1. Sex differences in food choices, adherence to dietary recommendations and plasma lipid profile in type 2 diabetes - The TOSCA.IT study
- Author
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Christian Caselli, M. C. Ruffo, Fabrizio Cappellini, Maria Masulli, P. Di Bartolo, Carmela Giordano, Giovanni Sartore, G. Citro, L. Corsi, Stefano Signorini, Giorgio Clemente, G. Mancastroppa, M. Mori, Elena Ceccarelli, Raffaella Buzzetti, Roberto Anichini, Olga Vaccaro, Gabriele Perriello, A. C. Babini, Vittorio Krogh, L. Tonutti, Sergio Giuseppe Longhitano, Laura Salvi, Carlo Giorda, Agostino Consoli, R. Carpinteri, M. E. Rinaldi, Chiara Mazzucchelli, A. Zogheri, Massimo Boemi, A. De Gregorio, Clarissa Zamboni, Monia Garofolo, S. Cocozza, Enzo Bonora, Veronica Montani, C. Scaranna, Giovanna Riccardi, Lucia Fontana, G. Di Cianni, Mauro Cignarelli, C. Iovine, Sara Grioni, Martina Vitale, Vitale, Marilena, Masulli, Maria, Cocozza, Sara, Anichini, R., Babini, A. C., Boemi, M., Bonora, E., Buzzetti, R., Carpinteri, R., Caselli, C., Ceccarelli, E., Cignarelli, M., Citro, G., Clemente, G., Consoli, A., Corsi, L., De Gregorio, A., Di Bartolo, P., Di Cianni, G., Fontana, L., Garofolo, M., Giorda, C. B., Giordano, C., Grioni, S., Iovine, Ciro, Longhitano, S., Mancastroppa, G., Mazzucchelli, C., Montani, V., Mori, M., Perriello, G., Rinaldi, M. E., Ruffo, M. C., Salvi, L., Sartore, G., Scaranna, C., Tonutti, L., Zamboni, C., Zogheri, A., Krogh, V., Cappellini, F., Signorini, S., Riccardi, Gabriele, and Vaccaro, Olga
- Subjects
Male ,Time Factors ,Healthy Diet ,Endocrinology, Diabetes and Metabolism ,Saturated fat ,Medicine (miscellaneous) ,Type 2 diabetes ,Cardiovascular risk factors ,Diabetes ,Dietary habits ,Men ,Nutritional recommendations ,Sex differences ,Women ,Nutrition and Dietetics ,Cardiology and Cardiovascular Medicine ,Diabete ,Recommended Dietary Allowances ,Choice Behavior ,chemistry.chemical_compound ,0302 clinical medicine ,Endocrinology ,Risk Factors ,Aged ,Biomarkers ,Diabetes Mellitus, Type 2 ,Female ,Food Preferences ,Humans ,Italy ,Lipids ,Middle Aged ,Nutrition Assessment ,Sex Factors ,Surveys and Questionnaires ,Treatment Outcome ,Feeding Behavior ,Patient Compliance ,Food choice ,Medicine ,030212 general & internal medicine ,Food science ,Diabetes and Metabolism ,Saturated fatty acid ,Diet, Healthy ,Type 2 ,030209 endocrinology & metabolism ,Added sugar ,Dietary habit ,03 medical and health sciences ,Diabetes mellitus ,Diabetes Mellitus ,Healthy ,business.industry ,Unsaturated fat ,Nutritional recommendation ,Sex difference ,medicine.disease ,Diet ,chemistry ,Glycated hemoglobin ,business - Abstract
Background and aims: Diabetic women have a more adverse plasma lipid profile than men. Sex differences in dietary habits may play a role, but are little investigated. The study evaluates the quality of diet, adherence to the nutritional recommendations of the Diabetes and Nutrition Study Group and their relation with plasma lipid in men and women with diabetes. Methods and results: We studied 2573 people, aged 50e75, enrolled in the TOSCA.IT study (clinicaltrials.gov; NCT00700856). Plasma lipids were measured centrally. Diet was assessed with a semi-quantitative food frequency questionnaire.Women had a more adverse plasma lipid profile than men.Women consumed significantly more legumes, vegetables, fruits, eggs, milk, vegetable oils, and added sugar, whereas men consumed more starchy foods, soft drinks and alcoholic beverages. This stands for a higher proportion (%) of energy intake from saturated fat and added sugar (12.0 2.4 vs 11.5 2.5 and 3.4 3.2 vs 2.3 3.2, P < 0.04), and a higher intake of fiber (11.2 2.8 vs 10.4 2.6 g/1000 Kcal/day) in women. Adherence to the recommendations for saturated fat and fiber consumption was associated with significantly lower LDL-cholesterol regardless of sex. Adherence to the recommendations for added sugars was associated with significantly lower triglycerides and higher HDL-cholesterol in men and women. Conclusions: Men and women with diabetes show significant differences in adherence to nutritional recommendations, but sex differences in plasma lipid profile are unlikely to be explained by nutritional factors. Adherence to the nutritional recommendations is associated with a better plasma lipid profile regardless of sex, thus reinforcing the importance of substituting saturated for unsaturated fat sources, increasing fiber and reducing added sugar intake.
- Published
- 2016
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