1. Heart transplantation for COVID-19 myopathy in the United States.
- Author
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Gill G, Roach A, Rowe G, Emerson D, Kobashigawa J, Lobo EP, Esmailian F, Bowdish ME, and Chikwe J
- Subjects
- Adult, Aged, Humans, Middle Aged, Young Adult, Muscular Diseases complications, Myocarditis etiology, Myocarditis surgery, Treatment Outcome, United States epidemiology, Cardiomyopathies epidemiology, Cardiomyopathies etiology, Cardiomyopathies surgery, COVID-19 complications, COVID-19 epidemiology, Heart Transplantation adverse effects, Heart Transplantation statistics & numerical data
- Abstract
Evidence on characteristics and outcomes of patients undergoing heart transplantation for coronavirus disease 2019 (COVID-19) associated cardiomyopathy is limited to case reports. Of all 6,332 patients aged ≥18 years undergoing heart transplantation from July 2020 through May 2022 in the United Network for Organ Sharing database, 12 (0.2%) patients had COVID-19 myocarditis and 98 (1.6%) patients with the same level of care had non-COVID-19 myocarditis. Their median age was 49 (range 19-74) years. All patients were hospitalized in the intensive care unit and 92.7% (n = 102) were on life support prior to transplantation. No patients with COVID-19 myocarditis required ventilation while waitlisted. Survival free from graft failure was 100% among COVID-19 patients and 88.5% among non-COVID-19 patients at a median of 257 (range 0-427) days post-transplant. These findings indicate that transplantation is rarely performed for COVID-19 related cardiomyopathy in the United States, yet early outcomes appear favorable in select patients., Competing Interests: Conflict of Interest Dr Emerson has received honoraria from Abiomed. None of the other authors have relevant conflicts of interest to disclose., (Copyright © 2023. Published by Elsevier Inc.)
- Published
- 2023
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