1. An unexpected, invasive disease of the mastoid bone and external auditory canal
- Author
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Iris Krebbers, Rens M. van de Goor, Roel J.W. van Kampen, Paul H.M.H. Theunissen, and Verona E. Bergshoeff
- Subjects
Systemic mastocytosis ,Mast cell disorders ,External auditory canal ,Parotid gland ,Otorhinolaryngology ,RF1-547 - Abstract
A 65-year-old male patient with a history of Myelodysplastic Syndrome (MDS) and Systemic Mastocytosis (SM) presented with an invasive disease of the external auditory canal (EAC) and a parotid gland abscess. Abscess drainage and treatment for a malignant otitis externa (MOE) was started, which did not lead to clinical improvement. Computed Tomography (CT) of the petrous bone as well as a Positron Emission Tomography/Computed Tomography with 2-[fluorine-18]-fluoro-2-deoxy-d-glucose (FDG-PET-CT) showed bony erosion of the EAC with a symmetrical FDG distribution at the level of both EACs. Histopathological biopsies of the EAC revealed a rarely encountered localization of systemic mastocytosis (SM). Especially patients with a hematological disorder such as a MDS are at risk to develop SM. In case of a fulminant infectious disease of the EAC in these patients, a localization of SM should be considered as well. This is the first report on SM with a localization in the EAC.
- Published
- 2020
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