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Your search keyword '"Dhiman, Shikha"' showing total 4 results
Start Over Author "Dhiman, Shikha" Publisher elsevier
4 results on '"Dhiman, Shikha"'

2. Contributors

Author

Abro, Rashid, primary, Adesina, Adeyemi, additional, Ahmad, Akil, additional, Ahmed, Shoaib, additional, Ahamd, Zahoor, additional, Akhter, Faheem, additional, Ali, Esfandyar, additional, Ali, Imran, additional, Anees, Muhammad, additional, Annavaram, Viswadevarayalu, additional, Awoyera, Paul O., additional, Ayub, Muhammad Ashar, additional, Babkin, Alexander V., additional, Baloch, Humair Ahmed, additional, Bandala, Erick R., additional, Banerjee, Sushmita, additional, Barua, Pranta, additional, Bhamore, Jigna R., additional, Burakov, Alexander E., additional, Burakova, Irina V., additional, Chauhan, Heena, additional, Cruz, Guilherme C.F., additional, Cueva-Sola, Ana Belen, additional, Das, Sumistha, additional, Debnath, Nitai, additional, Dhiman, Shikha, additional, Farooqi, Zia Ur Rahman, additional, Fatima, Hina, additional, Garg, Vinod Kumar, additional, Gautam, Pavan Kumar, additional, Gupta, Renuka, additional, Helal, Wasim M.K., additional, Hossain, Nazia, additional, Ibrahim, Mohamad Nasir Mohd, additional, Ikechukwu, Eberechukwu Laura, additional, Islam, Tariqul, additional, Jatoi, Abdul Sattar, additional, Jeong, Jong-Ryul, additional, John, Juliana, additional, Jorepalli, Sumalatha, additional, Jyothi, Rajesh Kumar, additional, Kailasa, Suresh Kumar, additional, Karri, Rama Rao, additional, Kataria, Navish, additional, Kayshar, Md Shahidullah, additional, Kim, Dongsoo, additional, Kırgız, Mehmet Serkan, additional, Koduru, Janardhan Reddy, additional, Kuchi, Rambabu, additional, Kumar, Jai, additional, Latif, Kashif, additional, Lee, Jin-Young, additional, Martins, Lucas G., additional, Mazari, Shaukat Ali, additional, Medina-Orendain, Daniel A., additional, Melezhik, Alexander V., additional, Memon, Abdul Qayoom, additional, Mubarak, Nabisab Mujawar, additional, Muhammad, Atta, additional, Muhammad, Riaz, additional, Nadeem, Muhammad, additional, Naeem, Asif, additional, Naz, Iffat, additional, Neskoromnaya, Elena A., additional, Nizamuddin, Sabzoi, additional, Nnaji, Chidozie Charles, additional, Othmani, Amina, additional, Padmanaban, V.C., additional, Pandey, Krishna Kumar, additional, Parhi, Pankaj Kumar, additional, Park, Tae-Jung, additional, Ramirez, Irwing, additional, Rashid, Mohd, additional, Rawat, Shalu, additional, Rehman, Abdul, additional, Zia ur Rehman, Muhammad, additional, Rizwan, Muhammad, additional, Rodríguez-Narvaez, Oscar M., additional, Sabzoi, Nizamuddin, additional, Samanta, Sintu Kumar, additional, Savu, Raluca, additional, Sehar, Shama, additional, Shabaan, Muhammad, additional, Shrestha, Bhanu, additional, Sidddiqui, MTH, additional, Simate, Geoffrey S., additional, Singh, Bharti, additional, Singh, Jiwan, additional, Singh, Megha, additional, Singh, Ved Vati, additional, Somala, Adinarayana Reddy, additional, Stanisic, Danijela, additional, Tasic, Ljubica, additional, Tkachev, Alexey G., additional, Tripathi, Manoj, additional, Ugwu, Emmanuel Ikechukwu, additional, Umair, Muhammad, additional, Umar, Wajid, additional, Villaseñor-Basulto, Deborah L., additional, Yaqoob, Asim Ali, additional, Younis, Adnan, additional, and Zia, Husnain, additional

Published
2022
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3. Immobilization of mannanase on sodium alginate-grafted-β-cyclodextrin: An easy and cost effective approach for the improvement of enzyme properties.

Author

Dhiman S, Srivastava B, Singh G, Khatri M, and Arya SK

Subjects
Adsorption, Hydrogen-Ion Concentration, Kinetics, Temperature, Alginates chemistry, Cost-Benefit Analysis, Enzymes, Immobilized chemistry, Enzymes, Immobilized metabolism, beta-Cyclodextrins chemistry, beta-Mannosidase chemistry, beta-Mannosidase metabolism
Abstract

Partially purified β-mannanase was immobilized on the modified matrix of sodium alginate-grafted-β-cyclodextrin. The Fourier-transform infrared spectroscopy (FTIR) and X-ray diffraction characterization proved that β-cyclodextrin (β-CD) was successfully grafted with sodium alginate. After successful immobilization, yield of enzyme was found 91.5%, pH and temperature optima were increased, 6.0 to 7.0 and 50 °C to 55 °C respectively. Immobilized mannanase was able to reuse 15 times and retained its 70% activity, meanwhile the immobilized enzyme showed 60% activity after 30 days of storage at 4 °C. Immobilization also increased the thermostability and half-life of the enzyme when compared to the free mannanase. During the comparison of adsorption isotherm and kinetic models, Langmuir isotherm and pseudo-first order kinetics were observed to be the best fit model for the confirmation of immobilization., Competing Interests: Declaration of competing interest The authors with listed names declare no conflict of interest to disclose., (Copyright © 2019 Elsevier B.V. All rights reserved.)

Published
2020
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4. Transition metal oxide nanoparticles are effective in inhibiting lung cancer cell survival in the hypoxic tumor microenvironment.

Author

Pandey N, Dhiman S, Srivastava T, and Majumder S

Subjects
A549 Cells, Antineoplastic Agents chemistry, Antineoplastic Agents pharmacology, Blotting, Western, Cell Survival drug effects, Flow Cytometry, Histones metabolism, Humans, Lung Neoplasms metabolism, Lung Neoplasms pathology, Microscopy, Electron, Scanning, Poly (ADP-Ribose) Polymerase-1 metabolism, Reactive Oxygen Species metabolism, Spectroscopy, Fourier Transform Infrared, Surface Plasmon Resonance, Thermogravimetry, Transition Elements chemistry, X-Ray Diffraction, Apoptosis drug effects, Metal Nanoparticles, Oxides pharmacology, Transition Elements pharmacology, Tumor Microenvironment
Abstract

Background: The transition metal oxide nanoparticles are in focus for their anti-cancer potential. In this study we have synthesized and characterized CuO, NiO and Fe2O3 nanoparticles and, investigated their cytotoxic potential in the heterogeneous tumour microenvironment., Methods: Nanoparticles were synthesized by aqueous precipitation method and characterized with UV-Visible spectrophotometer, Fourier transform infrared spectroscopy (FTIR), Scanning electron microscopy (SEM) and X-ray diffraction (XRD). Cell viability of lung cancer cells (A549) grown in normoxia (18%O2) and hypoxia (1%O2) was determined for all nanoparticles. The mechanism of cell death was assessed by nuclear morphological analysis, flow cytometry analysis and western blotting. Generation of intracellular ROS in treated cells and its contribution to cell viability was determined., Results: The synthesized metal oxide nanoparticles were successfully characterized with SEM, spectroscopy and X-ray diffraction patterns. Cell viability of lung cancer cells was compromised in both normoxia and hypoxia. ROS generation was shown to contribute to cellular toxicity in CuO, but not NiO and Fe2O3., Conclusion: We have shown the therapeutic potential of CuO, NiO and Fe2O3 nanoparticles in non small cell lung cancer cells cultured in hypoxia, a relevant feature of solid tumors along with normoxia. The newly synthesized nanoparticles showed efficacy in both conditions., General Significance: Hypoxia drives metabolic alterations and epigenetic modifications in the tumor microenvironment. By using conditions that mimic tumour microenvironment, this study expands the possibility of using metal oxide nanoparticles as a therapeutic agent for lung cancer treatment., (Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.)

Published
2016
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