There are certain well-known relationships between handedness and mode of brain organization. For instance, the large majority of right-handers have speech represented in the left cerebral hemisphere; however, of the left-handed population, about two-thirds have speech represented in the left hemisphere and about one-third in the right. Furthermore, whereas right-handers tend to show a clear-cut dominance of the left hemisphere for speech, a significant proportion of left-handers have some speech represented in both cerebral hemispheres. Therefore, left-handers as a group differ from right-handers, and are also more heterogeneous than right-handers, both in terms of direction of cerebral dominance and also in terms of degree of dominance (Goodglass & Quadfasel, 1954; Hecaen & de Ajureaguerra, 1964; Hecaen & Piercy, 1956; Hecaen & Sauget, 1971; Milner, Branch, & Rasmussen, 1966; Subirana, 1969; Zangwill, 1960). Recently, interest has developed in the possibility that such neurological differences might be reflected in ability differences of various types. Thus, some investigators have argued for a relationship between leftor mixedhandedness and reading disability (Ginsburg & Hartwick, 1971; Satz & Sparrow, 1970; Shearer, 1968; Wold, 1968; Wussler & Barclay, 1970; Zurif & Carson, 1970; but see also Applebee, 1971; Hartlag & Green, 1971). Others have presented evidence that left-handers or mixed-handers perform more poorly than right-handers on visuospatial tasks (Levy, 1969; Miller, 1971; Silverman, Adevai, & McGough, 1966; but also see Newcombe & Ratliff, 1973). In both cases, explanations have been advanced in terms of a more bilateral representation of speech and related functions in the mixed or left-handed groups. The present study demonstrates that lefthanders with mixed hand preference show enhanced performance on certain auditory tasks, and it is hypothesized that this superiority also reflects a bilateral representation of function. It is further suggested that some of the discrepancies in the literature may be due to the heterogeneity of the left-handed and mixed-handed groups; and that a fourway classification of handedness based on hand used in writing and on consistency of hand preference would produce more homogeneous results.