1. [28] Design and characterization of gramicidin channels
- Author
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Olaf S. Andersen, S Shobana, Denise V. Greathouse, Lyndon L. Providence, and Roger E. Koeppe
- Subjects
chemistry.chemical_compound ,chemistry ,Biochemistry ,polycyclic compounds ,technology, industry, and agriculture ,Gramicidin ,Biophysics ,lipids (amino acids, peptides, and proteins) ,Biological membrane ,Model system ,Ion channel ,Characterization (materials science) - Abstract
This article summarizes methods for the chemical synthesis and biophysical characterization of gramicidins with varying sequences and labels. The family of gramicidin channels has developed into a powerful model system for understanding fundamental properties, interactions, and dynamics of proteins and lipids generally, and ion channels specifically, in biological membranes.
- Published
- 1999
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