1. Impact of high-risk features for stage II adenocarcinoma of the appendix
- Author
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Mehmet Akce, Katerina Zakka, McKenna Penley, Renjian Jiang, Lana Khalil, Olatunji B. Alese, Walid L. Shaib, Christina Wu, Madhusmita Behera, and Bassel F. El-Rayes
- Subjects
Appendix adenocarcinoma ,Stage II ,High risk ,Low risk ,Adjuvant chemotherapy ,Clinical outcomes ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
Background: Clinico-pathological high-risk features are frequently utilized in adjuvant chemotherapy (AC) decisions in stage II colorectal cancer and their utility in stage II appendiceal adenocarcinoma (AA) is not established. The aim of this study is to determine the impact of high-risk features in clinical outcomes and whether high risk features are predictive of AC benefit in stage II AA. Methods: Patients with pathological stage II AA between 2010 and 2015 were identified from the National Cancer Database (NCDB) using ICD-O-3 morphology and topography codes: 8140, 8480 and C18.1. High risk stage II AA was defined as having at least one of the following clinicopathological features: T4 tumor,
- Published
- 2021
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