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Your search keyword '"Chia Ding Liao"' showing total 2 results
Start Over Author "Chia Ding Liao" Publisher elsevier
2 results on '"Chia Ding Liao"'

1. Lignan glycosides from sesame meal exhibit higher oral bioavailability and antioxidant activity in rat after nano/submicrosizing

Author

Wei-Lun Hung, Chia-Ding Liao, Wen-Chien Lu, Chi-Tang Ho, and Lucy Sun Hwang

Subjects
Sesaminol triglucoside, Sesaminol, Nanotechnology, Enterodiol, Enterolactone, Tissue distribution, Nutrition. Foods and food supply, TX341-641
Abstract

Lignan glycosides are one of the major bioactive components in sesame meal. In the current study, we evaluated whether the absorption efficiency of lignan glycosides from sesame meal (LGSM) increases after wet milling. The current data show that oral bioavailability of LGSM significantly elevated from 0.18 to 0.26% after nano/submicro-sizing due to the smaller particle size and larger surface area. Oral administration of nano/submicro-sized LGSM (N-LGSM) significantly increased the concentrations of sesaminol triglucoside and sesaminol glucuronide in rat urine compared to administration of LGSM that was not nano/submicro-sized. More importantly, oral administration of N-LGSM increased the concentrations of enterolactone and enterodiol found in the plasma, liver, kidney, small intestine and urine of rats, suggesting that the nano/submicro-sizing process greatly improved the accessibility of intestinal microbiota to LGSM. In addition, oral administration of N-LGSM remarkably alleviated lipid peroxidation and increased antioxidant enzyme activities against tert-butyl hydroperoxide-induced oxidative damage in rats.

Published
2016
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2. Multi-residue analysis using liquid chromatography tandem mass spectrometry for detection of 20 coccidiostats in poultry, livestock, and aquatic tissues

Author

Yu-Hsun Lai, Der-Yuan Wang, Guan-Jhih Peng, Chia-Ding Liao, Shun-Hsien Chang, Ya-Min Kao, Su-Hsiang Tseng, and Chih-Neng Huang

Subjects
Swine, 030309 nutrition & dietetics, Formic acid, Eggs, lcsh:TX341-641, Kidney, Tandem mass spectrometry, Quechers, 01 natural sciences, 03 medical and health sciences, chemistry.chemical_compound, Tandem Mass Spectrometry, Liquid chromatography–mass spectrometry, Coccidiostats, Ammonium formate, Animals, Pharmacology, Detection limit, 0303 health sciences, Chromatography, Muscles, 010401 analytical chemistry, Extraction (chemistry), lcsh:RM1-950, Fishes, 0104 chemical sciences, Milk, lcsh:Therapeutics. Pharmacology, Liver, chemistry, Cattle, Chickens, lcsh:Nutrition. Foods and food supply, Chromatography, Liquid, Food Science
Abstract

In this study, we developed a novel analysis method based on liquid chromatography/tandem mass spectrometry (LC–MS/MS) to allow the simultaneous identification of 20 coccidiostats in eight matrix categories, including the muscles of chicken, swine, cow, and fish as well as chicken eggs, bovine milk, and porcine viscera. In the pretreatment procedure, acetonitrile/methanol (95:5, v/v) containing 1% formic acid, 5 g of sodium acetate, and 6.0 g of anhydrous magnesium sulfate was used for extraction, followed by a clean-up procedure using n-hexane saturated with ACN to facilitate the elimination of analytes from high lipid samples. Chromatographic separations were achieved using a Poroshell 120SB C18 column and operated with a gradient mobile phase system consisting of methanol (with 0.1% formic acid) and 5 mM ammonium formate, and the MS detection was monitored simultaneously. The method was validated in accordance with the Guidelines for the Validation of Food Chemical Methods by the Taiwan Food and Drug Administration. The limit of quantitation among 8 matrices were 0.5–2 ng g−1. The proposed method proved highly effective in detecting the presence of targeted veterinary drugs, providing a high degree of precision and accuracy over a broad range of matrices. Keywords: Coccidiostats, LC–MS/MS, Multi-residue analysis, QuEChERS, Veterinary drugs

Published
2019

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