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5 results on '"James M. Foran"'

1. Primary peritoneal myeloid sarcoma in association with CBFB/MYH11 fusion

Author

Justin J. Kuhlman, Zaid H. Abdel Rahman, Liuyan Jiang, David M. Menke, James M. Foran, and Hemant S. Murthy

Subjects
Myeloid sarcoma, Primary peritoneal myeloid sarcoma, Inv(16), CBFB/MYH11, De novo myeloid sarcoma, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

Myeloid sarcoma, also known as chloroma or granulocytic sarcoma is an extramedullary disease process that typically presents in association with acute myeloid leukemia during initial presentation or at relapse. Often associated with cytogenetic mutations, including t(8;21)(q22;q22); RUNX1/RUNX1T1, and less frequently with inv(16)(p13.1q22) or t(16;16)(p13.1;q22); CBFB/MYH11, myeloid sarcoma is most commonly discovered in skin, soft tissue, bone, and connective tissue. In rare circumstances, myeloid sarcoma can present without any evidence of bone marrow or leukemic involvement. These cases of de novo myeloid sarcoma are rare, and are commonly misdiagnosed due to similarities with other entities. We report an unusual case of a primary de novo peritoneal myeloid sarcoma, in association with inv(16)(p13;q22) and clonal heterogeneity at different sites of involvement, that has responded well to AML induction therapy and consolidation treatment with gemtuzumab ozogamicin and high dose cytarabine. Cytogenetics, immunophenotyping, and chromosomal analysis, were each critical in establishing a proper diagnosis as well as helping to develop appropriate therapeutic strategies for this rare entity.

Published
2021
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2. Impact of hospital hospitality house programs on quality of life and mood of patients and caregivers after hematopoietic stem cell transplant

Author

Maria Emma Torres, Angelina D. Tan, Mark R. Litzow, Maria A. Stevens, Jeff A. Sloan, James M. Foran, Vivek Roy, William J. Hogan, Shahrukh K. Hashmi, Valerie Callahan, and Gerardo Colon-Otero

Subjects
Adult, Male, Pediatrics, medicine.medical_specialty, Multivariate analysis, Pilot Projects, lcsh:RC254-282, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Quality of life, Older patients, Living place, medicine, Clinical endpoint, Humans, Prospective Studies, Transplant type, Aged, business.industry, lcsh:RC633-647.5, Hematopoietic Stem Cell Transplantation, Hematology, General Medicine, lcsh:Diseases of the blood and blood-forming organs, Middle Aged, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Hospitalization, Mood, surgical procedures, operative, Oncology, Bone transplantation, Caregivers, 030220 oncology & carcinogenesis, Quality of Life, Female, business, 030215 immunology
Abstract

Objective/background: The quality of life (QOL) of hematopoietic stem cell transplant (HSCT) patients and their caregivers decreases during the first 8 days after HSCT. Methods: This prospective pilot study collected preliminary data on the impact of posttransplant living arrangements (hospital hospitality house [HHH] vs. hotel, apartment, or house [“hotel”]) and other factors on the QOL of HSCT patients and their caregivers. The predefined primary end point was QOL of patients and their caregivers on Day 30 (QOL30) as measured by the linear analog self-assessment (LASA). Results: Forty-four HSCT patients participated (HHH 23, hotel 21; allogeneic 18, autologous 26). No significant differences in QOL30 (mean LASA score) were noted between patient groups (55.6 [HHH] vs. 72.2 [hotel], p = .06) or between caregiver groups (77.8 [HHH] vs. 88.9 [hotel], p = .20). Multivariate analysis for QOL30 showed that baseline QOL (p = .006) and age (p = .049) were significant predictors of QOL30 after adjustment for sex, post-HSCT living place, and transplant type. Older patients (≥60 years) had a significantly lower QOL30 than younger patients (mean score, 51.6 vs. 75.3; p = .02). Conclusion: Efforts to improve QOL30 of HSCT patients and caregivers in the confined environment of an HHH should focus on patients with low baseline QOL and older patients. Keywords: Age, Marrow transplant, Quality of life, Stem cell transplant

Published
2019

3. Primary peritoneal myeloid sarcoma in association with CBFB/MYH11 fusion

Author

Zaid Abdel Rahman, Hemant S. Murthy, Justin J Kuhlman, Liuyan Jiang, James M. Foran, and David M. Menke

Subjects
Gemtuzumab ozogamicin, Article, 03 medical and health sciences, 0302 clinical medicine, Immunophenotyping, hemic and lymphatic diseases, medicine, MYH11, Myeloid sarcoma, Inv(16), RC254-282, De novo myeloid sarcoma, business.industry, RUNX1T1, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Myeloid leukemia, Hematology, medicine.disease, Primary peritoneal myeloid sarcoma, CBFB/MYH11, medicine.anatomical_structure, Oncology, 030220 oncology & carcinogenesis, Cancer research, Sarcoma, Bone marrow, business, 030215 immunology, medicine.drug
Abstract

Myeloid sarcoma, also known as chloroma or granulocytic sarcoma is an extramedullary disease process that typically presents in association with acute myeloid leukemia during initial presentation or at relapse. Often associated with cytogenetic mutations, including t(8;21)(q22;q22); RUNX1/RUNX1T1, and less frequently with inv(16)(p13.1q22) or t(16;16)(p13.1;q22); CBFB/MYH11, myeloid sarcoma is most commonly discovered in skin, soft tissue, bone, and connective tissue. In rare circumstances, myeloid sarcoma can present without any evidence of bone marrow or leukemic involvement. These cases of de novo myeloid sarcoma are rare, and are commonly misdiagnosed due to similarities with other entities. We report an unusual case of a primary de novo peritoneal myeloid sarcoma, in association with inv(16)(p13;q22) and clonal heterogeneity at different sites of involvement, that has responded well to AML induction therapy and consolidation treatment with gemtuzumab ozogamicin and high dose cytarabine. Cytogenetics, immunophenotyping, and chromosomal analysis, were each critical in establishing a proper diagnosis as well as helping to develop appropriate therapeutic strategies for this rare entity.

Published
2021

5. Contributors

Author

James L. Abbruzzese, Martin D. Abeloff, Ghassan K. Abou-Alfa, Janet L. Abrahm, Jeffery S. Abrams, Geza Acs, Joseph Aisner, Seena C. Aisner, Rhoda M. Alani, Steven R. Alberts, Richard F. Ambinder, Leslie A. Andritsos, Frederick R. Appelbaum, Sachin Apte, James O. Armitage, Deborah Armstrong, Mamad M. Bagheri, Charles M. Balch, Lodovico Balducci, Claudia Beghé, Robert Benjamin, Charles L. Bennett, Ross Stuart Berkowitz, Donna Bernstein, Michael R. Bishop, William J. Blot, Leslie Blumgart, Guido T. Bommer, Michael J. Borowitz, Julie R. Brahmer, Viven H.C. Bramwell, Malcom V. Brock, Ali Bydon, Mitchell S. Cairo, Dario Campana, David P. Carbone, H. Ballentine Carter, Manpreet K. Chadha, Daniel W. Chan, Alfred E. Chang, Nai-Kong V. Cheung, Michaele Christian, Michael F. Clarke, Anthony Cmelak, Peter F. Coccia, Alfred M. Cohen, Robert E. Coleman, Carolyn Compton, Linda D. Cooley, Jorge Cortes, Sara A. Courtneidge, Kenneth H. Cowan, Daniel J. Culkin, Josep Dalmau, Giulio J. D'Angio, Laura Dawson, Steven R. Deitcher, Ronald P. DeMatteo, Philip A. DeSimone, Theodore L. DeWeese, Subba R. Digumarthy, Angela Dispenzieri, Jeffrey S. Dome, John H. Donohue, James H. Doroshow, Jeffery A. Drebin, Dan G. Duda, Austin Duffy, Linda R. Duska, Mario A. Eisenberger, Rebecca L. Elstrom, Janine T. Erler, Michael S. Ewer, Eric R. Fearon, Leslie A. Fecher, Alessandro Fichera, Alexandra H. Filipovich, Karen A. Fitzner, Robert L. Foote, James M. Foran, Arlene A. Forastiere, James M. Ford, Alison G. Freifeld, Carl E. Freter, Arlan F. Fuller, Emma E. Furth, Michael C. Garofalo, Mark C. Gebhardt, N. Lynn Gerber, Manish Gharia, Amato J. Giaccia, Mark R. Gilbert, John Glaspy, Katrina Y. Glover, Ziya L. Gokaslan, Nicola Gökbuget, Donald Peter Goldstein, Adriana Gonzalez, Anne Kathryn Goodman, Ellen Gordon, Daniel M. Green, Michael R. Grever, Andrew Grigg, Louise Grochow, Thomas G. Gross, Stuart A. Grossman, Leonard L. Gunderson, Juliet Gunkel, Martin Gutierrez, Thomas M. Habermann, Barrett G. Haik, John D. Hainsworth, Dennis Hallahan, Nader N. Hanna, Eleanor E.R. Harris, Ernie Hawk, Nancy H. Heideman, Richard L. Heideman, Lee J. Helman, Jessica Hochberg, Dieter Hoelzer, Ingunn Holen, Sandra J. Horning, Kim Huang, Peter B. Illei, Elaine S. Jaffe, Sanjay B. Jagannath, Rakesh K. Jain, William Jarnagin, Anuja Jhingran, David H. Johnson, Heather Jones, Kevin D. Judy, Rosalyn A. Juergens, Jeffrey A. Kant, Hagop Kantarjian, Zeynel A. Karcioglu, Danielle M. Karyadi, Norbert Kased, Michael B. Kastan, Daniel R. Kaul, John Kawaoka, Margaret Kemeny, Nancy Kemeny, Thomas W. Kensler, Lawrence R. Kleinberg, Boris Kobrinsky, Jeanne Kowalski, Shivaani Kummar, Geeta Lal, Paul F. Lambert, Julie R. Lange, Janessa Laskin, Fred Lee, Susanna I. Lee, Jacqueline Lees, Renato Lenzi, Caryn Lerman, Allan Lipton, Charles L. Loprinzi, Gerard Lozanski, Robert Lustig, Mitchell Machtay, Amit Maity, Uzma Malik, C. Scott Manatt, John C. Mansour, Pierre P. Massion, R. Samuel Mayer, Beryl McCormick, Charles J. McDonald, Ross McDougall, W. Gillies McKenna, Steven Meranze, James M. Metz, Frank L. Meyskens, Fabrizio Michelassi, Radha Mikkilineni, Victoria Mock, Mohammed Mohiuddin, James Montie, A. Ross Morton, Anthony J. Murgo, James R. Neff, William G. Nelson, Suzanne Nesbit, John E. Niederhuber, Tracey O'Connor, Thomas O'Dorisio, Kenneth Offit, Mihaela Onciu, Eileen M. O'Reilly, Elaine A. Ostrander, Brian O'Sullivan, Drew M. Pardoll, Catherine K. Park, Freda Patterson, Steven Z. Pavletic, Michael C. Perry, LoAnn C. Peterson, Peter C. Phillips, Steven Piantadosi, Robert Pili, Peter W.T. Pisters, Mark R. Pittelkow, John P. Plastaras, Elizabeth A. Platz, Julian Pribaz, Amy A. Pruitt, Ching-Hon Pui, Joe Bill Putnam, Harry Quon, Martin N. Raber, S. Vincent Rajkumar, William F. Regine, Mark Ritter, John Robert Roberts, Leslie Robinson-Bostom, Ronald Rodriguez, Carlos Rodriguez-Galindo, Myrna Rosenfeld, Nadia Rosenthal, James L. Rubenstein, Brian P. Rubin, Reena Rupani, Valerie W. Rusch, Anthony H. Russell, Charles J. Ryan, Vergilio Sacchini, Alan B. Sandler, Howard Sandler, John T. Sandlund, Victor M. Santana, Robert A. Schnoll, Daniel M. Sciubba, Michael V. Seiden, Mikkael A. Sekeres, William H. Sharfman, Ricky A. Sharma, Kostandinos Sideras, Kenneth Silver, Eric J. Small, David C. Smith, Penny K. Sneed, Stephen N. Snow, Lori J. Sokoll, Mika A. Sovak, James L. Speyer, Alex I. Spira, Dempsey Springfield, Sheri L. Spunt, Daniel Stewart, Paul T. Strickland, Bill Sugden, Siobhan Sutcliffe, Weijing Sun, Martin S. Tallman, James E. Talmadge, Ayalew Tefferi, Peter Thom, Craig B. Thompson, Michael J. Tisdale, Kensei Tobinai, Joseph E. Tomaszewski, Suzanne L. Topalian, Frank M. Torti, Donald L. Trump, Katherine A. Vallis, Gauri R. Varadhachary, Sreenivas Vemulapalli, Kala Visvanathan, Nina D. Wagner-Johnston, Richard L. Wahl, Toshiki Watanabe, Barbara L. Weber, Sharon Weber, Ronald J. Weigel, Irving L. Weissman, William Westra, Kathleen S. Wilson, Wyndham H. Wilson, Antonio C. Wolff, Sandra L. Wong, Gary S. Wood, Lance S. Wyatt, Anaadriana Zakarija, Tal Z. Zaks, and Jason A. Zell

Published
2008

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