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Your search keyword '"C. Casasnovas Pons"' showing total 2 results
Start Over Author "C. Casasnovas Pons" Publisher elsevier
2 results on '"C. Casasnovas Pons"'

1. 21166. AFECTACIÓN NEUROLÓGICA EN PACIENTES CON TÍTULOS ALTOS DE ANTICUERPOS GAD EN SUERO

Author

P. Lombardo del Toro, M. Falip Centellas, S. Jaraba Armas, G. Hernández Pérez, V. Nedkova Hristova, C. Casasnovas Pons, S. Jaumá Classen, L. González Mera, R. Gómez Llopico, L. García Serrano, P. Valín Villanueva, J. Sala i Padro, M. Angerri Nadal, M. Bea Sintes, J. Villarreal Miñano, and F. Morandeira Rego

Subjects
Neurology. Diseases of the nervous system, RC346-429
Published
2024
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2. MuSK autoantibodies in myasthenia gravis detected by cell based assay - A multinational study

Author

John Tzartos, Anastasios Tsonis, Kleopas A. Kleopa, Chantal M. E. Tallaksen, Dragana Lavrnic, Ivana Basta, Anthony Behin, Socrates J. Tzartos, Feza Deymeer, Stojan Peric, Mario Losen, C. Casasnovas Pons, Angelina H. Maniaol, Carlo Antozzi, Sonia Berrih-Aknin, Amelia Evoli, M. De Baets, F. Hanisch, E. Matsigkou, Renato Mantegazza, Tassos C. Kyriakides, Francesca Andreetta, Anna Kostera-Pruszczyk, Piotr Szczudlik, Güher Saruhan-Direskeneli, Konstantinos Lazaridis, Tarek Sharshar, Paraskevi Zisimopoulou, M. Jakubíkova, A. Vaknin, Hacer Durmus, Vasiliki Zouvelou, Eleni Zamba-Papanicolaou, Talma Brenner, Pilar Martinez-Martinez, Beata Szyluk, Jiri Pitha, Psychiatrie & Neuropsychologie, and RS: MHeNs - R3 - Neuroscience

Subjects
Adult, Male, International Cooperation, Immunology, Radioimmunoassay, Thymus Gland, Diagnosis, medicine, Immunology and Allergy, Humans, Receptors, Cholinergic, Cell based assay, Myasthenia gravis, LDL-Receptor Related Proteins, Acetylcholine receptor, Aged, MuSK, Autoantibodies, Neuromyelitis optica, biology, business.industry, Multiple sclerosis, Neuromyelitis Optica, Autoantibody, Receptor Protein-Tyrosine Kinases, Hyperplasia, Middle Aged, medicine.disease, Flow Cytometry, 3. Good health, Settore MED/26 - NEUROLOGIA, Neurology, biology.protein, Cell-based assay, Female, Neurology (clinical), Thymus Hyperplasia, Antibody, business
Abstract

Seronegativemyastheniagravis(MG) presents a serious gap in MG diagnosis and understanding. We applied acellbasedassay(CBA) for the detection of muscle specific kinase (MuSK) antibodies undetectable by radioimmunoassay. We tested 633 triple-seronegative MG patients' sera from 13 countries, detecting 13% as positive.MuSKantibodies were found, at significantly lower frequencies, in 1.9% of healthy controls and 5.1% of other neuroimmune disease patients, including multiple sclerosis and neuromyelitis optica. The clinical data of the newly diagnosedMuSK-MG patients are presented. 27% of ocular seronegative patients wereMuSKantibody positive. Moreover, 23% had thymic hyperplasia suggesting that thymic abnormalities are more common than believed.

Published
2015
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