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Objectives: The performance of a new point-of-care CE-IVD-marked isothermal lab-on-phone COVID-19 assay was assessed in comparison to a gold standard real-time reverse transcriptase–PCR method. Methods: The study was conducted following a nonprobability sampling of ≥16-year-old volunteers from three different laboratories, using direct mouthwash (N = 24) or nasopharyngeal (N = 191) clinical samples. Results: The assay demonstrated 95.19% sensitivity and 100% specificity for detection of SARS-CoV-2 in direct nasopharyngeal crude samples and 78.95% sensitivity and 100% specificity in direct mouthwash crude samples. It also successfully detected currently predominant SARS-CoV-2 variants of concern (Beta B.1.351, Delta B.1.617.2, and Omicron B.1.1.529) and demonstrated to be inert against potential cross-reactions of other common respiratory pathogens that cause infections that present similar symptoms to COVID-19. Conclusion: This lab-on-phone pocket-sized assay relies on an isothermal amplification of SARS-CoV-2’s N and E genes, taking just 50 minutes from sample to result, with only 2 minutes of hands-on time. It presents good performance when using direct nasopharyngeal crude samples, enabling a low-cost, real-time, rapid, and accurate identification of SARS-CoV-2 infections at the point of care, which is important for both clinical management and population screening, as a tool to break the chain of transmission of COVID-19 pandemic, especially in low-resources environments.

Resumo: A miocardite é uma doença inflamatória do miocárdio. Pode‐se apresentar de forma subtil ou fulminante.Apresenta‐se o caso duma mulher de 39 anos com choque cardiogénico no contexto de miocardite fulminante, com necessidade de colocação de membrana de oxigenação extracorporal arteriovenosa como ponte para a recuperação. O estudo etiológico revelou infeção por Legionella pneumophila do serogrupo 1. Após início de antibioterapia com azitromicina endovenosa verificou‐se recuperação da função biventricular. Abstract: Myocarditis is defined as inflammation of the myocardium. The clinical manifestations of myocarditis vary from flu‐like symptoms to fatal fulminant forms.We report the case of a 39‐year‐old woman with a diagnosis of cardiogenic shock caused by fulminant myocarditis. Extracorporeal membrane oxygenation was used as a bridge to recovery.Etiological study revealed Legionella pneumophila serogroup 1 infection.Recovery of biventricular function was seen after treatment with azithromycin. Palavras‐chave: Miocardite, Choque cardiogénico, Legionella pneumophila, Membrana de oxigenação extracorporal, Keywords: Myocarditis, Cardiogenic shock, Legionella pneumophila, Extracorporeal membrane oxygenation