11 results on '"M Bidet"'
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2. Métrorragies pubertaires
- Author
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M. Bidet
- Published
- 2018
- Full Text
- View/download PDF
3. Vulvites et vulvovaginites prépubertaires
- Author
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M. Bidet
- Published
- 2018
- Full Text
- View/download PDF
4. Hémorragies génitales prépubertaires
- Author
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M. Bidet
- Published
- 2018
- Full Text
- View/download PDF
5. Position statement on the diagnosis and management of premature/primary ovarian insufficiency (except Turner Syndrome).
- Author
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Christin-Maitre S, Givony M, Albarel F, Bachelot A, Bidet M, Blanc JV, Bouvattier C, Brac de la Perrière A, Catteau-Jonard S, Chevalier N, Carel JC, Coutant R, Donadille B, Duranteau L, El-Khattabi L, Hugon-Rodin J, Houang M, Grynberg M, Kerlan V, Leger J, Misrahi M, Pienkowski C, Plu-Bureau G, Polak M, Reynaud R, Siffroi JP, Sonigo C, Touraine P, and Zenaty D
- Subjects
- Adult, Anti-Mullerian Hormone, Female, Follicle Stimulating Hormone, Fragile X Mental Retardation Protein, France, Hormone Replacement Therapy, Humans, Primary Ovarian Insufficiency diagnosis, Primary Ovarian Insufficiency therapy
- Abstract
Premature ovarian insufficiency (POI) is a rare pathology affecting 1-2% of under-40 year-old women, 1 in 1000 under-30 year-olds and 1 in 10,000 under-20 year-olds. There are multiple etiologies, which can be classified as primary (chromosomal, genetic, auto-immune) and secondary or iatrogenic (surgical, or secondary to chemotherapy and/or radiotherapy). Despite important progress in genetics, more than 60% of cases of primary POI still have no identifiable etiology; these cases are known as idiopathic POI. POI is defined by the association of 1 clinical and 1 biological criterion: primary or secondary amenorrhea or spaniomenorrhea of>4 months with onset before 40 year of age, and elevated follicle-stimulating hormone (FSH)>25IU/L on 2 assays at>4 weeks' interval. Estradiol level is low, and anti-Müllerian hormone (AMH) levels have usually collapsed. Initial etiological work-up comprises auto-immune assessment, karyotype, FMR1 premutation screening and gene-panel study. If all of these are normal, the patient and parents may be offered genome-wide analysis under the "France Génomique" project. The term ovarian insufficiency suggests that the dysfunction is not necessarily definitive. In some cases, ovarian function may fluctuate, and spontaneous pregnancy is possible in around 6% of cases. In confirmed POI, hormone replacement therapy is to be recommended at least up to the physiological menopause age of 51 years. Management in a rare diseases center may be proposed., (Copyright © 2021. Published by Elsevier Masson SAS.)
- Published
- 2021
- Full Text
- View/download PDF
6. Surgery is not superior to dilation for the management of vaginal agenesis in Mayer-Rokitansky-Küster-Hauser syndrome: a multicenter comparative observational study in 131 patients.
- Author
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Cheikhelard A, Bidet M, Baptiste A, Viaud M, Fagot C, Khen-Dunlop N, Louis-Sylvestre C, Sarnacki S, Touraine P, Elie C, Aigrain Y, and Polak M
- Subjects
- Adult, Dyspareunia, Female, Humans, Quality of Life, Plastic Surgery Procedures, Sexual Health, Treatment Outcome, Young Adult, 46, XX Disorders of Sex Development therapy, Congenital Abnormalities therapy, Dilatation methods, Gynecologic Surgical Procedures methods, Mullerian Ducts abnormalities, Vagina abnormalities
- Abstract
Background: Vaginal agenesis in Mayer-Rokitansky-Küster-Hauser syndrome can be managed either by various surgeries or dilation. The choice still depends on surgeon's preferences rather than on quality comparative studies and validated protocols., Objective: We sought to compare dilation and surgical management of vaginal agenesis in Mayer-Rokitansky-Küster-Hauser syndrome, in terms of quality of life, anatomical results, and complications in a large multicenter population., Study Design: Our multicenter study included 131 patients >18 years, at least 1 year after completing vaginal agenesis management. All had an independent gynecological evaluation including a standardized pelvic exam, and completed the World Health Organization Quality of Life instrument (general quality of life) as well as the Female Sexual Function Index and Female Sexual Distress Scale-Revised (sexual quality of life) scales. Groups were: surgery (N = 84), dilation therapy (N = 26), and intercourse (N = 20). One patient was secondarily excluded because of incomplete surgical data. For statistics, data were compared using analysis of variance, Student, Kruskal-Wallis, Wilcoxon, and Student exact test., Results: Mean age was 26.5 ± 5.5 years at inclusion. In all groups, World Health Organization Quality of Life scores were not different between patients and the general population except for lower psychosocial health and social relationship scores (which were not different between groups). Global Female Sexual Function Index scores were significantly lower in the surgery and dilation therapy groups (median 26 range [2.8-34.8] and 24.7 [2.6-34.4], respectively) than the intercourse group (30.2 [7.8-34.8], P = .044), which had a higher score only in the satisfaction dimension (P = .004). However, the scores in the other dimensions of Female Sexual Function Index were not different between groups. The Female Sexual Distress Scale-Revised median scores were, respectively, 17 [0-52], 20 [0-47], and 10 [10-40] in the surgery, dilation therapy, and intercourse groups (P = .38), with sexual distress in 71% of patients. Median vaginal depth was shorter in dilatation therapy group (9.6 cm [5.5-12]) compared to surgery group (11 cm [6-15]) and intercourse group (11 cm [6-12.5]) (P = .039), but remained within normal ranges. One bias in the surgery group was the high number of sigmoid vaginoplasties (57/84, 68%), but no differences were observed between surgeries. Only 4 patients achieved vaginas <6.5 cm. Delay between management and first intercourse was 6 months (not significant). Seventy patients (53%) had dyspareunia (not significant), and 17 patients all from the surgery group had an abnormal pelvic exam. In the surgery group, 34 patients (40.5%) had complications, requiring 20 secondary surgeries in 17 patients, and 35 (42%) needed postoperative dilation. In the dilation therapy group, 13 (50%) needed maintenance dilation., Conclusion: Surgery is not superior to therapeutic or intercourse dilation, bears complications, and should therefore be only a second-line treatment. Psychological counseling is mandatory at diagnosis and during therapeutic management., (Copyright © 2018 Elsevier Inc. All rights reserved.)
- Published
- 2018
- Full Text
- View/download PDF
7. Children and screens: Groupe de Pédiatrie Générale (Société française de pédiatrie) guidelines for pediatricians and families.
- Author
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Picherot G, Cheymol J, Assathiany R, Barthet-Derrien MS, Bidet-Emeriau M, Blocquaux S, Carbajal R, Caron FM, Gerard O, Hinterman M, Houde O, Jollivet C, Le Heuzey MF, Mielle A, Ogrizek M, Rocher B, Samson B, Ronziere V, and Foucaud P
- Subjects
- Adolescent, Child, Child, Preschool, Humans, Internet, Parents, Pediatrics, Microcomputers, Television
- Abstract
The Groupe de Pédiatrie Générale (General Pediatrics Group), a member of the Société française de pédiatrie (French Pediatrics Society), has proposed guidelines for families and doctors regarding children's use of digital screens. A number of guidelines have already been published, in particular by the French Academy of Sciences in 2013 and the American Academy of Pediatrics in 2016. These new guidelines were preceded by an investigation into the location of digital screen use by young children in France, a survey of medical concerns on the misuse of digital devices, and a review of their documented benefits. The Conseil Supérieur de l'Audiovisuel (Higher Council on Audiovisual Technology) and the Union Nationale de Associations Familiales (National Union of Family Associations) have taken part in the preparation of this document. Five simple messages are proposed: understanding without demonizing; screen use in common living areas, but not in bedrooms; preserve time with no digital devices (morning, meals, sleep, etc.); provide parental guidance for screen use; and prevent social isolation., (Copyright © 2018 Elsevier Masson SAS. All rights reserved.)
- Published
- 2018
- Full Text
- View/download PDF
8. [Puberty and cancer].
- Author
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Bidet M
- Subjects
- Adolescent, Child, Cryopreservation, Female, Gonads drug effects, Humans, Male, Ovary drug effects, Puberty, Spermatozoa, Antineoplastic Agents adverse effects, Fertility Preservation, Neoplasms therapy, Radiotherapy adverse effects
- Published
- 2015
- Full Text
- View/download PDF
9. Mouse myodulin, a new potential angiogenic factor, functionally expressed in yeast.
- Author
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Pisani DF, Rivoyre MD, Ruel L, Bonino F, Bidet M, Dechesne CA, and Mus-Veteau I
- Subjects
- Angiogenesis Inducing Agents isolation & purification, Animals, Cell Line, Cell Membrane metabolism, Cell Movement, Coculture Techniques, Endothelial Cells cytology, Endothelial Cells metabolism, Liposomes chemistry, Liposomes metabolism, Membrane Proteins genetics, Membrane Proteins isolation & purification, Mice, Muscle Proteins genetics, Muscle Proteins isolation & purification, Recombinant Proteins genetics, Recombinant Proteins isolation & purification, Recombinant Proteins metabolism, Saccharomyces cerevisiae cytology, Saccharomyces cerevisiae genetics, Angiogenesis Inducing Agents metabolism, Membrane Proteins metabolism, Muscle Proteins metabolism, Saccharomyces cerevisiae metabolism
- Abstract
Myodulin is a new integral membrane protein down-regulated in skeletal muscle atrophy. A first characterization suggested that myodulin could be a skeletal muscle angiogenic factor operating through direct cell-to-cell interactions. Here, we show that mouse myodulin can be expressed at the plasma membrane of Saccharomyces cerevisiae and purified. Co-culture experiments of myoblasts and cardiac vascular endothelial cells reveal that myodulin, either presented in yeast membranes or in liposomes after purification, increases the invasive potential of endothelial cells with a similar efficiency as when over-expressed in skeletal muscle cells. Functional essays using myodulin expressed in yeast bring new information about the myodulin functional mechanism, suggesting that one or several muscle cell components could be necessary for myodulin to increase the invasive potential of endothelial cells. The yield of purified myodulin should allow structure-function relationships studies for a better understanding of myodulin functional mechanisms.
- Published
- 2005
- Full Text
- View/download PDF
10. Calcium transport in rabbit distal cells.
- Author
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Poujeol P, Bidet M, and Tauc M
- Subjects
- Animals, Basement Membrane metabolism, Calcium Channels metabolism, Carrier Proteins metabolism, Cell Membrane Permeability, Cells, Cultured, Cyclic AMP metabolism, Ion Transport, Kidney Tubules, Distal cytology, Membrane Potentials, Rabbits, Sodium metabolism, Sodium-Calcium Exchanger, Calcium metabolism, Kidney Tubules, Distal metabolism
- Published
- 1995
- Full Text
- View/download PDF
11. In young primary cultures of rabbit kidney cortical collecting ducts intercalated cells originate from principal or undifferentiated cells.
- Author
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Jamous M, Bidet M, Tauc M, Koechlin N, Gastineau M, Wanstok F, and Poujeol P
- Subjects
- Animals, Antibodies, Monoclonal, Arachis, Cell Differentiation physiology, Cells, Cultured, Hydrogen-Ion Concentration, Immunohistochemistry, Lectins, Male, Mitosis physiology, Peanut Agglutinin, Plant Lectins, Rabbits, Staining and Labeling, Kidney Cortex cytology, Kidney Tubules, Collecting cytology
- Abstract
The evolution of a primary culture of rabbit kidney cortical collecting tubule was followed over a period of 10 to 11 days. The cell types of this segment were characterized by using monoclonal antibodies, specifically directed against principal (Mab 703) and intercalated (Mab 503) cells of the apical membrane. The activity of a H+ pump ATPase was revealed in Mab 503-labeled cells, confirming that these cultured cells present characteristics of intercalated cells. The primary culture was also stained with peanut agglutinin (PNA), a specific ligand of beta intercalated cells. During the first two days, some cells, mainly Mab 503-labeled cells, disappeared, and cell division did not occur. At 2 days, the culture showed 80% and 18% of Mab 703-labeled and Mab 503-labeled cells, respectively. The first mitoses were observed at 2 days. From two to four days, cell division was nestly in Mab 703-labeled cells and only rarely seen in Mab 503-labeled cells, although during this period the proportion of Mab 703-labeled cells decreased to 44% of cells and that of Mab 503-labeled cells increased to 30%. The labeling with PNA was curious. Up to 2 days, PNA stained Mab 503-labeled cells, but from 4 days it stained other cells, probably dedifferentiated ones. In our culture conditions types of cells other than Mab 703-labeled and Mab 503-labeled cells occurred. First, throughout the life of the culture, some cells were not recognized by any monoclonal antibody; their number varied between 10 and 28% of the total cell number.(ABSTRACT TRUNCATED AT 250 WORDS)
- Published
- 1995
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