1. Facile synthesis and rheological characterization of nanocomposite hyaluronan-organoclay hydrogels.
- Author
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Mourycová J, Datta KKR, Procházková A, Plotěná M, Enev V, Smilek J, Másílko J, and Pekař M
- Subjects
- Aluminum Silicates chemical synthesis, Biocompatible Materials chemical synthesis, Clay, Hyaluronic Acid chemical synthesis, Hydrogels chemical synthesis, Nanocomposites chemistry, Rheology, Water chemistry, Aluminum Silicates chemistry, Biocompatible Materials chemistry, Hyaluronic Acid chemistry, Hydrogels chemistry
- Abstract
We report a facile methodology for the synthesis of inorganic-organic hydrogels based on integrative assembly of aminopropyl magnesium phyllosilicate (aminoclay) and sodium salt of hyaluronic acid. The viscoelastic materials produced by electrostatic interactions and crosslinking of hyaluronan in the presence of exfoliated synthetic organoclay results in the formation of gel-like behavior retaining a high amount of water. This was confirmed by a rheological study revealing significant dominance of the elastic response over the entire deformation frequency range used. The mechanical strength of the aminoclay-hyaluronan hydrogels was found to be higher than that for related materials based on poly(vinylpyrrolidone)-aminoclay hydrogels., (Copyright © 2018 Elsevier B.V. All rights reserved.)
- Published
- 2018
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