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1. Circulant anti-triiodothyronine antibodies in a patient with Graves' disease: effects on measurement of T3 with different RIA procedures.

Author

Rodriguez-Espinosa J, Gomez-Gerique JA, Ordoñez-Llanos J, Soldevila-Bosch J, and Concustella-Bas E

Subjects
Adult, Anilino Naphthalenesulfonates immunology, Antibodies isolation & purification, Female, Humans, Immunoglobulin G isolation & purification, Radioimmunoassay, Graves Disease immunology, Triiodothyronine immunology
Abstract

High levels of triiodothyronine have been found in a patient with Graves' disease caused by circulating antibodies able to bind specifically with serum triiodothyronine. High values found were due to the interference of the endogenous antibody with the conventional techniques of radioimmunoassay used for the evaluation of the hormone. An analytical pattern to identify these antitriiodothyronine antibodies is described.

Published
1980
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