1. Challenges for diagnosis and control of cystic hydatid disease
- Author
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Tamsin S. Barnes, Peter Deplazes, David Jenkins, Alexander Mathis, Paul R. Torgerson, Mar Siles-Lucas, Bruno Gottstein, Iskender Ziadinov, David D. Heath, University of Zurich, and Barnes, T S
- Subjects
10078 Institute of Parasitology ,medicine.medical_specialty ,1109 Insect Science ,Veterinary (miscellaneous) ,Population ,2405 Parasitology ,Developing country ,610 Medicine & health ,Disease ,Praziquantel ,Dogs ,Echinococcosis ,600 Technology ,Zoonoses ,Epidemiology ,parasitic diseases ,Control ,Sylvatic hosts ,medicine ,Animals ,Humans ,Diagnosis in humans ,10599 Chair in Veterinary Epidemiology ,Challenges ,Echinococcus granulosus ,Intensive care medicine ,education ,Anthelmintics ,education.field_of_study ,630 Agriculture ,biology ,Clinical Laboratory Techniques ,2725 Infectious Diseases ,biology.organism_classification ,medicine.disease ,Hydatid disease ,3401 Veterinary (miscellaneous) ,Vaccination ,Infectious Diseases ,Diagnosis in animals ,Insect Science ,Immunology ,570 Life sciences ,Sylvatic cycle ,Parasitology - Abstract
7 páginas. -- The definitive version is available at http://www.journals.elsevier.com/acta-tropica/#description, This paper is based on the experience of the authors, with the aim to define the challenges for Echinococcus granulosus (E.g./CE) diagnosis and control for those countries that may now or in the future be contemplating control of hydatid disease. A variety of methods are available for diagnosis in humans but a universal gold standard is lacking. Diagnosis in definitive hosts can avoid necropsy by the use of methods such as coproantigen detection but test performance is variable between populations. A sylvatic cycle adds challenges in some countries and the epidemiology of the parasite in these hosts is poorly understood. Control by solely administering praziquantel to dogs is not effective in developing countries where the disease is endemic. Additional avenues to pursue include the instigation of participatory planning, use of an existing vaccination for intermediate hosts and development of a vaccine and long-acting anthelmitic implants for definitive hosts. Promoting public acceptance of control of the dog population by humane euthanasia and reduced reproduction is also essential.
- Published
- 2012