Search

Your search keyword '"Jeyabalan A"' showing total 90 results
Start Over Author "Jeyabalan A" Publisher elsevier
90 results on '"Jeyabalan A"'

2. Contributors

Author

Arunachalam, Murugan, primary, Benny, Renitta, additional, Boominathan, Muniyappan, additional, Borkar, Reema, additional, Chinnappa, Arivazhagan, additional, Chowdhury, Aniket, additional, Das, Neeladri, additional, De, Soumen, additional, Fernández, Gustavo, additional, Ghosh, Sushobhan, additional, Gupta, Ruchika, additional, Gupta, Rajeev, additional, KS, Nithish Kumar, additional, Kalathil, Krishnan Kartha, additional, Kedia, Moon, additional, Kumar, Saurabh, additional, Lin, Hong-Yu, additional, Mangalsana, Huidrom, additional, Mishra, Isha, additional, Mohan, Binduja, additional, Mohanty, Abhijeet, additional, Mondal, Bijnaneswar, additional, Nanjan, Pandurangan, additional, Neelakandan, Prakash P., additional, Pachisia, Sanya, additional, Phukon, Upasana, additional, Sahoo, Diptiprava, additional, Sarkar, Dipanjana, additional, Sathiyendiran, Malaichamy, additional, Shanmugapriya, Jeyabalan, additional, Shanmugaraju, Sankarasekaran, additional, Shanmughan, Ananthu, additional, Sivaraman, Gandhi, additional, Soumya, K.R., additional, Tyagi, Nidhi, additional, Vernekar, Amit A., additional, Wang, Yu-Te, additional, Xu, Lin, additional, and Zhang, Dawei, additional

Published
2023
Full Text
View/download PDF

3. A model system for antiviral siRNA therapeutics using exosome-based delivery

Author

Margaret Wallen, Farrukh Aqil, Raghuram Kandimalla, Jeyaprakash Jeyabalan, Supipi Auwardt, Neha Tyagi, David J. Schultz, Wendy Spencer, and Ramesh C. Gupta

Subjects
delivery strategies, exosomal delivery, siRNA therapeutics, SARS-CoV-2, antibodies, BSL2 viral model system, Therapeutics. Pharmacology, RM1-950
Abstract

Emerging viral diseases, such as Ebola, SARS, MERS, and the pathogen causing COVID-19, SARS-CoV-2, present a challenge for the development of therapeutics because of strict biosafety handling procedures and rapid mutation of their genomes. To facilitate the development of an adaptable and testable therapeutic model system, a colostrum exosome-based nanoparticle delivery system, EPM (exosome-PEI matrix), that overcomes stringent biosafety containment, was used to mimic the expression of viral proteins. This system would greatly expand the number of laboratories actively participating in the screening of potential therapeutics. EPM technology can deliver both plasmid DNA and siRNA to both simulate viral gene expression and screen potential antiviral siRNA therapeutics. Using this nanoplatform, three key SARS-CoV-2 proteins (the spike glycoprotein, nucleocapsid, and replicase) were expressed in vitro and in vivo. In vitro, several viral gene-targeting siRNAs were screened to determine knockdown efficiency, with some siRNA duplexes resulting in 80%–95% knockdown of corresponding protein expression. Moreover, in vivo experiments introducing the spike protein and nucleocapsid by EPM resulted in the production of antibodies against the viral antigen, measured up to 45 d after target delivery. Together, these findings support the efficacy of the EPM delivery system to establish a model for screening antiviral therapeutics-reduced biosafety level.

Published
2022
Full Text
View/download PDF

4. Shock waves impulses assisted hydrothermal method of synthesizing of organic 12-B polyanions and its applications

Author

Bharath Samannan, Yu-Shang Chen, Jothi Selvam, Praveen Peter, Yi-Li Lin, and Jeyabalan Thavasikani

Subjects
Hybrid material, Shock waves impulses, Dielectric studies, Membrane bacterial activity, Separation performance, Materials of engineering and construction. Mechanics of materials, TA401-492, Industrial electrochemistry, TP250-261
Abstract

To alleviate the problem, a new and unique property for the complex is desirable. Novel hexagonal stratified structures have been observed. This category of hybrid material is prepared with surfactant, polyoxometalate and s-triazine complex through ionic interaction. To know the tenacity of the present study for an inventive property was further studied. A novel technique of shock wave impulsed material was developed in this work; employed to fabricate the FO TFN membrane. The experimental results recommended that notable attention should be paid to the 0.1 wt % POM-AG incorporated TFN membrane which exhibits 9.2 LMH higher pure water flux compared to the composite membranes without shock imposed material incorporation that were synthesized. Those water enhancements of FO membranes could be assigned the presence of the POM-AG, which is allocated evenly throughout the PA active layer. Thus, the formation of porous selective layer is minimized water transport resistance. The dielectric and conduction mechanisms were monitored through dielectric anomalies and intramolecular charge transfer of the covalence of Mo-O and NH+, manifested by dipolar relaxation. An unassociated in intensity originated from the differential of the selective orientation during the analyses of the experimental data for the powder samples. Furthermore, the structural, morphological and thermal properties of hock wave impulsed hybrid material have been investigated using XRD, SEM, FT-IR, TGA, and NMR techniques. However, the FO membrane biological activity was reported above 70%.

Published
2023
Full Text
View/download PDF

5. List of contributors

Author

Adhikari, Nav Raj, primary, Agrawal, Ganesh Kumar, additional, Ahmad, Niaz, additional, Ahmad, Rumana, additional, Araujo, Fabricio Almeida, additional, Aslam, Sidra, additional, Aydın, Yıldız, additional, Barh, Debmalya, additional, Benkeblia, Noureddine, additional, Benko-Iseppon, Ana Maria, additional, Bhardwaj, Ragini, additional, Binneck, Eliseu, additional, Bozhilova-Sakova, Milena Georgieva, additional, Braga, Marcus de Barros, additional, Buckseth, Tanuja, additional, Challam, Clarissa, additional, Choudhary, Ashish Kumar, additional, da Silva, Manassés, additional, da Silva, Wilson, additional, Das, Sauren, additional, De Los Santos, Edian Franklin Franco, additional, Dhakar, Kusum, additional, Dhir, Sunny, additional, Dhkal, Manmohan, additional, Dimitrova, Ivona Vassileva, additional, Dwivedi, Shruti, additional, Dwivedi, Upendra N., additional, Dwivedi, Vikas, additional, Eizenberg, Hanan, additional, Elias, Sabrina, additional, Ferreira-Neto, José Ribamar Costa, additional, Freilich, Shiri, additional, Gaikwad, Kishor, additional, Gaur, Rajarshi Kumar, additional, Gautam, Ranjana, additional, Ghosh, Sewali, additional, Gilles, Tijs, additional, Gupta, Archit, additional, Gupta, Kapil, additional, Gupta, Om Prakash, additional, Gupta, Ravi, additional, Gupta, Romasha, additional, Gupta, Supriya, additional, Haque, Taslima, additional, Hazra, Anjan, additional, Hossain, Md. Anowar, additional, Iyer, Niranjani, additional, Jaiswar, Akanksha, additional, Jasrotia, Rahul Singh, additional, Kaila, Tanvi, additional, Kamboj, Disha, additional, Kaur, Manjot, additional, Kaur, Parampreet, additional, Kaur, Ramandeep, additional, Khatri, Nisha, additional, Kido, Éderson Akio, additional, Kim, Sun Tae, additional, Kumar, Ashwani, additional, Kumar, Dileep, additional, Kumar, Manoj, additional, Kumar, Pradeep, additional, Kumar, Pravin, additional, Kumar, Satish, additional, Kumar, Shailesh, additional, Kushwaha, Ujjawal Kumar Singh, additional, Lucas, Stuart J., additional, Mahadani, Pradosh, additional, Malo, Richard, additional, Maurya, Suresh Kumar, additional, Meena, Nand Lal, additional, Meena, Vijay Singh, additional, Mehmood, Muhammad Aamer, additional, Minkina, Tatiana, additional, Mishra, Chandra Nath, additional, Mohideen, Habeeb Shaik, additional, Mor, Poonam, additional, Mukhopadhyay, Kunal, additional, Nanda, Satyabrata, additional, Narad, Priyanka, additional, Narayan, Aditya, additional, Natarajan, Nandakumar, additional, Negi, Chandranandani, additional, Nehra, Chitra, additional, Noor, Fatima, additional, Pal, Lalita, additional, Pandey, Veda P., additional, Petrov, Nikolay Manchev, additional, Poddar, Raju, additional, Prasad, Birendra, additional, Rahman, Mehboob-ur, additional, Rajput, Vishnu D., additional, Rakwal, Randeep, additional, Ramos, Rommel Thiago Jucá, additional, Rani, Asha, additional, Redhu, Neeru S., additional, Rishi, Narayan, additional, Riyazuddin, Riyazuddin, additional, Ronen, Zeev, additional, Sangeetha, Jeyabalan, additional, Sarkar, Abhijit, additional, Satapathy, Lopamudra, additional, Sengupta, Abhishek, additional, Seraj, Zeba, additional, Shahid, Saima, additional, Sharma, Pradeep, additional, Sharma, Priti, additional, Sharma, Swati, additional, Sheikh, Imran, additional, Shohan, Mohammad Umer Sharif, additional, Singh, Abhishek, additional, Singh, Ajeet, additional, Singh, Anil Kumar, additional, Singh, Anuradha, additional, Singh, Dharmendra, additional, Singh, Gyanendra Pratap, additional, Singh, Nisha, additional, Singh, Rajesh K., additional, Sonawala, Kevina, additional, Srivastava, Sudhanshu, additional, Stoyanova, Mariya Ivanova, additional, Tanveer, Aiman, additional, Thakur, Zoozeal, additional, Thangadurai, Devarajan, additional, Tiwari, Jagesh Kumar, additional, Tiwary, Basant K., additional, Torres, Renato Hidaka, additional, Tripathy, Sanjaya Shankar, additional, Tyagi, Aruna, additional, Ujinwal, Megha, additional, Uncuoğlu, Ahu Altınkut, additional, Verma, Rakesh Kumar, additional, Vyas, Pritesh, additional, Yadav, Ajit Kumar Singh, additional, Yadav, Anurag, additional, Yadav, Dinesh, additional, Yadav, Kanchan, additional, Yadav, Kusum, additional, Yadav, Manoj Kumar, additional, Yadav, Pramod Kumar, additional, Yashveer, Shikha, additional, Zarecki, Raphy, additional, and Şahin, Ezgi Çabuk, additional

Published
2022
Full Text
View/download PDF

6. Genomics and its role in crop improvement

Author

Kushwaha, Ujjawal Kumar Singh, primary, Adhikari, Nav Raj, additional, Prasad, Birendra, additional, Maurya, Suresh Kumar, additional, Thangadurai, Devarajan, additional, and Sangeetha, Jeyabalan, additional

Published
2022
Full Text
View/download PDF

9. List of Contributors

Author

Bakrania, Bhavisha A., primary, Bernstein, Ira M., additional, Burton, Graham J., additional, Cindrova-Davies, Tereza, additional, Cipolla, Marilyn J., additional, Conrad, Kirk P., additional, Davidge, Sandra T., additional, de Groot, Christianne, additional, Dechend, Ralf, additional, Figueiro-Filho, Ernesto, additional, Fisher, Susan J., additional, George, Eric M., additional, Gernand, Alison D., additional, Goulopoulou, Styliani, additional, Granger, Joey P., additional, Gray, Kathryn J., additional, Hauspurg, Alisse, additional, Hibbard, Judith U., additional, Hubel, Carl A., additional, Jeyabalan, Arun, additional, Karumanchi, S. Ananth, additional, Kenny, Louise, additional, Laivuori, Hannele, additional, LaMarca, Babbette, additional, Lindheimer, Marshall D., additional, Miller, Eliza C., additional, Navaratnam, Kate, additional, Ontiveros, Alejandra E., additional, Rana, Sarosh, additional, Redman, Christopher W.G., additional, Rich-Edwards, Janet W., additional, Robertson, Sarah A., additional, Roberts, James M., additional, Schalekamp-Timmermans, Sarah, additional, Shroff, Sanjeev G., additional, Staff, Anne Cathrine, additional, Stillman, Isaac E., additional, Stuart, Jennifer J., additional, Taylor, Robert N., additional, Umans, Jason G., additional, Vatish, Manu, additional, Ward, Kenneth, additional, Wiles, Kate, additional, and Yung, Hong Wa, additional

Published
2022
Full Text
View/download PDF

12. Generation of iPSC line (GLNNFi001-A) from peripheral blood mononuclear cells of a patient with macular corneal dystrophy

Author

Koushik Chakrabarty, K.N. Prashanthi, Rohit Shetty, Shubham Argulwar, Nallathambi Jeyabalan, and Arkasubhra Ghosh

Subjects
Biology (General), QH301-705.5
Abstract

Macular corneal dystrophy (MCD) an autosomal recessive disorder leading to severe visual impairment is caused by mutations in the carbohydrate sulfotransferase 6 (CHST6) gene. Here, we describe generation of a iPSC line from peripheral blood mononuclear cells (PBMCs) from a 38 year old MCD patient harboring a homozygous mutation, p.V172L in the CHST6 gene. The iPSC line GLNNFi001-A was generated using an integration-free Sendai virus containing (KLF4, c-MYC, OCT4 and SOX2).

Published
2022
Full Text
View/download PDF

13. Rituximab in Membranous Nephropathy

Author

Philipp Gauckler, Jae Il Shin, Federico Alberici, Vincent Audard, Annette Bruchfeld, Martin Busch, Chee Kay Cheung, Matija Crnogorac, Elisa Delbarba, Kathrin Eller, Stanislas Faguer, Kresimir Galesic, Siân Griffin, Martijn W.F. van den Hoogen, Zdenka Hrušková, Anushya Jeyabalan, Alexandre Karras, Catherine King, Harbir Singh Kohli, Gert Mayer, Rutger Maas, Masahiro Muto, Sergey Moiseev, Balazs Odler, Ruth J. Pepper, Luis F. Quintana, Jai Radhakrishnan, Raja Ramachandran, Alan D. Salama, Ulf Schönermarck, Mårten Segelmark, Lee Smith, Vladimír Tesař, Jack Wetzels, Lisa Willcocks, Martin Windpessl, Ladan Zand, Reza Zonozi, and Andreas Kronbichler

Subjects
B cells, membranous nephropathy, nephrotic syndrome, rituximab, Diseases of the genitourinary system. Urology, RC870-923
Abstract

Membranous nephropathy (MN) is the most common cause of primary nephrotic syndrome among adults. The identification of phospholipase A2 receptor (PLA2R) as target antigen in most patients changed the management of MN dramatically, and provided a rationale for B-cell depleting agents such as rituximab. The efficacy of rituximab in inducing remission has been investigated in several studies, including 3 randomized controlled trials, in which complete and partial remission of proteinuria was achieved in approximately two-thirds of treated patients. Due to its favorable safety profile, rituximab is now considered a first-line treatment option for MN, especially in patients at moderate and high risk of deterioration in kidney function. However, questions remain about how to best use rituximab, including the optimal dosing regimen, a potential need for maintenance therapy, and assessment of long-term safety and efficacy outcomes. In this review, we provide an overview of the current literature and discuss both strengths and limitations of “the new standard.”

Published
2021
Full Text
View/download PDF

14. Primary Presentation of Pulmonary Hypertension in the Peripartum

Author

Malamo E. Countouris, MD, Arun Jeyabalan, MD, MS, John C. Caldwell, MD, Jenifer E. Lee, MD, and Gavin W. Hickey, MD

Subjects
anesthesia, congenital heart defect, hemodynamics, pregnancy, pulmonary hypertension, Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract

A Bosnian woman at 20 weeks’ gestation presented with dyspnea and hypoxia. She was diagnosed with Eisenmenger physiology with severe pulmonary hypertension, ventricular septal defect, and patent ductus arteriosus. Given high maternal mortality, coordination of care with a multidisciplinary team approach may allow for best possible outcomes. (Level of Difficulty: Intermediate.)

Published
2020
Full Text
View/download PDF

17. List of contributors

Author

Adetunji, Charles Oluwaseun, primary, Adimula, Vincent, additional, Ali, Muhammad Arif, additional, Al-Tawaha, Abdel Rahman Mohammad Said, additional, Andrea, Pérez-Moreno, additional, Arshad, Muhammad, additional, Arunachalam, Kantha D., additional, Azeez, Luqmon, additional, Bakht, Burera Khush, additional, Baysal, Asli, additional, Braun, Adeli Beatriz, additional, Chaudhary, Manoj, additional, Darwesh, Osama M., additional, Das, Chinmaya Kumar, additional, Denisse, Valle-García Jessica, additional, Dowlath, Mohammed Junaid Hussain, additional, Fabián, Fernández-Luqueño, additional, Govindasamy, Prabhu, additional, Gul, Amir-Ali Khalil, additional, Gul, Iram, additional, Harikumar, P.S., additional, Hermes, Pérez-Hernández, additional, Iftikhar, Mahnoor, additional, Islam, Saher, additional, Jaseela, C., additional, Jency, D. Arockia, additional, Jesitha, K., additional, Karuppannan, Sathish Kumar, additional, Khalaki, Masoomeh Abassi, additional, Kumar, Anup, additional, Mahawer, Sonu Kumar, additional, Matter, Hamdy A.B., additional, Matter, Ibrahim A., additional, Minkina, Tatiana M., additional, Moameri, Mehdi, additional, Moghal, Arif Ali Baig, additional, Mohammed, Syed Abu Sayeed, additional, Mohan, Dinesh, additional, Nguyen, Tuan Anh, additional, Ogunkunle, Clement Oluseye, additional, Okoro, Hussein Kehinde, additional, Oyedeji, Stephen, additional, Parvathi, V. Poornima, additional, Patel, Manvendra, additional, Patricio, Torres-Gómez Andrés, additional, Pittman, Charles U., additional, Prasad, Mahendra, additional, Pratap, Tej, additional, Rajput, Vishnu D., additional, Ramakrishnan, Srinivasan, additional, Roberto, Sarabia-Castillo Cesar, additional, Said Al-Tawaha, Abdel Rahman Mohammad, additional, Sangeetha, Jeyabalan, additional, Saygin, Hasan, additional, Shah, Ghulam Mujtaba, additional, Shettar, Arun Kashivishwanath, additional, Singh, Ajeet, additional, Singh, Nakshatra Bahadur, additional, Singh, Vipin K., additional, Suriyaprakash, Rajadesingu, additional, Sushkova, Svetlana, additional, Thangadurai, Devarajan, additional, Thomé, Antônio, additional, Trentin, Adan William da Silva, additional, Umadevi, M., additional, Visentin, Caroline, additional, and Zahedifar, Maryam, additional

Published
2021
Full Text
View/download PDF

19. Breastfeeding, Cellular Immune Activation, and Myocardial Recovery in Peripartum Cardiomyopathy

Author

Agnes Koczo, MD, Amy Marino, MD, Arun Jeyabalan, MD, Uri Elkayam, MD, Leslie T. Cooper, MD, James Fett, MD, MPH, Joan Briller, MD, Eileen Hsich, MD, Lori Blauwet, MD, Charles McTiernan, PhD, Penelope A. Morel, MD, Karen Hanley-Yanez, BS, Dennis M. McNamara, MD, MS, Dennis M McNamara, MD, James D. Fett, MD, Jessica Pisarcik, RN, BSN, John Gorcsan, III, MD, Erik Schelbert, MD, Rami Alharethi, MD, Kismet Rasmusson, CRNP, Kim Brunisholz, Amy Butler, BS, CCRP, Deborah Budge, A.G. Kfoury, MD, Benjamin Horne, PhD, Joe Tuinei, Heather Brown, Julie Damp, MD, Allen J. Naftilan, MD, Jill Russell, RN, MSN, Darla Freehardt, LPN, BS, CCRP, Cynthia Oblak, CCRC, Greg Ewald, MD, Donna Whitehead, RN, Jean Flanagan, RN, Anne Platts, Jorge Caro, MPH, Stephanie Mullin, RN, Michael M. Givertz, MD, M. Susan Anello, RN, BS, Navin Rajagopalan, MD, David Booth, MD, Tiffany Sandlin, RN, Wendy Wijesiri, RN, Lori A. Blauwet, MD, Joann Brunner, RN, Mary Phelps, Ruth Kempf, Kalgi Modi, MD, Tracy Norwood, Decebal Sorin Griza, MD, G. Michael Felker, MD, Robb Kociol, MD, Patricia Adams, RN, Gretchen Wells, MD, Vinay Thohan, MD, Deborah Wesley-Farrington, RN, BSN, CCRC, CCA, Sandra Soots, RN, CCRC, Richard Sheppard, MD, Caroline Michel, MD, Nathalie Lapointe, RN, PhD, Heather Nathaniel, Angela Kealey, MD, Marc Semigran, MD, Maureen Daher, RN, John Boehmer, MD, David Silber, MD, Eric Popjes, MD, Patricia Frey, RN, Todd Nicklas, RN, Jeffrey Alexis, MD, Lori Caufield, RN, BSN, CCRC, John W. Thornton, III, MD, Mindy Gentry, MD, Vincent J.B. Robinson, MBBS, Gyanendra K. Sharma, MD, Joan Holloway, BS, Maria Powell, LPN, CCRC, David Markham, MD, Mark Drazner, MD, Lynn Fernandez, RN, Mark Zucker, MD, David A. Baran, MD, Martin L. Gimovsky, MD, Natalia Hochbaum, MD, Bharati Patel, RN, CCRC, Laura Adams, RN, BSN, Gautam Ramani, MD, Stephen Gottlieb, MD, Shawn Robinson, MD, Stacy Fisher, MD, Joanne Marshall, BSN, MS, Jennifer Haythe, MD, Donna Mancini, MD, Rachel Bijou, MD, Maryjane Farr, MD, Marybeth Marks, Henry Arango, Biykem Bozkurt, MD, PhD, FACC, FAHA, Mariana Bolos, Paul Mather, MD, Sharon Rubin, MD, Raphael Bonita, MD, Susan Eberwine, RN, Hal Skopicki, MD, PhD, Kathleen Stergiopoulos, MD, Ellen McCathy-Santoro, MD, Jennifer Intravaia, RN, CCRCII, Elizabeth Maas, Jordan Safirstein, MD, Audrey Kleet, RN, MS, ACNP-BC, CCRN, CCTC, Nancy Martinez, RN, Christine Corpoin, RN, Donna Hesari, RN, Sandra Chaparro, MD, Laura J. Hudson, MA, MPH, CCRC, Jalal K. Ghali, MD, Zora Injic, RN, BSc, MSA, and Ilan S. Wittstein, MD

Subjects
Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract

Summary: The etiology of peripartum cardiomyopathy remains unknown. One hypothesis is that an increase in the 16-kDa form of prolactin is pathogenic and suggests that breastfeeding may worsen peripartum cardiomyopathy by increasing prolactin, while bromocriptine, which blocks prolactin release, may be therapeutic. An autoimmune etiology has also been proposed. The authors investigated the impact of breastfeeding on cellular immunity and myocardial recovery for women with peripartum cardiomyopathy in the IPAC (Investigations in Pregnancy Associated Cardiomyopathy) study. Women who breastfed had elevated prolactin, and prolactin levels correlated with elevations in CD8+ T cells. However, despite elevated prolactin and cytotoxic T cell subsets, myocardial recovery was not impaired in breastfeeding women. Key Words: breastfeeding, immune activation, peripartum cardiomyopathy

Published
2019
Full Text
View/download PDF

20. Contributors

Author

Albright, Robert C., primary, Amerling, Richard, additional, Angeli, Paolo, additional, Angelotti, Maria Lucia, additional, Antonelli, Massimo, additional, Antoniotti, Riccardo, additional, Arulkumaran, Nishkantha, additional, Asfar, Pierre, additional, Ash, Stephen R., additional, Aucella, Filippo, additional, Aucella, Francesco, additional, Ave, Samuele, additional, Bagshaw, Sean M., additional, Balaraman, Vasanthi, additional, Baldwin, Ian, additional, Bargman, Joanne M., additional, Barletta, Gina-Marie, additional, Barletta, Jeffrey F., additional, Barnela, Shriganesh R., additional, Bayır, Hülya, additional, Beaulieu, Monica, additional, Bellasi, Antonio, additional, Bellomo, Rinaldo, additional, Beloncle, François, additional, Bhansali, Arjun, additional, Bihorac, Azra, additional, Billings, Frederic T., additional, Birk, Horst-Walter, additional, Bonilla-Reséndiz, Luis Ignacio, additional, Bouchard, Josée, additional, Bourke, Edmund, additional, Braitberg, George, additional, Brendolan, Alessandra, additional, Brocca, Alessandra, additional, Brophy, Patrick D., additional, Bucala, Richard, additional, Bunchman, Timothy E., additional, Burdmann, Emmanuel A., additional, Busse, Laurence W., additional, Caires, Renato Antunes, additional, Caironi, Pietro, additional, Camilla, Roberta, additional, Campos, Israel, additional, Canaud, Bernard, additional, Cantaluppi, Vincenzo, additional, Martinez, Maria P., additional, Capasso, Giovambattista, additional, Carcillo, Joseph A., additional, Carlesso, Eleonora, additional, Casino, Francesco G., additional, Castellano, Giuseppe, additional, Catania, Matteo, additional, Cawcutt, Kelly A., additional, Cerda, Jorge, additional, Charen, Elliot, additional, Chawla, Lakhmir S., additional, Chiaramonte, Stefano, additional, Chua, Horng-Ruey, additional, Cianciaruso, Bruno, additional, Ciceri, Paola, additional, Cieslak, Jacek, additional, Clark, William R., additional, Claure-Del Granado, Rolando, additional, Clementi, Anna, additional, Co, Ivan N., additional, Coelho, Fernanda Oliveira, additional, Conte, Ferruccio, additional, Corey, Howard E., additional, Cosmai, Laura, additional, Costalonga, Elerson Carlos, additional, Costamagna, Andrea, additional, Costanzo, Maria Rosa, additional, Cozzolino, Mario, additional, Cramer, Carl H., additional, Cravedi, Paolo, additional, Crepaldi, Carlo, additional, Creteur, Jacques, additional, Crew, R. John, additional, da Costa e Silva, Verônica Torres, additional, Davenport, Andrew, additional, Davies, Andrew R., additional, D'Costa, Rohit, additional, Dean, Dawson F., additional, Debiais, Charlotte, additional, de Cal, Massimo, additional, Dedhia, Paras, additional, de Grooth, Harm-Jan, additional, Dell'Aquila, Roberto, additional, Dellepiane, Sergio, additional, Dellinger, Richard Phillip, additional, Del Vecchio, Lucia, additional, Depner, Thomas A., additional, De Rosa, Silvia, additional, Deutschman, Clifford S., additional, Devarajan, Prasad, additional, Dewitte, A., additional, Di Iorio, Biagio R., additional, Di Lullo, Luca, additional, Di Micco, Lucia, additional, Di Nardo, Matteo, additional, Ding, Xiaoqiang, additional, D'Ippoliti, Fiorella, additional, Di Somma, Salvatore, additional, Doi, Kent, additional, Dries, David J., additional, Druml, Wilfred, additional, Duke, Graeme, additional, Durand, Francois, additional, Eadon, Michael T., additional, Eckstein, Devin, additional, Egi, Moritoki, additional, Eiam-Ong, Somchai, additional, Elbers, Paul W.G., additional, Elli, Francesca, additional, Elliott, Steve, additional, Emlet, David R., additional, Endre, Zoltan, additional, Evans, Roger G., additional, Fanelli, Vito, additional, Fattahi, Fatemeh, additional, Federspiel, Christine Kinggaard, additional, Ferrada, Marcela A., additional, Ferrari, Fiorenza, additional, Fiaccadori, Enrico, additional, Fiorentino, Marco, additional, Fisher, Caleb, additional, Flessner, Michael F., additional, Formica, Marco, additional, Forni, Lui G., additional, Francoz, Claire, additional, French, Craig, additional, Fuhrman, Dana Y., additional, Fumagalli, Giordano, additional, Galbusera, Miriam, additional, Gallieni, Maurizio, additional, Gammill, Hilary S., additional, Gao, Dayong, additional, Garzotto, Francesco, additional, Gatta, Giuseppe, additional, Genga, Kelly R., additional, Genovesi, Simonetta, additional, Genyk, Yuri S., additional, Geradin, Christel, additional, Gesualdo, Loreto, additional, Giavarina, Davide, additional, Giuliani, Anna, additional, Glezerman, Ilya G., additional, Goldstein, Stuart L., additional, Golper, Thomas A., additional, Gómez, Hernando, additional, Granata, Antonio, additional, Grandaliano, Giuseppe, additional, Grasselli, Giacomo, additional, Groeneveld, A.B. Johan, additional, Guerci, Philippe, additional, Gunnerson, Kyle J., additional, Harbord, Nikolas, additional, Harshman, Lyndsay A., additional, Hennessy, Anthony J., additional, Hill, Graham L., additional, Hobson, Charles, additional, Hohenstein, Bernd, additional, Honoré, Patrick M., additional, Horwitz, Edward, additional, Hosseinian, Leila, additional, Hoste, Eric A.J., additional, House, Andrew A., additional, Humes, H. David, additional, Husain-Syed, Faeq, additional, Ince, Can, additional, Ing, Todd S., additional, Jacobs, Rita, additional, Jaswal, Dharmvir, additional, Jeyabalan, Arun, additional, Joannes-Boyau, Olivier, additional, Joannidis, Michael, additional, Joyce, Emily, additional, Kane-Gill, Sandra L., additional, Kaplan, Lewis J., additional, Kashani, Kianoush, additional, Katz, Nevin, additional, Kellum, John A., additional, Khanna, Ramesh, additional, Kim-Campbell, Nahmah, additional, King, Joshua D., additional, Kirwan, Christopher J., additional, Kiss, Joseph E., additional, Klein, David, additional, Kotanko, Peter, additional, Krediet, Raymond T., additional, Kuhlmann, Martin K., additional, Kuiper, Jan Willem, additional, Lachance, Philippe, additional, Lameire, Norbert, additional, Langer, Thomas, additional, Lankadeva, Yugeesh R., additional, Laurin, Louis-Philippe, additional, Lazzeri, Elena, additional, Leblanc, Martine, additional, Lefebvre, Joannie, additional, Lentini, Paolo, additional, Leray-Moragués, Hélène, additional, Levin, Adeera, additional, Lew, Susie Q., additional, Liapis, Helen, additional, Liu, Kathleen D., additional, Livigni, Sergio, additional, Locatelli, Francesco, additional, Lorenzin, Anna, additional, Lu, Jian-Da, additional, Lu, Renhua, additional, Lysak, Nicholas, additional, Macedo, Etienne, additional, Madan, Niti, additional, Madore, François, additional, Maerz, Linda L., additional, Maiden, Matthew J., additional, Malhotra, Rakesh, additional, Marengo, Marita, additional, Mariano, Filippo, additional, Marik, Paul E., additional, Marini, John J., additional, Marino, Rossella, additional, Marshall, Mark R., additional, Mårtensson, Johan, additional, Matsuura, Ryo, additional, May, Clive N., additional, Mazzone, Patrizio, additional, McCauley, Jerry, additional, McCullough, Peter A., additional, McMahon, Blaithin A., additional, Mehta, Ravindra L., additional, Mele, Caterina, additional, Menon, Madhav, additional, Meola, Mario, additional, Mérouani, Aicha, additional, Meuwly, Jean-Yves, additional, Milla, Paola, additional, Misra, Madhukar, additional, Misra, Paraish S., additional, Mizock, Barry A., additional, Modi, Jwalant R., additional, Moeckel, Gilbert, additional, Molitoris, Bruce A., additional, Morabito, Santo, additional, Mucelli, Roberto Pozzi, additional, Murray, Patrick T., additional, Murugan, Raghavan, additional, Nadim, Mitra K., additional, Nair, Devika, additional, Nalesso, Federico, additional, Neri, Mauro, additional, Nguyen, Trung C., additional, Ni, Zhaohui, additional, Noris, Marina, additional, Novick, Tessa, additional, O'Horo, John C., additional, Okusa, Mark Douglas, additional, Opal, Steven M., additional, Opdam, Helen Ingrid, additional, Ostermann, Marlies, additional, Ottaviano, Emerenziana, additional, Oudemans-van Straaten, Heleen M., additional, Overgaard-Steensen, Christian, additional, Padalino, Massimo A., additional, Panichi, Vincenzo, additional, Parameswaran, Priyanka, additional, Patel, Samir S., additional, Payen, Didier, additional, Pea, Federico, additional, Peacock, W. Frank, additional, Peart, Sandrica Young, additional, Peerapornratana, Sadudee, additional, Pelosi, Paolo, additional, Peng, Zhi-Yong, additional, Perico, Norberto, additional, Peruzzi, Licia, additional, Pesce, Francesco, additional, Pesenti, Antonio, additional, Petrucci, Ilaria, additional, Pham, Phuong-Chi, additional, Pham, Phuong-Thu, additional, Phoon, Richard K.S., additional, Piano, Salvatore, additional, Pinsky, Michael R., additional, Piquilloud, Lise, additional, Pistolesi, Valentina, additional, Plank, Lindsay D., additional, Plötz, Frans B., additional, Podestá, Manuel Alfredo, additional, Porta, Camillo, additional, Pozzato, Marco, additional, Prencipe, Michele, additional, Prowle, John R., additional, Puthucheary, Zudin A., additional, Qu, Lirong, additional, Rachoin, Jean-Sebastien, additional, Radhakrishnan, Jai, additional, Ranieri, V. Marco, additional, Ratanarat, Ranistha, additional, Remuzzi, Giuseppe, additional, Resnick, Shelby, additional, Rewa, Oleksa G., additional, Ricci, Zaccaria, additional, Ridel, Christophe, additional, Rifai, Kinan, additional, Ring, Troels, additional, Rizo-Topete, Lilia M., additional, Roessler, Eric, additional, Romagnani, Paola, additional, Romagnoli, Stefano, additional, Ronco, Claudio, additional, Ronco, Federico, additional, Rosner, Mitchell H., additional, Rossetti, Emanuele, additional, Russell, James A., additional, Saab, Georges, additional, Sabatino, Alice, additional, Saboo, Sonali S., additional, Samoni, Sara, additional, Sappington, Penny Lynn, additional, Sartori, Marco, additional, Savige, Judy, additional, Schena, Francesco Paolo, additional, Schneider, Antoine Guillaume, additional, Schraverus, Pieter, additional, Schulte, Wibke, additional, Segoloni, Giuseppe, additional, Semler, Matthew W., additional, Sharma, Aashish, additional, Shaw, Andrew, additional, Sheth, Naitik, additional, Shukla, Ashutosh, additional, Siddall, Eric C., additional, Sievers, Theodore M., additional, Siew, Edward D., additional, Singbartl, Kai, additional, Singer, Mervyn, additional, Singh, Pooja, additional, Smith, Loren E., additional, Soni, Sachin S., additional, Soto, Mara Serrano, additional, Spapen, Herbert D., additional, Srisawat, Nattachai, additional, Srivastava, Ajay, additional, Stellin, Giovanni, additional, Symons, Jordan M., additional, Szamosfalvi, Balazs, additional, Tai, Kian Bun, additional, Takalkar, Unmesh V., additional, Teitelbaum, Isaac, additional, Tetta, Ciro, additional, Thakar, Charuhas V., additional, Tonon, Marta, additional, Trepiccione, Francesco, additional, Triulzi, Darrell, additional, Tushar, Chopra, additional, Uchino, Shigehiko, additional, Valika, Ali, additional, Van Biesen, Wim, additional, Vandenberghe, Wim, additional, Vanholder, Raymond, additional, Vanmassenhove, Jill, additional, Verbine, Anton, additional, Vergano, Marco, additional, Villa, Gianluca, additional, Villeneuve, Pierre-Marc, additional, Vincent, Jean-Louis, additional, Vinsonneau, Christophe, additional, Virzì, Grazia Maria, additional, Visconti, Federico, additional, Visvanathan, Ravindran, additional, Van Vong, Li, additional, Walmrath, Hans-Dieter, additional, Ward, Peter A., additional, Weir, Matthew A., additional, Wen, Xiaoyan, additional, Wendon, Julia, additional, Winchester, James Frank, additional, Wong, Adrian, additional, Woodhouse, Elke L., additional, Xue, Jun, additional, Yadav, Anju, additional, Yerram, Preethi, additional, Yessayan, Lenar, additional, Yeun, Jane Y., additional, Yu, Alex W., additional, Zaccaria, Marta, additional, Zacchia, Miriam, additional, Zachariah, Teena P., additional, Zamperetti, Nereo, additional, Zampieri, Fernando G., additional, Zanco, Pierluigi, additional, Zanella, Alberto, additional, Zanoli, Luca, additional, Zappitelli, Michael, additional, Zaragoza, Jose J., additional, Zarbock, Alexander, additional, Zaroccolo, Marta, additional, Zhang, Han, additional, and Zimmer, Andrea, additional

Published
2019
Full Text
View/download PDF

23. Contributors

Author

Murugan Arunachalam, Renitta Benny, Muniyappan Boominathan, Reema Borkar, Arivazhagan Chinnappa, Aniket Chowdhury, Neeladri Das, Soumen De, Gustavo Fernández, Sushobhan Ghosh, Ruchika Gupta, Rajeev Gupta, Nithish Kumar KS, Krishnan Kartha Kalathil, Moon Kedia, Saurabh Kumar, Hong-Yu Lin, Huidrom Mangalsana, Isha Mishra, Binduja Mohan, Abhijeet Mohanty, Bijnaneswar Mondal, Pandurangan Nanjan, Prakash P. Neelakandan, Sanya Pachisia, Upasana Phukon, Diptiprava Sahoo, Dipanjana Sarkar, Malaichamy Sathiyendiran, Jeyabalan Shanmugapriya, Sankarasekaran Shanmugaraju, Ananthu Shanmughan, Gandhi Sivaraman, K.R. Soumya, Nidhi Tyagi, Amit A. Vernekar, Yu-Te Wang, Lin Xu, and Dawei Zhang

Published
2023
Full Text
View/download PDF

24. Sustained expression of CYPs and DNA adduct accumulation with continuous exposure to PCB126 and PCB153 through a new delivery method: Polymeric implants

Author

Farrukh Aqil, Hua Shen, Jeyaprakash Jeyabalan, Xing Xin, Hans-Joachim Lehmler, Gabriele Ludewig, Larry W. Robertson, and Ramesh C. Gupta

Subjects
Polychlorinated biphenyls (PCBs), PCB126 (3,3′,4,4′,5-pentachlorobiphenyl), PCB153 (2,2′,4,4′,5,5′-hexachlorobiphenyl), Polymeric implants, DNA adducts, 32P-postlabeling, CYPs, Paraoxonase 1 (PON1), Toxicology. Poisons, RA1190-1270
Abstract

A new delivery method via polymeric implants was used for continuous exposure to PCBs. Female Sprague-Dawley rats received subcutaneous polymeric implants containing PCB126 (0.15% load), PCB153 (5% load), or both, for up to 45 d and release kinetics and tissue distribution were measured. PCB153 tissue levels on day 15 were readily detected in lung, liver, mammary and serum, with highest levels in the mammary tissue. PCB126 was detected only in liver and mammary tissues. However, a completely different pharmacokinetics was observed on co-exposure of PCB153 and PCB126, with a 1.8-fold higher levels of PCB153 in the liver whereas a 1.7-fold lower levels in the mammary tissue. PCB126 and PCB153 caused an increase in expression of key PCB-inducible enzymes, CYP 1A1/2 and 2B1/2, respectively. Serum and liver activities of the antioxidant enzymes, PON1 and PON3, and AhR transcription were also significantly increased by PCB126. 32P-postlabeling for polar and lipophilic DNA-adducts showed significant quantitative differences: PCB126 increased 8-oxodG, an oxidative DNA lesion, in liver and lung tissues. Adduct levels in the liver remained upregulated up to 45 d, while some lung DNA adducts declined. This is the first demonstration that continuous low-dose exposure to PCBs via implants can produce sustained tissue levels leading to the accumulation of DNA-adducts in target tissue and induction of indicator enzymes. Collectively, these data demonstrate that this exposure model is a promising tool for long-term exposure studies.

Published
2014
Full Text
View/download PDF

25. Synthesis and antimicrobial activity of N1-(3-chloro-4-fluorophenyl)-N4-substituted semicarbazone derivatives

Author

Mohamed Jawed Ahsan, Mohd Amir, Mohamed Afroz Bakht, Jeyabalan Govinda Samy, Mohamed Zaheen Hasan, and Md Shivli Nomani

Subjects
Semicarbazones, Antibacterial agents, Antifungal agents, Lipinski-Rule of Five, Chemistry, QD1-999
Abstract

A series of 16 N1-(3-chloro-4-fluorophenyl)-N4-substituted semicarbazone derivatives were synthesized and subjected to computational pharmacokinetic studies to predict molecular properties. All the title compounds (4a–p) followed the Lipinski “Rule of Five”. The synthesized compounds were characterized by elemental analyses and spectral data and the compounds (4a–p) were evaluated for antimicrobial activities. Among them the compound 2-(4-hydroxybenzylidene)-N-(3-chloro-4-fluorolphenyl)hydrazinecarboxamide (4f) was found to be the most active compound that showed good antibacterial activity while the compound 2-(4-methoxybenzylidene)-N-(3-chloro-4-fluorolphenyl)hydrazinecarboxamide (4g) was moderately active against fungal strains. We have noticed that the compounds, (4f, 4k and 4d) bearing OH and NO2 groups on the phenyl ring at position 4 exhibited good antibacterial activity while compound (4g) bearing OCH3 on the phenyl ring at position 4 exhibited moderate antifungal activity.

Published
2016
Full Text
View/download PDF

27. Primary Presentation of Pulmonary Hypertension in the Peripartum

Author

John C. Caldwell, Malamo E. Countouris, Gavin Hickey, Arun Jeyabalan, and Jenifer E. Lee

Subjects
0301 basic medicine, congenital, hereditary, and neonatal diseases and abnormalities, VSD - Ventricular septal defect, Physiology, Hemodynamics, macromolecular substances, 030105 genetics & heredity, anesthesia, hemodynamics, congenital heart defect, 03 medical and health sciences, 0302 clinical medicine, pulmonary hypertension, Medicine, Diseases of the circulatory (Cardiovascular) system, cardiovascular diseases, Peripartum Cardiovascular Disease Mini-Focus Issue, Imaging Vignette: Clinical Vignette, Pregnancy, VSD, ventricular septal defect, business.industry, Hypoxia (medical), medicine.disease, ECMO - Extracorporeal membrane oxygenation, Pulmonary hypertension, RV, right ventricle, PA, pulmonary artery, RC666-701, cardiovascular system, Gestation, pregnancy, medicine.symptom, Cardiology and Cardiovascular Medicine, business, ECMO, extracorporeal membrane oxygenation, 030217 neurology & neurosurgery
Abstract

A Bosnian woman at 20 weeks’ gestation presented with dyspnea and hypoxia. She was diagnosed with Eisenmenger physiology with severe pulmonary hypertension, ventricular septal defect, and patent ductus arteriosus. Given high maternal mortality, coordination of care with a multidisciplinary team approach may allow for best possible outcomes. (Level of Difficulty: Intermediate.), Graphical abstract, A Bosnian woman at 20 weeks’ gestation presented with dyspnea and hypoxia. She was diagnosed with Eisenmenger physiology with severe pulmonary…

Published
2020

28. Microbes and agricultural waste: A safe resource for the production of bionanomaterials

Author

Anand Torvi, Jeyabalan Sangeetha, Devarajan Thangadurai, Vishal Ahuja, Arun Kashivishwanath Shettar, Shivasharana Chandrabanda Thimmappa, and Muniswamy David

Subjects
Pollution, Agricultural waste, Resource (biology), Hazardous waste, Chemistry, Agriculture, business.industry, media_common.quotation_subject, Production (economics), Biochemical engineering, business, media_common
Abstract

Nanomaterials monitor leading agricultural and environmental controlling activities especially due to its minuscule dimension. Additionally, several potential applications including a reduction in the accumulation of agricultural waste and green synthesis of nanoparticle using biological agents allow nanotechnology tools to substantially revolutionize the world. Agrowastes are ecofriendly to synthesize the typical nanostructures with precise chemical composition, morphology and size. The use of agricultural waste not only minimizes the synthesis cost but also reduces the hazardous chemicals from the environment and thus stimulates the green synthesis. Biosynthesis of various nanomaterials from agrowastes and microbes including fungi, viruses, bacteria and microalgae are being progressively explored to accomplish pollution mitigation and resource recycling objectives. This chapter highlights the synthesis mechanism of nanomaterials from microbes and agricultural wastes and their potential applications in various fields.

Published
2022
Full Text
View/download PDF

31. List of contributors

Author

Nav Raj Adhikari, Ganesh Kumar Agrawal, Niaz Ahmad, Rumana Ahmad, Fabricio Almeida Araujo, Sidra Aslam, Yıldız Aydın, Debmalya Barh, Noureddine Benkeblia, Ana Maria Benko-Iseppon, Ragini Bhardwaj, Eliseu Binneck, Milena Georgieva Bozhilova-Sakova, Marcus de Barros Braga, Tanuja Buckseth, Clarissa Challam, Ashish Kumar Choudhary, Manassés da Silva, Wilson da Silva, Sauren Das, Edian Franklin Franco De Los Santos, Kusum Dhakar, Sunny Dhir, Manmohan Dhkal, Ivona Vassileva Dimitrova, Shruti Dwivedi, Upendra N. Dwivedi, Vikas Dwivedi, Hanan Eizenberg, Sabrina Elias, José Ribamar Costa Ferreira-Neto, Shiri Freilich, Kishor Gaikwad, Rajarshi Kumar Gaur, Ranjana Gautam, Sewali Ghosh, Tijs Gilles, Archit Gupta, Kapil Gupta, Om Prakash Gupta, Ravi Gupta, Romasha Gupta, Supriya Gupta, Taslima Haque, Anjan Hazra, Md. Anowar Hossain, Niranjani Iyer, Akanksha Jaiswar, Rahul Singh Jasrotia, Tanvi Kaila, Disha Kamboj, Manjot Kaur, Parampreet Kaur, Ramandeep Kaur, Nisha Khatri, Éderson Akio Kido, Sun Tae Kim, Ashwani Kumar, Dileep Kumar, Manoj Kumar, Pradeep Kumar, Pravin Kumar, Satish Kumar, Shailesh Kumar, Ujjawal Kumar Singh Kushwaha, Stuart J. Lucas, Pradosh Mahadani, Richard Malo, Suresh Kumar Maurya, Nand Lal Meena, Vijay Singh Meena, Muhammad Aamer Mehmood, Tatiana Minkina, Chandra Nath Mishra, Habeeb Shaik Mohideen, Poonam Mor, Kunal Mukhopadhyay, Satyabrata Nanda, Priyanka Narad, Aditya Narayan, Nandakumar Natarajan, Chandranandani Negi, Chitra Nehra, Fatima Noor, Lalita Pal, Veda P. Pandey, Nikolay Manchev Petrov, Raju Poddar, Birendra Prasad, Mehboob-ur Rahman, Vishnu D. Rajput, Randeep Rakwal, Rommel Thiago Jucá Ramos, Asha Rani, Neeru S. Redhu, Narayan Rishi, Riyazuddin Riyazuddin, Zeev Ronen, Jeyabalan Sangeetha, Abhijit Sarkar, Lopamudra Satapathy, Abhishek Sengupta, Zeba Seraj, Saima Shahid, Pradeep Sharma, Priti Sharma, Swati Sharma, Imran Sheikh, Mohammad Umer Sharif Shohan, Abhishek Singh, Ajeet Singh, Anil Kumar Singh, Anuradha Singh, Dharmendra Singh, Gyanendra Pratap Singh, Nisha Singh, Rajesh K. Singh, Kevina Sonawala, Sudhanshu Srivastava, Mariya Ivanova Stoyanova, Aiman Tanveer, Zoozeal Thakur, Devarajan Thangadurai, Jagesh Kumar Tiwari, Basant K. Tiwary, Renato Hidaka Torres, Sanjaya Shankar Tripathy, Aruna Tyagi, Megha Ujinwal, Ahu Altınkut Uncuoğlu, Rakesh Kumar Verma, Pritesh Vyas, Ajit Kumar Singh Yadav, Anurag Yadav, Dinesh Yadav, Kanchan Yadav, Kusum Yadav, Manoj Kumar Yadav, Pramod Kumar Yadav, Shikha Yashveer, Raphy Zarecki, and Ezgi Çabuk Şahin

Published
2022
Full Text
View/download PDF

32. List of Contributors

Author

Bhavisha A. Bakrania, Ira M. Bernstein, Graham J. Burton, Tereza Cindrova-Davies, Marilyn J. Cipolla, Kirk P. Conrad, Sandra T. Davidge, Christianne de Groot, Ralf Dechend, Ernesto Figueiro-Filho, Susan J. Fisher, Eric M. George, Alison D. Gernand, Styliani Goulopoulou, Joey P. Granger, Kathryn J. Gray, Alisse Hauspurg, Judith U. Hibbard, Carl A. Hubel, Arun Jeyabalan, S. Ananth Karumanchi, Louise Kenny, Hannele Laivuori, Babbette LaMarca, Marshall D. Lindheimer, Eliza C. Miller, Kate Navaratnam, Alejandra E. Ontiveros, Sarosh Rana, Christopher W.G. Redman, Janet W. Rich-Edwards, Sarah A. Robertson, James M. Roberts, Sarah Schalekamp-Timmermans, Sanjeev G. Shroff, Anne Cathrine Staff, Isaac E. Stillman, Jennifer J. Stuart, Robert N. Taylor, Jason G. Umans, Manu Vatish, Kenneth Ward, Kate Wiles, and Hong Wa Yung

Published
2022
Full Text
View/download PDF

33. Contributors

Author

Kamel A. Abd-Elsalam, Hussien AboDalam, A. Anbukumaran, Syed Farooq Adil, Farah K. Ahmed, Manal M. Ahmed, Vishal Ahuja, Evidence Akhayere, Mousa A. Alghuthaymi, R.S. Anand, Mohammad Ashfaq, Marwa T. Badawy, Sri Renuakdevi Balusamy, Abdul Basit, Anindita Behera, Rami Bejjani, Bhagavanth Reddy G., Amna Chaudhry, Divya Chauhan, Parvathiraja Chelliah, Jeyapragash Danaraj, Muniswamy David, Vijay Devra, Kamal Dua, Anthony C. Ekennia, Ramya Dinesh Elangovan, Elias E. Elemike, Rachael O. Ezeani, Devaraj Ezhilarasan, M. Jeevitha, John Joseph, Nandakumar Kalarikkal, Anu Kalia, Paulkumar Kanniah, Santhiya Karuppieh, Murugan Kasi, Doga Kavaz, A. Kaviya, null Keshu, Mohamed S. Khalil, Mujeeb Khan, Yeon Ju Kim, T. Lakshmi, Bin Li, Satinder Pal Kaur Malhotra, Vamshikrishna Malyla, R.V. Mangalaraja, null Meenu, Heba I. Mohamed, Manal Mostafa, Harish Mudila, M. Nagalingam, S. Ragu Nandhakumar, Rishabh Anand Omar, Damian C. Onwudiwe, Santwana Padhi, Nandhini Palani, Vignesh Kumar Palaniswamy, Nidhi Pareek, Rajiv Periakaruppan, Haribalan Perumalsamy, Parteek Prasher, Subramanian Raghunandhakumar, Rajendran Rajakumari, S. Rajeshkumar, Chandrasekaran Rajkuberan, Rajkumar Bandi, Manviri Rani, Duraisamy Revathi, Sadia Saif, Tony Kevork Sajyan, Jeyabalan Sangeetha, Youssef Najib Sassine, Roshan Shaalan, Uma Shanker, Mousmee Sharma, D. Sheba, Arun Kashivishwanath Shettar, Sudhakar Sivasubramaniam, Nisha Elizabeth Sunny, Neetu Talreja, Devarajan Thangadurai, Emmanuel Joshua Jebasingh Sathiya Balasingh Thangapandi, Jesi Reeta Thangapandi, Lakshmi Thangavelu, Shivasharana Chandrabanda Thimmappa, Sabu Thomas, Anand Torvi, R. Usha, P. Vanathi, C.K. Venil, Sumathi Venkat, S. Venkat Kumar, Subha Priya Venkateswaran, R. Vishvanand, Vivekanand Vivekanand, Jyoti Yadav, and Monika Yadav

Published
2022
Full Text
View/download PDF

36. List of Contributors

Author

Abalos, Edgardo J., primary, Alexander, James M., additional, August, Phyllis, additional, Cipolla, Marilyn J., additional, Conde-Agudelo, Agustin, additional, Conrad, Kirk P., additional, Cunningham, F. Gary, additional, Davidge, Sandra T., additional, Dechend, Ralf, additional, De Groot, Christianne J.M., additional, Fisher, Susan J., additional, George, Eric M., additional, Granger, Joey P., additional, Hibbard, Judith U., additional, Hubel, Carl A., additional, Jeyabalan, Arun, additional, Karumanchi, S. Ananth, additional, Kenny, Louise C., additional, Lamarca, Babbette, additional, Lindheimer, Marshall D., additional, McCrae, Keith R., additional, McMaster, Michael T., additional, Ness, Roberta B., additional, Rana, Sarosh, additional, Redman, Christopher W.G., additional, Rich-Edwards, Janet W., additional, Roberts, James M., additional, Romero, Roberto, additional, Sargent, Ian L., additional, Shroff, Sanjeev G., additional, Sibai, Baha M., additional, Staff, Anne Cathrine, additional, Stillman, Isaac E., additional, Taylor, Robert N., additional, Umans, Jason G., additional, Ward, Kenneth, additional, Winn, Virginia D., additional, and Zeeman, Gerda G., additional

Published
2015
Full Text
View/download PDF

39. List of Contributors

Author

Aidukaitis, CNA, Lucas, primary, Allensworth, Jennifer L., additional, Andallu, B., additional, Aqil, Farrukh, additional, Arora, Vipin, additional, Aziz, MD, Khaled, additional, Baba, Yasutaka, additional, Bae, Yun-Jung, additional, Baveja, Ankita, additional, Bisoffi, Marco, additional, Burky, Robert, additional, Bynum, David, additional, Calaf, Gloria M., additional, Canuto, MD, Rosa A., additional, Catalano, MD, Maria G., additional, Chakraborty, Kanishka, additional, Chen, Yin-Chiu, additional, Chen, Rong-Jane, additional, Chi, Chin-Wen, additional, Chopra, Kanwaljit, additional, Coccia, Raffaella, additional, Cohen, Joshua, additional, Cruz, Ana, additional, Das, Sreemanti, additional, Datta, Palika, additional, Del Bo’, Cristian, additional, Devi, Gayathri R., additional, Evans, MD, Myron K., additional, Fadda, Maurizio, additional, Fajardo, Alexandra M., additional, Farias-Eisner, Robin, additional, Finocchiaro, Concetta, additional, Foppoli, Cesira, additional, Georgakilas, Alexandros G., additional, Gilaberte, Yolanda, additional, Gonzalez, Salvador, additional, Goya, Luis, additional, Gupta, Ramesh C., additional, Hamilton, Chris, additional, Hatzi, Vasiliki I., additional, Hayashi, Sadao, additional, Hummel, Charles, additional, Jeyabalan, Jeyaprakash, additional, Joshi, Thwisha, additional, Joshua Loke, Wei Sheng, additional, Juarranz, Angeles, additional, Kang, Daehee, additional, Khuda-Bukhsh, Anisur Rahman, additional, Krishnan, Koyamangalath, additional, Kuhad, Anurag, additional, Lee, Sang-Ah, additional, Lewis, Craig R., additional, Lim, Mann Ying, additional, Liu, Pingguo, additional, Maggiora, Marina, additional, Martin, Olga A., additional, Martín, María Angeles, additional, Mehrotra, Sudhir, additional, Munagala, Radha, additional, Muzio, Giuliana, additional, Naito, Seiji, additional, Nakajo, Masayuki, additional, Nishizawa, Toshihiro, additional, Nowsheen, Somaira, additional, O’Neill, Kim, additional, Olas, Beata, additional, Parrado, Concepción, additional, Perluigi, Marzia, additional, Philips, Neena, additional, Pramanik, Kartick C., additional, Rajeshwari, C.U., additional, Ramos, Sonia, additional, Ramsauer, Victoria Palau, additional, Riso, Patrizia, additional, Robison, Richard, additional, Sachdeva, Anand Kamal, additional, Saha, Santu Kumar, additional, Sauer, Scott J., additional, Schena, Marina, additional, Shiota, Masaki, additional, Shobha, R.I., additional, Singh, Inder P., additional, Singh, Prathistha, additional, Siomyk, Halyna, additional, Siva, Shankar, additional, Sonoda, Shunro, additional, Srivastava, Sanjay K., additional, Stone, William, additional, Sung, Mi-Kyung, additional, Sung, Ming-Ta, additional, Suzuki, Hidekazu, additional, Thomas, Paul S., additional, Tosuji, Nanako, additional, Vendrame, Stefano, additional, Wang, Ying-Jan, additional, White, Matthew, additional, and Yokomizo, Akira, additional

Published
2014
Full Text
View/download PDF

41. Nanomaterials for decontamination of organophosphorus compounds in soil

Author

Devarajan Thangadurai, Jeyabalan Sangeetha, Charles Oluwaseun Adetunji, Saher Islam, Abdel Rahman Al-Tawaha, and Arun Kashivishwanath Shettar

Subjects
Pollutant, Bioremediation, Waste management, Environmental science, Human decontamination, Agricultural pesticides, Contamination, Energy source, Groundwater
Abstract

A challenging task for the 21st century is the cleaning up environmental contaminants using ecofriendly, economical, adoptable, and sustainable technologies. Organophosphorus (OP) compounds are mostly disseminated as agricultural pesticides and plasticizers which has led to environmental accumulation, water and soil toxicity, and they are involved in many poisoning cases every year around the globe. Therefore OP residues are in top of the list for environmental bioremediation. Thus an effective and safe detoxicant therapy is needed. In the bioremediation method, several cyanobacteria, fungi, bacteria, and their enzymes with the potential to degrade OP compounds use OP as an energy source; they have been isolated and efficaciously used for environmental bioremediation in different parts of globe. Nanotechnology is a rapidly growing field of study due to its efficient mechanisms, cost-effectiveness, and environment-friendly approach in comparison to other existing treatments for the bioremediation of environmental contaminants. It makes use of several nanomaterials for the removal of pollutants from soil and groundwater through adsorption, photocatalysis, and encapsulation mode of actions.

Published
2021
Full Text
View/download PDF

42. Nanobubble technology for remediation of metal-contaminated soil

Author

Abdel Rahman Al-Tawaha, Devarajan Thangadurai, Arun Kashivishwanath Shettar, Saher Islam, Charles Oluwaseun Adetunji, and Jeyabalan Sangeetha

Subjects
Environmental remediation, business.industry, Environmental engineering, chemistry.chemical_element, Sewage, Contamination, Soil quality, Soil contamination, Mercury (element), Phytoremediation, chemistry, Environmental science, business, Effluent
Abstract

Environment contamination because of heavy metals is not only restricted to the aquatic ecosystem, even soil is also increasingly getting contaminated. In consideration with toxic metals sources for soil contamination; the most significant anthropogenic sources include effluents from industrial activities and sewage from domestic and industrial sources. In recent days several strategies are being opted to control soil contamination include physical, chemical, microbial, and phytoremediation. Heavy metals that contaminate soil include lead, arsenic, mercury, and chromium. To overcome this, recently researchers have developed advanced and efficient nanobubble technology, which means small bubbles with diameter less than 1 μm, that is, in the nanoscale. Several methods have been optimized for the generation of nanobubbles such as cavitation, hydrodynamic, acoustic, sonication, and agitation methods. This nanobubble technology has made great breakthroughs and its small size makes nanobubbles have different physicochemical and fluid dynamic properties than ordinary macrobubbles. The presence of oxygen content in nanobubbles makes them more efficient for use in several applications related to sterilization, oxidation, and to improve the soil quality. Several properties such as the presence of large area, high concentration, and the higher stability with a hydrophobic nature make nanobubbles efficient and strong in the remediation process. Apart from that these nanobubbles can easily adsorb and aggregate the dispersed particles, making the remediation process stable and effective.

Published
2021
Full Text
View/download PDF

43. Nanosensors for detection and evaluation of organic compounds in soil

Author

Charles Oluwaseun Adetunji, Arun Kashivishwanath Shettar, Jeyabalan Sangeetha, Abdel Rahman Al-Tawaha, Devarajan Thangadurai, and Saher Islam

Subjects
Pollutant, Nanosensor, Agriculture, business.industry, Sustainable agriculture, Environmental engineering, Environmental science, Soil solution, Soil fertility, Contamination, business, Soil quality
Abstract

Soil organic compounds are one of the major indicators for soil fertility. Decreased content of soil organic compounds usually implies a decline in soil quality. Therefore detection and measurement of soil organic compounds is very important. In recent years, nanosensors have been getting much attention due to their use in many industrial, medical, agricultural and environmental applications. Nanosensors are nanoscale devices that work on the principle of measuring the physical quantity and converting it into detectable signals which further can be analyzed. Nanosensors applications have transformed the conventional agricultural practices in the smart agriculture system that is a more environment-friendly strategy and energy efficient approach for sustainable agriculture. Nanosensors are being synthesized in laboratory conditions with potential to monitor temperature and seasonal changes in the soil system. In the case of detection of pollutants, soil solution treated with nanosensors gives accurate results for the measurement and detection of organic pollutants. Real-time monitoring of soil through nanosensors has reduced the excessive mounts of fertilizers and pesticides being used, thus helping to avoid the product cost and ecological contamination. Development of such nanosensors continues to play a significant part in agricultural advancements. Different types of nanosensors have been developed by employing several fabrication approaches to monitor the soil condition and measurement of organic compounds.

Published
2021
Full Text
View/download PDF

44. List of contributors

Author

Charles Oluwaseun Adetunji, Vincent Adimula, Muhammad Arif Ali, Abdel Rahman Mohammad Said Al-Tawaha, Pérez-Moreno Andrea, Muhammad Arshad, Kantha D. Arunachalam, Luqmon Azeez, Burera Khush Bakht, Asli Baysal, Adeli Beatriz Braun, Manoj Chaudhary, Osama M. Darwesh, Chinmaya Kumar Das, Valle-García Jessica Denisse, Mohammed Junaid Hussain Dowlath, Fernández-Luqueño Fabián, Prabhu Govindasamy, Amir-Ali Khalil Gul, Iram Gul, P.S. Harikumar, Pérez-Hernández Hermes, Mahnoor Iftikhar, Saher Islam, C. Jaseela, D. Arockia Jency, K. Jesitha, Sathish Kumar Karuppannan, Masoomeh Abassi Khalaki, Anup Kumar, Sonu Kumar Mahawer, Hamdy A.B. Matter, Ibrahim A. Matter, Tatiana M. Minkina, Mehdi Moameri, Arif Ali Baig Moghal, Syed Abu Sayeed Mohammed, Dinesh Mohan, Tuan Anh Nguyen, Clement Oluseye Ogunkunle, Hussein Kehinde Okoro, Stephen Oyedeji, V. Poornima Parvathi, Manvendra Patel, Torres-Gómez Andrés Patricio, Charles U. Pittman, Mahendra Prasad, Tej Pratap, Vishnu D. Rajput, Srinivasan Ramakrishnan, Sarabia-Castillo Cesar Roberto, Jeyabalan Sangeetha, Hasan Saygin, Ghulam Mujtaba Shah, Arun Kashivishwanath Shettar, Ajeet Singh, Nakshatra Bahadur Singh, Vipin K. Singh, Rajadesingu Suriyaprakash, Svetlana Sushkova, Devarajan Thangadurai, Antônio Thomé, Adan William da Silva Trentin, M. Umadevi, Caroline Visentin, and Maryam Zahedifar

Published
2021
Full Text
View/download PDF

45. Rituximab in adult minimal change disease and focal segmental glomerulosclerosis - What is known and what is still unknown?

Author

Gauckler, Philipp, Il Shin, Jae, Alberici, Federico, Audard, Vincent, Bruchfeld, Annette, Busch, Martin, Cheung, Chee Kay, Crnogorac, Matija, Delbarba, Elisa, Eller, Kathrin, Faguer, Stanislas, Galesic, Kresimir, Griffin, Sian, Hruskova, Zdenka, Jeyabalan, Anushya, Karras, Alexandre, King, Catherine, Kohli, Harbir Singh, Maas, Rutger, Mayer, Gert, Moiseev, Sergey, Muto, Masahiro, Odler, Balazs, Pepper, Ruth J., Quintana, Luis F., Radhakrishnan, Jai, Ramachandran, Raja, Salama, Alan D., Segelmark, Marten, Tesar, Vladimir, Wetzels, Jack, Willcocks, Lisa, Windpessl, Martin, Zand, Ladan, Zonozi, Reza, Kronbichler, Andreas, Gauckler, Philipp, Il Shin, Jae, Alberici, Federico, Audard, Vincent, Bruchfeld, Annette, Busch, Martin, Cheung, Chee Kay, Crnogorac, Matija, Delbarba, Elisa, Eller, Kathrin, Faguer, Stanislas, Galesic, Kresimir, Griffin, Sian, Hruskova, Zdenka, Jeyabalan, Anushya, Karras, Alexandre, King, Catherine, Kohli, Harbir Singh, Maas, Rutger, Mayer, Gert, Moiseev, Sergey, Muto, Masahiro, Odler, Balazs, Pepper, Ruth J., Quintana, Luis F., Radhakrishnan, Jai, Ramachandran, Raja, Salama, Alan D., Segelmark, Marten, Tesar, Vladimir, Wetzels, Jack, Willcocks, Lisa, Windpessl, Martin, Zand, Ladan, Zonozi, Reza, and Kronbichler, Andreas

Abstract

Primary forms of minimal change disease and focal segmental glomerulosclerosis are rare podocytopathies and clinically characterized by nephrotic syndrome. Glucocorticoids are the cornerstone of the initial immunosuppressive treatment in these two entities. Especially among adults with minimal change disease or focal segmental glomerulosclerosis, relapses, steroid dependence or resistance are common and necessitate re-initiation of steroids and other immunosuppressants. Effective steroid-sparing therapies and introduction of less toxic immunosuppressive agents are urgently needed to reduce undesirable side effects, in particular for patients whose disease course is complex. Rituximab, a B cell depleting monoclonal antibody, is increasingly used off-label in these circumstances, despite a low level of evidence for adult patients. Hence, critical questions concerning drug-safety, long-term efficacy and the optimal regimen for rituximab-treatment remain unanswered. Evidence in the form of large, multicenter studies and randomized controlled trials are urgently needed to overcome these limitations.

Published
2020
Full Text
View/download PDF

46. Contributors

Author

Abaterusso, Cataldo, primary, Ahern, Stéphane P., additional, Aisa, Maria Cristina, additional, Albright, Robert C., additional, Alfaro, Vicente, additional, Al-Khafaji, Ali, additional, Allo, Jean-Christophe, additional, Amerling, Richard, additional, Amore, Alessandro, additional, Anderson, Robert J., additional, Andreucci, Michele, additional, Andreucci, Vittorio E., additional, Andrikos, Emilios, additional, Arroyo, Vicente, additional, Arthur, John M., additional, Ash, Stephen R., additional, Assanelli, Emilio, additional, Aucella, Filippo, additional, Bagshaw, Sean M., additional, Balafa, Olga, additional, Balbi, André Luís, additional, Baldwin, Ian, additional, Ballestri, Marco, additional, Bargman, Joanne M., additional, Barletta, Gina-Marie, additional, Barletta, Jeffrey F., additional, Barozzi, Libero, additional, Barsoum, Rashad S., additional, Beaulieu, Monica, additional, Beer-Stolz, Donna, additional, Bellomo, Rinaldo, additional, Bernardo, Jose, additional, Bertolotto, Michele, additional, Bestoso, John T., additional, Betro, Gerard A., additional, Bhattacharya, Mallar, additional, Bihl, Geoffrey R., additional, Blot, Stijn I., additional, Boer, Willem, additional, Boim, Mirian A., additional, Bonello, Monica, additional, Bonventre, Joseph V., additional, Booth, A.D., additional, Bourke, Edmund, additional, Braitberg, George, additional, Brancaccio, Diego, additional, Brendolan, Alessandra, additional, Brezzi, Brigida, additional, Brodie, James C., additional, Brophy, Patrick D., additional, Brown, Ryan, additional, Bucala, Richard, additional, Buckmaster, Jonathan, additional, Budisavljevic, Milos N., additional, Bunchman, Timothy E., additional, Burdmann, Emmanuel A., additional, Bussolati, Benedetta, additional, Butkus, Matthew A., additional, Buzzelli, Daniela, additional, Calzavacca, Paolo, additional, Camussi, Giovanni, additional, Canaud, Bernard, additional, Cano, Noël J.M., additional, Cantaluppi, Vincenzo, additional, Capasso, Giovambattista, additional, Cappelli, Gianni, additional, Carlesso, Eleonora, additional, Casino, Francesco G., additional, Castillo, Leticia, additional, Cerutti, Roberta, additional, Chawla, Lakhmir S., additional, Chionh, Chang Yin, additional, Chiu, Alexander, additional, Chow, May T., additional, Chugh, Kirpal S., additional, Cianciaruso, Bruno, additional, Cignarelli, Mauro, additional, Claessens, Yann-Erick, additional, Clark, John A., additional, Clark, William R., additional, Cohen, David J., additional, Cohen, Scott D., additional, Constable, Peter, additional, Coppo, Rosanna, additional, Corey, Howard E., additional, Cozzolino, Mario, additional, Craig, Maureen, additional, Cramer, Carl H., additional, Crandall, Mark, additional, Cravedi, Paolo, additional, Crepaldi, Carlo, additional, Crew, R. John, additional, Cronin, Donald F., additional, Cruz, Dinna N., additional, Canton, Antonio Dal, additional, Dan, Maurizio, additional, D'Angelo, Angela, additional, Davenport, Andrew, additional, Davies, Andrew R., additional, Dear, James W., additional, Gasperi, Andrea De, additional, Dell'Aquila, Roberto, additional, Rocca, Giorgio Della, additional, Prete, Dorella Del, additional, Delude, Russell L., additional, Depner, Thomas, additional, Derchi, Lorenzo E., additional, Devarajan, Prasad, additional, Waele, Jan J. De, additional, Dhainaut, Jean-François, additional, Diaz-Buxo, José A., additional, Micco, Lucia Di, additional, Divino-Filho, José Carolina, additional, Doernberg, Sarah, additional, Doig, Gordon S., additional, Dries, David J., additional, Drudi, Francesco Maria, additional, Druml, Wilfred, additional, Duke, Graeme, additional, Durward, Andrew, additional, Egi, Moritoki, additional, Esposito, Ciro, additional, Evenepoel, Pieter, additional, Faga, Teresa, additional, Fan, Sheung Tat, additional, Feinfeld, Donald A., additional, Féraille, Eric, additional, Fernández, Javier, additional, Finfer, Simon, additional, Fink, Mitchell P., additional, Finkel, Kevin W., additional, Flessner, Michael F., additional, Formica, Marco, additional, Forni, Lui G., additional, Fortenberry, James D., additional, French, Craig, additional, Fumagalli, Roberto, additional, Furlanut, Mario, additional, Fute, Micheline Djouguela, additional, Gabriel, Daniela Ponce, additional, Galassi, Andrea, additional, Galbusera, Miriam, additional, Galli, Francesco, additional, Galli, Giovanni, additional, Gallieni, Maurizio, additional, Gallo, Giampiero, additional, Gambaro, Giovanni, additional, Gammill, Hilary S., additional, Gangemi, Ezio Nicola, additional, Gao, Dayong, additional, Garwood, Susan, additional, Garzotto, Francesco, additional, Gatti, Antonietta M., additional, Gattinoni, Luciano, additional, Geibel, John P., additional, George, Stephen, additional, Gesualdo, Loreto, additional, Gibney, R.T. Noel, additional, Gipson, Debbie S., additional, Glezerman, Ilya G., additional, Glorieux, Griet, additional, Goldstein, Stuart L., additional, Golper, Thomas A., additional, Gowrishankar, Manjula, additional, Grandi, Fabio, additional, Gregoretti, Cesare, additional, Grinnell, Brian W., additional, Groeneveld, A.B. Johan, additional, Gruber, Steven J., additional, Guadagni, Gualtiero, additional, Gunnerson, Kyle J., additional, Gupta, Akanksha, additional, Gura, Victor, additional, Guzzo, Isabella, additional, Hackbarth, Richard, additional, Halperin, Mitchell L., additional, Harbord, Nikolas, additional, Haymann, Jean-Philippe, additional, Heffner, Alan C., additional, Hennessy, Anthony J., additional, Heyman, Samuel N., additional, Hill, Graham L., additional, Hilton, Philip J., additional, Himmelfarb, Jonathan, additional, Hirasawa, Hiroyuki, additional, Hoenich, Nicholas A., additional, Holdsworth, Stephen R., additional, Holley, Anthony, additional, Honoré, Patrick M., additional, Hoste, Eric A.J., additional, House, Andrew A., additional, Huang, David T., additional, Huang, Zhongping, additional, Hubmayr, Rolf D., additional, Hughes, Alun D., additional, Humes, H. David, additional, Ikizler, T. Alp, additional, Imberti, Barbara, additional, Ing, Todd S., additional, Jaber, Bertrand L., additional, Janvier, Gérard, additional, Jeyabalan, Arundhathi, additional, Jha, Vivekanand, additional, Joannes-Boyau, Olivier, additional, Joannidis, Michael, additional, Jones, Daryl A., additional, Jörres, Achim, additional, Kamel, Kamel S., additional, Kamp, Ryan C., additional, Kannan, Neeta, additional, Kaplan, Lewis J., additional, Karacan, Özgür, additional, Karajala-Subramanyam, Vijay, additional, Kaushal, Gur P., additional, Kellum, John A., additional, Kemper, Markus J., additional, Khan, Asjad, additional, Khanna, Ramesh, additional, Kher, Vijay, additional, Kimmel, Paul L., additional, Kindgen-Milles, Detlef, additional, Kitching, A. Richard, additional, Kjellstrand, Carl M., additional, Kohn, Orly F., additional, Kooienga, Laura A., additional, Kooman, Jeroen P., additional, Kotanko, Peter, additional, Krediet, Raymond T., additional, Kroon, A.A., additional, Kuang, Dingwei, additional, Kuhlmann, Martin K., additional, Kuiper, Jan Willem, additional, Lam, Man-Fai, additional, Lamacchia, Olga, additional, Lameire, Norbert, additional, Langenberg, Christoph, additional, Lauri, Gianfranco, additional, Leblanc, Martine, additional, Ledebo, Ingrid, additional, Lentini, Paolo, additional, Leonard, Edward F., additional, Letteri, Jeffrey J., additional, Leunissen, Karel M., additional, Leverve, Xavier M., additional, Levin, Adeera, additional, Leypoldt, John K., additional, Liangos, Orfeas, additional, Licari, Elisa, additional, Lieberthal, Wilfred, additional, Linden, Peter K., additional, Lipman, Jeffrey, additional, Liu, Kathleen D., additional, Liu, Shiguang, additional, Livigni, Sergio, additional, Lo, Wai-Kei, additional, Lugano, Manuela, additional, Lui, Sing-Leung, additional, Lupo, Antonio, additional, Luyckx, Valerie A., additional, Macias, William L., additional, Madden, Nicholas, additional, Madore, François, additional, Majors, Daniel S., additional, Mancini, Elena, additional, Mangione, Filippo, additional, Mankad, Sunil, additional, Manzini, Pier Paolo, additional, Marangella, Martino, additional, Marenzi, Giancarlo, additional, Mariano, Filippo, additional, Marik, Paul E., additional, Marini, John J., additional, Marquis, François, additional, Marshall, John C., additional, Marshall, Mark R., additional, Mathew, Roy, additional, Matsuda, Kenichi, additional, Matthay, Michael A., additional, Maxvold, Norma J., additional, May, Clive N., additional, McCauley, Jerry, additional, McCunn, Maureen, additional, McKenna, Joseph, additional, Mehta, Ravindra L., additional, Mele, Caterina, additional, Merouani, Aicha, additional, Mesnard, Laurent, additional, Messa, Piergiorgio, additional, Metnitz, Philipp G.H., additional, Misra, Madhukar, additional, Mitzner, Steffen R., additional, Mizock, Barry A., additional, Mokhlesi, Babak, additional, Molitoris, Bruce A., additional, Morelli, Andrea, additional, Morgan, Thomas John, additional, Morigi, Marina, additional, Mount, Peter, additional, Mucelli, Roberto Pozzi, additional, Mueller, Bruce A., additional, Murray, Patrick, additional, Murugan, Raghavan, additional, Nakamura, Masataka, additional, Nalesso, Federico, additional, Nester, Carla M., additional, Nissenson, Allen, additional, Nolph, Karl, additional, Ocampo, Catalina, additional, Oda, Shigeto, additional, Okusa, Mark D., additional, Opal, Steven M., additional, Opdam, Helen, additional, Osswald, Hartmut, additional, Straaten, Heleen M. Oudemans–van, additional, Padalino, Massimo A., additional, Paden, Matthew L., additional, Paganini, Emil P., additional, Palevsky, Paul M., additional, Panat, Mani John, additional, Paolini, Francesco, additional, Parikh, Dipen, additional, Patroniti, Nicolò, additional, Pavlica, Pietro, additional, de La Garanderie, Didier Payen, additional, Pea, Federico, additional, Peng, Zhiyong, additional, Perazella, Mark A., additional, Perego, Angelo F., additional, Pereira, Estela Regina, additional, Pérez, Evans R. Fernández, additional, Perico, Norberto, additional, Pertica, Nicoletta, additional, Pertosa, Giovanni, additional, Peruzzi, Licia, additional, Petras, Dimitris, additional, Pham, Phuong-Chi, additional, Pham, Phuong-Thu, additional, Phoon, Richard K.S., additional, Picca, Stefano, additional, Piccinni, Pasquale, additional, Pinsk, Maury N., additional, Pinsky, Michael R., additional, Piroddi, Marta, additional, Plamondon, Isabelle, additional, Plank, Lindsay D., additional, Plötz, Frans B., additional, Poghosyan, Lusine, additional, Polanco, Natalia, additional, Polanco, Patricio M., additional, Polaschegg, Hans Dietrich, additional, Ponikvar, Rafael, additional, Porecca, Silvia, additional, Portilla, Didier, additional, Powell, T. Brian, additional, Quigley, Raymond, additional, Rabb, Hamid, additional, Ragaller, Maximilian, additional, Rampino, Teresa, additional, Ranpuria, Reena, additional, Rastogi, Anjay, additional, Ratanarat, Ranistha, additional, Raza, Naem, additional, Reade, Michael C., additional, Reeves, John H., additional, Reiter, Karl, additional, Remuzzi, Giuseppe, additional, Ricci, Zaccaria, additional, Ricksten, Sven-Erik, additional, Ridel, Christophe, additional, Rifai, Kinan, additional, Ring, Troels, additional, Riopel, Julie, additional, Rocha, Eduardo, additional, Roessler, Eric, additional, Rona, Roberto, additional, Ronco, Claudio, additional, Rondeau, Eric, additional, Rosen, Seymour, additional, Rosenberger, Christian, additional, Rowan, Shane, additional, Roy, Thomas, additional, Saab, Georges, additional, Sadahiro, Tomohito, additional, Sala, Carla, additional, Sala, Chiara, additional, Salama, Alan D., additional, Salmon, Adrian, additional, Salvatori, Gabriela, additional, Sam, Ramin, additional, Sandoval, Ruben M., additional, Santoro, Antonio, additional, Saotome, Takao, additional, Sappington, Penny L., additional, Sarma, J. Vidya, additional, Savige, Judy, additional, Schena, Francesco Paolo, additional, Schepers, Eva, additional, Schetz, Miet, additional, Schmidt, Gregory A., additional, Schor, Nestor, additional, Schusterschitz, Nicola, additional, Segoloni, Giuseppe, additional, Shah, Nirva, additional, Shah, Shamik H., additional, Shah, Sudhir V., additional, Sharfuddin, Asif A., additional, Shaw, Andrew, additional, Shiga, Hidetoshi, additional, Shoji, Hisataka, additional, Shukla, Ashutosh, additional, Simpson, Fiona, additional, Singbartl, Kai, additional, Singer, Mervyn, additional, Solez, Kim, additional, Sowinski, Kevin M., additional, Stafford-Smith, Mark, additional, Stange, Jan, additional, Stefanelli, Luca, additional, Stein, Deborah M., additional, Stella, Maurizio, additional, Stellin, Giovanni, additional, Story, David A., additional, Subramanian, Sanjay, additional, Swärd, Kristina, additional, Symons, Jordan M., additional, Tai, Kian Bun, additional, Tattersall, James, additional, Tedeschi, Luisa, additional, Teitelbaum, Isaac, additional, Teixeira, Vicente P. Castro, additional, Tetta, Ciro, additional, Thakar, Charuhas V., additional, Theilen, Hermann, additional, Thomas, Karl W., additional, Tolwani, Ashita, additional, Trepiccione, Francesco, additional, Triolo, Giorgio, additional, Tsang, Jennifer L.Y., additional, Tutal, Emre, additional, Uchino, Shigehiko, additional, Unruh, Mark, additional, Vail, G. Matthew, additional, Valentino, Massimo, additional, Vallon, Volker, additional, Van Biesen, Wim, additional, van der Sande, Frank M., additional, Vandijck, Dominique M., additional, Vanholder, Raymond, additional, Varghese, Sanju A., additional, Venkataraman, Ramesh, additional, Venkatesh, Bala, additional, Verbine, Anton, additional, Vincent, Jean-Louis, additional, Vinsonneau, Christophe, additional, Visvanathan, Ravindran, additional, Voinescu, Alexandra, additional, Walters, Scott, additional, Wan, Li, additional, Ward, Peter A., additional, Ward, Richard A., additional, Warrillow, Stephen, additional, Webb, Steve, additional, Whitlow, Kenneth Scott, additional, Wieslander, Anders, additional, Wilkinson, Alan H., additional, Wille, Keith, additional, Winchester, James Frank, additional, Wu, Christine, additional, Yassin, James, additional, Yeun, Jane Y., additional, Yip, Terence Pok-Siu, additional, Yu, Alex W., additional, Zacchia, Miriam, additional, Zaida, Najam, additional, Zamperetti, Nereo, additional, Zappitelli, Michael, additional, and Zarbock, Alexander, additional

Published
2009
Full Text
View/download PDF

48. Creating biobanks in low and middle-income countries to improve knowledge – The PREPARE initiative

Author

De Oliveira, Leandro, Dias, Marcos Augusto Bastos, Jeyabalan, Arundhanthi, Payne, Beth, Redman, Christopher W., Magee, Laura, Poston, Lucilla, Chappell, Lucy, Seed, Paul, von Dadelszen, Peter, Roberts, James Michael, Universidade Estadual Paulista (Unesp), Fernandes Figueira Inst, Univ Pittsburgh, BC Childrens Hosp Res, Univ British Columbia, Univ Oxford, Univ London, Kings Coll London, and St Thomas Hosp

Subjects
Maternal mortality, Adult, Prenatal Care, Article, Pre-Eclampsia, Pregnancy, Research Design, Humans, Female, Maternal Health Services, Pregnancy Trimesters, Pre-eclampsia, Developing Countries, Biomarkers, Biobank, Biological Specimen Banks
Abstract

Highlights • Low and middle-income (LMIC) countries still suffer with pre-eclampsia. • Risk assessment of pre-eclampsia has evolved in high-income countries. • Biobanks can provide a unique opportunity to understand preeclampsia in LMIC. • Databanks can provide a unique opportunity to understand preeclampsia in LMIC., The Millennium Development Goal 5, a project signed in 2000, intended to improve maternal health and reduce maternal mortality by 75% by 2015. Despite all efforts, little progress has been achieved in low and middle-income countries (LMIC) and 99% of all maternal deaths related to pre-eclampsia (PE) still occur in these settings. It is important to determine whether women in LMIC, where PE carries a greater risk than in high-income countries (HIC), have unique risk factors. Some variances may alter the risk, severity and pertinent pathophysiology of PE. We posit based upon this, that women from LMIC may have biomarkers specific to this population. Discovering such specific biomarkers and testing the relevance of biomarkers developed in high-income populations could increase the clinical usefulness of these analyses without increasing cost-effective approaches for prediction of PE. Here we briefly describe our platform to develop the PREPARE – Biobank in tertiary hospitals or basic units for antenatal care from 6 different cities in Brazil. The PREPARE – Biobank has been developed with two arms. The first arm is a cross-sectional study that will collect clinical information and biosamples from more than 1000 women who developed preterm PE. The second arm is a cohort study of 7000 women. It will collect clinical information and longitudinal biosamples from women at three times during pregnancy

Published
2018
Full Text
View/download PDF

49. Contributors

Author

Robert C. Albright, Richard Amerling, Paolo Angeli, Maria Lucia Angelotti, Massimo Antonelli, Riccardo Antoniotti, Nishkantha Arulkumaran, Pierre Asfar, Stephen R. Ash, Filippo Aucella, Francesco Aucella, Samuele Ave, Sean M. Bagshaw, Vasanthi Balaraman, Ian Baldwin, Joanne M. Bargman, Gina-Marie Barletta, Jeffrey F. Barletta, Shriganesh R. Barnela, Hülya Bayır, Monica Beaulieu, Antonio Bellasi, Rinaldo Bellomo, François Beloncle, Arjun Bhansali, Azra Bihorac, Frederic T. Billings, Horst-Walter Birk, Luis Ignacio Bonilla-Reséndiz, Josée Bouchard, Edmund Bourke, George Braitberg, Alessandra Brendolan, Alessandra Brocca, Patrick D. Brophy, Richard Bucala, Timothy E. Bunchman, Emmanuel A. Burdmann, Laurence W. Busse, Renato Antunes Caires, Pietro Caironi, Roberta Camilla, Israel Campos, Bernard Canaud, Vincenzo Cantaluppi, Maria P. Martinez, Giovambattista Capasso, Joseph A. Carcillo, Eleonora Carlesso, Francesco G. Casino, Giuseppe Castellano, Matteo Catania, Kelly A. Cawcutt, Jorge Cerda, Elliot Charen, Lakhmir S. Chawla, Stefano Chiaramonte, Horng-Ruey Chua, Bruno Cianciaruso, Paola Ciceri, Jacek Cieslak, William R. Clark, Rolando Claure-Del Granado, Anna Clementi, Ivan N. Co, Fernanda Oliveira Coelho, Ferruccio Conte, Howard E. Corey, Laura Cosmai, Elerson Carlos Costalonga, Andrea Costamagna, Maria Rosa Costanzo, Mario Cozzolino, Carl H. Cramer, Paolo Cravedi, Carlo Crepaldi, Jacques Creteur, R. John Crew, Verônica Torres da Costa e Silva, Andrew Davenport, Andrew R. Davies, Rohit D'Costa, Dawson F. Dean, Charlotte Debiais, Massimo de Cal, Paras Dedhia, Harm-Jan de Grooth, Roberto Dell'Aquila, Sergio Dellepiane, Richard Phillip Dellinger, Lucia Del Vecchio, Thomas A. Depner, Silvia De Rosa, Clifford S. Deutschman, Prasad Devarajan, A. Dewitte, Biagio R. Di Iorio, Luca Di Lullo, Lucia Di Micco, Matteo Di Nardo, Xiaoqiang Ding, Fiorella D'Ippoliti, Salvatore Di Somma, Kent Doi, David J. Dries, Wilfred Druml, Graeme Duke, Francois Durand, Michael T. Eadon, Devin Eckstein, Moritoki Egi, Somchai Eiam-Ong, Paul W.G. Elbers, Francesca Elli, Steve Elliott, David R. Emlet, Zoltan Endre, Roger G. Evans, Vito Fanelli, Fatemeh Fattahi, Christine Kinggaard Federspiel, Marcela A. Ferrada, Fiorenza Ferrari, Enrico Fiaccadori, Marco Fiorentino, Caleb Fisher, Michael F. Flessner, Marco Formica, Lui G. Forni, Claire Francoz, Craig French, Dana Y. Fuhrman, Giordano Fumagalli, Miriam Galbusera, Maurizio Gallieni, Hilary S. Gammill, Dayong Gao, Francesco Garzotto, Giuseppe Gatta, Kelly R. Genga, Simonetta Genovesi, Yuri S. Genyk, Christel Geradin, Loreto Gesualdo, Davide Giavarina, Anna Giuliani, Ilya G. Glezerman, Stuart L. Goldstein, Thomas A. Golper, Hernando Gómez, Antonio Granata, Giuseppe Grandaliano, Giacomo Grasselli, A.B. Johan Groeneveld, Philippe Guerci, Kyle J. Gunnerson, Nikolas Harbord, Lyndsay A. Harshman, Anthony J. Hennessy, Graham L. Hill, Charles Hobson, Bernd Hohenstein, Patrick M. Honoré, Edward Horwitz, Leila Hosseinian, Eric A.J. Hoste, Andrew A. House, H. David Humes, Faeq Husain-Syed, Can Ince, Todd S. Ing, Rita Jacobs, Dharmvir Jaswal, Arun Jeyabalan, Olivier Joannes-Boyau, Michael Joannidis, Emily Joyce, Sandra L. Kane-Gill, Lewis J. Kaplan, Kianoush Kashani, Nevin Katz, John A. Kellum, Ramesh Khanna, Nahmah Kim-Campbell, Joshua D. King, Christopher J. Kirwan, Joseph E. Kiss, David Klein, Peter Kotanko, Raymond T. Krediet, Martin K. Kuhlmann, Jan Willem Kuiper, Philippe Lachance, Norbert Lameire, Thomas Langer, Yugeesh R. Lankadeva, Louis-Philippe Laurin, Elena Lazzeri, Martine Leblanc, Joannie Lefebvre, Paolo Lentini, Hélène Leray-Moragués, Adeera Levin, Susie Q. Lew, Helen Liapis, Kathleen D. Liu, Sergio Livigni, Francesco Locatelli, Anna Lorenzin, Jian-Da Lu, Renhua Lu, Nicholas Lysak, Etienne Macedo, Niti Madan, François Madore, Linda L. Maerz, Matthew J. Maiden, Rakesh Malhotra, Marita Marengo, Filippo Mariano, Paul E. Marik, John J. Marini, Rossella Marino, Mark R. Marshall, Johan Mårtensson, Ryo Matsuura, Clive N. May, Patrizio Mazzone, Jerry McCauley, Peter A. McCullough, Blaithin A. McMahon, Ravindra L. Mehta, Caterina Mele, Madhav Menon, Mario Meola, Aicha Mérouani, Jean-Yves Meuwly, Paola Milla, Madhukar Misra, Paraish S. Misra, Barry A. Mizock, Jwalant R. Modi, Gilbert Moeckel, Bruce A. Molitoris, Santo Morabito, Roberto Pozzi Mucelli, Patrick T. Murray, Raghavan Murugan, Mitra K. Nadim, Devika Nair, Federico Nalesso, Mauro Neri, Trung C. Nguyen, Zhaohui Ni, Marina Noris, Tessa Novick, John C. O'Horo, Mark Douglas Okusa, Steven M. Opal, Helen Ingrid Opdam, Marlies Ostermann, Emerenziana Ottaviano, Heleen M. Oudemans-van Straaten, Christian Overgaard-Steensen, Massimo A. Padalino, Vincenzo Panichi, Priyanka Parameswaran, Samir S. Patel, Didier Payen, Federico Pea, W. Frank Peacock, Sandrica Young Peart, Sadudee Peerapornratana, Paolo Pelosi, Zhi-Yong Peng, Norberto Perico, Licia Peruzzi, Francesco Pesce, Antonio Pesenti, Ilaria Petrucci, Phuong-Chi Pham, Phuong-Thu Pham, Richard K.S. Phoon, Salvatore Piano, Michael R. Pinsky, Lise Piquilloud, Valentina Pistolesi, Lindsay D. Plank, Frans B. Plötz, Manuel Alfredo Podestá, Camillo Porta, Marco Pozzato, Michele Prencipe, John R. Prowle, Zudin A. Puthucheary, Lirong Qu, Jean-Sebastien Rachoin, Jai Radhakrishnan, V. Marco Ranieri, Ranistha Ratanarat, Giuseppe Remuzzi, Shelby Resnick, Oleksa G. Rewa, Zaccaria Ricci, Christophe Ridel, Kinan Rifai, Troels Ring, Lilia M. Rizo-Topete, Eric Roessler, Paola Romagnani, Stefano Romagnoli, Claudio Ronco, Federico Ronco, Mitchell H. Rosner, Emanuele Rossetti, James A. Russell, Georges Saab, Alice Sabatino, Sonali S. Saboo, Sara Samoni, Penny Lynn Sappington, Marco Sartori, Judy Savige, Francesco Paolo Schena, Antoine Guillaume Schneider, Pieter Schraverus, Wibke Schulte, Giuseppe Segoloni, Matthew W. Semler, Aashish Sharma, Andrew Shaw, Naitik Sheth, Ashutosh Shukla, Eric C. Siddall, Theodore M. Sievers, Edward D. Siew, Kai Singbartl, Mervyn Singer, Pooja Singh, Loren E. Smith, Sachin S. Soni, Mara Serrano Soto, Herbert D. Spapen, Nattachai Srisawat, Ajay Srivastava, Giovanni Stellin, Jordan M. Symons, Balazs Szamosfalvi, Kian Bun Tai, Unmesh V. Takalkar, Isaac Teitelbaum, Ciro Tetta, Charuhas V. Thakar, Marta Tonon, Francesco Trepiccione, Darrell Triulzi, Chopra Tushar, Shigehiko Uchino, Ali Valika, Wim Van Biesen, Wim Vandenberghe, Raymond Vanholder, Jill Vanmassenhove, Anton Verbine, Marco Vergano, Gianluca Villa, Pierre-Marc Villeneuve, Jean-Louis Vincent, Christophe Vinsonneau, Grazia Maria Virzì, Federico Visconti, Ravindran Visvanathan, Li Van Vong, Hans-Dieter Walmrath, Peter A. Ward, Matthew A. Weir, Xiaoyan Wen, Julia Wendon, James Frank Winchester, Adrian Wong, Elke L. Woodhouse, Jun Xue, Anju Yadav, Preethi Yerram, Lenar Yessayan, Jane Y. Yeun, Alex W. Yu, Marta Zaccaria, Miriam Zacchia, Teena P. Zachariah, Nereo Zamperetti, Fernando G. Zampieri, Pierluigi Zanco, Alberto Zanella, Luca Zanoli, Michael Zappitelli, Jose J. Zaragoza, Alexander Zarbock, Marta Zaroccolo, Han Zhang, and Andrea Zimmer

Published
2019
Full Text
View/download PDF

50. Sustained expression of CYPs and DNA adduct accumulation with continuous exposure to PCB126 and PCB153 through a new delivery method: Polymeric implants

Author

Hans-Joachim Lehmler, Gabriele Ludewig, Ramesh C. Gupta, Xing Xin, Jeyaprakash Jeyabalan, Farrukh Aqil, Hua Shen, and Larry W. Robertson

Subjects
Antioxidant, Health, Toxicology and Mutagenesis, medicine.medical_treatment, Oxidative phosphorylation, Toxicology, Article, Andrology, Lesion, Downregulation and upregulation, Pharmacokinetics, CYPs, lcsh:RA1190-1270, DNA adduct, medicine, lcsh:Toxicology. Poisons, chemistry.chemical_classification, PCB153 (2,2′,4,4′,5,5′-hexachlorobiphenyl), Polychlorinated biphenyls (PCBs), Lung, 32P-postlabeling, DNA adducts, Paraoxonase 1 (PON1), 3. Good health, medicine.anatomical_structure, Enzyme, chemistry, medicine.symptom, Polymeric implants, PCB126 (3,3′,4,4′,5-pentachlorobiphenyl)
Abstract

Highlights • Polymeric implants successfully achieved continuous exposure to PCBs in rats. • PCB126 resulted in significant oxidative DNA damage (8-oxodG) in rat liver and lung. • PCB126 or in combination with PCB153 induced PON1 and its activity in the liver. • The induction was even greater for PON3 and AhR gene transcription. • Co-treatment reduced mammary PCB153 and increased liver PCB126 and PCB153 levels., A new delivery method via polymeric implants was used for continuous exposure to PCBs. Female Sprague-Dawley rats received subcutaneous polymeric implants containing PCB126 (0.15% load), PCB153 (5% load), or both, for up to 45 d and release kinetics and tissue distribution were measured. PCB153 tissue levels on day 15 were readily detected in lung, liver, mammary and serum, with highest levels in the mammary tissue. PCB126 was detected only in liver and mammary tissues. However, a completely different pharmacokinetics was observed on co-exposure of PCB153 and PCB126, with a 1.8-fold higher levels of PCB153 in the liver whereas a 1.7-fold lower levels in the mammary tissue. PCB126 and PCB153 caused an increase in expression of key PCB-inducible enzymes, CYP 1A1/2 and 2B1/2, respectively. Serum and liver activities of the antioxidant enzymes, PON1 and PON3, and AhR transcription were also significantly increased by PCB126. 32P-postlabeling for polar and lipophilic DNA-adducts showed significant quantitative differences: PCB126 increased 8-oxodG, an oxidative DNA lesion, in liver and lung tissues. Adduct levels in the liver remained upregulated up to 45 d, while some lung DNA adducts declined. This is the first demonstration that continuous low-dose exposure to PCBs via implants can produce sustained tissue levels leading to the accumulation of DNA-adducts in target tissue and induction of indicator enzymes. Collectively, these data demonstrate that this exposure model is a promising tool for long-term exposure studies.

Published
2014

Catalog

Books, media, physical & digital resources
See catalog results