della Pepa G. M. (ORCID:0000-0001-8698-3359), Sabatino G. (ORCID:0000-0002-4227-0434), Marchese E. (ORCID:0000-0001-8551-0357), Maira G., Puca A. (ORCID:0000-0001-6096-1776), Albanese A. (ORCID:0000-0001-8783-2974), Signorelli, F., Della Pepa, Giuseppe Maria, Sabatino, Giovanni, Marchese, Enrico, Tardugno, Maira, Puca, Alfredo, Albanese, Alessio, Della Pepa G. M. (ORCID:0000-0001-8698-3359), Sabatino G. (ORCID:0000-0002-4227-0434), Marchese E. (ORCID:0000-0001-8551-0357), Maira G., Puca A. (ORCID:0000-0001-6096-1776), and Albanese A. (ORCID:0000-0001-8783-2974)
Abstract: Objectives Dural arteriovenous fistulas (DAVFs) are a challenging condition in vascular neurosurgery. Disease natural history and its management is still debated. In the present paper we report our center series on DAVFs over a period of 10 years. Our data were compared with relevant literature. Patient and methods Our series includes 45 cases: 14 cavernous sinus, 11 transverse-sigmoid, 8 patients tentorial, 6 anterior cranial fossa, 5 patients spinal, 1 patient foramen magnum. Results and conclusions DVAFs distribution, clinical presentation and hemorrhagic risk are discussed. Cavernous sinus DAVFs are the most common site in our series. Other locations in order of frequency are transverse-sigmoid sinus, tentorial, anterior cranial fossa, spinal and foramen magnum. The majority of patients presented with non-aggressive symptoms. 18% presented with intracranial hemorrhage: all the hemorrhages occurred in high-grade DAVFs. For most patients, endovascular treatment, transarterial or transvenous, was the first option. Surgery was performed for the anterior cranial fossa DAVFs and other complex lesions draining mostly transverse-sigmoid sinus and tentorium. In 7% of cases a combination of endovascular + surgical treatment was used. Our series has been carefully analyzed in comparison 'side by side' with most relevant literature on DVAFs, focusing particularly on management strategies, therapeutic options and risks related to treatment.
Published: 2015

4. Protective effect of external ventricular drainage on cerebral vasospasm. A retrospective study on aneurysmal SAH treated endovascularly

Author: Della Pepa, Giuseppe Maria, Scerrati, A., Albanese, Alessio, Marchese, Enrico, Tardugno, Maira, Sabatino, Giovanni, Della Pepa G. M. (ORCID:0000-0001-8698-3359), Albanese A. (ORCID:0000-0001-8783-2974), Marchese E. (ORCID:0000-0001-8551-0357), Maira G., Sabatino G. (ORCID:0000-0002-4227-0434), Della Pepa, Giuseppe Maria, Scerrati, A., Albanese, Alessio, Marchese, Enrico, Tardugno, Maira, Sabatino, Giovanni, Della Pepa G. M. (ORCID:0000-0001-8698-3359), Albanese A. (ORCID:0000-0001-8783-2974), Marchese E. (ORCID:0000-0001-8551-0357), Maira G., and Sabatino G. (ORCID:0000-0002-4227-0434)
Abstract: Objective Cerebral vasospasm (VS) is one of the factors that can most significantly worsen the prognosis after aneurysmal subarachnoid hemorrhage (SAH). A substantial body of evidence supports the idea that CSF diversion could prevent VS, even if this issue is still much debated. External ventricular drainage (EVD) is the recommended procedure for post-hemorrhagic hydrocephalus. In this study we analyzed whether EVD, placed for acute hydrocephalus, is effective in reducing the incidence of clinical and radiological cerebral vasospasm in patients who underwent endovascular treatment for aneurysmal SAH. Patients and methods We retrospectively studied the incidence of radiologically confirmed VS in 141 patients treated endovascularly for aneurysmal SAH: 80 underwent EVD for hydrocephalus, 61 did not undergo EVD. Results VS occurred in 8.75% of cases (7 patients) in the first groups, while in 22.95% (14 patients) in the second group. In addition, patients not treated with EVD display a prevalence of VS in lower Fisher grades compared to the other group. Conclusion Our data indicate that CSF drainage reduces the risk of vasospasms in patients with endovascular treatment for aneurysmal SAH. © 2014 Elsevier B.V.
Published: 2014

5. Autologous dural substitutes: A prospective study

Author: Sabatino, Giovanni, Della Pepa, Giuseppe Maria, Bianchi, F., Capone, G., Rigante, L., Albanese, Alessio, Maira, G., Marchese, Enrico, Sabatino G. (ORCID:0000-0002-4227-0434), Della Pepa G. M. (ORCID:0000-0001-8698-3359), Albanese A. (ORCID:0000-0001-8783-2974), Marchese E. (ORCID:0000-0001-8551-0357), Sabatino, Giovanni, Della Pepa, Giuseppe Maria, Bianchi, F., Capone, G., Rigante, L., Albanese, Alessio, Maira, G., Marchese, Enrico, Sabatino G. (ORCID:0000-0002-4227-0434), Della Pepa G. M. (ORCID:0000-0001-8698-3359), Albanese A. (ORCID:0000-0001-8783-2974), and Marchese E. (ORCID:0000-0001-8551-0357)
Abstract: Objective Duraplasty can be performed both by means of autologous tissues (such as galea-pericranium, temporal muscle, fascia lata) or by commercially available dural patches. Nowadays many neurosurgeons consider galea-pericranium duraplasty time-consuming, technically demanding or not adequate, thus dural surrogates are increasingly popular. In this prospective research we compared duraplasty using autologous galea-pericranium vs. dural patches in terms of postoperative long term results, ease/time required and costs. Patients and methods Research has been designed as prospective cohort study, that included 185 patients undergoing supratentorial elective neurosurgery with galea-pericranium or non-autologous duraplasty (minimum follow-up 12 months). Variables taken into account were: wound infection, CSF fistula, subcutaneous CSF collection, bone flap osteitis, brain abscess, empyema and tardive wound dehiscence (particularly after postoperative radiotherapy). Time for galea-pericranium collection, size of galea-pericranium harvest and dural defects were recorded in each case. Costs for non-autologous duroplasty were calculated. Results No statistically significant differences were evident in long term postoperative results between the two groups. Mean time of galea-pericranium collection is less than 2 min and enough galea-pericranium can be harvested in supratentorial approach to cover almost any dural defect. The only difference between the two groups is costs: an average of 268.7€/patient spent just for duraplasty. This figure is surely substantial if considered for the entire amount of surgeries performed in a department. Conclusions Considering that in our study long term results are equivalent, that galea-pericranium duraplasty is feasible and rapid, our indications are in favor of saving a considerable amount of money since an ideal autologous dural substitute is available and "free". © 2013 Elsevier B.V. All rights reserved.
Published: 2014

6. Indocyanine green video-angiography in neurosurgery: A glance beyond vascular applications

Author: Scerrati, A., Della Pepa, Giuseppe Maria, Conforti, G., Sabatino, Giovanni, Puca, Alfredo, Albanese, Alberto, Tardugno, Maira, Marchese, Enrico, Esposito, G., Della Pepa G. M. (ORCID:0000-0001-8698-3359), Sabatino G. (ORCID:0000-0002-4227-0434), Puca A. (ORCID:0000-0001-6096-1776), Albanese A. (ORCID:0000-0002-5864-0006), Maira G., Marchese E. (ORCID:0000-0001-8551-0357), Scerrati, A., Della Pepa, Giuseppe Maria, Conforti, G., Sabatino, Giovanni, Puca, Alfredo, Albanese, Alberto, Tardugno, Maira, Marchese, Enrico, Esposito, G., Della Pepa G. M. (ORCID:0000-0001-8698-3359), Sabatino G. (ORCID:0000-0002-4227-0434), Puca A. (ORCID:0000-0001-6096-1776), Albanese A. (ORCID:0000-0002-5864-0006), Maira G., and Marchese E. (ORCID:0000-0001-8551-0357)
Abstract: Objective Indocyanine green video angiography (ICG-VA) is a non invasive, easy to use and a very useful tool for various neurosurgical procedures. Initially introduced in vascular neurosurgery since 2003, it's applications have broadened over time, both in vascular applications and in other neurosurgical fields. The objective of our study is to review all published literature about ICG-VA, cataloguing its different applications. Methods A systematic review of all pertinent literature articles published from January 2003 to May 2014 using Pubmed access was performed using pertinent keywords; cross check of references of selected articles was performed in order to complete bibliographical research. Results of research were grouped by pathology. Results and conclusions The paper systematically analyses ICG-VA different applications in neurosurgery, from vascular neurosurgery to tumor resection and endoscopic applications, focusing on reported advantages and disadvantages, and discussing future perspectives. © 2014 Elsevier B.V.
Published: 2014

7. Indocyanine green video-angiography in neurosurgery: A glance beyond vascular applications

Author: Scerrati, Alba, Della Pepa, G M, Conforti, G, Sabatino, G, Puca, A, Albanese, A, Maira, G, Marchese, E, Esposito, G, Scerrati, Alba, Della Pepa, G M, Conforti, G, Sabatino, G, Puca, A, Albanese, A, Maira, G, Marchese, E, and Esposito, G
Abstract: OBJECTIVE: Indocyanine green video angiography (ICG-VA) is a non invasive, easy to use and a very useful tool for various neurosurgical procedures. Initially introduced in vascular neurosurgery since 2003, it's applications have broadened over time, both in vascular applications and in other neurosurgical fields. The objective of our study is to review all published literature about ICG-VA, cataloguing its different applications. METHODS: A systematic review of all pertinent literature articles published from January 2003 to May 2014 using Pubmed access was performed using pertinent keywords; cross check of references of selected articles was performed in order to complete bibliographical research. Results of research were grouped by pathology. RESULTS AND CONCLUSIONS: The paper systematically analyses ICG-VA different applications in neurosurgery, from vascular neurosurgery to tumor resection and endoscopic applications, focusing on reported advantages and disadvantages, and discussing future perspectives.
Published: 2014

8. In Reply to the Letter to the Editor Regarding: Preventing Ventricular Catheter Displacement and Infection with the "Catheter-Locking Device-Assisted" Technique: A Retrospective Study of 231 Patients.

Author: Piccirilli M, Scafa AK, Marchese E, Gallo M, and Santoro A
Subjects: Humans, Retrospective Studies, Catheters, Indwelling, Catheter-Related Infections prevention & control
Published: 2024
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9. On the dual role of (+)-catechin as primary antioxidant and inhibitor of viral proteases.

Author: Ciardullo G, Orlando C, Russo N, Marchese E, Galano A, Marino T, and Prejanò M
Subjects: Antiviral Agents chemistry, Antiviral Agents pharmacology, Humans, Coronavirus 3C Proteases antagonists & inhibitors, Coronavirus 3C Proteases metabolism, Coronavirus 3C Proteases chemistry, Catechin chemistry, Catechin pharmacology, Antioxidants chemistry, Antioxidants pharmacology, Antioxidants metabolism, SARS-CoV-2 drug effects, Protease Inhibitors chemistry, Protease Inhibitors pharmacology, Molecular Dynamics Simulation
Abstract: Natural antioxidants have become the subject of many investigations due to the role that they play in the reduction of oxidative stress. Their main scavenging mechanisms concern the direct inactivation of free radicals and the coordination of metal ions involved in Fenton-like reactions. Recently, increasing attention has been paid to non-covalent inhibition of enzymes involved in different diseases by the antioxidants. Here, a computational investigation on the primary antioxidant power of (+)-catechin against the • OOH radical has been performed in both lipid-like and aqueous environments, taking into account the relevant species present in the simulated acid-base equilibria at the physiological pH. Hydrogen Atom Transfer (HAT), Single Electron Transfer (SET), and Radical Adduct Formation (RAF) mechanisms were studied, and relative rate constants were estimated. The potential inhibitory activity of the (+)-catechin towards the most important proteases from SARS-CoV-2, 3C-like (M pro ) and papain-like (PL pro ) proteases was also investigated by MD simulations to provide deeper atomistic insights on the binding sites. Based on the antioxidant and antiviral properties also unravelled by comparison with other molecules having similar chemical scaffold, our results propose that (+)-CTc satisfies can explicate a dual action as antioxidant and antiviral in particular versus M pro from SARS-CoV-2., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 The Authors. Published by Elsevier Ltd.. All rights reserved.)
Published: 2024
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10. Neurologic and Neuropsychological Outcomes for Treatment of Unruptured Middle Cerebral Artery Aneurysms: Standard Pterional Versus Minipterional Approach in a Retrospective Single-Center Analysis.

Author: Di Bonaventura R, Albanese A, Brunasso L, Latour K, Siciliano L, Stifano V, Livi S, Sturiale CL, Iacopino DG, Maugeri R, Olivi A, and Marchese E
Subjects: Humans, Female, Male, Retrospective Studies, Middle Aged, Treatment Outcome, Aged, Neurosurgical Procedures methods, Adult, Neuropsychological Tests, Quality of Life, Microsurgery methods, Intracranial Aneurysm surgery, Postoperative Complications epidemiology, Postoperative Complications etiology
Abstract: Background: In accordance with technique advancement and minimal invasiveness surgical approaches, the minipterional has progressively replaced the standard pterional approach for treatment of unruptured middle cerebral artery (MCA) aneurysms. Nowadays, multimodal intraoperative resources including microDoppler and microflow probes, indocyanine green videoangiography, and neurophysiologic monitoring constitute a fundamental prerequisite for increasing the safety of the clipping procedure. Our study investigated and compared in a single-center experience the effect of the evolution of a minimally invasive and multimodal approach in unruptured MCA aneurysm surgery by measuring postoperative complication rate, recovery time, and long-term neuropsychological and functional outcomes., Methods: One hundred and thirty-one patients who underwent surgical treatment for unruptured MCA aneurysms at our institution were evaluated retrospectively. Patients' clinical, radiologic, and surgical reports were collected. Cognitive evaluation and quality of life were assessed through validated tests in telephone interviews. Patients who met the inclusion criteria were divided into 2 groups: "PT (pterional)" and "MPT (minipterional).", Results: Ninety-two patients were included in the analysis. A significant reduction of postoperative complication rates and new-onset postoperative seizures was recorded in the MPT group (P value = 0.006). Severe cognitive deficits were lower in the MPT group, although without a clear statistical correlation., Conclusions: Decreased complication rates, faster recovery time, and a trend toward better cognitive and functional performances were documented for the MPT group of patients. In our experience, the minipterional approach with multimodality-assisted microsurgery reduced neurologic complications and recovery time and improved long-term cognitive outcome and quality of life., (Copyright © 2024 Elsevier Inc. All rights reserved.)
Published: 2024
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11. Preoperative Angiographic Protocol for the Surgical Management of Spinal Dural Arteriovenous Fistulas: A Technical Nuance for Safe Minimally Invasive Surgery.

Author: Di Bonaventura R, Brunasso L, Sturiale CL, Valente I, Pedicelli A, Marchese E, Maugeri R, Iacopino DG, Olivi A, and Albanese A
Subjects: Humans, Male, Middle Aged, Female, Aged, Adult, Neurosurgical Procedures methods, Angiography methods, Microsurgery methods, Spinal Cord diagnostic imaging, Spinal Cord blood supply, Spinal Cord surgery, Central Nervous System Vascular Malformations surgery, Central Nervous System Vascular Malformations diagnostic imaging, Preoperative Care methods, Minimally Invasive Surgical Procedures methods
Abstract: Background: Interruption of the fistulous point is the goal of treatment of spinal dural arteriovenous fistulas (dAVFs). Microsurgery remains a highly efficient treatment in terms of complete occlusion with the lowest risk of recurrence rate. It is reported that the hardest step involves finding the fistulous site itself, potentially extending surgical access and time and increasing potential postoperative surgical-related complications. The accurate preoperative detection of the shunt and spinal level together is crucial for guiding optimal, fast, and safe microsurgical treatment., Methods: We describe a preoperative angiographic protocol for achieving a safe and simple resection of spinal dural arteriovenous fistulas based on a 6-year institutional experience of 42 patients who underwent minimally invasive procedures. Two illustrative cases are included to support the technical descriptions., Results: The suspected artery associated with the vascular malformation of interest is studied in our angiographic protocol through nonsubtracted selective acquisitions in lateral projection. The resulting frames are reconstructed with three-dimensional rotational angiography. The implementation of the preoperative angiographic protocol allowed 100% of intraoperative identification of the fistulous point in all cases with the use of a minimally invasive approach., Conclusions: Nowadays, neurosurgeons advocate for minimally invasive procedures and procedures with low morbidity risk for treatment of spinal dural arteriovenous fistulas. Our preoperative approach for accurate angiographic localization of the fistulous point through nonsubtracted and three-dimensional reconstructed angiography allowed us to achieve safe and definitive occlusion of the shunt., (Copyright © 2024 Elsevier Inc. All rights reserved.)
Published: 2024
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12. Preventing Ventricular Catheter Displacement and Infection with the "Catheter-Locking Device-Assisted" Technique: A Retrospective Study of 231 Patients.

Author: Piccirilli M, Scafa AK, Marchese E, Gallo M, and Santoro A
Subjects: Adult, Humans, Retrospective Studies, Cerebrospinal Fluid Shunts adverse effects, Catheters, Ventriculostomy adverse effects, Ventriculostomy methods, Drainage methods, Ventriculoperitoneal Shunt adverse effects, Hydrocephalus surgery, Hydrocephalus etiology
Abstract: Background: Inserting cerebrospinal fluid diversion devices such as external ventricular drains (EVDs) and ventriculoperitoneal shunts (VPSs) is a critical procedure. Unfortunately, complications such as catheter misplacement, dislocation, or infection can occur. Various surgical strategies aim to reduce these risks. One recent innovation is the "catheter-locking device-assisted" technique for EVD surgery. In this study, we examined its application in a larger group of cases encompassing both EVDs and VPSs over a 30-month period, with a focus on these complications., Methods: All adult patients who underwent a shunt procedure for noninfectious hydrocephalus at our institution from January 2021 to June 2023 were reviewed. We compared complications between those treated with the "standard" technique (subgroup A) and those managed with the "catheter-locking device-assisted" approach (subgroup B)., Results: In the EVD surgical group (initial procedures, n = 161), 6 patients (3.7%) required reoperation owing to the catheter misplacement caused by inadvertent migration of the ventricular catheter within the operating room ("early" migration), while 11 patients (6.8%) experienced unintentional postoperative dislodgement ("delayed" migration). Seven patients (4.3%) developed an EVD-related infection after an average duration of 7.4 days. None of these complications were observed in subgroup B patients (P < 0.05). Among VPS patients (n = 137), 4 (2.9%), all in subgroup A, required reoperation due to intraoperative migration of the catheter (P = 0.121); no other complications were identified., Conclusions: The "catheter-locking device-assisted" technique may significantly decrease the occurrence of the most common EVD complications and can also prove beneficial in VPS surgery. However, further investigation is necessary., (Copyright © 2023 The Author(s). Published by Elsevier Inc. All rights reserved.)
Published: 2024
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13. Comparison Between Intrasylvian and Intracerebral Hematoma Associated with Ruptured Middle Cerebral Artery Aneurysms: Clinical Implications, Technical Considerations, and Outcome Evaluation.

Author: Sturiale CL, Scerrati A, Ricciardi L, Rustemi O, Auricchio AM, Norri N, Piazza A, Ranieri F, Benato A, Tomatis A, Albanese A, Mangiola A, Di Egidio V, Zotta DC, Farneti M, Marchese E, Raco A, Volpin L, and Trevisi G
Subjects: Humans, Cerebral Hemorrhage complications, Cerebral Hemorrhage diagnostic imaging, Hematoma diagnostic imaging, Hematoma etiology, Hematoma surgery, Treatment Outcome, Retrospective Studies, Intracranial Aneurysm complications, Intracranial Aneurysm diagnostic imaging, Intracranial Aneurysm surgery, Aneurysm, Ruptured complications, Aneurysm, Ruptured diagnostic imaging, Aneurysm, Ruptured surgery, Subarachnoid Hemorrhage complications, Subarachnoid Hemorrhage diagnostic imaging, Subarachnoid Hemorrhage surgery
Abstract: Background: Subarachnoid hemorrhage (SAH) due to a middle cerebral artery (MCA) aneurysm rupture is often associated with an intracerebral hematoma (ICH) or intrasylvian hematoma (ISH)., Methods: We reviewed 163 patients with ruptured MCA aneurysms associated with pure SAH or SAH plus ICH or ISH. The patients were first dichotomized according to the presence of a hematoma (ICH or ISH). Next, we performed a subgroup analysis comparing ICH versus ISH to explore their relationship with the most relevant demographic, clinical, and angioarchitectural features., Results: Overall, 85 patients (52%) had a pure SAH, and 78 (48%) had presented with an associated ICH or ISH. No significant differences were observed in the demographics or angioarchitectural features between the 2 groups. However, the Fisher grade and Hunt-Hess score were higher for the patients with hematomas. A good outcome was observed in a higher percentage of patients with pure SAH compared with those with an associated hematoma (76% vs. 44%), although the mortality rates were comparable. Age, Hunt-Hess score, and treatment-related complications were the main outcome predictors on multivariate analysis. Patients with ICH appeared worse clinically compared with those with ISH. We also found that older age, a higher Hunt-Hess score, larger aneurysms, decompressive craniectomy, and treatment-related complications were associated with poor outcomes among the patients with an ISH, but not an ICH, which appeared, per se, as a more severe clinical condition., Conclusions: Our study has confirmed that age, Hunt-Hess score, and treatment-related complications influence the outcome of patients with ruptured MCA aneurysms. However, in the subgroup analysis of patients with SAH associated with an ICH or ISH, only the Hunt-Hess score at onset appeared as an independent predictor of the outcome., (Copyright © 2023 Elsevier Inc. All rights reserved.)
Published: 2023
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14. Decompressive hemicraniectomy in patients with malignant middle cerebral artery infarction: A real-world study.

Author: Pilato F, Pellegrino G, Calandrelli R, Broccolini A, Della Marca G, Frisullo G, Morosetti R, Profice P, Brunetti V, Capone F, D'Apolito G, Quinci V, Albanese A, Mangiola A, Marchese E, Pompucci A, and Di Lazzaro V
Subjects: Aged, Humans, Prognosis, Retrospective Studies, Treatment Outcome, Decompressive Craniectomy adverse effects, Decompressive Craniectomy methods, Infarction, Middle Cerebral Artery complications, Infarction, Middle Cerebral Artery diagnostic imaging, Infarction, Middle Cerebral Artery surgery
Abstract: Background: Malignant middle cerebral artery infarction (mMCA) is a devastating disease with rates of fatality as high as 80%. Decompressive hemicraniectomy (DHC) reduces mortality, but many survivors inevitably remain severely disabled. This study aimed to analyze patients with mMCA undergoing DHC or best medical treatment (BMT) baseline characteristics and factors linked to therapeutic choice and determinants of prognosis., Methods: We recorded clinical and radiological features of patients undergoing BMT or DHC. The two groups were compared for epidemiology, clinical presentation, neuroimaging, and prognosis. Regression analysis was performed to identify predictors of surgical treatment and outcome., Results: One hundred twenty-five patients were included (age 67.41 ± 1.39 yo; 65 M). Patients undergoing DHC (N = 57) were younger (DHC 55.71 ± 1.48 yo vs. BMT 77.22 ± 1.38) and had midline shift (DHC 96.5% (55/57) vs. BMT 35.3% (24/68), a larger volume of the affected hemisphere and reduced ventricles volume as compared to BMT. The chance of surgery depended on age (Exp(B) = 0.871, p < 0.001), clinical status at onset (NIHSS Exp(B) = 0.824, p = 0.030) and volume of the ventricle of the affected hemisphere (Exp(B) = 0.736, p = 0.006). Death rate during admission was significantly lower for DHC (DHC 15% (6/41) vs BMT 71.7% (38/53), Fisher's test = 30.234, p < 0.001)., Conclusion: Although DHC may cause prolonged hospitalization and long-term disabled patients, it is a lifesaving therapy that should be considered for selected patients with mMCA but perioperative complications and cost-utility should be considered. Patients and families should be correctly counseled about this therapeutic choice and its short- and long-term consequences., Competing Interests: Declaration of Competing Interest The Authors declare that there is no conflict of interest., (Copyright © 2022 Elsevier B.V. All rights reserved.)
Published: 2022
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15. Machine Learning-Based Prediction of 6-Month Postoperative Karnofsky Performance Status in Patients with Glioblastoma: Capturing the Real-Life Interaction of Multiple Clinical and Oncologic Factors.

Author: Della Pepa GM, Caccavella VM, Menna G, Ius T, Auricchio AM, Chiesa S, Gaudino S, Marchese E, and Olivi A
Subjects: Aged, Algorithms, Humans, Male, Middle Aged, Postoperative Period, Predictive Value of Tests, Brain Neoplasms surgery, Databases, Factual, Glioblastoma surgery, Machine Learning
Abstract: Objective: Ability to thrive after invasive and intensive treatment is an important parameter to assess in patients with glioblastoma multiforme (GBM). Karnofsky Performance Status (KPS) is used to identify those patients suitable for postoperative radiochemotherapy. The aim of the present study is to investigate whether machine learning (ML)-based models can reliably predict patients' KPS 6 months after surgery., Methods: A cohort of 416 patients undergoing surgery for a histopathologically confirmed GBM were collected from a multicentric database and split into a training and hold-out test set in an 80:20 ratio. Worsening of KPS at 6 months after surgery (compared with preoperative KPS) occurred in 138 patients (33.2%). Relevant preoperative, intraoperative, and immediately postoperative variables were selected by a recursive features selection algorithm (Boruta) and used to build 2 ML-based predictive models., Results: A random forest classifier and a random forest regressor were trained to predict 6 months postoperative KPS as a categorical (worsening vs. stable/improving) and continuous variables; they achieved, respectively, an area under the curve of 0.81 (95% confidence interval, 0.76-0.84) and a mean absolute error of 4.4 (95% confidence interval, 4.0-4.7). Leveraging the predictive value resulting from the combination of independent variables, the random forest classifier outperformed conventional statistics (area under the curve improvement of +21%)., Conclusions: Two robust ML-based prediction models were successfully trained and internally validated. Considerable effort remains to improve the interpretation of the results when these predictions are used in a patient-centered care context., (Copyright © 2021 Elsevier Inc. All rights reserved.)
Published: 2021
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16. Combined Use of Color Doppler Ultrasound and Contrast-Enhanced Ultrasound in the Intraoperative Armamentarium for Arteriovenous Malformation Surgery.

Author: Della Pepa GM, Di Bonaventura R, Latour K, Sturiale CL, Marchese E, Puca A, Sabatino G, and Albanese A
Subjects: Adult, Arteriovenous Fistula diagnostic imaging, Cerebral Angiography, Coloring Agents, Female, Fluorescein Angiography, Humans, Indocyanine Green, Intracranial Arteriovenous Malformations diagnostic imaging, Intraoperative Care methods, Male, Middle Aged, Multimodal Imaging methods, Rupture, Spontaneous, Ultrasonography methods, Arteriovenous Fistula surgery, Contrast Media, Intracranial Arteriovenous Malformations surgery, Ultrasonography, Doppler, Color methods
Abstract: Background: Safety and efficacy in surgical treatment of cerebral arteriovenous malformations (AVMs) are dictated by thorough understanding of angioarchitectural features, intraoperative identification of feeding vessels, and appreciation of surrounding eloquent areas. Our aim was to describe the preliminary results of combined application of color Doppler ultrasound (CDUS) and contrast-enhanced ultrasound (CEUS) in a consecutive surgical series of AVM. We pointed out the tool's efficacy in distinguishing feeding from bystander vessels and in identifying pattern of venous drainage. We examined its role as an adjunct for semiquantitative evaluation of the nidus inflow., Methods: We used combined CDUS and CEUS in patients surgically treated for cerebral AVMs. We adopted these techniques following a designed protocol to guide safer AVM resection as an adjunct to indocyanine green videoangiography. Intraoperative assessment by ultrasound was performed before, during, and following nidus resection., Results: Four surgically treated cerebral AVMs availed of the ultrasound protocol. Postoperative conventional angiography showed complete resection of the AVMs. CDUS and CEUS proved to be valuable adjunctive tools to indocyanine green videoangiography and micro-Doppler in properly navigating and discerning vascular structures, especially vessel feeders from bystanders. The protocol allows us to identify flow direction, estimate blood velocity within the nidus, and appreciate flow modifications following temporary clipping. Ultimately, it allows us to evaluate the degree of nidus deafferentation, residual flow, restoration of venous drainage and absence of arteriovenous shunts., Conclusions: The CDUS and CEUS protocol is safe and repeatable and works as real-time imaging, further supporting complete surgical resection of AVMs., (Copyright © 2020 Elsevier Inc. All rights reserved.)
Published: 2021
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17. Comparison Between Minipterional Craniotomy Associated With Focused Sylvian Fissure Opening and Standard Pterional Approach With Extended Sylvian Fissure Dissection for Treatment of Unruptured Middle Cerebral Artery Aneurysms.

Author: Di Bonaventura R, Sturiale CL, Latour K, Mazzucchi E, Marchese E, and Albanese A
Subjects: Adult, Aged, Female, Humans, Male, Middle Aged, Retrospective Studies, Treatment Outcome, Craniotomy methods, Dissection methods, Intracranial Aneurysm surgery, Middle Cerebral Artery surgery, Postoperative Complications epidemiology
Abstract: Background: In our institution, standard pterional craniotomy (PC) with an extended Sylvian fissure opening (ESFO) represented the standard approach for unruptured middle cerebral artery (MCA) aneurysm clipping until 2014, when we progressively started to prefer minipterional craniotomy (MPC) associated with a focused Sylvian fissure opening (FSFO). In the present study, we compared our results in terms of the efficacy of clipping and the rate of complications with these 2 different techniques., Methods: We included patients with small- and medium-size unruptured MCA aneurysms from January 2008 to December 2018 with follow-up of >12 months. The clinical and radiologic data were reviewed from the medical records. The outcomes were measured in terms of efficacy (aneurysmal exclusion rate) and safety (intracranial complication rate)., Results: Overall, 134 patients who had presented with unruptured MCA aneurysms <1.5 cm were treated at our institution from January 2007 to December 2018: PC and ESFO were used in 73 patients and MPC and FSFO in 61. The demographics and angioarchitectural features were comparable between the 2 groups, except for age, which was older in the FSFO group. The aneurysm exclusion rate was not different between the 2 groups. The intracranial complication rate was, overall, significantly lower in the FSFO group (P < 0.001), especially for the rate of postoperative seizures. Finally, the FSFO group had had shorter postoperative hospitalization and better short- and long-term clinical outcomes., Conclusions: The association between MPC and FSFO should represent the standard of treatment of unruptured MCA aneurysms in all referral cerebrovascular centers, allowing for the achievement of the same efficacy of standard PC with ESFO and minimizing the complications., (Copyright © 2020 Elsevier Inc. All rights reserved.)
Published: 2021
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18. Contrast enhanced ultrasound (CEUS) applications in neurosurgical and neurological settings - New scenarios for brain and spinal cord ultrasonography. A systematic review.

Author: Della Pepa GM, Menna G, Ius T, Di Bonaventura R, Altieri R, Marchese E, Olivi A, Sabatino G, and La Rocca G
Subjects: Brain diagnostic imaging, Contrast Media, Humans, Image Enhancement, Spinal Cord diagnostic imaging, Treatment Outcome, Brain Diseases diagnostic imaging, Neurosurgical Procedures methods, Spinal Cord Diseases diagnostic imaging, Ultrasonography, Interventional methods
Abstract: Contrast-enhanced ultrasound (CEUS) is a real-time, feasible technique. Both intraoperatively and bedside, it satisfies the need for serial assessment and easy performability. Initially employed in neuro-oncology, it has recently overcome this first application. We aimed to evaluate the literature and give a comprehensive view of its use in the fields listed below. A systematic review of all pertinent literature was performed via PubMed access according PRISMA P guidelines. Studies not involving human adults and not reporting original data were excluded. Cross-check of references of selected articles was performed to complete bibliographical research. 67 articles were then grouped by field of application: Oncology (26 articles) further subdivided in a) cranial tumors (23 articles) and b) spinal tumors (3 articles); Vascular (31 articles), divided in three sections: a) aneurysms, AVMs and AVFs surgery (6 articles), b) cerebral perfusion assessment and acute stroke patients management (15 articles), c) carotid plaques treatment (10 articles); TBI (2 articles); Pediatrics (4 articles); Peripheral nerve surgery (2 articles) and others (2 articles). CEUS versatility across the aforementioned areas was analyzed, underlining its complementarity to other well-settled imaging techniques. This review is focused on reporting CEUS advantages and disadvantages, suggesting a further broadening of the already numerous applications., (Copyright © 2020 Elsevier B.V. All rights reserved.)
Published: 2020
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19. Trans-sulcal versus trans-parenchymal approach in supratentorial cavernomas. A multicentric experience.

Author: La Rocca G, Ius T, Mazzucchi E, Simboli GA, Altieri R, Garbossa D, Acampora A, Auricchio AM, Vincitorio F, Cofano F, Vercelli G, Della Pepa GM, Pignotti F, Albanese A, Marchese E, and Sabatino G
Subjects: Adult, Craniotomy methods, Female, Humans, Male, Middle Aged, Retrospective Studies, Treatment Outcome, Central Nervous System Neoplasms surgery, Hemangioma, Cavernous, Central Nervous System surgery, Neurosurgical Procedures methods
Abstract: Objectives: Cavernous malformations (CM) are low-flow vascular lesions that can cause significant symptoms and neurological deficits. Different intraoperative surgical approaches have been developed. Aim of the present investigation is the comparison between the trans-sulcal approach (TS) and the trans-parenchymal neuronavigation-assisted approach (TPN) in a surgical series from two neurosurgical centers. The technique and clinical outcomes are discussed, with a specific focus on seizure outcome., Patients and Methods: Clinical and radiological data from two neurosurgical centers ("A. Gemelli" Hospital in Rome and A.O.U. Città della Salute e della Scienza in Turin) were retrospectively reviewed in order to evaluate the different outcome of TS and TPN approach for cavernous malformation treatment., Results: A total of 177 patients underwent surgical intervention for supratentorial CM, 130 patients with TPN approach and 47 with TS approach. TS approach was associated with higher rate of seizure in early post-operative period both in epileptic patients (p < 0,001) and in patients without history of seizures before surgery (p = 0,002). Moreover, length of incision (p < 0,001), area of craniotomy (p < 0,001) and corticectomy (p < 0,001) were bigger in TS than in TPN approach. Brain contusion (p < 0,001) and fluid collection (p < 0,001) were more likely to be discovered after TS approach., Conclusions: TPN is a valuable approach for resection of CM. Minor complications are significantly lower in TPN approach when compared with TS approach. In addition, it is associated with lower rate of early post-operative seizure and shorter length of stay., (Copyright © 2020 Elsevier B.V. All rights reserved.)
Published: 2020
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20. Exploring Key Challenges of Understanding the Pathogenesis of Kidney Disease in Bardet-Biedl Syndrome.

Author: Marchese E, Ruoppolo M, Perna A, Capasso G, and Zacchia M
Abstract: Bardet-Biedl syndrome (BBS) is a rare pleiotropic inherited disorder known as a ciliopathy. Kidney disease is a cardinal clinical feature; however, it is one of the less investigated traits. This study is a comprehensive analysis of the literature aiming to collect available information providing mechanistic insights into the pathogenesis of kidney disease by analyzing clinical and basic science studies focused on this issue. The analysis revealed that the syndrome is either clinically and genetically heterogenous, with 24 genes discovered to date, but with 3 genes ( BBS1 , BBS2 , and BBS10 ) accounting for almost 50% of diagnoses; genotype-phenotype correlation studies showed that patients with BBS1 mutations have a less severe renal phenotype than the other 2 most common loci; in addition, truncating rather than missense mutations are more likely to cause kidney disease. However, significant intrafamilial clinical variability has been described, with no clear explanation to date. In mice kidneys, Bbs genes have relative low expression levels, in contrast with other common affected organs, like the retina; surprisingly, Bbs1 is the only locus with basal overexpression in the kidney. In vitro studies indicate that signalling pathways involved in embryonic kidney development and repair are affected in the context of BBS depletion; in mice, kidney disease does not have a full penetrance; when present, it resembles human phenotype and shows an age-dependent progression. Data on the exact contribution of local versus systemic consequences of Bbs dysfunction are scanty and further investigations are required to get firm conclusions., (© 2020 International Society of Nephrology. Published by Elsevier Inc.)
Published: 2020
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21. 5-Aminolevulinic Acid False Positives in Cerebral Neuro-Oncology: Not All That Is Fluorescent Is Tumor. A Case-Based Update and Literature Review.

Author: La Rocca G, Sabatino G, Menna G, Altieri R, Ius T, Marchese E, Olivi A, Barresi V, and Della Pepa GM
Subjects: Brain Neoplasms diagnosis, Chemoradiotherapy, Adjuvant, Female, Glioma diagnosis, Glioma surgery, Humans, Intraoperative Care, Middle Aged, Necrosis, Neurosurgical Procedures, Oligodendroglioma diagnosis, Radiation Injuries pathology, Radiation Injuries surgery, Aminolevulinic Acid, Brain Neoplasms therapy, Diagnostic Errors, False Positive Reactions, Fluorescent Dyes, Neoplasm Recurrence, Local diagnosis, Oligodendroglioma therapy, Radiation Injuries diagnosis
Abstract: Background: One of the most valuable innovations in high-grade glioma surgery is 5-aminolevulinic acid (5-ALA). Fluorescence is a specific and sensitive indicator of metabolically active tumor tissue. In the published literature, the main focus has been placed on false-negative cases, with only a few articles addressing false positivity. The aim of the article was to highlight settings in which 5-ALA fluorescence does not necessarily mean tumor and to point out conditions in which intraoperative 5-ALA fluorescence has to be critically interpreted., Methods: Using PubMed, a review of pertinent literature was done to specifically investigate all conditions, including non-neoplastic and other metabolically active lesions, that can mimic high-grade gliomas and cause a misleading intraoperative diagnosis. In addition, an institutional case characterized by strong 5-ALA fluorescence in radionecrosis is presented., Results: Literature results were grouped in 2 main categories according to the field of application: oncologic setting (9 articles and 1 institutional case) and nononcologic settings (5 articles)., Conclusions: As reported, 5-ALA-induced fluorescence is not limited to glioma but is also evident in nonglioma and non-neoplastic conditions. Critical interpretation of intraoperative fluorescence is therefore mandatory in recurrences and in atypical cases that might hinder alternative diagnoses., (Copyright © 2020 Elsevier Inc. All rights reserved.)
Published: 2020
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22. Erratum to 'Contrast-Enhanced Ultrasonography and Color Doppler: Guided Intraoperative Embolization of Intracranial Highly Vascularized Tumors' [World Neurosurgery 128 (2019) 547-555].

Author: Della Pepa GM, Marchese E, Pedicelli A, Olivi A, Ricciardi L, Rapisarda A, Skrap B, Sabatino G, and La Rocca G
Published: 2019
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23. Contrast-Enhanced Ultrasonography and Color Doppler: Guided Intraoperative Embolization of Intracranial Highly Vascularized Tumors.

Author: Della Pappa GM, Marchese E, Pedicelli A, Olivi A, Ricciardi L, Rapisarda A, Skrap B, Sabatino G, and La Rocca G
Subjects: Brain Neoplasms diagnostic imaging, Contrast Media, Cranial Fossa, Posterior, Female, Hemangioblastoma diagnostic imaging, Humans, Middle Aged, Surgery, Computer-Assisted, Ultrasonography methods, Brain Neoplasms surgery, Embolization, Therapeutic methods, Hemangioblastoma surgery, Intraoperative Care methods, Neurosurgical Procedures methods, Ultrasonography, Doppler, Color methods
Abstract: Background: Preoperative embolization is often considered mandatory in highly vascularized brain tumors to contain blood loss. However, not all lesions are amenable to endovascular preoperative embolization. In the literature, cases of preoperative and intraoperative embolization are described only by arterial catheterization, whereas experiences of tumor embolization through direct puncture of the lesion are anecdotal; furthermore these cases lack an intraoperative control method to assess the effects of the embolizing procedure itself., Methods: We describe the association of contrast enhanced ultrasonography (CEUS) and color Doppler ultrasonography (CDUS) to perform intraoperative embolization in an illustrative case of a posterior cranial fossa hemangioblastoma not amenable to a preoperative endovascular procedure. The combination of CEUS and CDUS was tested as an option for the intraoperative devascularization of tumors in which preoperative embolization is considered risky or not possible., Results: The association of CEUS and CDUS provided real-time intraoperative data that directly guided the intraoperative embolization and provided reliable data about the hemodynamic effects produced after the direct injection of an embolizing agent. The technique offered a true real-time definition of the anatomic characteristics of the lesion and its relationships with the adjacent structures while distinguishing feeding from draining vessels., Conclusions: This technique has been proved to be a valuable tool in the surgical resection of highly vascularized tumors and in the treatment of intracranial and spinal vascular lesions and can be considered an option in those cases in which preoperative embolization is not possible. It is a feasible, modern, and cost-effective intraoperative imaging technique that allows identification of unexposed anatomic structures, hence minimizing surgical exposition and surgical manipulation., (Copyright © 2019 Elsevier Inc. All rights reserved.)
Published: 2019
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24. Lateral Supraorbital Versus Pterional Approach: Analysis of Surgical, Functional, and Patient-Oriented Outcomes.

Author: La Rocca G, Della Pepa GM, Sturiale CL, Sabatino G, Auricchio AM, Puca A, Olivi A, Marchese E, and Albanese A
Subjects: Computed Tomography Angiography, Female, Functional Laterality, Glasgow Outcome Scale, Humans, Magnetic Resonance Imaging, Male, Plastic Surgery Procedures, Retrospective Studies, Treatment Outcome, Craniotomy methods, Intracranial Aneurysm psychology, Intracranial Aneurysm surgery, Neurosurgical Procedures methods, Prefrontal Cortex surgery
Abstract: Background: Recently, the lateral supraorbital (LSO) keyhole variant of the standard pterional (PT) approach has been popularized for anterior skull base surgery, because it provides good anatomic exposition, reduced complications, and better aesthetic and functional results. However, these aspects have been formally compared only by a limited number of studies. We reviewed our experience with 50 consecutive anterior communicating artery (AComA) and A1/A2 aneurysms. Of these 50 patients, 25 had undergone the standard PT approach and 25, the LSO variant. We report the results in terms of exclusion of the aneurysm, postoperative complications, functional/masticatory outcomes, and aesthetic and patient satisfaction., Methods: From January 2014 to December 2015, 25 patients with unruptured AComA and A1/A2 aneurysms underwent the standard PT craniotomy. From January 2016 to March 2017, another 25 patients underwent the LSO technique., Results: No statistically significant differences were observed in the aneurysmal exclusion rate at angiographic follow-up or major complications. A statistically significant difference in the clinical outcome (Glasgow Outcome Scale) was evident only for the immediate postoperative time and was not significant during the follow-up period. The hospital stay was shorter in the LSO group. Minor complications, patient satisfaction, aesthetics, and functional and masticatory outcomes were significantly better statistically in the LSO group., Conclusions: The LSO approach demonstrated a lower rate of early clinical minor complications, with a reduction in hospitalization. The LSO approach provides better results for patient satisfaction, masticatory comfort, and cosmetic results. In our experience, the LSO approach is a safe and effective substitute to the standard PT craniotomy to treat unruptured AComA and A1/A2 aneurysms., (Copyright © 2018 Elsevier Inc. All rights reserved.)
Published: 2018
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25. Integration of Real-Time Intraoperative Contrast-Enhanced Ultrasound and Color Doppler Ultrasound in the Surgical Treatment of Spinal Cord Dural Arteriovenous Fistulas.

Author: Della Pepa GM, Sabatino G, Sturiale CL, Marchese E, Puca A, Olivi A, and Albanese A
Subjects: Adult, Arteriovenous Fistula diagnostic imaging, Central Nervous System Vascular Malformations diagnostic imaging, Contrast Media, Female, Humans, Spinal Cord diagnostic imaging, Spinal Cord Diseases diagnostic imaging, Ultrasonography, Doppler, Color, Arteriovenous Fistula surgery, Central Nervous System Vascular Malformations surgery, Spinal Cord surgery, Spinal Cord Diseases surgery
Abstract: Background: In the surgical treatment of spinal dural arteriovenous fistulas (DAVFs), intraoperative definition of anatomic characteristics of the DAVF and identification of the fistulous point is mandatory to effectively exclude the DAVF., Case Description: Intraoperative ultrasound and contrast-enhanced ultrasound integrated with color Doppler ultrasound was applied in the surgical setting for a cervical DAVF to identify the fistulous point and evaluate correct occlusion of the fistula., Conclusions: Integration of intraoperative ultrasound and contrast-enhanced ultrasound is a simple, cost-effective technique that provides an opportunity for real-time dynamic visualization of DAVF vascular patterns, identification of the fistulous point, and assessment of correct exclusion. Compared with other intraoperative tools, such as indocyanine green videoangiography, it allows the surgeon to visualize hidden anatomic and vascular structures, minimizing surgical manipulation and guiding the surgeon during resection., (Copyright © 2018 Elsevier Inc. All rights reserved.)
Published: 2018
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26. Electrocardiographic-Guided Technique for Placement of Ventriculoatrial Shunts: A Valid and Cost-Effective Technical Simplification.

Author: Della Pepa GM, Sabatino G, Peppucci E, Sturiale CL, Albanese A, Puca A, Olivi A, Marchese E, and Perotti V
Subjects: Adolescent, Adult, Aged, Aged, 80 and over, Catheterization, Central Venous economics, Catheterization, Central Venous instrumentation, Catheterization, Central Venous methods, Cerebrospinal Fluid Shunts instrumentation, Female, Humans, Male, Middle Aged, Surgery, Computer-Assisted instrumentation, Young Adult, Cerebral Ventricles surgery, Cerebrospinal Fluid Shunts economics, Cerebrospinal Fluid Shunts methods, Cost-Benefit Analysis, Electrocardiography economics, Electrocardiography methods, Heart Atria surgery, Hydrocephalus surgery, Surgery, Computer-Assisted economics, Surgery, Computer-Assisted methods
Abstract: Background: Ventriculoatrial (VA) shunt is a routine technique for the treatment of hydrocephalus. The correct position at the superior vena cava-right atrium junction is generally assessed by radiography. We present the first experience of an alternative, nonradiographic technique to assess the distal end of the VA shunts through an electrocardiographic (EKG) method. The technique has developed from the large experience of central venous catheters (CVC) worldwide; the EKG-guided method is a common and validated alternative to standard radiologic control of the location of the tip of any CVC., Methods: Five consecutive patients underwent VA shunt with venous catheter positioned with the EKG-guided technique. The position of the catheter tip was verified by standard chest radiography., Results: Four men and 1 woman (mean age, 45.4 years) underwent VA shunt for hydrocephalus with the EKG-guided technique. The side of internal jugular vein puncture was the right side in 4 cases and the left side in 1 case. As confirmed by radiography, all VA shunt tips were located within the correct range. There was no radiologic evidence of procedure-related complication or catheters that had to be replaced., Conclusions: The EKG-guided technique for VA shunts is as accurate as fluoroscopy, but simpler, more readily available, less expensive, safer, and more cost effective. It reduces the need of radiography and radiologic exposition for both patients and operators. The EKG method may be a valid and cost-effective alternative to standard radiologic control in VA shunts, as for any central venous access device, and could become the preferential method for confirming tip position during VA shunt surgery., (Copyright © 2017 Elsevier Inc. All rights reserved.)
Published: 2018
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27. Endovascular Treatment of the Posterior Cerebral Artery Aneurysms: Single-Center Experience and a Systematic Review.

Author: Sturiale CL, De Waure C, Della Pepa GM, Calabrò GE, Albanese A, D'Argento F, Fernandez E, Olivi A, Puca A, Pedicelli A, and Marchese E
Subjects: Brain Ischemia etiology, Embolization, Therapeutic adverse effects, Endovascular Procedures adverse effects, Humans, Postoperative Complications etiology, Aneurysm, Ruptured therapy, Brain Ischemia epidemiology, Embolization, Therapeutic statistics & numerical data, Endovascular Procedures statistics & numerical data, Intracranial Aneurysm therapy, Posterior Cerebral Artery, Postoperative Complications epidemiology
Abstract: Background: Endovascular treatment of posterior cerebral artery aneurysms is challenging because of the particular features of posterior circulation vessels. We performed a systematic review of the literature, to assess safety and efficacy associated to their endovascular treatment., Methods: Through a literature search, we identified 20 studies that met our inclusion criteria. We also performed a retrospective analysis of patients treated at our institution during the last 10 years. Demographics, angiographic features, clinical presentation, and outcome were extracted from each study. Data were combined using a random effects model and heterogeneity was assessed by I(2)., Results: We retrieved 7 patients from our institutional series and 246 from the literature. Overall, 253/259 patients/aneurysms were included in this study. A selective coiling was performed in 27% of cases, a stent-assisted coiling in 2%, and a parent artery occlusion in 62%. Immediate complete/near-complete occlusion was obtained in 96% of cases and maintained in 90% at follow-up. No differences were observed between ruptured and unruptured aneurysms. Ischemic complications were reported in 15% of cases, although the most frequent was a hemianopsia in 7%; a hemiparesis was reported in only 2% of cases. Mortality was overall 1%. Ischemic complications were more frequent among patients who underwent nonselective treatment (P < 0.01)., Conclusions: Endovascular treatment of posterior cerebral artery aneurysms is associated with increased degree of occlusion and low recurrence rate. However, a parent artery occlusion implies complications, even although most of them are minor events such as hemianopsia., (Copyright © 2016 Elsevier Inc. All rights reserved.)
Published: 2016
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28. Are Breast Cancer Outcomes Compromised by General Surgical Resident Participation in the Operation?

Author: Tsigonis AM, Landercasper J, Al-Hamadani M, Linebarger JH, Vang CA, Johnson JM, Marchese E, Marcou KA, and Hudak JM
Subjects: Adult, Aged, Aged, 80 and over, Female, Humans, Middle Aged, Retrospective Studies, Treatment Outcome, Young Adult, Breast Neoplasms surgery, General Surgery education, Internship and Residency
Abstract: Objective: The effect of surgery resident participation on breast cancer recurrence has not been previously reported. The objectives of this study were to determine if resident participation was associated with either immediate postoperative or long-term breast cancer outcomes., Design: We retrospectively reviewed a prospectively collected breast center database to identify all patients with breast cancer undergoing surgery in a single center during a 9-year period ending 1 January 2010. Patients were divided into 2 groups based on whether surgery residents completed more than 50% of the critical portions of the case (Resident group) or not. The outcomes of operation length, reoperative rates, morbidity, and the long-term outcomes of cancer recurrence were compared by group. Comparisons of immediate postoperative outcomes were made with chi-square and Fisher exact tests. Comparisons of operation length were analyzed by Wilcoxon rank-sum testing. Survival analyses were calculated using the Kaplan-Meier method with log-rank comparison. Multivariate analysis with Cox regression was also performed., Setting: The study occurred at a community-based hospital that has an accredited general surgery training program., Participants: In all, 1107 consecutive patients with stage 0-3 breast cancer undergoing breast cancer operations were included., Results: Median age of patients was 64 years (range: 24-97). Median and longest follow-up were 5.5 and 12.5 years, respectively. Initial operation was breast conserving in 796 (72%) and mastectomy in 311 (28%). Of the 1107 patients, 887 (80.1%) had resident participation. The Resident group was associated with longer operative times. We identified no differences in operative morbidity, reoperations, overall survival, disease-free survival, or local-regional recurrence in the Resident and No Resident groups., Conclusions: Resident involvement in breast cancer operations was associated with longer operative times but did not affect any other perioperative or cancer outcome in our institution. This information can be used to reassure program directors, attending surgeons, and patients if they have questions or concerns about the safety or effectiveness of cancer surgery when there is surgical resident participation., (Copyright © 2015 Association of Program Directors in Surgery. Published by Elsevier Inc. All rights reserved.)
Published: 2015
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29. Diagnosis and management of dural arteriovenous fistulas: a 10 years single-center experience.

Author: Signorelli F, Della Pepa GM, Sabatino G, Marchese E, Maira G, Puca A, and Albanese A
Subjects: Adult, Aged, Aged, 80 and over, Central Nervous System Vascular Malformations complications, Central Nervous System Vascular Malformations surgery, Cerebral Hemorrhage etiology, Cerebral Hemorrhage therapy, Embolization, Therapeutic adverse effects, Female, Humans, Male, Middle Aged, Neurosurgical Procedures adverse effects, Retrospective Studies, Time Factors, Treatment Outcome, Central Nervous System Vascular Malformations diagnosis, Central Nervous System Vascular Malformations therapy, Embolization, Therapeutic methods, Neurosurgical Procedures methods
Abstract: Objectives: Dural arteriovenous fistulas (DAVFs) are a challenging condition in vascular neurosurgery. Disease natural history and its management is still debated. In the present paper we report our center series on DAVFs over a period of 10 years. Our data were compared with relevant literature., Patient and Methods: Our series includes 45 cases: 14 cavernous sinus, 11 transverse-sigmoid, 8 patients tentorial, 6 anterior cranial fossa, 5 patients spinal, 1 patient foramen magnum., Results and Conclusions: DVAFs distribution, clinical presentation and hemorrhagic risk are discussed. Cavernous sinus DAVFs are the most common site in our series. Other locations in order of frequency are transverse-sigmoid sinus, tentorial, anterior cranial fossa, spinal and foramen magnum. The majority of patients presented with non-aggressive symptoms. 18% presented with intracranial hemorrhage: all the hemorrhages occurred in high-grade DAVFs. For most patients, endovascular treatment, transarterial or transvenous, was the first option. Surgery was performed for the anterior cranial fossa DAVFs and other complex lesions draining mostly transverse-sigmoid sinus and tentorium. In 7% of cases a combination of endovascular+surgical treatment was used. Our series has been carefully analyzed in comparison 'side by side' with most relevant literature on DVAFs, focusing particularly on management strategies, therapeutic options and risks related to treatment., (Copyright © 2014 Elsevier B.V. All rights reserved.)
Published: 2015
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30. Protective effect of external ventricular drainage on cerebral vasospasm. A retrospective study on aneurysmal SAH treated endovascularly.

Author: Della Pepa GM, Scerrati A, Albanese A, Marchese E, Maira G, and Sabatino G
Subjects: Female, Humans, Male, Middle Aged, Protective Factors, Retrospective Studies, Treatment Outcome, Drainage methods, Endovascular Procedures adverse effects, Hydrocephalus surgery, Postoperative Complications prevention & control, Subarachnoid Hemorrhage surgery, Vasospasm, Intracranial prevention & control, Ventriculostomy methods
Abstract: Objective: Cerebral vasospasm (VS) is one of the factors that can most significantly worsen the prognosis after aneurysmal subarachnoid hemorrhage (SAH). A substantial body of evidence supports the idea that CSF diversion could prevent VS, even if this issue is still much debated. External ventricular drainage (EVD) is the recommended procedure for post-hemorrhagic hydrocephalus. In this study we analyzed whether EVD, placed for acute hydrocephalus, is effective in reducing the incidence of clinical and radiological cerebral vasospasm in patients who underwent endovascular treatment for aneurysmal SAH., Patients and Methods: We retrospectively studied the incidence of radiologically confirmed VS in 141 patients treated endovascularly for aneurysmal SAH: 80 underwent EVD for hydrocephalus, 61 did not undergo EVD., Results: VS occurred in 8.75% of cases (7 patients) in the first groups, while in 22.95% (14 patients) in the second group. In addition, patients not treated with EVD display a prevalence of VS in lower Fisher grades compared to the other group., Conclusion: Our data indicate that CSF drainage reduces the risk of vasospasms in patients with endovascular treatment for aneurysmal SAH., (Copyright © 2014 Elsevier B.V. All rights reserved.)
Published: 2014
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31. Indocyanine green video-angiography in neurosurgery: a glance beyond vascular applications.

Author: Scerrati A, Della Pepa GM, Conforti G, Sabatino G, Puca A, Albanese A, Maira G, Marchese E, and Esposito G
Subjects: Humans, Cerebral Angiography methods, Coloring Agents, Indocyanine Green, Monitoring, Intraoperative methods, Neurosurgical Procedures methods
Abstract: Objective: Indocyanine green video angiography (ICG-VA) is a non invasive, easy to use and a very useful tool for various neurosurgical procedures. Initially introduced in vascular neurosurgery since 2003, it's applications have broadened over time, both in vascular applications and in other neurosurgical fields. The objective of our study is to review all published literature about ICG-VA, cataloguing its different applications., Methods: A systematic review of all pertinent literature articles published from January 2003 to May 2014 using Pubmed access was performed using pertinent keywords; cross check of references of selected articles was performed in order to complete bibliographical research. Results of research were grouped by pathology., Results and Conclusions: The paper systematically analyses ICG-VA different applications in neurosurgery, from vascular neurosurgery to tumor resection and endoscopic applications, focusing on reported advantages and disadvantages, and discussing future perspectives., (Copyright © 2014 Elsevier B.V. All rights reserved.)
Published: 2014
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32. Galea-pericranium dural closure: can we safely avoid sealants?

Author: Giovanni S, Della Pepa GM, La Rocca G, Lofrese G, Albanese A, Maria G, and Marchese E
Subjects: Adolescent, Adult, Aged, Aged, 80 and over, Craniotomy methods, Female, Humans, Male, Middle Aged, Treatment Outcome, Young Adult, Dura Mater surgery, Neurosurgical Procedures, Postoperative Complications prevention & control, Tissue Adhesives therapeutic use
Abstract: Objective: Dural closure is one of the most critical steps in neurosurgical procedures as it prevents many common postoperative complications. Methods of dural closure include the use of allogenic, autogenic, xenogenic, absorbable or synthetic materials together with sealant/glues or hemostatic compounds. Most common autogenic graft is galea-pericranium. This study aims to demonstrate how the intrinsic properties of the galea-pericranium make effectively useless the application of any glue in order to ensure the watertight integrity of the graft., Patients and Methods: 276 cases were included in the study. Postoperative dural-closure related complication in patients subjected to duraplasty were analysed in three groups undergoing different duraplasty techniques: galea-pericranium graft without sealants, galea-pericranium graft plus sealant, non-autologous dural patch plus sealant., Results: No statistically significant differences between the three groups were observed in terms of subcutaneous fluid collection rate, CSF fistulas, brain abscesses, subdural empyemas, wound dehiscence, radiotherapic sequelae., Conclusions: Our study shows that galea-pericranium alone (without sealants) is comparable to other duraplasty techniques that involve the use of sealants or of non-autologous pathches in terms of long term postoperative results., (Copyright © 2014 Elsevier B.V. All rights reserved.)
Published: 2014
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33. Autologous dural substitutes: a prospective study.

Author: Sabatino G, Della Pepa GM, Bianchi F, Capone G, Rigante L, Albanese A, Maira G, and Marchese E
Subjects: Adolescent, Adult, Aged, Aged, 80 and over, Cohort Studies, Craniotomy methods, Female, Humans, Male, Middle Aged, Prospective Studies, Treatment Outcome, Young Adult, Brain Tissue Transplantation methods, Dura Mater transplantation, Transplantation, Autologous economics, Transplantation, Autologous methods
Abstract: Objective: Duraplasty can be performed both by means of autologous tissues (such as galea-pericranium, temporal muscle, fascia lata) or by commercially available dural patches. Nowadays many neurosurgeons consider galea-pericranium duraplasty time-consuming, technically demanding or not adequate, thus dural surrogates are increasingly popular. In this prospective research we compared duraplasty using autologous galea-pericranium vs. dural patches in terms of postoperative long term results, ease/time required and costs., Patients and Methods: Research has been designed as prospective cohort study, that included 185 patients undergoing supratentorial elective neurosurgery with galea-pericranium or non-autologous duraplasty (minimum follow-up 12 months). Variables taken into account were: wound infection, CSF fistula, subcutaneous CSF collection, bone flap osteitis, brain abscess, empyema and tardive wound dehiscence (particularly after postoperative radiotherapy). Time for galea-pericranium collection, size of galea-pericranium harvest and dural defects were recorded in each case. Costs for non-autologous duroplasty were calculated., Results: No statistically significant differences were evident in long term postoperative results between the two groups. Mean time of galea-pericranium collection is less than 2min and enough galea-pericranium can be harvested in supratentorial approach to cover almost any dural defect. The only difference between the two groups is costs: an average of 268.7€/patient spent just for duraplasty. This figure is surely substantial if considered for the entire amount of surgeries performed in a department., Conclusions: Considering that in our study long term results are equivalent, that galea-pericranium duraplasty is feasible and rapid, our indications are in favor of saving a considerable amount of money since an ideal autologous dural substitute is available and "free"., (Copyright © 2013 Elsevier B.V. All rights reserved.)
Published: 2014
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34. Relevance of bleeding pattern on clinical appearance and outcome in patients with hemorrhagic brain arteriovenous malformations.

Author: Sturiale CL, Puca A, Calandrelli R, D'Arrigo S, Albanese A, Marchese E, Alexandre A, Colosimo C, and Maira G
Subjects: Adult, Cerebral Angiography, Cerebral Ventricles pathology, Female, Glasgow Coma Scale, Hemorrhage, Humans, Intracranial Arteriovenous Malformations complications, Intracranial Hemorrhages etiology, Male, Microsurgery, Middle Aged, Multivariate Analysis, Neurologic Examination, Prognosis, Socioeconomic Factors, Subarachnoid Hemorrhage etiology, Tomography, X-Ray Computed, Treatment Outcome, Intracranial Arteriovenous Malformations blood, Intracranial Arteriovenous Malformations therapy, Intracranial Hemorrhages blood, Intracranial Hemorrhages therapy
Abstract: Although several descriptions of the angioarchitectural features of brain arteriovenous malformations (AVMs) associated with higher hemorrhagic risk have been reported, the prognostic value of the different bleeding patterns still needs to be elucidated. This study evaluated the influence on clinical appearance and outcome of the parenchymal and non-parenchymal (subarachnoid hemorrhage-SAH-and intraventricular hemorrhage-IVH) bleedings associated with ruptured AVMs. Clinical records and neuroradiological examinations of 30 patients with hemorrhagic AVMs were reviewed in order to identify their angioarchitectural features and the associated bleeding pattern. These data along with demographic characteristics and treatment modality were dichotomized and their relationship with clinical status at admission and follow-up was tested. IVH as well as parenchymal hematomas larger than 20 cm(3) appeared associated with a severe clinical status at admission, whereas SAH involving basal cisterns was significantly associated with unfavorable outcome. Age, sex and angioarchitectural features did not show significant association with the severity of the prognosis. However, none of these bleeding patterns appeared as an independent risk factor of poor outcome at multivariate analysis. In conclusion, our data emphasized the possibility that non-parenchymal bleeding may worsen the outcome of patients with hemorrhagic AVMs., (Copyright © 2012 Elsevier B.V. All rights reserved.)
Published: 2013
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35. Differential decrease of copper content and of copper binding to superoxide dismutase in liver, heart and brain of copper-deficient rats.

Author: Rossi L, Ciriolo MR, Marchese E, De Martino A, Giorgi M, and Rotilio G
Subjects: Animals, Catalase metabolism, Ceruloplasmin metabolism, Electron Spin Resonance Spectroscopy, Glutathione Peroxidase metabolism, Male, Protein Processing, Post-Translational, Rats, Rats, Wistar, Selenium pharmacology, Brain metabolism, Copper deficiency, Copper metabolism, Liver metabolism, Myocardium metabolism, Superoxide Dismutase metabolism
Abstract: Dietary copper-deficiency in rats produced a organ-specific decrease of copper content. This was paralleled by a decrease of the activity of the copper-enzyme superoxide dismutase. In liver such a decrease is partially due to the existence of an apo-form of superoxide dismutase, which can be reactivated by addition of exogenous copper to tissue extracts. These results demonstrate in vivo that superoxide dismutase is post-translationally modulated by copper in higher vertebrates as previously found for yeast and mammalian cells in culture.
Published: 1994
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36. Separation by cation-exchange high-performance liquid chromatography of three forms of Chinese hamster ovary cell-derived recombinant human interleukin-2.

Author: Marchese E, Vita N, Maureaud T, and Ferrara P
Subjects: Animals, Cell Line, Chromatography, High Pressure Liquid, Chromatography, Ion Exchange, Cricetinae, Cricetulus, Electrophoresis, Polyacrylamide Gel, Female, Mice, Recombinant Proteins isolation & purification, Interleukin-2 isolation & purification
Abstract: Purified recombinant (r) interleukin 2 (IL-2) produced by a transformed Chinese hamster ovary cell line shows a single peak when analysed by reversed-phase high-performance liquid chromatography, but it can be resolved into three forms by sodium dodecyl sulphate polyacrylamide gel electrophoresis. These three forms were successfully isolated by narrow-bore ion-exchange chromatography through optimization of the elution conditions. The addition of n-propanol as an organic modifier to the mobile phase proved to be essential for the recovery of the protein from the column in a yield of 90% or better based on protein quantification and biological activity determination. This chromatographic method was used for the purification of these three rIL-2 forms which represent variable glycosylation of a single polypeptide chain. A comparison of the biological activities using the murine CTLL-2 cell proliferation assay showed that the specific activities of the three forms are similar.
Published: 1990
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