1. Congenital multifocal rhabdoid tumor: a case with peculiar biological behavior and different response to treatment according to location (central nervous system and kidney).
- Author
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Pio L, Milanaccio C, Mascelli S, Raso A, Nozza P, Sementa AR, Cama A, Buffa P, Avanzini S, Vannati M, Capra V, Lanino E, Rossi A, Morana G, Magnano GM, Severino M, and Garrè ML
- Subjects
- Brain Neoplasms congenital, Brain Neoplasms genetics, Brain Neoplasms pathology, Cerebellum diagnostic imaging, Cerebellum pathology, Chromosomal Proteins, Non-Histone genetics, Codon, Nonsense genetics, Combined Modality Therapy, DNA-Binding Proteins genetics, Humans, Infant, Kidney Neoplasms congenital, Kidney Neoplasms genetics, Kidney Neoplasms pathology, Male, Radiography, Rhabdoid Tumor congenital, Rhabdoid Tumor genetics, Rhabdoid Tumor pathology, SMARCB1 Protein, Teratoma congenital, Teratoma genetics, Teratoma pathology, Transcription Factors genetics, Antineoplastic Agents therapeutic use, Antineoplastic Combined Chemotherapy Protocols therapeutic use, Brain Neoplasms therapy, Kidney Neoplasms therapy, Rhabdoid Tumor therapy, Teratoma therapy
- Abstract
Atypical teratoid/rhabdoid tumor (AT/RT) of the central nervous system and malignant rhabdoid tumor of the kidney (MRTK) may present with different responses to chemotherapy and outcomes. We describe the case of an infant with multifocal rhabdoid tumor with different behavior and response to treatment, depending on the anatomic site., (Copyright © 2014 Elsevier Inc. All rights reserved.)
- Published
- 2014
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