1. Effect of cupric chloride on oxidative metabolism in the freshwater teleost, Tilapia mossambica.
- Author
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Balavenkatasubbaiah M, Rani AU, Geethanjali K, Purushotham KR, and Ramamurthi R
- Subjects
- Animals, Fresh Water, L-Lactate Dehydrogenase metabolism, Lethal Dose 50, Liver enzymology, Liver metabolism, Muscles enzymology, Muscles metabolism, Oxidation-Reduction, Succinate Dehydrogenase metabolism, Copper toxicity, Fishes metabolism, Oxygen Consumption drug effects
- Abstract
The freshwater teleost Tilapia mossambica was subjected to lethal (6.0 mg X liter-1 = LC50/48 hr) and sublethal (1.5 mg X liter-1 copper treatment for 1, 7, and 14 days. The whole animal oxygen consumption and the activity levels of succinate dehydrogenase and lactate dehydrogenase in liver and muscle were studied. The decrease in oxygen consumption and succinate dehydrogenase activity and significant increase in lactate dehydrogenase activity suggest that the stressed fish is meeting its energy requirements through anaerobic oxidation and these enzymes can be used as indicators in monitoring metal-induced toxicity in fish.
- Published
- 1984
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