733 results on '"Brown, M."'
Search Results
2. Contributors
- Author
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Alfonso, Amparo, primary, Álvarez-Rivera, Gerardo, additional, Barceló, Damia, additional, Berardinelli, Diletta, additional, Berretta, Paolo, additional, Bobály, Balázs, additional, Botana, Ana M., additional, Botana, Luis M., additional, Bottillo, Grazia, additional, Briganti, Stefania, additional, Brunelli, C., additional, Calderón, Carlos, additional, Camera, Emanuela, additional, Čelić, Mira, additional, Chankvetadze, Bezhan, additional, Cifuentes, Alejandro, additional, D’Amato, Maura, additional, Dal Bosco, Chiara, additional, de Alda, Miren Lopez, additional, Di Trana, Annagiulia, additional, Domínguez-Hernández, Cristopher, additional, Donato, Paola, additional, Dugo, Paola, additional, Eylem, Cemil Can, additional, Fan, Yuchen, additional, Farré, Marinella, additional, Garrido Frenich, Antonia, additional, Gentili, Alessandra, additional, Gieroba, Barbara, additional, Gika, Helen, additional, González-Jartín, Jesús M., additional, González-Sálamo, Javier, additional, Goyon, Alexandre, additional, Hamase, Kenji, additional, Hanna-Brown, M., additional, Hartonen, Kari, additional, Hernández-Borges, Javier, additional, Herrero, Miguel, additional, Hradski, J., additional, Iadarola, Paolo, additional, Ibáñez, Elena, additional, Ishii, Chiharu, additional, Jiménez-Skrzypek, Gabriel, additional, Jóźwiak, Krzysztof, additional, Kataoka, Hiroyuki, additional, Koçak, Engin, additional, Koga, Reiko, additional, Kozak, Radoslaw P., additional, Lämmerhofer, Michael, additional, Lestremau, F., additional, Li, Shaoping, additional, López-Ruiz, Rosalía, additional, Maiellaro, Miriam, additional, Mandrioli, Roberto, additional, Marazuela, M.D., additional, Marín-Sáez, Jesús, additional, Matys, Joanna, additional, Mercolini, Laura, additional, Michalke, Bernhard, additional, Mondello, Luigi, additional, Montanari, Eva, additional, Nemutlu, Emirhan, additional, Nischwitz, Volker, additional, Ottaviani, Monica, additional, Parshintsev, Jevgeni, additional, Peluso, Paola, additional, Perez, Sandra, additional, Petrovic, Mira, additional, Plumb, Robert S, additional, Poole, Colin F., additional, Protti, Michele, additional, Qin, You, additional, Riekkola, Marja-Liisa, additional, Romero-González, Roberto, additional, Royle, Louise, additional, Sánchez-Martínez, José David, additional, Sciuto, Lorenzo, additional, Socas-Rodríguez, Bárbara, additional, Szucs, R., additional, Theodoridis, Georgios, additional, Tini, Anastasio, additional, Todoroki, Kenichiro, additional, Valdés, Alberto, additional, Vieytes, Mercedes R., additional, Viglio, Simona, additional, Wilson, Ian D, additional, Zhang, Kelly, additional, and Zhao, Jing, additional
- Published
- 2023
- Full Text
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3. A New Method to Determine the Transmembrane Conformation of Substrates in Intramembrane Proteolysis by Deep-UV Resonance Raman Spectroscopy
- Author
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Cooley, J.W., primary, Abdine, A., additional, Brown, M., additional, Chavez, J., additional, Lada, B., additional, JiJi, R.D., additional, and Ubarretxena-Belandia, I., additional
- Published
- 2017
- Full Text
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4. Flavor Enhancers: Characteristics and Uses
- Author
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Baines, D., primary and Brown, M., additional
- Published
- 2016
- Full Text
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5. Investigation of deuterium trapping and release in the JET divertor during the third ILW campaign using TDS
- Author
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JET Contributors, Likonen, J., Heinola, K., De Backer, A., Baron-Wiechec, A., Catarino, N., Jepu, I., Ayres, C. F., Coad, P., Matthews, G. F., Widdowson, A., Abduallev, S., Abhangi, M., Abreu, P., Afzal, M., Aggarwal, K. M., Ahlgren, T., Ahn, J. H., Aho-Mantila, L., Aiba, N., Airila, M., Albanese, R., Aldred, V., Alegre, D., Alessi, E., Aleynikov, P., Alfier, A., Alkseev, A., Allinson, M., Alper, B., Alves, E., Ambrosino, G., Ambrosino, R., Amicucci, L., Amosov, V., Sunden, E. Andersson, Angelone, M., Anghel, M., Angioni, C., Appel, L., Appelbee, C., Arena, P., Ariola, M., Arnichand, H., Arshad, S., Ash, A., Ashikawa, N., Aslanyan, V., Asunta, O., Auriemma, F., Austin, Y., Avotina, L., Axton, M. D., Ayres, C., Bacharis, M., Baciero, A., Baiao, D., Bailey, S., Baker, A., Balboa, I., Balden, M., Balshaw, N., Bament, R., Banks, J. W., Baranov, Y. F., Barnard, M. A., Barnes, D., Barnes, M., Barnsley, R., Wiechec, A. Baron, Orte, L. Barrera, Baruzzo, M., Basiuk, V., Bassan, M., Bastow, R., Batista, A., Batistoni, P., Baughan, R., Bauvir, B., Baylor, L., Bazylev, B., Beal, J., Beaumont, P. S., Beckers, M., Beckett, B., Becoulet, A., Bekris, N., Beldishevski, M., Bell, K., Belli, F., Bellinger, M., Belonohy, E., Ben Ayed, N., Benterman, N. A., Bergsaker, H., Bernardo, J., Bernert, M., Berry, M., Bertalot, L., Besliu, C., Beurskens, M., Bieg, B., Bielecki, J., Biewer, T., Bigi, M., Bilkova, P., Binda, F., Bisoffi, A., Bizarro, J. P. S., Bjorkas, C., Blackburn, J., Blackman, K., Blackman, T. R., Blanchard, P., Blatchford, P., Bobkov, V., Boboc, A., Bodnar, G., Bogar, O., Bolshakova, I., Bolzonella, T., Bonanomi, N., Bonelli, F., Boom, J., Booth, J., Borba, D., Borodin, D., Borodkina, I., Botrugno, A., Bottereau, C., Boulting, P., Bourdelle, C., Bowden, M., Bower, C., Bowman, C., Boyce, T., Boyd, C., Boyer, H. J., Bradshaw, J. M. A., Braic, V., Bravanec, R., Breizman, B., Bremond, S., Brennan, P. D., Breton, S., Brett, A., Brezinsek, S., Bright, M. D. J., Brix, M., Broeckx, W., Brombin, M., Broslawski, A., Brown, D. P. D., Brown, M., Bruno, E., Bucalossi, J., Buch, J., Buchanan, J., Buckley, M. A., Budny, R., Bufferand, H., Bulman, M., Bulmer, N., Bunting, P., Buratti, P., Burckhart, A., Buscarino, A., Busse, A., Butler, N. K., Bykov, I., Byrne, J., Cahyna, P., Calabro, G., Calvo, I., Camenen, Y., Camp, P., Campling, D. C., Cane, J., Cannas, B., Capel, A. J., Card, P. J., Cardinali, A., Carman, P., Carr, M., Carralero, D., Carraro, L., Carvalho, B. B., Carvalho, I., Carvalho, P., Casson, F. J., Castaldo, C., Caumont, J., Causa, F., Cavazzana, R., Cave-Ayland, K., Cavinato, M., Cecconello, M., Ceccuzzi, S., Cecil, E., Cenedese, A., Cesario, R., Challis, C. D., Chandler, M., Chandra, D., Chang, C. S., Chankin, A., Chapman, I. T., Chapman, S. C., Chernyshova, M., Chitarin, G., Ciraolo, G., Ciric, D., Citrin, J., Clairet, F., Clark, E., Clark, M., Clarkson, R., Clatworthy, D., Clements, C., Cleverly, M., Coad, J. P., Coates, P. A., Cobalt, A., Coccorese, V., Cocilovo, V., Coda, S., Coelho, R., Coenen, J. W., Coffey, I., Colas, L., Collins, S., Conka, D., Conroy, S., Conway, N., Coombs, D., Cooper, D., Cooper, S. R., Corradino, C., Corre, Y., Corrigan, G., Cortes, S., Coster, D., Couchman, A. S., Cox, M. P., Craciunescu, T., Cramp, S., Craven, R., Crisanti, F., Croci, G., Croft, D., Crombe, K., Crowe, R., Cruz, N., Cseh, G., Cufar, A., Cullen, A., Curuia, M., Czarnecka, A., Dabirikhah, H., Dalgliesh, P., Dalley, S., Dankowski, J., Darrow, D., Davies, O., Davis, W., Day, C., Day, I. E., De Bock, M., Castro, A. de, Cal, E. de la, Luna, E. de la, De Masi, G., Pablos, J. L. de, Temmerman, G., De, De Tommasi, G., Vries, P. de, Deakin, K., Deane, J., Agostini, F. Degli, Dejarnac, R., Delabie, E., Harder, N. den, Dendy, R. O., Denis, J., Denner, P., Devaux, S., Devynck, P., Di Maio, F., Di Siena, A., Di Troia, C., Dinca, P., D’Inca, R., Ding, B., Dittmar, T., Doerk, H., Doerner, R. P., Donne, T., Dorling, S. E., Dormido-Canto, S., Doswon, S., Douai, D., Doyle, P. T., Drenik, A., Drewelow, P., Drews, P., Duckworth, Ph, Dumont, R., Dumortier, P., Dunai, D., Dunne, M., Duran, I., Durodie, F., Dutta, P., Duval, B. P., Dux, R., Dylst, K., Dzysiuk, N., Edappala, P. V., Edmond, J., Edwards, A. M., Edwards, J., Eich, Th, Ekedahl, A., El-Jorf, R., Elsmore, C. G., Enachescu, M., Ericsson, G., Eriksson, F., Eriksson, J., Eriksson, L. G., Esposito, B., Esquembri, S., Esser, H. G., Esteve, D., Evans, B., Evans, G. E., Evison, G., Ewart, G. D., Fagan, D., Faitsch, M., Falie, D., Fanni, A., Fasoli, A., Faustin, J. M., Fawlk, N., Fazendeiro, L., Fedorczak, N., Felton, R. C., Fenton, K., Fernades, A., Fernandes, H., Ferreira, J., Fessey, J. A., Fevrier, O., Ficker, O., Field, A., Fietz, S., Figueiredo, A., Figueiredo, J., Fil, A., Finburg, P., Firdaouss, M., Fischer, U., Fittill, L., Fitzgerald, M., Flammini, D., Flanagan, J., Fleming, C., Flinders, K., Fonnesu, N., Fontdecaba, J. M., Formisano, A., Forsythe, L., Fortuna, L., Fortuna-Zalesna, E., Fortune, M., Foster, S., Franke, T., Franklin, T., Frasca, M., Frassinetti, L., Freisinger, M., Fresa, R., Frigione, D., Fuchs, V., Fuller, D., Futatani, S., Fyvie, J., Gal, K., Galassi, D., Galazka, K., Galdon-Quiroga, J., Gallagher, J., Gallart, D., Galvao, R., Gao, X., Gao, Y., Garcia, J., Garcia-Carrasco, A., Garcia-Munoz, M., Gardarein, J.-L., Garzotti, L., Gaudio, P., Gauthier, E., Gear, D. F., Gee, S. J., Geiger, B., Gelfusa, M., Gerasimov, S., Gervasini, G., Gethins, M., Ghani, Z., Ghate, M., Gherendi, M., Giacalone, J. C., Giacomelli, L., Gibson, C. S., Giegerich, T., Gil, C., Gil, L., Gilligan, S., Gin, D., Giovannozzi, E., Girardo, J. B., Giroud, C., Giruzzi, G., Gloeggler, S., Godwin, J., Goff, J., Gohil, P., Goloborod’ko, V., Gomes, R., Goncalves, B., Goniche, M., Goodliffe, M., Goodyear, A., Gorini, G., Gosk, M., Goulding, R., Goussarov, A., Gowland, R., Graham, B., Graham, M. E., Graves, J. P., Grazier, N., Grazier, P., Green, N. R., Greuner, H., Grierson, B., Griph, F. S., Grisolia, C., Grist, D., Groth, M., Grove, R., Grundy, C. N., Grzonka, J., Guard, D., Guerard, C., Guillemaut, C., Guirlet, R., Gurl, C., Utoh, H. H., Hackett, L. J., Hacquin, S., Hagar, A., Hager, R., Hakola, A., Halitovs, M., Hall, S. J., Cook, S. P. Hallworth, Hamlyn-Harris, C., Hammond, K., Harrington, C., Harrison, J., Harting, D., Hasenbeck, F., Hatano, Y., Hatch, D. R., Haupt, T. D. V., Hawes, J., Hawkes, N. C., Hawkins, J., Hawkins, P., Haydon, P. W., Hayter, N., Hazel, S., Heesterman, P. J. L., Hellesen, C., Hellsten, T., Helou, W., Hemming, O. N., Hender, T. C., Henderson, M., Henderson, S. S., Henriques, R., Hepple, D., Hermon, G., Hertout, P., Hidalgo, C., Highcock, E. G., Hill, M., Hillairet, J., Hillesheim, J., Hillis, D., Hizanidis, K., Hjalmarsson, A., Hobirk, J., Hodille, E., Hogben, C. H. A., Hogeweij, G. M. D., Hollingsworth, A., Hollis, S., Homfray, D. A., Horacek, J., Hornung, G., Horton, A. R., Horton, L. D., Horvath, L., Hotchin, S. P., Hough, M. R., Howarth, P. J., Hubbard, A., Huber, A., Huber, V., Huddleston, T. M., Hughes, M., Huijsmans, G. T. A., Hunter, C. L., Huynh, P., Hynes, A. M., Iglesias, D., Imazawa, N., Imbeaux, F., Imrisek, M., Incelli, M., Innocente, P., Irishkin, M., Ivanova-Stanik, I., Jachmich, S., Jacobsen, A. S., Jacquet, P., Jansons, J., Jardin, A., Jarvinen, A., Jaulmes, F., Jednorog, S., Jenkins, I., Jeong, C., Joffrin, E., Johnson, R., Johnson, T., Johnston, Jane, Joita, L., Jones, G., Jones, T. T. C., Hoshino, K. K., Kallenbach, A., Kamiya, K., Kaniewski, J., Kantor, A., Kappatou, A., Karhunen, J., Karkinsky, D., Karnowska, I., Kaufman, M., Kaveney, G., Kazakov, Y., Kazantzidis, V., Keeling, D. L., Keenan, T., Keep, J., Kempenaars, M., Kennedy, C., Kenny, D., Kent, J., Kent, O. N., Khilkevich, E., Kim, H. T., Kim, H. S., Kinch, A., King, C., King, D., King, R. F., Kinna, D. J., Kiptily, V., Kirk, A., Kirov, K., Kirschner, A., Kizane, G., Klepper, C., Klix, A., Knight, P., Knipe, S. J., Knott, S., Kobuchi, T., Koechl, F., Kocsis, G., Kodeli, I., Kogan, L., Kogut, D., Koivuranta, S., Kominis, Y., Koeppen, M., Kos, B., Koskela, T., Koslowski, H. R., Koubiti, M., Kovari, M., Kowalska-Strzeciwilk, E., Krasilnikov, A., Krasilnikov, V., Krawczyk, N., Kresina, M., Krieger, K., Krivska, A., Kruezi, U., Ksiazek, I., Kukushkin, A., Kundu, A., Kurki-Suonio, T., Kwak, S., Kwiatkowski, R., Kwon, O. J., Laguardia, L., Lahtinen, A., Laing, A., Lam, N., Lambertz, H. T., Lane, C., Lang, P. T., Lanthaler, S., Lapins, J., Lasa, A., Last, J. R., Laszynska, E., Lawless, R., Lawson, A., Lawson, K. D., Lazaros, A., Lazzaro, E., Leddy, J., Lee, S., Lefebvre, X., Leggate, H. J., Lehmann, J., Lehnen, M., Leichtle, D., Leichuer, P., Leipold, F., Lengar, I., Lennholm, M., Lerche, E., Lescinskis, A., Lesnoj, S., Letellier, E., Leyland, M., Leysen, W., Li, L., Liang, Y., Linke, J., Linsmeier, Ch, Lipschultz, B., Liu, G., Liu, Y., Lo Schiavo, V. P., Loarer, T., Loarte, A., Lobel, R. C., Lomanowski, B., Lomas, P. J., Lonnroth, J., Lopez, J. M., Lopez-Razola, J., Lorenzini, R., Losada, U., Lovell, J. J., Loving, A. B., Lowry, C., Luce, T., Lucock, R. M. A., Lukin, A., Luna, C., Lungaroni, M., Lungu, C. P., Lungu, M., Lunniss, A., Lupelli, I., Lyssoivan, A., Macdonald, N., Macheta, P., Maczewa, K., Magesh, B., Maget, P., Maggi, C., Maier, H., Mailloux, J., Makkonen, T., Makwana, R., Malaquias, A., Malizia, A., Manas, P., Manning, A., Manso, M. E., Mantica, P., Mantsinen, M., Manzanares, A., Maquet, Ph, Marandet, Y., Marcenko, N., Marchetto, C., Marchuk, O., Marinelli, M., Marinucci, M., Markovic, T., Marocco, D., Marot, L., Marren, C. A., Marshal, R., Martin, A., Martin, Y., Martin de Aguilera, A., Martinez, F. J., Martin-Solis, J. R., Martynova, Y., Maruyama, S., Masiello, A., Maslov, M., Matejcik, S., Mattei, M., Maviglia, F., Mayer, M., Mayoral, M. L., May-Smith, T., Mazon, D., Mazzotta, C., McAdams, R., McCarthy, P. J., McClements, K. G., McCormack, O., McCullen, P. A., McDonald, D., McIntosh, S., McKean, R., McKehon, J., Meadows, R. C., Meakins, A., Medina, F., Medland, M., Medley, S., Meigh, S., Meigs, A. G., Meisl, G., Meitner, S., Meneses, L., Menmuir, S., Mergia, K., Merrigan, I. R., Mertens, Ph, Meshchaninov, S., Messiaen, A., Meyer, H., Mianowski, S., Michling, R., Middleton-Gear, D., Miettunen, J., Militello, F., Militello-Asp, E., Miloshevsky, G., Mink, F., Minucci, S., Miyoshi, Y., Mlynar, J., Molina, D., Monakhov, I., Moneti, M., Mooney, R., Moradi, S., Mordijck, S., Moreira, L., Moreno, R., Moro, F., Morris, A. W., Morris, J., Moser, L., Mosher, S., Moulton, D., Murari, A., Muraro, A., Murphy, S., Asakura, N. N., Na, Y. S., Nabais, F., Naish, R., Nakano, T., Nardon, E., Naulin, V., Nave, M. F. F., Nedzelski, I., Nemtsev, G., Nespoli, F., Neto, A., Neu, R., Neverov, V. S., Newman, M., Nicholls, K. J., Nicolas, T., Nielsen, A. H., Nielsen, P., Nilsson, E., Nishijima, D., Noble, C., Nocente, M., Nodwell, D., Nordlund, K., Nordman, H., Nouailletas, R., Nunes, I., Oberkofler, M., Odupitan, T., Ogawa, M. T., O’Gorman, T., Okabayashi, M., Olney, R., Omolayo, O., O’Mullane, M., Ongena, J., Orsitto, F., Orszagh, J., Oswuigwe, B. I., Otin, R., Owen, A., Paccagnella, R., Pace, N., Pacella, D., Packer, L. W., Page, A., Pajuste, E., Palazzo, S., Pamela, S., Panja, S., Papp, P., Paprok, R., Parail, V., Park, M., Diaz, F. Parra, Parsons, M., Pasqualotto, R., Patel, A., Pathak, S., Paton, D., Patten, H., Pau, A., Pawelec, E., Soldan, C. Paz, Peackoc, A., Pearson, I. J., Pehkonen, S.-P., Peluso, E., Penot, C., Pereira, A., Pereira, R., Puglia, P. P. Pereira, Thun, C. Perez von, Peruzzo, S., Peschanyi, S., Peterka, M., Petersson, P., Petravich, G., Petre, A., Petrella, N., Petrzilka, V., Peysson, Y., Pfefferle, D., Philipps, V., Pillon, M., Pintsuk, G., Piovesan, P., Pires dos Reis, A., Piron, L., Pironti, A., Pisano, F., Pitts, R., Pizzo, F., Plyusnin, V., Pomaro, N., Pompilian, O. G., Pool, P. J., Popovichev, S., Porfiri, M. T., Porosnicu, C., Porton, M., Possnert, G., Potzel, S., Powell, T., Pozzi, J., Prajapati, V., Prakash, R., Prestopino, G., Price, D., Price, M., Price, R., Prior, P., Proudfoot, R., Pucella, G., Puglia, P., Puiatti, M. E., Pulley, D., Purahoo, K., Puetterich, Th, Rachlew, E., Rack, M., Ragona, R., Rainford, M. S. J., Rakha, A., Ramogida, G., Ranjan, S., Rapson, C. J., Rasmussen, J. J., Rathod, K., Ratta, G., Ratynskaia, S., Ravera, G., Rayner, C., Rebai, M., Reece, D., Reed, A., Refy, D., Regan, B., Regana, J., Reich, M., Reid, N., Reimold, F., Reinhart, M., Reinke, M., Reiser, D., Rendell, D., Reux, C., Reyes Cortes, S. D. A., Reynolds, S., Riccardo, V., Richardson, N., Riddle, K., Rigamonti, D., Rimini, F. G., Risner, J., Riva, M., Roach, C., Robins, R. J., Robinson, S. A., Robinson, T., Robson, D. W., Roccella, R., Rodionov, R., Rodrigues, P., Rodriguez, J., Rohde, V., Romanelli, F., Romanelli, M., Romanelli, S., Romazanov, J., Rowe, S., Rubel, M., Rubinacci, G., Rubino, G., Ruchko, L., Ruiz, M., Ruset, C., Rzadkiewicz, J., Saarelma, S., Sabot, R., Safi, E., Sagar, P., Saibene, G., Saint-Laurent, F., Salewski, M., Salmi, A., Salmon, R., Salzedas, F., Samaddar, D., Samm, U., Sandiford, D., Santa, P., Santala, M. I. K., Santos, B., Santucci, A., Sartori, F., Sartori, R., Sauter, O., Scannell, R., Schlummer, T., Schmid, K., Schmidt, V., Schmuck, S., Schneider, M., Schoepf, K., Schworer, D., Scott, S. D., Sergienko, G., Sertoli, M., Shabbir, A., Sharapov, S. E., Shaw, A., Shaw, R., Sheikh, H., Shepherd, A., Shevelev, A., Shumack, A., Sias, G., Sibbald, M., Sieglin, B., Silburn, S., Silva, A., Silva, C., Simmons, P. A., Simpson, J., Simpson-Hutchinson, J., Sinha, A., Sipila, S. K., Sips, A. C. C., Siren, P., Sirinelli, A., Sjostrand, H., Skiba, M., Skilton, R., Slabkowska, K., Slade, B., Smith, N., Smith, P. G., Smith, R., Smith, T. J., Smithies, M., Snoj, L., Soare, S., Solano, E. R., Somers, A., Sommariva, C., Sonato, P., Sopplesa, A., Sousa, J., Sozzi, C., Spagnolo, S., Spelzini, T., Spineanu, F., Stables, G., Stamatelatos, I., Stamp, M. F., Staniec, P., Stankunas, G., Stan-Sion, C., Stead, M. J., Stefanikova, E., Stepanov, I., Stephen, A. V., Stephen, M., Stevens, A., Stevens, B. D., Strachan, J., Strand, P., Strauss, H. R., Strom, P., Stubbs, G., Studholme, W., Subba, F., Summers, H. P., Svensson, J., Swiderski, L., Szabolics, T., Szawlowski, M., Szepesi, G., Suzuki, T. T., Tal, B., Tala, T., Talbot, A. R., Talebzadeh, S., Taliercio, C., Tamain, P., Tame, C., Tang, W., Tardocchi, M., Taroni, L., Taylor, D., Taylor, K. A., Tegnered, D., Telesca, G., Teplova, N., Terranova, D., Testa, D., Tholerus, E., Thomas, J., Thomas, J. D., Thomas, P., Thompson, A., Thompson, C.-A., Thompson, V. K., Thorne, L., Thornton, A., Thrysoe, A. S., Tigwell, P. A., Tipton, N., Tiseanu, I., Tojo, H., Tokitani, M., Tolias, P., Tomes, M., Tonner, P., Towndrow, M., Trimble, P., Tripsky, M., Tsalas, M., Tsavalas, P., Jun, D. Tskhakaya, Turner, I., Turner, M. M., Turnyanskiy, M., Tvalashvili, G., Tyrrell, S. G. J., Uccello, A., Ul-Abidin, Z., Uljanovs, J., Ulyatt, D., Urano, H., Uytdenhouwen, I., Vadgama, A. P., Valcarcel, D., Valentinuzzi, M., Valisa, M., Olivares, P. Vallejos, Valovic, M., Van De Mortel, M., Van Eester, D., Van Renterghem, W., Rooij, G. J. van, Varje, J., Varoutis, S., Vartanian, S., Vasava, K., Vasilopoulou, T., Vega, J., Verdoolaege, G., Verhoeven, R., Verona, C., Rinati, G. Verona, Veshchev, E., Vianello, N., Vicente, J., Viezzer, E., Villari, S., Villone, F., Vincenzi, P., Vinyar, I., Viola, B., Vitins, A., Vizvary, Z., Vlad, M., Voitsekhovitch, I., Vondracek, P., Vora, N., Vu, T., Pires de Sa, W. W., Wakeling, B., Waldon, C. W. F., Walkden, N., Walker, M., Walker, R., Walsh, M., Wang, E., Wang, N., Warder, S., Warren, R. J., Waterhouse, J., Watkins, N. W., Watts, C., Wauters, T., Weckmann, A., Weiland, J., Weisen, H., Weiszflog, M., Wellstood, C., West, A. T., Wheatley, M. R., Whetham, S., Whitehead, A. M., Whitehead, B. D., Widdowson, A. M., Wiesen, S., Wilkinson, J., Williams, J., Williams, M., Wilson, A. R., Wilson, D. J., Wilson, H. R., Wilson, J., Wischmeier, M., Withenshaw, G., Withycombe, A., Witts, D. M., Wood, D., Wood, R., Woodley, C., Wray, S., Wright, J., Wright, J. C., Wu, J., Wukitch, S., Wynn, A., Xu, T., Yadikin, D., Yanling, W., Yao, L., Yavorskij, V., Yoo, M. G., Young, C., Young, D., Young, I. D., Young, R., Zacks, J., Zagorski, R., Zaitsev, F. S., Zanino, R., Zarins, A., Zastrow, K. D., Zerbini, M., Zhang, W., Zhou, Y., Zilli, E., Zoita, V., Zoletnik, S., Zychor, I., Universidad de Sevilla. Departamento de Física Atómica, Molecular y Nuclear, Universidad de Sevilla. RNM138: Física Nuclear Aplicada, Department of Physics, and Materials Physics
- Subjects
retention ,Nuclear and High Energy Physics ,Technology and Engineering ,Materials science ,Materials Science (miscellaneous) ,RETENTION ,TILES ,Thermal desorption ,Trapping ,Mass spectrometry ,114 Physical sciences ,01 natural sciences ,010305 fluids & plasmas ,Fusion, plasma och rymdfysik ,0103 physical sciences ,ddc:530 ,ta216 ,tiles ,ta218 ,010302 applied physics ,Jet (fluid) ,ta114 ,Physics ,Divertor ,Fusion, Plasma and Space Physics ,lcsh:TK9001-9401 ,Nuclear Energy and Engineering ,Deuterium ,13. Climate action ,lcsh:Nuclear engineering. Atomic power ,Atomic physics - Abstract
Selected set of samples from JET ITER-Like Wall (JET-ILW) divertor tiles exposed in 2015-2016 has been analysed using Thermal Desorption Spectrometry (TDS). The deuterium (D) amounts obtained with TDS were compared with Nuclear Reaction Analysis (NRA). The highest amount of D was found on the top part of inner divertor which has regions with the thickest deposited layers as for divertor tiles removed in 2014. This area resides deep in the scrape-off layer and plasma configurations for the second (ILW-2, 2013-2014) and the third (ILW-3, 2015-2016) JET-ILW campaigns were similar. Agreement between TDS and NRA is good on the apron of Tile 1 and on the upper vertical region whereas on the lower vertical region of Tile 1 the NRA results are clearly smaller than the TDS results. Inner divertor Tile 3 has somewhat less D than Tiles 0 and 1, and the D amount decreases towards the lower part of the tile. The D retention at the divertor inner and outer corner regions is not symmetric as there is more D retention poloidally at the inner than at the outer divertor corner. In most cases the TDS spectra for the ILW-3 samples are different from the corresponding ILW-2 spectra because HD and D-2 release occurs at higher temperatures than from the ILW-2 samples indicating that the low energy traps have been emptied during the plasma operations and that D is either in the energetically deep traps or located deeper in the sample. For complete list of authors see http://dx.doi.org/10.1016/j.nme.2019.03.012
- Published
- 2019
6. Tritium retention characteristics in dust particles in JET with ITER-like wall
- Author
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Otsuka, T., Masuzaki, S., Ashikawa, N., Hatano, Y., Asakura, Y., Suzuki, Tatsuya, Suzuki, Takumi, Isobe, K., Hayashi, T., Tokitani, M., Oya, Y., Hamaguchi, D., Kurotaki, H., Sakamoto, R., Tanigawa, Hiroyasu, Nakamichi, M., Widdowson, A., Rubel, M., Abduallev, S., Abhangi, M., Abreu, P., Afzal, M., Aggarwal, K. M., Ahlgren, T., Ahn, J. H., Aho-Mantila, L., Aiba, N., Airila, M., Albanese, R., Aldred, V., Alegre, D., Alessi, E., Aleynikov, P., Alfier, A., Alkseev, A., Allinson, M., Alper, B., Alves, E., Ambrosino, G., Ambrosino, R., Amicucci, L., Amosov, V., Sunden, E. Andersson, Angelone, M., Anghel, M., Angioni, C., Appel, L., Appelbee, C., Arena, P., Ariola, M., Arnichand, H., Arshad, S., Ash, A., Aslanyan, V., Asunta, O., Auriemma, F., Austin, Y., Avotina, L., Axton, M. D., Ayres, C., Bacharis, M., Baciero, A., Baiao, D., Bailey, S., Baker, A., Balboa, I., Balden, M., Balshaw, N., Bament, R., Banks, J. W., Baranov, Y. F., Barnard, M. 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T., Porosnicu, C., Porton, M., Possnert, G., Potzel, S., Powell, T., Pozzi, J., Prajapati, V., Prakash, R., Prestopino, G., Price, D., Price, M., Price, R., Prior, P., Proudfoot, R., Pucella, G., Puglia, P., Puiatti, M. E., Pulley, D., Purahoo, K., Puetterich, Th., Rachlew, E., Rack, M., Ragona, R., Rainford, M. S. J., Rakha, A., Ramogida, G., Ranjan, S., Rapson, C. J., Rasmussen, J. J., Rathod, K., Ratta, G., Ratynskaia, S., Ravera, G., Rayner, C., Rebai, M., Reece, D., Reed, A., Refy, D., Regan, B., Regana, J., Reich, M., Reid, N., Reimold, F., Reinhart, M., Reinke, M., Reiser, D., Rendell, D., Reux, C., Reyes Cortes, S. D. A., Reynolds, S., Riccardo, V., Richardson, N., Riddle, K., Rigamonti, D., Rimini, F. G., Risner, J., Riva, M., Roach, C., Robins, R. J., Robinson, S. A., Robinson, T., Robson, D. W., Roccella, R., Rodionov, R., Rodrigues, P., Rodriguez, J., Rohde, V., Romanelli, F., Romanelli, M., Romanelli, S., Romazanov, J., Rowe, S., Rubinacci, G., Rubino, G., Ruchko, L., Ruiz, M., Ruset, C., Rzadkiewicz, J., Saarelma, S., Sabot, R., Safi, E., Sagar, P., Saibene, G., Saint-Laurent, F., Salewski, M., Salmi, A., Salmon, R., Salzedas, F., Samaddar, D., Samm, U., Sandiford, D., Santa, P., Santala, M. I. K., Santos, B., Santucci, A., Sartori, F., Sartori, R., Sauter, O., Scannell, R., Schlummer, T., Schmid, K., Schmidt, V., Schmuck, S., Schneider, M., Schoepf, K., Schworer, D., Scott, S. D., Sergienko, G., Sertoli, M., Shabbir, A., Sharapov, S. E., Shaw, A., Shaw, R., Sheikh, H., Shepherd, A., Shevelev, A., Shumack, A., Sias, G., Sibbald, M., Sieglin, B., Silburn, S., Silva, A., Silva, C., Simmons, P. A., Simpson, J., Simpson-Hutchinson, J., Sinha, A., Sipila, S. K., Sips, A. C. C., Siren, P., Sirinelli, A., Sjostrand, H., Skiba, M., Skilton, R., Slabkowska, K., Slade, B., Smith, N., Smith, P. G., Smith, R., Smith, T. J., Smithies, M., Snoj, L., Soare, S., Solano, E. R., Somers, A., Sommariva, C., Sonato, P., Sopplesa, A., Sousa, J., Sozzi, C., Spagnolo, S., Spelzini, T., Spineanu, F., Stables, G., Stamatelatos, I., Stamp, M. F., Staniec, P., Stankunas, G., Stan-Sion, C., Stead, M. J., Stefanikova, E., Stepanov, I., Stephen, A. V., Stephen, M., Stevens, A., Stevens, B. D., Strachan, J., Strand, P., Strauss, H. R., Strom, P., Stubbs, G., Studholme, W., Subba, F., Summers, H. P., Svensson, J., Swiderski, L., Szabolics, T., Szawlowski, M., Szepesi, G., Suzuki, T. T., Tal, B., Tala, T., Talbot, A. R., Talebzadeh, S., Taliercio, C., Tamain, P., Tame, C., Tang, W., Tardocchi, M., Taroni, L., Taylor, D., Taylor, K. A., Tegnered, D., Telesca, G., Teplova, N., Terranova, D., Testa, D., Tholerus, E., Thomas, J., Thomas, J. D., Thomas, P., Thompson, A., Thompson, C. -A., Thompson, V. K., Thorne, L., Thornton, A., Thrysoe, A. S., Tigwell, P. A., Tipton, N., Tiseanu, I., Tojo, H., Tolias, P., Tomes, M., Tonner, P., Towndrow, M., Trimble, P., Tripsky, M., Tsalas, M., Tsavalas, P., Jun, D. Tskhakaya, Turner, I., Turner, M. M., Turnyanskiy, M., Tvalashvili, G., Tyrrell, S. G. J., Uccello, A., Ul-Abidin, Z., Uljanovs, J., Ulyatt, D., Urano, H., Uytdenhouwen, I., Vadgama, A. P., Valcarcel, D., Valentinuzzi, M., Valisa, M., Olivares, P. Vallejos, Valovic, M., Van De Mortel, M., Van Eester, D., Van Renterghem, W., van Rooij, G. J., Varje, J., Varoutis, S., Vartanian, S., Vasava, K., Vasilopoulou, T., Vega, J., Verdoolaege, G., Verhoeven, R., Verona, C., Rinati, G. Verona, Veshchev, E., Vianello, N., Vicente, J., Viezzer, E., Villari, S., Villone, F., Vincenzi, P., Vinyar, I., Viola, B., Vitins, A., Vizvary, Z., Vlad, M., Voitsekhovitch, I., Vondracek, P., Vora, N., Vu, T., Pires de Sa, W. W., Wakeling, B., Waldon, C. W. F., Walkden, N., Walker, M., Walker, R., Walsh, M., Wang, E., Wang, N., Warder, S., Warren, R. J., Waterhouse, J., Watkins, N. W., Watts, C., Wauters, T., Weckmann, A., Weiland, J., Weisen, H., Weiszflog, M., Wellstood, C., West, A. T., Wheatley, M. R., Whetham, S., Whitehead, A. M., Whitehead, B. D., Widdowson, A. M., Wiesen, S., Wilkinson, J., Williams, J., Williams, M., Wilson, A. R., Wilson, D. J., Wilson, H. R., Wilson, J., Wischmeier, M., Withenshaw, G., Withycombe, A., Witts, D. M., Wood, D., Wood, R., Woodley, C., Wray, S., Wright, J., Wright, J. C., Wu, J., Wukitch, S., Wynn, A., Xu, T., Yadikin, D., Yanling, W., Yao, L., Yavorskij, V., Yoo, M. G., Young, C., Young, D., Young, I. D., Young, R., Zacks, J., Zagorski, R., Zaitsev, F. S., Zanino, R., Zarins, A., Zastrow, K. D., Zerbini, M., Zhang, W., Zhou, Y., Zilli, E., Zoita, V., Zoletnik, S., Zychor, I., Department of Physics, Materials Physics, Universidad de Sevilla. Departamento de Física Atómica, Molecular y Nuclear, and Universidad de Sevilla. RNM138: Física Nuclear Aplicada
- Subjects
inorganic chemicals ,Nuclear and High Energy Physics ,Materials science ,analysis ,Materials Science (miscellaneous) ,JET-ILW ,Dust particles ,education ,Electron microprobe ,Tritium ,01 natural sciences ,114 Physical sciences ,010305 fluids & plasmas ,Nuclear physics ,Fusion, plasma och rymdfysik ,BERYLLIUM ,0103 physical sciences ,polycyclic compounds ,Imaging plate ,010306 general physics ,Jet (fluid) ,Electron prove microscopic ,organic chemicals ,Dust ,Fusion, Plasma and Space Physics ,lcsh:TK9001-9401 ,electron prove microscopic analysis ,Nuclear Energy and Engineering ,cardiovascular system ,Electron prove microscopic analysis ,lcsh:Nuclear engineering. Atomic power - Abstract
A tritium imaging plate technique (TIPT) in combination with an electron-probe microscopic analysis (EPMA) were applied to examine tritium (T) retention characteristics in individual dust particles collected in the Joint European Torus with the ITER-like Wall (JET-ILW) after the first campaign in 2011-2012., A lot of carbon (C)-dominated dust particles were found, which would be pre-existing carbon deposits in the JET-C or released carbon particles from the remaining carbon-fiber components in the JET-ILW. Most of T was retained at the surface of and/or in the C-dominated dust particles. The retention in tungsten, beryllium and other metal-dominated dust particles is relatively lower by a factor of 10-100 in comparison with that in the Cdominated particles.
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- 2018
7. Moral Distress and Moral Injury in Nephrology During the COVID-19 Pandemic
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Ducharlet, K, Trivedi, M, Gelfand, SL, Liew, H, McMahon, LP, Ashuntantang, G, Brennan, F, Brown, M, Martin, Dominique, Ducharlet, K, Trivedi, M, Gelfand, SL, Liew, H, McMahon, LP, Ashuntantang, G, Brennan, F, Brown, M, and Martin, Dominique
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- 2021
8. Propulsionless Planar Phasing of Multiple Satellites using Deep Reinforcement Learning
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Smith, B, Abay, R, Abbey, J, Brown, M, Boyce, R, Smith, B, Abay, R, Abbey, J, Brown, M, and Boyce, R
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- 2020
9. A Review of the Development and Applications of the Cuckoo Search Algorithm
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Walton, Sean, primary, Hassan, Oubay, additional, Morgan, Kenneth, additional, and Brown, M. Rowan, additional
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- 2013
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10. Liquid Chromatography in the Pharmaceutical Industry
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Szucs, R., primary, Brunelli, C., additional, Lestremau, F., additional, and Hanna-Brown, M., additional
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- 2013
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11. Contributors
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Alfonso, A., primary, Anguizola, J.A., additional, Barceló, Damia, additional, Baird, G., additional, Barnett, K.L., additional, Birbeck, J.A., additional, Bogialli, S., additional, Bosse, K.E., additional, Botana, A.M., additional, Botana, L.M., additional, Brunelli, C., additional, Caretti, F., additional, Castro-Puyana, M., additional, Chankvetadze, B., additional, Chen, B., additional, Cifuentes, A., additional, Diaz, Silvia, additional, Donato, P., additional, Dugo, P., additional, Eljarrat, Ethel, additional, Falkenhagen, J., additional, Farré, Marinella, additional, Gentili, A., additional, Giacometti, J., additional, Graul, T.W., additional, Hage, D.S., additional, Hamase, K., additional, Hanna-Brown, M., additional, Harpas, P., additional, Harrington, B., additional, Hernández, F., additional, Herrero, M., additional, Ibáñez, E., additional, Ibáñez, M., additional, Josić, D., additional, Koga, R., additional, Kostakis, C., additional, Lestremau, F., additional, Li, R., additional, Marazuela, M.D., additional, Mathews, T.A., additional, Matsuda, R., additional, Michalke, B., additional, Miyoshi, Y., additional, Mondello, L., additional, Newman, B.D., additional, Nischwitz, V., additional, Otero, P., additional, Oyama, T., additional, Papastavros, E., additional, Petrovic, Mira, additional, Pfaunmiller, E., additional, Poole, C.F., additional, Radke, W., additional, Rodríguez, P., additional, Royle, L., additional, Sander, L.C., additional, Schantz, M.M., additional, Shen, Y., additional, Sobansky, M., additional, Stockham, P., additional, Szucs, R., additional, van Beek, T.A., additional, Wise, S.A., additional, Zheng, X., additional, and Zuilhof, H., additional
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- 2013
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12. Audition
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Brown, M. Christian, primary and Santos-Sacchi, Joseph, additional
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- 2013
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13. Assessment in Schools – Mathematics
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Brown, M., primary and Hodgen, J., additional
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- 2010
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14. Safe process design and operation
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Brown, M., primary
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- 2009
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15. Contributor contact details
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Talbot, Geoff, primary, Beckett, S.T., additional, Yates, Philip, additional, Birkett, J., additional, Edwards, Bill, additional, Brown, M., additional, Cebula, D.J., additional, Hoddle, A., additional, Ziegler, G.R., additional, Subramaniam, Persis, additional, Wells, Martin, additional, Groves, Kathy, additional, Smith, K.W., additional, Richter, K., additional, Bean, M.J., additional, Geschwindner, G., additional, Drouven, H., additional, and Meyer, Joerg, additional
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- 2009
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16. Microbiological hazards and safe design
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Brown, M., primary
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- 2008
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17. Operation of plants manufacturing chilled foods
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Brown, M., primary
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- 2008
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18. Introduction to chilled foods
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Brown, M., primary
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- 2008
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19. Treatment-Related Emergencies in Feline Oncology
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Brown, M. Raquel, primary and Rogers, Kenita S., additional
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- 2006
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20. Supportive Medical Care and Pain Management in Feline Cancer Patients
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Brown, M. Raquel, primary and Rogers, Kenita S., additional
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- 2006
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21. Contributors
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Adams, Larry G., primary, Adams, Vicki J., additional, Atkins, Clarke E., additional, Bahr, Anne, additional, Baldwin, Claudia J., additional, Baral, Randolph, additional, Bartges, Joseph W., additional, Beale, Karin M., additional, Behrend, Ellen N., additional, Bergman, Robert L., additional, Bernstein, Penny L., additional, Brockus, Charles W., additional, Raquel Brown, M, additional, Tony Buffington, C.A, additional, Brad Case, J, additional, Center, Sharon A., additional, Chaffin, Kelly, additional, Chew, Dennis J., additional, Coates, Joan R., additional, Cowell, Rick L., additional, Crandell, John M., additional, DeBoer, Douglas J., additional, Dickinson, Peter J., additional, DiMarco, Anthony, additional, Dyer-Inzana, Karen, additional, Elliott, Jonathan, additional, Ferguson, Duncan C., additional, Fischer, Julie R., additional, Fleeman, Linda M., additional, Foley, Janet E., additional, Dru Forrester, S, additional, Fossum, Theresa W., additional, Foster, Aiden P., additional, Fox, Leslie E., additional, Fox, Philip R., additional, Freedman, Richard, additional, Gordon, Sonya G., additional, Green, Diane, additional, Griffin, Brenda, additional, Hale, Anne S., additional, Hoenig, Margarethe, additional, Hogan, Daniel F., additional, Hume, Kelly R., additional, Jergens, Albert E., additional, Johnson, Lynelle R., additional, Kirk, Claudia A., additional, Kline, Karen L., additional, Labato, Mary A., additional, Lane, India F., additional, Lappin, Michael R., additional, Levine, Jonathan M., additional, Litster, Annette L., additional, Lockwood, Randall, additional, Fuentes, Virginia Luis., additional, Lulich, Jody P., additional, Lurye, Jill C., additional, Lyon, Kenneth F., additional, Mackin, Andrew, additional, Malik, Richard, additional, Mansell, Joanne K., additional, Marks, Stanley L., additional, Meinkoth, James H., additional, Miller, Matthew W., additional, Moriello, Karen A., additional, Morris, Daniel O., additional, Norris, Jacqui M., additional, Andrew Novosad, C, additional, Olby, Natasha, additional, Osborne, Carl A., additional, Papich, Mark G., additional, Patel, Anita, additional, Paterson, Sue, additional, Peterson, Mark E., additional, Platt, Simon R., additional, Polzin, David J., additional, Powell, Cynthia C., additional, Pressler, Barrak, additional, Rand, Jacquie S., additional, Rees, Christine A., additional, Relford, Roberta L., additional, Rest, Joan R., additional, Rogers, Kenita S., additional, Roosje, Petra J., additional, Ross, Sheri J., additional, Ruaux, Craig G., additional, Scarlett, Janet M., additional, Schenck, Patricia A., additional, Sinclair, Leslie, additional, Slater, Margaret R., additional, Smith, Annette N., additional, Smith, Stephanie A., additional, Spangler, Elizabeth A., additional, Sturges, Beverly K., additional, Syme, Harriet M., additional, Tantillo, James A., additional, Tasker, Séverine, additional, Trepanier, Lauren A., additional, Tyler, Ronald D., additional, Vernau, Karen M., additional, Washabau, Robert J., additional, Westropp, Jodi L., additional, Willard, Michael D., additional, Wolf, Alice M., additional, Young, Karen M., additional, and Zoran, Debra L., additional
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- 2006
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22. Microbiological risk assessment for emerging pathogens
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Brown, M., primary and McClure, P., additional
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- 2006
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23. RF sheath modeling of experimentally observed plasma surface interactions with the JET ITER-Like Antenna
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JET Contributors, Krivska, A., Bobkov, V., Colas, L., Dumortier, P., Durodie, F., Jacquet, P., Klepper, C. C., Milanesio, D., Urbanczyk, G., Abduallev, S., Abhangi, M., Abreu, P., Afzal, M., Aggarwal, K. M., Ahlgren, T., Ahn, J. H., Aho-Mantila, L., Aiba, N., Airila, M., Albanese, R., Aldred, V., Alegre, D., Alessi, E., Aleynikov, P., Alfier, A., Alkseev, A., Allinson, M., Alper, B., Alves, E., Ambrosino, G., Ambrosino, R., Amicucci, L., Amosov, V., Sunden, E. Andersson, Angelone, M., Anghel, M., Angioni, C., Appel, L., Appelbee, C., Arena, P., Ariola, M., Arnichand, H., Arshad, S., Ash, A., Ashikawa, N., Aslanyan, V., Asunta, O., Auriemma, F., Austin, Y., Avotina, L., Axton, M. D., Ayres, C., Bacharis, M., Baciero, A., Baiao, D., Bailey, S., Baker, A., Balboa, I., Balden, M., Balshaw, N., Bament, R., Banks, J. W., Baranov, Y. F., Barnard, M. A., Barnes, D., Barnes, M., Barnsley, R., Wiechec, A. Baron, Orte, L. Barrera, Baruzzo, M., Basiuk, V., Bassan, M., Bastow, R., Batista, A., Batistoni, P., Baughan, R., Bauvir, B., Baylor, L., Bazylev, B., Beal, J., Beaumont, P. S., Beckers, M., Beckett, B., Becoulet, A., Bekris, N., Beldishevski, M., Bell, K., Belli, F., Bellinger, M., Belonohy, E., Ben Ayed, N., Benterman, N. A., Bergsaker, H., Bernardo, J., Bernert, M., Berry, M., Bertalot, L., Besliu, C., Beurskens, M., Bieg, B., Bielecki, J., Biewer, T., Bigi, M., Bilkova, P., Binda, F., Bisoffi, A., Bizarro, J. P. S., Bjorkas, C., Blackburn, J., Blackman, K., Blackman, T. R., Blanchard, P., Blatchford, P., Boboc, A., Bodnar, G., Bogar, O., Bolshakova, I., Bolzonella, T., Bonanomi, N., Bonelli, F., Boom, J., Booth, J., Borba, D., Borodin, D., Borodkina, I., Botrugno, A., Bottereau, C., Boulting, P., Bourdelle, C., Bowden, M., Bower, C., Bowman, C., Boyce, T., Boyd, C., Boyer, H. J., Bradshaw, J. M. A., Braic, V., Bravanec, R., Breizman, B., Bremond, S., Brennan, P. D., Breton, S., Brett, A., Brezinsek, S., Bright, M. D. J., Brix, M., Broeckx, W., Brombin, M., Broslawski, A., Brown, D. P. D., Brown, M., Bruno, E., Bucalossi, J., Buch, J., Buchanan, J., Buckley, M. A., Budny, R., Bufferand, H., Bulman, M., Bulmer, N., Bunting, P., Buratti, P., Burckhart, A., Buscarino, A., Busse, A., Butler, N. K., Bykov, I., Byrne, J., Cahyna, P., Calabro, G., Calvo, I., Camenen, Y., Camp, P., Campling, D. C., Cane, J., Cannas, B., Capel, A. J., Card, P. J., Cardinali, A., Carman, P., Carr, M., Carralero, D., Carraro, L., Carvalho, B. B., Carvalho, I., Carvalho, P., Casson, F. J., Castaldo, C., Catarino, N., Caumont, J., Causa, F., Cavazzana, R., Cave-Ayland, K., Cavinato, M., Cecconello, M., Ceccuzzi, S., Cecil, E., Cenedese, A., Cesario, R., Challis, C. D., Chandler, M., Chandra, D., Chang, C. S., Chankin, A., Chapman, I. T., Chapman, S. C., Chernyshova, M., Chitarin, G., Ciraolo, G., Ciric, D., Citrin, J., Clairet, F., Clark, E., Clark, M., Clarkson, R., Clatworthy, D., Clements, C., Cleverly, M., Coad, J. P., Coates, P. A., Cobalt, A., Coccorese, V., Cocilovo, V., Coda, S., Coelho, R., Coenen, J. W., Coffey, I., Collins, S., Conka, D., Conroy, S., Conway, N., Coombs, D., Cooper, D., Cooper, S. R., Corradino, C., Corre, Y., Corrigan, G., Cortes, S., Coster, D., Couchman, A. S., Cox, M. P., Craciunescu, T., Cramp, S., Craven, R., Crisanti, F., Croci, G., Croft, D., Crombe, K., Crowe, R., Cruz, N., Cseh, G., Cufar, A., Cullen, A., Curuia, M., Czarnecka, A., Dabirikhah, H., Dalgliesh, P., Dalley, S., Dankowski, J., Darrow, D., Davies, O., Davis, W., Day, C., Day, I. E., De Bock, M., Castro, A. de, Cal, E. de la, Luna, E. de la, De Masi, G., Pablos, J. L. de, Temmerman, G., De, De Tommasi, G., Vries, P. de, Deakin, K., Deane, J., Agostini, F. Degli, Dejarnac, R., Delabie, E., Harder, N. den, Dendy, R. O., Denis, J., Denner, P., Devaux, S., Devynck, P., Di Maio, F., Di Siena, A., Di Troia, C., Dinca, P., D’Inca, R., Ding, B., Dittmar, T., Doerk, H., Doerner, R. P., Donne, T., Dorling, S. E., Dormido-Canto, S., Doswon, S., Douai, D., Doyle, P. T., Drenik, A., Drewelow, P., Drews, P., Duckworth, Ph, Dumont, R., Dunai, D., Dunne, M., Duran, I., Dutta, P., Duval, B. P., Dux, R., Dylst, K., Dzysiuk, N., Edappala, P. V., Edmond, J., Edwards, A. M., Edwards, J., Eich, Th, Ekedahl, A., El-Jorf, R., Elsmore, C. G., Enachescu, M., Ericsson, G., Eriksson, F., Eriksson, J., Eriksson, L. G., Esposito, B., Esquembri, S., Esser, H. G., Esteve, D., Evans, B., Evans, G. E., Evison, G., Ewart, G. D., Fagan, D., Faitsch, M., Falie, D., Fanni, A., Fasoli, A., Faustin, J. M., Fawlk, N., Fazendeiro, L., Fedorczak, N., Felton, R. C., Fenton, K., Fernades, A., Fernandes, H., Ferreira, J., Fessey, J. A., Fevrier, O., Ficker, O., Field, A., Fietz, S., Figueiredo, A., Figueiredo, J., Fil, A., Finburg, P., Firdaouss, M., Fischer, U., Fittill, L., Fitzgerald, M., Flammini, D., Flanagan, J., Fleming, C., Flinders, K., Fonnesu, N., Fontdecaba, J. M., Formisano, A., Forsythe, L., Fortuna, L., Fortuna-Zalesna, E., Fortune, M., Foster, S., Franke, T., Franklin, T., Frasca, M., Frassinetti, L., Freisinger, M., Fresa, R., Frigione, D., Fuchs, V., Fuller, D., Futatani, S., Fyvie, J., Gal, K., Galassi, D., Galazka, K., Galdon-Quiroga, J., Gallagher, J., Gallart, D., Galvao, R., Gao, X., Gao, Y., Garcia, J., Garcia-Carrasco, A., Garcia-Munoz, M., Gardarein, J.-L., Garzotti, L., Gaudio, P., Gauthier, E., Gear, D. F., Gee, S. J., Geiger, B., Gelfusa, M., Gerasimov, S., Gervasini, G., Gethins, M., Ghani, Z., Ghate, M., Gherendi, M., Giacalone, J. C., Giacomelli, L., Gibson, C. S., Giegerich, T., Gil, C., Gil, L., Gilligan, S., Gin, D., Giovannozzi, E., Girardo, J. B., Giroud, C., Giruzzi, G., Gloeggler, S., Godwin, J., Goff, J., Gohil, P., Goloborod’ko, V., Gomes, R., Goncalves, B., Goniche, M., Goodliffe, M., Goodyear, A., Gorini, G., Gosk, M., Goulding, R., Goussarov, A., Gowland, R., Graham, B., Graham, M. E., Graves, J. P., Grazier, N., Grazier, P., Green, N. R., Greuner, H., Grierson, B., Griph, F. S., Grisolia, C., Grist, D., Groth, M., Grove, R., Grundy, C. N., Grzonka, J., Guard, D., Guerard, C., Guillemaut, C., Guirlet, R., Gurl, C., Utoh, H. H., Hackett, L. J., Hacquin, S., Hagar, A., Hager, R., Hakola, A., Halitovs, M., Hall, S. J., Cook, S. P. Hallworth, Hamlyn-Harris, C., Hammond, K., Harrington, C., Harrison, J., Harting, D., Hasenbeck, F., Hatano, Y., Hatch, D. R., Haupt, T. D. V., Hawes, J., Hawkes, N. C., Hawkins, J., Hawkins, P., Haydon, P. W., Hayter, N., Hazel, S., Heesterman, P. J. L., Heinola, K., Hellesen, C., Hellsten, T., Helou, W., Hemming, O. N., Hender, T. C., Henderson, M., Henderson, S. S., Henriques, R., Hepple, D., Hermon, G., Hertout, P., Hidalgo, C., Highcock, E. G., Hill, M., Hillairet, J., Hillesheim, J., Hillis, D., Hizanidis, K., Hjalmarsson, A., Hobirk, J., Hodille, E., Hogben, C. H. A., Hogeweij, G. M. D., Hollingsworth, A., Hollis, S., Homfray, D. A., Horacek, J., Hornung, G., Horton, A. R., Horton, L. D., Horvath, L., Hotchin, S. P., Hough, M. R., Howarth, P. J., Hubbard, A., Huber, A., Huber, V., Huddleston, T. M., Hughes, M., Huijsmans, G. T. A., Hunter, C. L., Huynh, P., Hynes, A. M., Iglesias, D., Imazawa, N., Imbeaux, F., Imrisek, M., Incelli, M., Innocente, P., Irishkin, M., Ivanova-Stanik, I., Jachmich, S., Jacobsen, A. S., Jansons, J., Jardin, A., Jarvinen, A., Jaulmes, F., Jednorog, S., Jenkins, I., Jeong, C., Jepu, I., Joffrin, E., Johnson, R., Johnson, T., Johnston, Jane, Joita, L., Jones, G., Jones, T. T. C., Hoshino, K. 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E., Mantica, P., Mantsinen, M., Manzanares, A., Maquet, Ph, Marandet, Y., Marcenko, N., Marchetto, C., Marchuk, O., Marinelli, M., Marinucci, M., Markovic, T., Marocco, D., Marot, L., Marren, C. A., Marshal, R., Martin, A., Martin, Y., Martin de Aguilera, A., Martinez, F. J., Martin-Solis, J. R., Martynova, Y., Maruyama, S., Masiello, A., Maslov, M., Matejcik, S., Mattei, M., Matthews, G. F., Maviglia, F., Mayer, M., Mayoral, M. L., May-Smith, T., Mazon, D., Mazzotta, C., McAdams, R., McCarthy, P. J., McClements, K. G., McCormack, O., McCullen, P. A., McDonald, D., McIntosh, S., McKean, R., McKehon, J., Meadows, R. C., Meakins, A., Medina, F., Medland, M., Medley, S., Meigh, S., Meigs, A. G., Meisl, G., Meitner, S., Meneses, L., Menmuir, S., Mergia, K., Merrigan, I. R., Mertens, Ph, Meshchaninov, S., Messiaen, A., Meyer, H., Mianowski, S., Michling, R., Middleton-Gear, D., Miettunen, J., Militello, F., Militello-Asp, E., Miloshevsky, G., Mink, F., Minucci, S., Miyoshi, Y., Mlynar, J., Molina, D., Monakhov, I., Moneti, M., Mooney, R., Moradi, S., Mordijck, S., Moreira, L., Moreno, R., Moro, F., Morris, A. W., Morris, J., Moser, L., Mosher, S., Moulton, D., Murari, A., Muraro, A., Murphy, S., Asakura, N. N., Na, Y. S., Nabais, F., Naish, R., Nakano, T., Nardon, E., Naulin, V., Nave, M. F. F., Nedzelski, I., Nemtsev, G., Nespoli, F., Neto, A., Neu, R., Neverov, V. S., Newman, M., Nicholls, K. J., Nicolas, T., Nielsen, A. H., Nielsen, P., Nilsson, E., Nishijima, D., Noble, C., Nocente, M., Nodwell, D., Nordlund, K., Nordman, H., Nouailletas, R., Nunes, I., Oberkofler, M., Odupitan, T., Ogawa, M. T., O’Gorman, T., Okabayashi, M., Olney, R., Omolayo, O., O’Mullane, M., Ongena, J., Orsitto, F., Orszagh, J., Oswuigwe, B. I., Otin, R., Owen, A., Paccagnella, R., Pace, N., Pacella, D., Packer, L. W., Page, A., Pajuste, E., Palazzo, S., Pamela, S., Panja, S., Papp, P., Paprok, R., Parail, V., Park, M., Diaz, F. Parra, Parsons, M., Pasqualotto, R., Patel, A., Pathak, S., Paton, D., Patten, H., Pau, A., Pawelec, E., Soldan, C. Paz, Peackoc, A., Pearson, I. J., Pehkonen, S.-P., Peluso, E., Penot, C., Pereira, A., Pereira, R., Puglia, P. P. Pereira, Thun, C. Perez von, Peruzzo, S., Peschanyi, S., Peterka, M., Petersson, P., Petravich, G., Petre, A., Petrella, N., Petrzilka, V., Peysson, Y., Pfefferle, D., Philipps, V., Pillon, M., Pintsuk, G., Piovesan, P., Pires dos Reis, A., Piron, L., Pironti, A., Pisano, F., Pitts, R., Pizzo, F., Plyusnin, V., Pomaro, N., Pompilian, O. G., Pool, P. J., Popovichev, S., Porfiri, M. T., Porosnicu, C., Porton, M., Possnert, G., Potzel, S., Powell, T., Pozzi, J., Prajapati, V., Prakash, R., Prestopino, G., Price, D., Price, M., Price, R., Prior, P., Proudfoot, R., Pucella, G., Puglia, P., Puiatti, M. E., Pulley, D., Purahoo, K., Puetterich, Th, Rachlew, E., Rack, M., Ragona, R., Rainford, M. S. J., Rakha, A., Ramogida, G., Ranjan, S., Rapson, C. J., Rasmussen, J. J., Rathod, K., Ratta, G., Ratynskaia, S., Ravera, G., Rayner, C., Rebai, M., Reece, D., Reed, A., Refy, D., Regan, B., Regana, J., Reich, M., Reid, N., Reimold, F., Reinhart, M., Reinke, M., Reiser, D., Rendell, D., Reux, C., Reyes Cortes, S. D. A., Reynolds, S., Riccardo, V., Richardson, N., Riddle, K., Rigamonti, D., Rimini, F. G., Risner, J., Riva, M., Roach, C., Robins, R. J., Robinson, S. A., Robinson, T., Robson, D. W., Roccella, R., Rodionov, R., Rodrigues, P., Rodriguez, J., Rohde, V., Romanelli, F., Romanelli, M., Romanelli, S., Romazanov, J., Rowe, S., Rubel, M., Rubinacci, G., Rubino, G., Ruchko, L., Ruiz, M., Ruset, C., Rzadkiewicz, J., Saarelma, S., Sabot, R., Safi, E., Sagar, P., Saibene, G., Saint-Laurent, F., Salewski, M., Salmi, A., Salmon, R., Salzedas, F., Samaddar, D., Samm, U., Sandiford, D., Santa, P., Santala, M. I. K., Santos, B., Santucci, A., Sartori, F., Sartori, R., Sauter, O., Scannell, R., Schlummer, T., Schmid, K., Schmidt, V., Schmuck, S., Schneider, M., Schoepf, K., Schworer, D., Scott, S. D., Sergienko, G., Sertoli, M., Shabbir, A., Sharapov, S. E., Shaw, A., Shaw, R., Sheikh, H., Shepherd, A., Shevelev, A., Shumack, A., Sias, G., Sibbald, M., Sieglin, B., Silburn, S., Silva, A., Silva, C., Simmons, P. A., Simpson, J., Simpson-Hutchinson, J., Sinha, A., Sipila, S. K., Sips, A. C. C., Siren, P., Sirinelli, A., Sjostrand, H., Skiba, M., Skilton, R., Slabkowska, K., Slade, B., Smith, N., Smith, P. G., Smith, R., Smith, T. J., Smithies, M., Snoj, L., Soare, S., Solano, E. R., Somers, A., Sommariva, C., Sonato, P., Sopplesa, A., Sousa, J., Sozzi, C., Spagnolo, S., Spelzini, T., Spineanu, F., Stables, G., Stamatelatos, I., Stamp, M. F., Staniec, P., Stankunas, G., Stan-Sion, C., Stead, M. J., Stefanikova, E., Stepanov, I., Stephen, A. V., Stephen, M., Stevens, A., Stevens, B. D., Strachan, J., Strand, P., Strauss, H. R., Strom, P., Stubbs, G., Studholme, W., Subba, F., Summers, H. P., Svensson, J., Swiderski, L., Szabolics, T., Szawlowski, M., Szepesi, G., Suzuki, T. T., Tal, B., Tala, T., Talbot, A. R., Talebzadeh, S., Taliercio, C., Tamain, P., Tame, C., Tang, W., Tardocchi, M., Taroni, L., Taylor, D., Taylor, K. A., Tegnered, D., Telesca, G., Teplova, N., Terranova, D., Testa, D., Tholerus, E., Thomas, J., Thomas, J. D., Thomas, P., Thompson, A., Thompson, C.-A., Thompson, V. K., Thorne, L., Thornton, A., Thrysoe, A. S., Tigwell, P. A., Tipton, N., Tiseanu, I., Tojo, H., Tokitani, M., Tolias, P., Tomes, M., Tonner, P., Towndrow, M., Trimble, P., Tripsky, M., Tsalas, M., Tsavalas, P., Jun, D. Tskhakaya, Turner, I., Turner, M. M., Turnyanskiy, M., Tvalashvili, G., Tyrrell, S. G. J., Uccello, A., Ul-Abidin, Z., Uljanovs, J., Ulyatt, D., Urano, H., Uytdenhouwen, I., Vadgama, A. P., Valcarcel, D., Valentinuzzi, M., Valisa, M., Olivares, P. Vallejos, Valovic, M., Van De Mortel, M., Van Eester, D., Van Renterghem, W., Rooij, G. J. van, Varje, J., Varoutis, S., Vartanian, S., Vasava, K., Vasilopoulou, T., Vega, J., Verdoolaege, G., Verhoeven, R., Verona, C., Rinati, G. Verona, Veshchev, E., Vianello, N., Vicente, J., Viezzer, E., Villari, S., Villone, F., Vincenzi, P., Vinyar, I., Viola, B., Vitins, A., Vizvary, Z., Vlad, M., Voitsekhovitch, I., Vondracek, P., Vora, N., Vu, T., Pires de Sa, W. W., Wakeling, B., Waldon, C. W. F., Walkden, N., Walker, M., Walker, R., Walsh, M., Wang, E., Wang, N., Warder, S., Warren, R. J., Waterhouse, J., Watkins, N. W., Watts, C., Wauters, T., Weckmann, A., Weiland, J., Weisen, H., Weiszflog, M., Wellstood, C., West, A. T., Wheatley, M. R., Whetham, S., Whitehead, A. M., Whitehead, B. D., Widdowson, A. M., Wiesen, S., Wilkinson, J., Williams, J., Williams, M., Wilson, A. R., Wilson, D. J., Wilson, H. R., Wilson, J., Wischmeier, M., Withenshaw, G., Withycombe, A., Witts, D. M., Wood, D., Wood, R., Woodley, C., Wray, S., Wright, J., Wright, J. C., Wu, J., Wukitch, S., Wynn, A., Xu, T., Yadikin, D., Yanling, W., Yao, L., Yavorskij, V., Yoo, M. G., Young, C., Young, D., Young, I. D., Young, R., Zacks, J., Zagorski, R., Zaitsev, F. S., Zanino, R., Zarins, A., Zastrow, K. D., Zerbini, M., Zhang, W., Zhou, Y., Zilli, E., Zoita, V., Zoletnik, S., Zychor, I., Universidad de Sevilla. Departamento de Física Atómica, Molecular y Nuclear, Universidad de Sevilla. RNM138: Física Nuclear Aplicada, JET Contributors, Materials Physics, and Department of Physics
- Subjects
Nuclear and High Energy Physics ,Technology and Engineering ,Materials science ,Materials Science (miscellaneous) ,design ,Cyclotron ,114 Physical sciences ,01 natural sciences ,7. Clean energy ,010305 fluids & plasmas ,law.invention ,Ion ,Fusion, plasma och rymdfysik ,DESIGN ,icrf ,law ,Physics::Plasma Physics ,0103 physical sciences ,ddc:530 ,Antenna arrays ,010306 general physics ,Jet (fluid) ,Range (particle radiation) ,Plasma surface ,ICRF ,Physics ,Fusion, Plasma and Space Physics ,lcsh:TK9001-9401 ,Nuclear Energy and Engineering ,Physics::Space Physics ,lcsh:Nuclear engineering. Atomic power ,Antenna (radio) ,Atomic physics - Abstract
Waves in the Ion Cyclotron Range of Frequencies (ICRF) enhance local Plasma-Surface Interactions (PSI) near the wave launchers and magnetically-connected objects via Radio-Frequency (RF) sheath rectification. ITER will use 20MW of ICRF power over long pulses, questioning the long-term impact of RF-enhanced localized erosion on the lifetime of its Beryllium (Be) wall. Recent dedicated ICRF-heated L-mode discharges documented this process on JET for different types of ICRF antennas. Using visible spectroscopy in JET ICRF-heated L-mode discharges, poloidally-localized regions of enhanced (by similar to 2-4x) Be I and Be II light emission were observed on two outboard limiters magnetically connected to the bottom of the active ITER-Like Antenna (ILA). The observed RF-PSI induced by the ILA was qualitatively comparable to that induced by the JET standard, type-A2 antennas, for similar strap toroidal phasing and connection geometries. The Be II line emission was found more intense when powering the bottom half of the ILA rather than its top half. Conversely, more pronounced SOL density modifications were observed with only top array operation, on field lines connected to the top half of the ILA. So far the near-field modeling of the ILA with antenna code TOPICA (Torino Polytechnic Ion Cyclotron Antenna), using curved antenna model, was partially able to reproduce qualitatively the observed phenomena. A quantitative discrepancy persisted between the observed Be source amplification and the calculated, corresponding increases in E-// field at the magnetically connected locations to the ILA when changing from only top to only bottom half antenna operation. This paper revisits these current drive phased and half-ILA powered cases using for the new simulations flat model of the ILA and more realistic antenna feeding to calculate the E-// field maps with TOPICA code. Further, the Self-consistent Sheaths and Waves for Ion Cyclotron Heating Slow Wave (SSWICH-SW) code, which couples slow wave evanescence with DC Scrape-Off Layer (SOL) biasing, is used to estimate the poloidal distribution of rectified RF-sheath Direct Current (DC) potential V-DC in the private SOL between the ILA poloidal limiters. The approach so far was limited to correlating the observed, enhanced emission regions at the remote limiters to the antenna near-electric fields, as calculated by TOPICA. The present approach includes also a model for the rectification of these near-fields in the private SOL of the ILA. With the improved approach, when comparing only top and only bottom half antenna feeding, we obtained good qualitative correlation between all experimental measurements and the calculated local variations in the E-// field and V-DC potential. For complete list of authors see http://dx.doi.org/10.1016/j.nme.2019.03.009
- Published
- 2019
24. Improved ERO modelling of beryllium erosion at ITER upper first wall panel using JET-ILW and PISCES-B experience
- Author
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JET Contributors, Borodin, D., Romazanov, J., Pitts, R. A., Lisgo, S. W., Brezinsek, S., Borodkina, I., Eksaeva, A., Safi, E., Nordlund, K., Kirschner, A., Linsmeier, Ch, Abduallev, S., Abhangi, M., Abreu, P., Afzal, M., Aggarwal, K. M., Ahlgren, T., Ahn, J. H., Aho-Mantila, L., Aiba, N., Airila, M., Albanese, R., Aldred, V., Alegre, D., Alessi, E., Aleynikov, P., Alfier, A., Alkseev, A., Allinson, M., Alper, B., Alves, E., Ambrosino, G., Ambrosino, R., Amicucci, L., Amosov, V., Sunden, E. Andersson, Angelone, M., Anghel, M., Angioni, C., Appel, L., Appelbee, C., Arena, P., Ariola, M., Arnichand, H., Arshad, S., Ash, A., Ashikawa, N., Aslanyan, V., Asunta, O., Auriemma, F., Austin, Y., Avotina, L., Axton, M. D., Ayres, C., Bacharis, M., Baciero, A., Baiao, D., Bailey, S., Baker, A., Balboa, I., Balden, M., Balshaw, N., Bament, R., Banks, J. W., Baranov, Y. F., Barnard, M. A., Barnes, D., Barnes, M., Barnsley, R., Wiechec, A. Baron, Orte, L. Barrera, Baruzzo, M., Basiuk, V., Bassan, M., Bastow, R., Batista, A., Batistoni, P., Baughan, R., Bauvir, B., Baylor, L., Bazylev, B., Beal, J., Beaumont, P. S., Beckers, M., Beckett, B., Becoulet, A., Bekris, N., Beldishevski, M., Bell, K., Belli, F., Bellinger, M., Belonohy, E., Ben Ayed, N., Benterman, N. A., Bergsaker, H., Bernardo, J., Bernert, M., Berry, M., Bertalot, L., Besliu, C., Beurskens, M., Bieg, B., Bielecki, J., Biewer, T., Bigi, M., Bilkova, P., Binda, F., Bisoffi, A., Bizarro, J. P. S., Bjorkas, C., Blackburn, J., Blackman, K., Blackman, T. R., Blanchard, P., Blatchford, P., Bobkov, V., Boboc, A., Bodnar, G., Bogar, O., Bolshakova, I., Bolzonella, T., Bonanomi, N., Bonelli, F., Boom, J., Booth, J., Borba, D., Botrugno, A., Bottereau, C., Boulting, P., Bourdelle, C., Bowden, M., Bower, C., Bowman, C., Boyce, T., Boyd, C., Boyer, H. J., Bradshaw, J. M. A., Braic, V., Bravanec, R., Breizman, B., Bremond, S., Brennan, P. D., Breton, S., Brett, A., Bright, M. D. J., Brix, M., Broeckx, W., Brombin, M., Broslawski, A., Brown, D. P. D., Brown, M., Bruno, E., Bucalossi, J., Buch, J., Buchanan, J., Buckley, M. A., Budny, R., Bufferand, H., Bulman, M., Bulmer, N., Bunting, P., Buratti, P., Burckhart, A., Buscarino, A., Busse, A., Butler, N. K., Bykov, I., Byrne, J., Cahyna, P., Calabro, G., Calvo, I., Camenen, Y., Camp, P., Campling, D. C., Cane, J., Cannas, B., Capel, A. J., Card, P. J., Cardinali, A., Carman, P., Carr, M., Carralero, D., Carraro, L., Carvalho, B. B., Carvalho, I., Carvalho, P., Casson, F. J., Castaldo, C., Catarino, N., Caumont, J., Causa, F., Cavazzana, R., Cave-Ayland, K., Cavinato, M., Cecconello, M., Ceccuzzi, S., Cecil, E., Cenedese, A., Cesario, R., Challis, C. D., Chandler, M., Chandra, D., Chang, C. S., Chankin, A., Chapman, I. T., Chapman, S. C., Chernyshova, M., Chitarin, G., Ciraolo, G., Ciric, D., Citrin, J., Clairet, F., Clark, E., Clark, M., Clarkson, R., Clatworthy, D., Clements, C., Cleverly, M., Coad, J. 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E., Mantica, P., Mantsinen, M., Manzanares, A., Maquet, Ph, Marandet, Y., Marcenko, N., Marchetto, C., Marchuk, O., Marinelli, M., Marinucci, M., Markovic, T., Marocco, D., Marot, L., Marren, C. A., Marshal, R., Martin, A., Martin, Y., Martin de Aguilera, A., Martinez, F. J., Martin-Solis, J. R., Martynova, Y., Maruyama, S., Masiello, A., Maslov, M., Matejcik, S., Mattei, M., Matthews, G. F., Maviglia, F., Mayer, M., Mayoral, M. L., May-Smith, T., Mazon, D., Mazzotta, C., McAdams, R., McCarthy, P. J., McClements, K. G., McCormack, O., McCullen, P. A., McDonald, D., McIntosh, S., McKean, R., McKehon, J., Meadows, R. C., Meakins, A., Medina, F., Medland, M., Medley, S., Meigh, S., Meigs, A. G., Meisl, G., Meitner, S., Meneses, L., Menmuir, S., Mergia, K., Merrigan, I. R., Mertens, Ph, Meshchaninov, S., Messiaen, A., Meyer, H., Mianowski, S., Michling, R., Middleton-Gear, D., Miettunen, J., Militello, F., Militello-Asp, E., Miloshevsky, G., Mink, F., Minucci, S., Miyoshi, Y., Mlynar, J., Molina, D., Monakhov, I., Moneti, M., Mooney, R., Moradi, S., Mordijck, S., Moreira, L., Moreno, R., Moro, F., Morris, A. W., Morris, J., Moser, L., Mosher, S., Moulton, D., Murari, A., Muraro, A., Murphy, S., Asakura, N. N., Na, Y. S., Nabais, F., Naish, R., Nakano, T., Nardon, E., Naulin, V., Nave, M. F. F., Nedzelski, I., Nemtsev, G., Nespoli, F., Neto, A., Neu, R., Neverov, V. S., Newman, M., Nicholls, K. J., Nicolas, T., Nielsen, A. H., Nielsen, P., Nilsson, E., Nishijima, D., Noble, C., Nocente, M., Nodwell, D., Nordman, H., Nouailletas, R., Nunes, I., Oberkofler, M., Odupitan, T., Ogawa, M. T., O’Gorman, T., Okabayashi, M., Olney, R., Omolayo, O., O’Mullane, M., Ongena, J., Orsitto, F., Orszagh, J., Oswuigwe, B. I., Otin, R., Owen, A., Paccagnella, R., Pace, N., Pacella, D., Packer, L. W., Page, A., Pajuste, E., Palazzo, S., Pamela, S., Panja, S., Papp, P., Paprok, R., Parail, V., Park, M., Diaz, F. Parra, Parsons, M., Pasqualotto, R., Patel, A., Pathak, S., Paton, D., Patten, H., Pau, A., Pawelec, E., Soldan, C. Paz, Peackoc, A., Pearson, I. J., Pehkonen, S.-P., Peluso, E., Penot, C., Pereira, A., Pereira, R., Puglia, P. P. Pereira, Thun, C. Perez von, Peruzzo, S., Peschanyi, S., Peterka, M., Petersson, P., Petravich, G., Petre, A., Petrella, N., Petrzilka, V., Peysson, Y., Pfefferle, D., Philipps, V., Pillon, M., Pintsuk, G., Piovesan, P., Pires dos Reis, A., Piron, L., Pironti, A., Pisano, F., Pitts, R., Pizzo, F., Plyusnin, V., Pomaro, N., Pompilian, O. G., Pool, P. J., Popovichev, S., Porfiri, M. 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W., Roccella, R., Rodionov, R., Rodrigues, P., Rodriguez, J., Rohde, V., Romanelli, F., Romanelli, M., Romanelli, S., Rowe, S., Rubel, M., Rubinacci, G., Rubino, G., Ruchko, L., Ruiz, M., Ruset, C., Rzadkiewicz, J., Saarelma, S., Sabot, R., Sagar, P., Saibene, G., Saint-Laurent, F., Salewski, M., Salmi, A., Salmon, R., Salzedas, F., Samaddar, D., Samm, U., Sandiford, D., Santa, P., Santala, M. I. K., Santos, B., Santucci, A., Sartori, F., Sartori, R., Sauter, O., Scannell, R., Schlummer, T., Schmid, K., Schmidt, V., Schmuck, S., Schneider, M., Schoepf, K., Schworer, D., Scott, S. D., Sergienko, G., Sertoli, M., Shabbir, A., Sharapov, S. E., Shaw, A., Shaw, R., Sheikh, H., Shepherd, A., Shevelev, A., Shumack, A., Sias, G., Sibbald, M., Sieglin, B., Silburn, S., Silva, A., Silva, C., Simmons, P. A., Simpson, J., Simpson-Hutchinson, J., Sinha, A., Sipila, S. K., Sips, A. C. 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W., Wakeling, B., Waldon, C. W. F., Walkden, N., Walker, M., Walker, R., Walsh, M., Wang, E., Wang, N., Warder, S., Warren, R. J., Waterhouse, J., Watkins, N. W., Watts, C., Wauters, T., Weckmann, A., Weiland, J., Weisen, H., Weiszflog, M., Wellstood, C., West, A. T., Wheatley, M. R., Whetham, S., Whitehead, A. M., Whitehead, B. D., Widdowson, A. M., Wiesen, S., Wilkinson, J., Williams, J., Williams, M., Wilson, A. R., Wilson, D. J., Wilson, H. R., Wilson, J., Wischmeier, M., Withenshaw, G., Withycombe, A., Witts, D. M., Wood, D., Wood, R., Woodley, C., Wray, S., Wright, J., Wright, J. C., Wu, J., Wukitch, S., Wynn, A., Xu, T., Yadikin, D., Yanling, W., Yao, L., Yavorskij, V., Yoo, M. G., Young, C., Young, D., Young, I. D., Young, R., Zacks, J., Zagorski, R., Zaitsev, F. S., Zanino, R., Zarins, A., Zastrow, K. D., Zerbini, M., Zhang, W., Zhou, Y., Zilli, E., Zoita, V., Zoletnik, S., Zychor, I., Universidad de Sevillla. Departamento de Física Atómica, Molecular y Nuclear, Universidad de Sevilla. RNM138: Física Nuclear Aplicada, Department of Physics, and Materials Physics
- Subjects
Nuclear and High Energy Physics ,Technology and Engineering ,Materials science ,Tokamak ,JET ITER-like wall ,Materials Science (miscellaneous) ,Nuclear engineering ,design ,chemistry.chemical_element ,Blanket ,01 natural sciences ,114 Physical sciences ,deposition ,Modelling ,010305 fluids & plasmas ,law.invention ,ITER first wall ,Fusion, plasma och rymdfysik ,DESIGN ,law ,Sputtering ,0103 physical sciences ,Deposition (phase transition) ,ddc:530 ,DEPOSITION ,plasma ,010302 applied physics ,Jet (fluid) ,PLASMA ,Physics ,Plasma ,lcsh:TK9001-9401 ,Fusion, Plasma and Space Physics ,Nuclear Energy and Engineering ,chemistry ,Deuterium ,Erosion ,ERO code ,lcsh:Nuclear engineering. Atomic power ,Beryllium ,ddc:624 - Abstract
ERO is a 3D Monte-Carlo impurity transport and plasma-surface interaction code. In 2011 it was applied for the ITER first wall (FW) life time predictions [1] (critical blanket module BM11). After that the same code was significantly improved during its application to existing fusion-relevant plasma devices: the tokamak JET equipped with an ITER-like wall and linear plasma device PISCES-B. This has allowed testing the sputtering data for beryllium (Be) and showing that the “ERO-min” fit based on the large (50%) deuterium (D) surface content is well suitable for plasma-wetted areas (D plasma). The improved procedure for calculating of the effective sputtering yields for each location along the plasma-facing surface using the recently developed semi-analytical sheath approach was validated. The re-evaluation of the effective yields for BM11 following the similar revisit of the JET data has indicated significant increase of erosion and motivated the current re-visit of ERO simulations. Keywords: Beryllium, Erosion, ITER first wall, JET ITER-like wall, ERO code, Modelling
- Published
- 2019
25. The effect of beryllium oxide on retention in JET ITER-like wall tiles
- Author
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JET Contributors, Makepeace, C., Pardanaud, C., Roubin, P., Borodkina, I., Ayres, C., Coad, P., Baron-Wiechec, A., Jepu, I., Heinola, K., Widdowson, A., Lozano-Perez, S., Abduallev, S., Abhangi, M., Abreu, P., Afzal, M., Aggarwal, K. M., Ahlgren, T., Ahn, J. H., Aho-Mantila, L., Aiba, N., Airila, M., Albanese, R., Aldred, V., Alegre, D., Alessi, E., Aleynikov, P., Alfier, A., Alkseev, A., Allinson, M., Alper, B., Alves, E., Ambrosino, G., Ambrosino, R., Amicucci, L., Amosov, V., Sunden, E. Andersson, Angelone, M., Anghel, M., Angioni, C., Appel, L., Appelbee, C., Arena, P., Ariola, M., Arnichand, H., Arshad, S., Ash, A., Ashikawa, N., Aslanyan, V., Asunta, O., Auriemma, F., Austin, Y., Avotina, L., Axton, M. D., Bacharis, M., Baciero, A., Baiao, D., Bailey, S., Baker, A., Balboa, I., Balden, M., Balshaw, N., Bament, R., Banks, J. W., Baranov, Y. F., Barnard, M. A., Barnes, D., Barnes, M., Barnsley, R., Wiechec, A. Baron, Orte, L. 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Departamento de Física Atómica, Molecular y Nuclear, Universidad de Sevilla. RNM138: Física Nuclear Aplicada, Department of Materials, University of Oxford [Oxford], Physique des interactions ioniques et moléculaires (PIIM), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), The National Research Nuclear University MEPhI (Moscow Engineering Physics Institute) [Moscow, Russia], Forschungszentrum Jülich GmbH | Centre de recherche de Juliers, Helmholtz-Gemeinschaft = Helmholtz Association, Culham Centre for Fusion Energy (CCFE), National Institute for Laser, Plasma and Radiation Physics (INFLPR), University of Helsinki, University of Oxford, Helsingin yliopisto = Helsingfors universitet = University of Helsinki, Department of Physics, and Materials Physics
- Subjects
Nuclear and High Energy Physics ,Technology and Engineering ,ADSORPTION ,Materials science ,Hydrogen ,oxidation ,Beryllium oxide ,Materials Science (miscellaneous) ,chemistry.chemical_element ,OXIDATION ,114 Physical sciences ,01 natural sciences ,o-2 ,010305 fluids & plasmas ,Fusion, plasma och rymdfysik ,chemistry.chemical_compound ,Adsorption ,0103 physical sciences ,H2O ,h2o ,ddc:530 ,Composite material ,010302 applied physics ,Jet (fluid) ,Physics ,[CHIM.MATE]Chemical Sciences/Material chemistry ,HYDROGEN ,Microstructure ,lcsh:TK9001-9401 ,Fusion, Plasma and Space Physics ,O-2 ,respiratory tract diseases ,Nuclear Energy and Engineering ,chemistry ,adsorption ,13. Climate action ,hydrogen ,lcsh:Nuclear engineering. Atomic power ,Beryllium - Abstract
Preliminary results investigating the microstructure, bonding and effect of beryllium oxide formation on retention in the JET ITER-like wall beryllium tiles, are presented. The tiles have been investigated by several techniques: Scanning Electron Microscopy (SEM) equipped with Energy Dispersive X-ray (EDX), Transmission Electron microscopy (TEM) equipped with EDX and Electron Energy Loss Spectroscopy (EELS), Raman Spectroscopy and Thermal Desorption Spectroscopy (TDS). This paper focuses on results from melted materials of the dump plate tiles in JET. From our results and the literature, it is concluded, beryllium can form micron deep oxide islands contrary to the nanometric oxides predicted under vacuum conditions. The deepest oxides analyzed were up to 2-micron thicknesses. The beryllium Deuteroxide (BeOxDy) bond was found with Raman Spectroscopy. Application of EELS confirmed the oxide presence and stoichiometry. Literature suggests these oxides form at temperatures greater than 700 degrees C where self-diffusion of beryllium ions through the surface oxide layer can occur. Further oxidation is made possible between oxygen plasma impurities and the beryllium ions now present at the wall surface. Under Ultra High Vacuum (UHV) nanometric Beryllium oxide layers are formed and passivate at room temperature. After continual cyclic heating (to the point of melt formation) in the presence of oxygen impurities from the plasma, oxide growth to the levels seen experimentally (approximately two microns) is proposed. This retention mechanism is not considered to contribute dramatically to overall retention in JET, due to low levels of melt formation. However, this mechanism, thought the result of operation environment and melt formation, could be of wider concern to ITER, dependent on wall temperatures. For complete list of authors see http://dx.doi.org/10.1016/j.nme.2019.02.022
- Published
- 2019
26. Investigation of deuterium trapping and release in the JET ITER-like wall divertor using TDS and TMAP
- Author
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JET Contributors, Likonen, J., Heinola, K., De Backer, A., Baron-Wiechec, A., Catarino, N., Jepu, I., Ayres, C. F., Goad, P., Koivuranta, S., Krat, S., Matthews, G. F., Mayer, M., Widdowson, A., Litaudon, X., Abduallev, S., Abhangi, M., Abreu, P., Afzal, M., Aggarwal, K. M., Ahlgren, T., Ahn, J. H., Aho-Mantila, L., Aiba, N., Airila, M., Albanese, R., Aldred, V., Alegre, D., Alessi, E., Aleynikov, P., Alfier, A., Alkseev, A., Allinson, M., Alper, B., Alves, E., Ambrosino, G., Ambrosino, R., Amicucci, L., Amosov, V., Sunden, E. Andersson, Angelone, M., Anghel, M., Angioni, C., Appel, L., Appelbee, C., Arena, P., Ariola, M., Arnichand, H., Arshad, S., Ash, A., Ashikawa, N., Aslanyan, V., Asunta, O., Auriemma, F., Austin, Y., Avotina, L., Axton, M. D., Ayres, C., Bacharis, M., Baciero, A., Baiao, D., Bailey, S., Baker, A., Balboa, I., Balden, M., Balshaw, N., Bament, R., Banks, J. W., Baranov, Y. F., Barnard, M. A., Barnes, D., Barnes, M., Barnsley, R., Wiechec, A. Baron, Orte, L. 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Departamento de Física Atómica, Molecular y Nuclear, Universidad de Sevilla. RNM138: Física Nuclear Aplicada, Doctoral Programme in Materials Research and Nanosciences, and Materials Physics
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retention ,Nuclear and High Energy Physics ,Technology and Engineering ,Materials science ,Fuel retention ,Materials Science (miscellaneous) ,Thermal desorption ,Trapping ,TILES ,Mass spectrometry ,114 Physical sciences ,01 natural sciences ,010305 fluids & plasmas ,Fusion, plasma och rymdfysik ,0103 physical sciences ,ddc:530 ,RETENTION ,tiles ,TDS ,010302 applied physics ,Jet (fluid) ,ta214 ,Physics ,Divertor ,lcsh:TK9001-9401 ,Fusion, Plasma and Space Physics ,Nuclear Energy and Engineering ,Deuterium ,JET ,lcsh:Nuclear engineering. Atomic power ,Atomic physics - Abstract
Selected set of samples from JET ITER-Like Wall (JET-ILW) divertor tiles exposed both in 2013-2014 and 2011-2014 has been analysed using Thermal Desorption Spectrometry (TDS). The deuterium (D) amounts obtained with TDS were compared with Ion Beam Analysis (IBA) and Secondary Ion Mass Spectrometry (SIMS) data. The highest amount of D was found on the top part of inner divertor which has regions with the thickest deposited layers. This area resides deep in the scrape-off layer. Changes in plasma configurations between the first (2011-2012) and the second (2013-2014) JET-ILW campaign altered the material migration towards the inner and the outer divertor corner increasing the amount of deposition in the shadowed areas of the divertor base tiles. D retention on the outer divertor tiles is clearly smaller than on the inner divertor tiles. Experimental TDS spectra for samples from the top part of inner divertor and from the outer strike point region were modelled using TMAP program. Experimental deuterium profiles obtained with SIMS have been used and the detrapping and the activation energies have been adjusted. Analysis of the results of the TMAP simulations enabled to determine the nature of traps in different samples. For complete list of authors see http://dx.doi.org/10.1016/j.nme.2019.02.031
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- 2019
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27. Exposure assessment
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Brown, M., primary
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28. The future of microbiological risk assessment
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Brown, M., primary and Stringer, M., additional
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29. Introduction
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Brown, M., primary and Campden, M. Stringer, additional
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30. Hazard identification
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Brown, M., primary
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31. Polygenic risk scores for prediction of breast cancer and breast cancer subtypes
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Mavaddat, N. (Nasim), Michailidou, K. (Kyriaki), Dennis, J. (Joe), Lush, M. (Michael), Fachal, L. (Laura), Lee, A. (Andrew), Tyrer, J. P. (Jonathan P.), Chen, T.-H. (Ting-Huei), Wang, Q. (Qin), Bolla, M. K. (Manjeet K.), Yang, X. (Xin), Adank, M. A. (Muriel A.), Ahearn, T. (Thomas), Aittomaki, K. (Kristiina), Allen, J. (Jamie), Andrulis, I. L. (Irene L.), Anton-Culver, H. (Hoda), Antonenkova, N. N. (Natalia N.), Arndt, V. (Volker), Aronson, K. J. (Kristan J.), Auer, P. L. (Paul L.), Auvinen, P. (Paivi), Barrdahl, M. (Myrto), Freeman, L. E. (Laura E. Beane), Beckmann, M. W. (Matthias W.), Behrens, S. (Sabine), Benitez, J. (Javier), Bermisheva, M. (Marina), Bernstein, L. (Leslie), Blomqvist, C. (Carl), Bogdanova, N. V. (Natalia, V), Bojesen, S. E. (Stig E.), Bonanni, B. (Bernardo), Borresen-Dale, A.-L. (Anne-Lise), Brauch, H. (Hiltrud), Bremer, M. (Michael), Brenner, H. (Hermann), Brentnall, A. (Adam), Brock, I. W. (Ian W.), Brooks-Wilson, A. (Angela), Brucker, S. Y. (Sara Y.), Bruening, T. (Thomas), Burwinkel, B. (Barbara), Campa, D. (Daniele), Carter, B. D. (Brian D.), Castelao, J. E. (Jose E.), Chanock, S. J. (Stephen J.), Chlebowski, R. (Rowan), Christiansen, H. (Hans), Clarke, C. L. (Christine L.), Collee, J. M. (J. Margriet), Cordina-Duverger, E. (Emilie), Cornelissen, S. (Sten), Couch, F. J. (Fergus J.), Cox, A. (Angela), Cross, S. S. (Simon S.), Czene, K. (Kamila), Daly, M. B. (Mary B.), Devilee, P. (Peter), Doerk, T. (Thilo), dos-Santos-Silva, I. (Isabel), Dumont, M. (Martine), Durcan, L. (Lorraine), Dwek, M. (Miriam), Eccles, D. M. (Diana M.), Ekici, A. B. (Arif B.), Eliassen, A. H. (A. Heather), Ellberg, C. (Carolina), Engel, C. (Christoph), Eriksson, M. (Mikael), Evans, D. G. (D. Gareth), Fasching, P. A. (Peter A.), Figueroa, J. (Jonine), Fletcher, O. (Olivia), Flyger, H. (Henrik), Foersti, A. (Asta), Fritschi, L. (Lin), Gabrielson, M. (Marike), Gago-Dominguez, M. (Manuela), Gapstur, S. M. (Susan M.), Garcia-Saenz, J. A. (Jose A.), Gaudet, M. M. (Mia M.), Georgoulias, V. (Vassilios), Giles, G. G. (Graham G.), Gilyazova, I. R. (Irina R.), Glendon, G. (Gord), Goldberg, M. S. (Mark S.), Goldgar, D. E. (David E.), Gonzalez-Neira, A. (Anna), Alnaes, G. I. (Grethe I. Grenaker), Grip, M. (Mervi), Gronwald, J. (Jacek), Grundy, A. (Anne), Guenel, P. (Pascal), Haeberle, L. (Lothar), Hahnen, E. (Eric), Haiman, C. A. (Christopher A.), Hakansson, N. (Niclas), Hamann, U. (Ute), Hankinson, S. E. (Susan E.), Harkness, E. F. (Elaine F.), Hart, S. N. (Steven N.), He, W. (Wei), Hein, A. (Alexander), Heyworth, J. (Jane), Hillemanns, P. (Peter), Hollestelle, A. (Antoinette), Hooning, M. J. (Maartje J.), Hoover, R. N. (Robert N.), Hopper, J. L. (John L.), Howell, A. (Anthony), Huang, G. (Guanmengqian), Humphreys, K. (Keith), Hunter, D. J. (David J.), Jakimovska, M. (Milena), Jakubowska, A. (Anna), Janni, W. (Wolfgang), John, E. M. (Esther M.), Johnson, N. (Nichola), Jones, M. E. (Michael E.), Jukkola-Vuorinen, A. (Arja), Jung, A. (Audrey), Kaaks, R. (Rudolf), Kaczmarek, K. (Katarzyna), Kataja, V. (Vesa), Keeman, R. (Renske), Kerin, M. J. (Michael J.), Khusnutdinova, E. (Elza), Kiiski, J. I. (Johanna, I), Knight, J. A. (Julia A.), Ko, Y.-D. (Yon-Dschun), Kosma, V.-M. (Veli-Matti), Koutros, S. (Stella), Kristensen, V. N. (Vessela N.), Kruger, U. (Ute), Kuehl, T. (Tabea), Lambrechts, D. (Diether), Le Marchand, L. (Loic), Lee, E. (Eunjung), Lejbkowicz, F. (Flavio), Lilyquist, J. (Jenna), Lindblom, A. (Annika), Lindstrom, S. (Sara), Lissowska, J. (Jolanta), Lo, W.-Y. (Wing-Yee), Loibl, S. (Sibylle), Long, J. (Jirong), Lubinski, J. (Jan), Lux, M. P. (Michael P.), MacInnis, R. J. (Robert J.), Maishman, T. (Tom), Makalic, E. (Enes), Kostovska, I. M. (Ivana Maleva), Mannermaa, A. (Arto), Manoukian, S. (Siranoush), Margolin, S. (Sara), Martens, J. W. (John W. M.), Martinez, M. E. (Maria Elena), Mavroudis, D. (Dimitrios), McLean, C. (Catriona), Meindl, A. (Alfons), Menon, U. (Usha), Middha, P. (Pooja), Miller, N. (Nicola), Moreno, F. (Fernando), Mulligan, A. M. (Anna Marie), Mulot, C. (Claire), Munoz-Garzon, V. M. (Victor M.), Neuhausen, S. L. (Susan L.), Nevanlinna, H. (Heli), Neven, P. (Patrick), Newman, W. G. (William G.), Nielsen, S. F. (Sune F.), Nordestgaard, B. G. (Borge G.), Norman, A. (Aaron), Offit, K. (Kenneth), Olson, J. E. (Janet E.), Olsson, H. (Hakan), Orr, N. (Nick), Pankratz, V. S. (V. Shane), Park-Simon, T.-W. (Tjoung-Won), Perez, J. I. (Jose I. A.), Perez-Barrios, C. (Clara), Peterlongo, P. (Paolo), Peto, J. (Julian), Pinchev, M. (Mila), Plaseska-Karanfilska, D. (Dijana), Polley, E. C. (Eric C.), Prentice, R. (Ross), Presneau, N. (Nadege), Prokofyeva, D. (Darya), Purrington, K. (Kristen), Pylkäs, K. (Katri), Rack, B. (Brigitte), Radice, P. (Paolo), Rau-Murthy, R. (Rohini), Rennert, G. (Gad), Rennert, H. S. (Hedy S.), Rhenius, V. (Valerie), Robson, M. (Mark), Romero, A. (Atocha), Ruddy, K. J. (Kathryn J.), Ruebner, M. (Matthias), Saloustros, E. (Emmanouil), Sandler, D. P. (Dale P.), Sawyer, E. J. (Elinor J.), Schmidt, D. F. (Daniel F.), Schmutzler, R. K. (Rita K.), Schneeweiss, A. (Andreas), Schoemaker, M. J. (Minouk J.), Schumacher, F. (Fredrick), Schuermann, P. (Peter), Schwentner, L. (Lukas), Scott, C. (Christopher), Scott, R. J. (Rodney J.), Seynaeve, C. (Caroline), Shah, M. (Mitul), Sherman, M. E. (Mark E.), Shrubsole, M. J. (Martha J.), Shu, X.-O. (Xiao-Ou), Slager, S. (Susan), Smeets, A. (Ann), Sohn, C. (Christof), Soucy, P. (Penny), Southey, M. C. (Melissa C.), Spinelli, J. J. (John J.), Stegmaier, C. (Christa), Stone, J. (Jennifer), Swerdlow, A. J. (Anthony J.), Tamimi, R. M. (Rulla M.), Tapper, W. J. (William J.), Taylor, J. A. (Jack A.), Terry, M. B. (Mary Beth), Thoene, K. (Kathrin), Tollenaar, R. A. (Rob A. E. M.), Tomlinson, I. (Ian), Truong, T. (Therese), Tzardi, M. (Maria), Ulmer, H.-U. (Hans-Ulrich), Untch, M. (Michael), Vachon, C. M. (Celine M.), van Veen, E. M. (Elke M.), Vijai, J. (Joseph), Weinberg, C. R. (Clarice R.), Wendt, C. (Camilla), Whittemore, A. S. (Alice S.), Wildiers, H. (Hans), Willett, W. (Walter), Winqvist, R. (Robert), Wolk, A. (Alicja), Yang, X. R. (Xiaohong R.), Yannoukakos, D. (Drakoulis), Zhang, Y. (Yan), Zheng, W. (Wei), Ziogas, A. (Argyrios), Clarke, C. (Christine), Balleine, R. (Rosemary), Baxter, R. (Robert), Braye, S. (Stephen), Carpenter, J. (Jane), Dahlstrom, J. (Jane), Forbes, J. (John), Lee, C. S. (C. Soon), Marsh, D. (Deborah), Morey, A. (Adrienne), Pathmanathan, N. (Nirmala), Scott, R. (Rodney), Simpson, P. (Peter), Spigelman, A. (Allan), Wilcken, N. (Nicholas), Yip, D. (Desmond), Zeps, N. (Nikolajs), Sexton, A. (Adrienne), Dobrovic, A. (Alex), Christian, A. (Alice), Trainer, A. (Alison), Fellows, A. (Andrew), Shelling, A. (Andrew), De Fazio, A. (Anna), Blackburn, A. (Anneke), Crook, A. (Ashley), Meiser, B. (Bettina), Patterson, B. (Briony), Clarke, C. (Christobel), Saunders, C. (Christobel), Hunt, C. (Clare), Scott, C. (Clare), Amor, D. (David), Ortega, D. G. (David Gallego), Marsh, D. (Deb), Edkins, E. (Edward), Salisbury, E. (Elizabeth), Haan, E. (Eric), Macrea, F. (Finlay), Farshid, G. (Gelareh), Lindeman, G. (Geoff), Trench, G. (Georgia), Mann, G. (Graham), Giles, G. (Graham), Gill, G. (Grantley), Thorne, H. (Heather), Campbell, I. (Ian), Hickie, I. (Ian), Caldon, L. (Liz), Winship, I. (Ingrid), Cui, J. (James), Flanagan, J. (James), Kollias, J. (James), Visvader, J. (Jane), Taylor, J. (Jessica), Burke, J. (Jo), Saunus, J. (Jodi), Forbs, J. (John), Hopper, J. (John), Beesley, J. (Jonathan), Kirk, J. (Judy), French, J. (Juliet), Tucker, K. (Kathy), Wu, K. (Kathy), Phillips, K. (Kelly), Forrest, L. (Laura), Lipton, L. (Lara), Andrews, L. (Leslie), Lobb, L. (Lizz), Walker, L. (Logan), Kentwell, M. (Maira), Spurdle, M. (Mandy), Cummings, M. (Margaret), Gleeson, M. (Margaret), Harris, M. (Marion), Jenkins, M. (Mark), Young, M. A. (Mary Anne), Delatycki, M. (Martin), Wallis, M. (Mathew), Burgess, M. (Matthew), Brown, M. (Melissa), Southey, M. (Melissa), Bogwitz, M. (Michael), Field, M. (Michael), Friedlander, M. (Michael), Gattas, M. (Michael), Saleh, M. (Mona), Aghmesheh, M. (Morteza), Hayward, N. (Nick), Pachter, N. (Nick), Cohen, P. (Paul), Duijf, P. (Pascal), James, P. (Paul), Simpson, P. (Pete), Fong, P. (Peter), Butow, P. (Phyllis), Williams, R. (Rachael), Kefford, R. (Rick), Simard, J. (Jacques), Balleine, R.-M. (Rose-Mary), Dawson, S.-J. (Sarah-Jane), Lok, S. (Sheau), O'connell, S. (Shona), Greening, S. (Sian), Nightingale, S. (Sophie), Edwards, S. (Stacey), Fox, S. (Stephen), McLachlan, S.-A. (Sue-Anne), Lakhani, S. (Sunil), Dudding, T. (Tracy), Antill, Y. (Yoland), Sahlberg, K. K. (Kristine K.), Ottestad, L. (Lars), Karesen, R. (Rolf), Schlichting, E. (Ellen), Holmen, M. M. (Marit Muri), Sauer, T. (Toril), Haakensen, V. (Vilde), Engebraten, O. (Olav), Naume, B. (Bjorn), Fossa, A. (Alexander), Kiserud, C. E. (Cecile E.), Reinertsen, K. V. (Kristin, V), Helland, A. (Aslaug), Riis, M. (Margit), Geisler, J. (Juergen), Dunning, A. M. (Alison M.), Thompson, D. J. (Deborah J.), Chenevix-Trench, G. (Georgia), Chang-Claude, J. (Jenny), Schmidt, M. K. (Marjanka K.), Hall, P. (Per), Milne, R. L. (Roger L.), Pharoah, P. D. (Paul D. P.), Antoniou, A. C. (Antonis C.), Chatterjee, N. (Nilanjan), Kraft, P. (Peter), Garcia-Closas, M. (Montserrat), Easton, D. F. (Douglas F.), Mavaddat, N. (Nasim), Michailidou, K. (Kyriaki), Dennis, J. (Joe), Lush, M. (Michael), Fachal, L. (Laura), Lee, A. (Andrew), Tyrer, J. P. (Jonathan P.), Chen, T.-H. (Ting-Huei), Wang, Q. (Qin), Bolla, M. K. (Manjeet K.), Yang, X. (Xin), Adank, M. A. (Muriel A.), Ahearn, T. (Thomas), Aittomaki, K. (Kristiina), Allen, J. (Jamie), Andrulis, I. L. (Irene L.), Anton-Culver, H. (Hoda), Antonenkova, N. N. (Natalia N.), Arndt, V. (Volker), Aronson, K. J. (Kristan J.), Auer, P. L. (Paul L.), Auvinen, P. (Paivi), Barrdahl, M. (Myrto), Freeman, L. E. (Laura E. Beane), Beckmann, M. W. (Matthias W.), Behrens, S. (Sabine), Benitez, J. (Javier), Bermisheva, M. (Marina), Bernstein, L. (Leslie), Blomqvist, C. (Carl), Bogdanova, N. V. (Natalia, V), Bojesen, S. E. (Stig E.), Bonanni, B. (Bernardo), Borresen-Dale, A.-L. (Anne-Lise), Brauch, H. (Hiltrud), Bremer, M. (Michael), Brenner, H. (Hermann), Brentnall, A. (Adam), Brock, I. W. (Ian W.), Brooks-Wilson, A. (Angela), Brucker, S. Y. (Sara Y.), Bruening, T. (Thomas), Burwinkel, B. (Barbara), Campa, D. (Daniele), Carter, B. D. (Brian D.), Castelao, J. E. (Jose E.), Chanock, S. J. (Stephen J.), Chlebowski, R. (Rowan), Christiansen, H. (Hans), Clarke, C. L. (Christine L.), Collee, J. M. (J. Margriet), Cordina-Duverger, E. (Emilie), Cornelissen, S. (Sten), Couch, F. J. (Fergus J.), Cox, A. (Angela), Cross, S. S. (Simon S.), Czene, K. (Kamila), Daly, M. B. (Mary B.), Devilee, P. (Peter), Doerk, T. (Thilo), dos-Santos-Silva, I. (Isabel), Dumont, M. (Martine), Durcan, L. (Lorraine), Dwek, M. (Miriam), Eccles, D. M. (Diana M.), Ekici, A. B. (Arif B.), Eliassen, A. H. (A. Heather), Ellberg, C. (Carolina), Engel, C. (Christoph), Eriksson, M. (Mikael), Evans, D. G. (D. Gareth), Fasching, P. A. (Peter A.), Figueroa, J. (Jonine), Fletcher, O. (Olivia), Flyger, H. (Henrik), Foersti, A. (Asta), Fritschi, L. (Lin), Gabrielson, M. (Marike), Gago-Dominguez, M. (Manuela), Gapstur, S. M. (Susan M.), Garcia-Saenz, J. A. (Jose A.), Gaudet, M. M. (Mia M.), Georgoulias, V. (Vassilios), Giles, G. G. (Graham G.), Gilyazova, I. R. (Irina R.), Glendon, G. (Gord), Goldberg, M. S. (Mark S.), Goldgar, D. E. (David E.), Gonzalez-Neira, A. (Anna), Alnaes, G. I. (Grethe I. Grenaker), Grip, M. (Mervi), Gronwald, J. (Jacek), Grundy, A. (Anne), Guenel, P. (Pascal), Haeberle, L. (Lothar), Hahnen, E. (Eric), Haiman, C. A. (Christopher A.), Hakansson, N. (Niclas), Hamann, U. (Ute), Hankinson, S. E. (Susan E.), Harkness, E. F. (Elaine F.), Hart, S. N. (Steven N.), He, W. (Wei), Hein, A. (Alexander), Heyworth, J. (Jane), Hillemanns, P. (Peter), Hollestelle, A. (Antoinette), Hooning, M. J. (Maartje J.), Hoover, R. N. (Robert N.), Hopper, J. L. (John L.), Howell, A. (Anthony), Huang, G. (Guanmengqian), Humphreys, K. (Keith), Hunter, D. J. (David J.), Jakimovska, M. (Milena), Jakubowska, A. (Anna), Janni, W. (Wolfgang), John, E. M. (Esther M.), Johnson, N. (Nichola), Jones, M. E. (Michael E.), Jukkola-Vuorinen, A. (Arja), Jung, A. (Audrey), Kaaks, R. (Rudolf), Kaczmarek, K. (Katarzyna), Kataja, V. (Vesa), Keeman, R. (Renske), Kerin, M. J. (Michael J.), Khusnutdinova, E. (Elza), Kiiski, J. I. (Johanna, I), Knight, J. A. (Julia A.), Ko, Y.-D. (Yon-Dschun), Kosma, V.-M. (Veli-Matti), Koutros, S. (Stella), Kristensen, V. N. (Vessela N.), Kruger, U. (Ute), Kuehl, T. (Tabea), Lambrechts, D. (Diether), Le Marchand, L. (Loic), Lee, E. (Eunjung), Lejbkowicz, F. (Flavio), Lilyquist, J. (Jenna), Lindblom, A. (Annika), Lindstrom, S. (Sara), Lissowska, J. (Jolanta), Lo, W.-Y. (Wing-Yee), Loibl, S. (Sibylle), Long, J. (Jirong), Lubinski, J. (Jan), Lux, M. P. (Michael P.), MacInnis, R. J. (Robert J.), Maishman, T. (Tom), Makalic, E. (Enes), Kostovska, I. M. (Ivana Maleva), Mannermaa, A. (Arto), Manoukian, S. (Siranoush), Margolin, S. (Sara), Martens, J. W. (John W. M.), Martinez, M. E. (Maria Elena), Mavroudis, D. (Dimitrios), McLean, C. (Catriona), Meindl, A. (Alfons), Menon, U. (Usha), Middha, P. (Pooja), Miller, N. (Nicola), Moreno, F. (Fernando), Mulligan, A. M. (Anna Marie), Mulot, C. (Claire), Munoz-Garzon, V. M. (Victor M.), Neuhausen, S. L. (Susan L.), Nevanlinna, H. (Heli), Neven, P. (Patrick), Newman, W. G. (William G.), Nielsen, S. F. (Sune F.), Nordestgaard, B. G. (Borge G.), Norman, A. (Aaron), Offit, K. (Kenneth), Olson, J. E. (Janet E.), Olsson, H. (Hakan), Orr, N. (Nick), Pankratz, V. S. (V. Shane), Park-Simon, T.-W. (Tjoung-Won), Perez, J. I. (Jose I. A.), Perez-Barrios, C. (Clara), Peterlongo, P. (Paolo), Peto, J. (Julian), Pinchev, M. (Mila), Plaseska-Karanfilska, D. (Dijana), Polley, E. C. (Eric C.), Prentice, R. (Ross), Presneau, N. (Nadege), Prokofyeva, D. (Darya), Purrington, K. (Kristen), Pylkäs, K. (Katri), Rack, B. (Brigitte), Radice, P. (Paolo), Rau-Murthy, R. (Rohini), Rennert, G. (Gad), Rennert, H. S. (Hedy S.), Rhenius, V. (Valerie), Robson, M. (Mark), Romero, A. (Atocha), Ruddy, K. J. (Kathryn J.), Ruebner, M. (Matthias), Saloustros, E. (Emmanouil), Sandler, D. P. (Dale P.), Sawyer, E. J. (Elinor J.), Schmidt, D. F. (Daniel F.), Schmutzler, R. K. (Rita K.), Schneeweiss, A. (Andreas), Schoemaker, M. J. (Minouk J.), Schumacher, F. (Fredrick), Schuermann, P. (Peter), Schwentner, L. (Lukas), Scott, C. (Christopher), Scott, R. J. (Rodney J.), Seynaeve, C. (Caroline), Shah, M. (Mitul), Sherman, M. E. (Mark E.), Shrubsole, M. J. (Martha J.), Shu, X.-O. (Xiao-Ou), Slager, S. (Susan), Smeets, A. (Ann), Sohn, C. (Christof), Soucy, P. (Penny), Southey, M. C. (Melissa C.), Spinelli, J. J. (John J.), Stegmaier, C. (Christa), Stone, J. (Jennifer), Swerdlow, A. J. (Anthony J.), Tamimi, R. M. (Rulla M.), Tapper, W. J. (William J.), Taylor, J. A. (Jack A.), Terry, M. B. (Mary Beth), Thoene, K. (Kathrin), Tollenaar, R. A. (Rob A. E. M.), Tomlinson, I. (Ian), Truong, T. (Therese), Tzardi, M. (Maria), Ulmer, H.-U. (Hans-Ulrich), Untch, M. (Michael), Vachon, C. M. (Celine M.), van Veen, E. M. (Elke M.), Vijai, J. (Joseph), Weinberg, C. R. (Clarice R.), Wendt, C. (Camilla), Whittemore, A. S. (Alice S.), Wildiers, H. (Hans), Willett, W. (Walter), Winqvist, R. (Robert), Wolk, A. (Alicja), Yang, X. R. (Xiaohong R.), Yannoukakos, D. (Drakoulis), Zhang, Y. (Yan), Zheng, W. (Wei), Ziogas, A. (Argyrios), Clarke, C. (Christine), Balleine, R. (Rosemary), Baxter, R. (Robert), Braye, S. (Stephen), Carpenter, J. (Jane), Dahlstrom, J. (Jane), Forbes, J. (John), Lee, C. S. (C. Soon), Marsh, D. (Deborah), Morey, A. (Adrienne), Pathmanathan, N. (Nirmala), Scott, R. (Rodney), Simpson, P. (Peter), Spigelman, A. (Allan), Wilcken, N. (Nicholas), Yip, D. (Desmond), Zeps, N. (Nikolajs), Sexton, A. (Adrienne), Dobrovic, A. (Alex), Christian, A. (Alice), Trainer, A. (Alison), Fellows, A. (Andrew), Shelling, A. (Andrew), De Fazio, A. (Anna), Blackburn, A. (Anneke), Crook, A. (Ashley), Meiser, B. (Bettina), Patterson, B. (Briony), Clarke, C. (Christobel), Saunders, C. (Christobel), Hunt, C. (Clare), Scott, C. (Clare), Amor, D. (David), Ortega, D. G. (David Gallego), Marsh, D. (Deb), Edkins, E. (Edward), Salisbury, E. (Elizabeth), Haan, E. (Eric), Macrea, F. (Finlay), Farshid, G. (Gelareh), Lindeman, G. (Geoff), Trench, G. (Georgia), Mann, G. (Graham), Giles, G. (Graham), Gill, G. (Grantley), Thorne, H. (Heather), Campbell, I. (Ian), Hickie, I. (Ian), Caldon, L. (Liz), Winship, I. (Ingrid), Cui, J. (James), Flanagan, J. (James), Kollias, J. (James), Visvader, J. (Jane), Taylor, J. (Jessica), Burke, J. (Jo), Saunus, J. (Jodi), Forbs, J. (John), Hopper, J. (John), Beesley, J. (Jonathan), Kirk, J. (Judy), French, J. (Juliet), Tucker, K. (Kathy), Wu, K. (Kathy), Phillips, K. (Kelly), Forrest, L. (Laura), Lipton, L. (Lara), Andrews, L. (Leslie), Lobb, L. (Lizz), Walker, L. (Logan), Kentwell, M. (Maira), Spurdle, M. (Mandy), Cummings, M. (Margaret), Gleeson, M. (Margaret), Harris, M. (Marion), Jenkins, M. (Mark), Young, M. A. (Mary Anne), Delatycki, M. (Martin), Wallis, M. (Mathew), Burgess, M. (Matthew), Brown, M. (Melissa), Southey, M. (Melissa), Bogwitz, M. (Michael), Field, M. (Michael), Friedlander, M. (Michael), Gattas, M. (Michael), Saleh, M. (Mona), Aghmesheh, M. (Morteza), Hayward, N. (Nick), Pachter, N. (Nick), Cohen, P. (Paul), Duijf, P. (Pascal), James, P. (Paul), Simpson, P. (Pete), Fong, P. (Peter), Butow, P. (Phyllis), Williams, R. (Rachael), Kefford, R. (Rick), Simard, J. (Jacques), Balleine, R.-M. (Rose-Mary), Dawson, S.-J. (Sarah-Jane), Lok, S. (Sheau), O'connell, S. (Shona), Greening, S. (Sian), Nightingale, S. (Sophie), Edwards, S. (Stacey), Fox, S. (Stephen), McLachlan, S.-A. (Sue-Anne), Lakhani, S. (Sunil), Dudding, T. (Tracy), Antill, Y. (Yoland), Sahlberg, K. K. (Kristine K.), Ottestad, L. (Lars), Karesen, R. (Rolf), Schlichting, E. (Ellen), Holmen, M. M. (Marit Muri), Sauer, T. (Toril), Haakensen, V. (Vilde), Engebraten, O. (Olav), Naume, B. (Bjorn), Fossa, A. (Alexander), Kiserud, C. E. (Cecile E.), Reinertsen, K. V. (Kristin, V), Helland, A. (Aslaug), Riis, M. (Margit), Geisler, J. (Juergen), Dunning, A. M. (Alison M.), Thompson, D. J. (Deborah J.), Chenevix-Trench, G. (Georgia), Chang-Claude, J. (Jenny), Schmidt, M. K. (Marjanka K.), Hall, P. (Per), Milne, R. L. (Roger L.), Pharoah, P. D. (Paul D. P.), Antoniou, A. C. (Antonis C.), Chatterjee, N. (Nilanjan), Kraft, P. (Peter), Garcia-Closas, M. (Montserrat), and Easton, D. F. (Douglas F.)
- Abstract
Stratification of women according to their risk of breast cancer based on polygenic risk scores (PRSs) could improve screening and prevention strategies. Our aim was to develop PRSs, optimized for prediction of estrogen receptor (ER)-specific disease, from the largest available genome-wide association dataset and to empirically validate the PRSs in prospective studies. The development dataset comprised 94,075 case subjects and 75,017 control subjects of European ancestry from 69 studies, divided into training and validation sets. Samples were genotyped using genome-wide arrays, and single-nucleotide polymorphisms (SNPs) were selected by stepwise regression or lasso penalized regression. The best performing PRSs were validated in an independent test set comprising 11,428 case subjects and 18,323 control subjects from 10 prospective studies and 190,040 women from UK Biobank (3,215 incident breast cancers). For the best PRSs (313 SNPs), the odds ratio for overall disease per 1 standard deviation in ten prospective studies was 1.61 (95%CI: 1.57–1.65) with area under receiver-operator curve (AUC) = 0.630 (95%CI: 0.628–0.651). The lifetime risk of overall breast cancer in the top centile of the PRSs was 32.6%. Compared with women in the middle quintile, those in the highest 1% of risk had 4.37- and 2.78-fold risks, and those in the lowest 1% of risk had 0.16- and 0.27-fold risks, of developing ER-positive and ER-negative disease, respectively. Goodness-of-fit tests indicated that this PRS was well calibrated and predicts disease risk accurately in the tails of the distribution. This PRS is a powerful and reliable predictor of breast cancer risk that may improve breast cancer prevention programs.
- Published
- 2019
32. Overview of the JET ITER-like wall divertor
- Author
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Widdowson, A., Alves, E., Baron-Wiechec, A., Barradas, N. P., Catarino, N., Coad, J. P., Corregidor, V., Garcia-Carrasco, A., Heinola, K., Koivuranta, S., Krat, S., Lahtinen, A., Likonen, J., Mayer, M., Petersson, P., Rubel, M., Van Boxel, S., Abhangi, M., Abreu, P., Aftanas, M., Afzal, M., Aggarwal, K. M., Aho-Mantila, L., Ahonen, E., Aints, M., Airila, M., Albanese, R., Alegre, D., Alessi, E., Aleynikov, P., Alfier, A., Alkseev, A., Allan, P., Almaviva, S., Alonso, A., Alper, B., Alsworth, I., Alves, D., Ambrosino, G., Ambrosino, R., Amosov, V., Andersson, F., Andersson Sunden, E., Angelone, M., Anghel, A., Anghel, M., Angioni, C., Appel, L., Apruzzese, G., Arena, P., Ariola, M., Arnich, Arnoux, G., Arshad, S., Ash, A., Asp, E., Asunta, O., Atanasiu, C. V., Austin, Y., Avotina, L., Axton, M. D., Ayres, C., Bachmann, C., Baciero, A., Baiao, D., Bailescu, V., Baiocchi, B., Baker, A., Baker, R. A., Balboa, I., Balden, M., Balshaw, N., Bament, R., Banks, J. W., Baranov, Y. F., Barlow, I. L., Barnard, M. A., Barnes, D., Barnsley, R., Baron Wiechec, A., Baruzzo, M., Basiuk, V., Bassan, M., Bastow, R., Batista, A., Batistoni, P., Bauer, R., Bauvir, B., Bazylev, B., Beal, J., Beaumont, P. S., Becoulet, A., Bednarczyk, P., Bekris, N., Beldishevski, M., Bell, K., Belli, F., Bellinger, M., Belo, J. K., Belo, P., Belonohy, E., Benterman, N. A., Bergsaker, H., Bernardo, J., Bernert, M., Berry, M., Bertalot, L., Beurskens, M. N. A., Bieg, B., Bielecki, J., Biewer, T., Bigi, M., Bilkova, P., Binda, F., Bizarro, J. P. S., Bjorkas, C., Blackman, K., Blackman, T. R., Blanchard, P., Blanco, E., Blatchford, P., Bobkov, V., Boboc, A., Bodnar, G., Bogar, O., Bolzonella, T., Boncagni, L., Bonham, R., Bonheure, G., Boom, J., Booth, J., Borba, D., Borodin, D., Botrugno, A., Boulbe, C., Boulting, P., Bovert, K. V., Bowden, M., Bower, C., Boyce, T., Boyer, H. J., Bradshaw, J. M. A., Braic, V., Breizman, B., Bremond, S., Brennan, P. D., Brett, A., Brezinsek, S., Bright, M. D. J., Brix, M., Broeckx, W., Brombin, M., Brown, B. C., Brown, D. P. D., Brown, M., Bruno, E., Bucalossi, J., Buch, J., Buckley, M. A., Bucko, K., Budny, R., Buffer, Bulman, M., Bulmer, N., Bunting, P., Buratti, P., Burcea, G., Burckhart, A., Buscarino, A., Butcher, P. R., Butler, N. K., Bykov, I., Byrne, J., Byszuk, A., Cackett, A., Cahyna, P., Cain, G., Calabro, G., Callaghan, C. P., Campling, D. C., Cane, J., Cannas, B., Capel, A. J., Caputano, M., Card, P. J., Cardinali, A., Carman, P., Carralero, D., Carraro, L., Carvalho, B. B., Carvalho, I., Carvalho, P., Casson, F. J., Castaldo, C., Cavazzana, R., Cavinato, M., Cazzaniga, A., Cecconello, M., Cecil, E., Cenedese, A., Centioli, C., Cesario, R., Challis, C. D., ler, M., ra, D., Chang, C. S., Chankin, A., Chapman, I. T., Chapman, S. C., Chernyshova, M., Chiru, P., Chitarin, G., Chouli, B., Chung, N., Ciraolo, G., Ciric, D., Citrin, J., Clairet, F., Clark, E., Clatworthy, D., Clay, R., Clever, M., Coates, P. A., Coccorese, V., Cocilovo, V., Coda, S., Coelho, R., Coenen, J. W., Coffey, I., Colas, L., Collins, S., Conboy, J. E., Conroy, S., Cook, N., Coombs, D., Cooper, D., Cooper, S. R., Corre, Y., Corrigan, G., Cortes, S., Coster, D., Couchman, A. S., Cox, M., Cox, M. P., Cox, P., Craciunescu, T., Cramp, S., Crisanti, F., Cristescu, I., Croci, G., Croft, O., Crombe, K., Crowe, R., Cruz, N., Cseh, G., Cull, K., Cupido, L., Curran, D., Curuia, M., Czarnecka, A., Czarski, T., Dalley, S., Dalziel, A., Darrow, D., Davies, R., Davis, W., Day, C., Day, I. E., de la Cal, E., de la Luna, E., De Magistris, M., de Pablos, J. L., De Tommasi, G., de Vries, P. C., Deakin, K., Deane, J., Decker, J., Degli Agostini, F., Dejarnac, R., Delabie, E., den Harder, N., Dendy, R. O., Denner, P., Devaux, S., Devynck, P., Di Maio, F., Di Pace, L., Dittmar, T., Dodt, D., Donne, T., Dooley, P., Dorling, S. E., Dormido-Canto, S., Doswon, S., Douai, D., Doyle, P. T., Dreischuh, T., Drewelow, P., Drozdov, V., Drozdowicz, K., Dumont, R., Dumortier, P., Dunai, D., Dunne, M., Duran, I., Durodie, F., Dutta, P., Duval, B., Dux, R., Dylst, K., Dzysiuk, N., Edappala, P. V., Edwards, A. M., Eich, Th., Ekedahl, A., Elevant, T., El-Jorf, R., Elsmore, C. G., Ericsson, G., Eriksson, A., Eriksson, J., Eriksson, L. G., Esposito, B., Esser, H. G., Esteve, D., Evans, G. E., Evans, J., Ewart, G. D., Ewers, D. T., Fagan, D., Falie, D., Farthing, J. W., Fasoli, A., Fattorini, L., Faugeras, B., Faustin, J., Fawlk, N., Federici, G., Fedorczak, N., Felton, R. C., Fenzi, C., Fernades, A., Fern, es, H., Ferreira, J., Fessey, J. A., Figini, L., Figueiredo, A., Figueiredo, J., Fil, A., Finburg, P., Firdaouss, M., Fischer, U., Fittill, L., Fitzgerald, M., Flammini, D., Flanagan, J., Fleming, C., Flinders, K., Formisano, A., Forsythe, L., Fortuna, L., Fortune, M., Frasca, M., Frassinetti, L., Freisinger, M., Fresa, R., Frigione, D., Fuchs, V., Fyvie, J., Gadomska, M., Gal, K., Galperti, C., Galvao, R., Gao, X., Garavaglia, S., Garcia, J., Garcia-Munoz, M., Gardner, M., Garzotti, L., Gaudio, P., Gauthier, E., Gaze, J. W., Gear, D. F., Gee, S. J., Gelfusa, M., Genangeli, E., Gerasimov, S., Gervasini, G., Ghate, M., Gherendi, M., Giacalone, J. C., Giacomelli, L., Gibson, C. S., Giegerich, T., Gin, D., Giovannozzi, E., Girardo, J. B., Giroud, C., Giruzzi, G., Gleason-Gonzalez, C., Godwin, J., Gohil, P., Gojska, A., Goloborod'ko, V., Gomes, R., Goncalves, B., Goniche, M., Gonzalez, S., Goodsell, B., Goodyear, A., Gorini, G., Goussarov, A., Graham, B., Graham, M. E., Graves, J., Grazier, N., Green, N. R., Greuner, H., Grigore, E., Griph, F. S., Grisolia, C., Grist, D., Groth, M., Grundy, C. N., Gryaznevich, M., Guard, D., Gubb, D., Guillemaut, C., Guo, Y., Utoh, H. H., Hackett, L. J., Hacquin, S., Hagar, A., Hakola, A., Halitovs, M., Hall, S. J., Hallworth Cook, S. P., Hammond, K., Hart, J., Harting, D., Hartmann, N., Haupt, T. D. V., Hawkes, N. C., Hawkins, J., Haydon, P. W., Hazel, S., Heesterman, P. J. L., Hellesen, C., Hellsten, T., Helou, W., Hemming, O. N., Hender, T. C., Henderson, M., Henriques, R., Hepple, D., Hermon, G., Hidalgo, C., Highcock, E. G., Hill, J. W., Hill, M., Hillairet, J., Hillesheim, J., Hillis, D., Hjalmarsson, A., Hobirk, J., Hogben, C. H. A., Hogeweij, G. M. D., Homfray, D. A., Horacek, J., Horton, A. R., Horton, L. D., Hotchin, S. P., Hough, M. R., Howarth, P. J., Huber, A., Huddleston, T. M., Hughes, M., Hunter, C. L., Hurzlmeier, H., Huygen, S., Huynh, P., Igitkhanov, J., Iglesias, D., Imrisek, M., Ivanova, D., Ivanova-Stanik, I., Ivings, E., Jachmich, S., Jacobsen, A. S., Jacquet, P., Jakubowska, K., James, J., Janky, F., Jarvinen, A., Jaulmes, F., Jednorog, S., Jenkins, C., Jenkins, I., Jesko, K., Joffrin, E., Johnson, R., Johnson, T., Joita, L., Jones, G., Jones, T. T. C., Joyce, L., Jupen, C., Hoshino, K. K., Kallenbach, A., Kalupin, D., Kamiya, K., Kaniewski, J., Kantor, A., Karhunen, J., Kasprowicz, G., Kaveney, G., Kazakov, Y., Keeling, D. L., Keep, J., Kempenaars, M., Kennedy, C., Kenny, D., Khilkevich, E., Kiisk, M., Kim, H. -T., Kim, H. S., King, C., King, D., King, R. F., Kinna, D. J., Kiptily, V., Kirov, K., Kirschner, A., Kizane, G., Klepper, C., Knaup, M., Knipe, S. J., Kobuchi, T., Kochl, F., Kocsis, G., Kogut, D., Koppen, M., Koskela, T., Koslowski, H. R., Kotov, V., Kowalska-Strzeciwilk, E., Krasilnikov, A., Krasilnikov, V., Kreter, A., Krieger, K., Krivchenkov, Y., Krivska, A., Kruezi, U., Ksiazek, I., Kukushkin, A., Kundu, A., Kurki-Suonio, T., Kwon, O. T., Kyrytsya, V., Laan, M., Labate, C., Laguardia, L., Lam, N., Lane, C., Lang, P. T., Lapins, J., Lasa, A., Last, J. R., Lawson, A., Lawson, K. D., Lazaros, A., Lazzaro, E., Lee, S., Leggate, H. J., Lehnen, M., Leichtle, D., Leichuer, P., Leipold, F., Lengar, I., Lennholm, M., Lerche, E., Leyl, Leysen, W., Liang, Y., Lindholm, V., Linke, J., Linsmeier, Ch., Lipschultz, B., Litaudon, X., Liu, G., Liu, Y., Lo Schiavo, V. P., Loarer, T., Loarte, A., Lobel, R. C., Lohr, N., Lomas, P. J., Lonnroth, J., Lopez, J., Lopez, J. M., Louche, F., Loving, A. B., Lowbridge, S., Lowry, C., Luce, T., Lucock, R. M. A., Lukin, A., Lungu, A. M., Lungu, C. P., Lupelli, I., Lyssoivan, A., Macheta, P., Mackenzie, A. S., Maddaluno, G., Maddison, G. P., Magesh, B., Maget, P., Maggi, C. F., Maier, H., Mailloux, J., Maj, A., Makkonen, T., Makwana, R., Malaquias, A., Mansffield, F., Mansfield, M., Manso, M. E., Mantica, P., Mantsinen, M., Manzanares, A., Mar, et, Y., Marcenko, N., Marchetto, C., Marchuk, O., Marinelli, M., Marinucci, M., Markovic, T., Marocco, D., Marot, L., Marren, C. A., Marsen, S., Marshal, R., Martin, A., Martin, D. L., Martin, Y., Martin de Aguilera, A., Martin-Solis, J. R., Masiello, A., Maslov, M., Maslova, V., Matejcik, S., Mattei, M., Matthews, G. F., Matveev, D., Matveev, M., Maviglia, F., Mayoral, M. -L., Mazon, D., Mazzotta, C., McAdams, R., McCarthy, P. J., McClements, K. G., McCormick, K., McCullen, P. A., McDonald, D., Mcgregor, R., McKean, R., McKehon, J., McKinley, R., Meadows, I., Meadows, R. C., Medina, F., Medl, Medley, S., Meigh, S., Meigs, A. G., Meneses, L., Menmuir, S., Merrigan, I. R., Mertens, Ph., Meshchaninov, S., Messiaen, A., Meszaros, B., Meyer, H., Miano, G., Michling, R., Middleton-Gear, D., Miettunen, J., Migliucci, P., Militello-Asp, E., Minucci, S., Mirizzi, F., Miyoshi, Y., Mlynar, J., Monakhov, I., Monier-Garbet, P., Mooney, R., Moradi, S., Mordijck, S., Moreira, L., Moreno, R., Morgan, P. D., Morgan, R., Morley, L., Morlock, C., Morris, A. W., Morris, J., Moser, L., Moulton, D., Murari, A., Muraro, A., Mustata, I., Asakura, N. N., Nabais, F., Nakano, T., Nardon, E., Naulin, V., Nave, M. F. F., Nedzelski, I., Neethiraj, N., Nemtsev, G., Nespoli, F., Neto, A., Neu, R., Neubauer, O., Newman, M., Nicholls, K. J., Nicolai, D., Nicolas, T., Nieckchen, P., Nielsen, P., Nightingale, M. P. S., Nilsson, E., Nishijima, D., Noble, C., Nocente, M., Nodwell, D., Nordman, H., Nunes, I., O'Meara, B., Oberkofler, M., Obryk, B., Odupitan, T., Ogawa, M. T., O'Gorman, T., Okabayashi, M., Olariu, S., O'Mullane, M., Ongena, J., Orsitto, F., Oswuigwe, B. I., Pace, N., Pacella, D., Page, A., Paget, A., Pagett, D., Pajuste, E., Palazzo, S., Pamela, J., Pamela, S., Panin, A., Panja, S., Papp, P., Parail, V., Paris, P., Parish, S. C. W., Park, M., Parsloe, A., Pasqualotto, R., Pearson, I. J., Pedrosa, M. A., Pereira, R., Perelli Cippo, E., Perez von Thun, Ch., Perez-Von-Thun, C., Pericoli-Ridolfini, V., Perona, A., Peruzzo, S., Peschanyi, S., Peterka, M., Petravich, G., Petrzilka, V., Pfefferle, D., Philipps, V., Pietropaolo, A., Pillon, M., Pintsuk, G., Piovesan, P., Pires dos Reis, A., Pironti, A., Pisano, F., Pitts, R., Plusczyk, C., Plyusnin, V., Pomaro, N., Pompilian, O., Pool, P. J., Popovichev, S., Porcelli, F., Porosnicu, C., Porton, M., Pospieszczyk, A., Possnert, G., Potzel, S., Powell, T., Pozniak, K., Pozzi, J., Prajapati, V., Prakash, R., Prestopino, G., Price, D., Price, R., Prior, P., Prokopowicz, R., Proudfoot, R., Puglia, P., Puiatti, M. E., Pulley, D., Purahoo, K., Putterich, T., Quercia, A., Rachlew, E., Rack, M., Raeder, J., Rainford, M. S. J., Ramogida, G., Ranjan, S., Rasmussen, J., Rasmussen, J. J., Rathod, K., Ratta, G., Rayner, C., Rebai, M., Reece, D., Reed, A., Refy, D., Regan, B., Regana, J., Reich, M., Reid, P., Reinelt, M., Reinke, M. L., Reinke, M., Reiser, D., Reiter, D., Rendell, D., Reux, C., Riccardo, V., Rimini, F. G., Riva, M., Roberts, J. E. C., Robins, R. J., Robinson, S. A., Robinson, T., Robson, D. W., Roddick, P., Rodionov, R., Rohde, V., Romanelli, F., Romanelli, M., Romanelli, S., Romano, A., Rowe, D., Rowe, S., Rowley, A., Rubinacci, G., Ruchko, L., Ruiz, M., Ruset, C., Ryc, L., Rzadkiewicz, J., Saarelma, S., Sabot, R., Sadakov, S., Safi, E., Sagar, P., Saibene, G., Saint-Laurent, F., Salewski, M., Salmi, A., Salzedas, F., Samm, U., S, iford, D., quist, P., Santa, P., Santala, M. I. K., Sartori, F., Sartori, R., Saunders, R., Sauter, O., Scannell, R., Scarabosio, A., Schlummer, T., Schmidt, V., Schmitz, O., Schmuck, S., Schneider, M., Scholz, M., Schopf, K., Schweer, B., Sergienko, G., Serikov, A., Sertoli, M., Shabbir, A., Shannon, M., Shannon, M. M. J., Sharapov, S. E., Shaw, I., Shaw, S. R., Shepherd, A., Shevelev, A., Shumack, A., Sibbald, M., Sieglin, B., Silva, C., Simmons, P. A., Sinha, A., Sipila, S. K., Sips, A. C. C., Siren, P., Sirinelli, A., Sjostr, Skiba, M., Skilton, R., Slade, B., Smith, N., Smith, P. G., Smith, T. J., Snoj, L., Soare, S., Solano, E. R., Soldatov, S., Sonato, P., Sopplesa, A., Sousa, J., Sowden, C. B. C., Sozzi, C., Sparkes, A., Spelzini, T., Spineanu, F., Stables, G., Stamatelatos, I., Stamp, M. F., Stancalie, V., Stankiewicz, R., Stankunas, G., Stano, M., Stan-Sion, C., Starkey, D. E., Stead, M. J., Stejner, M., Stephen, A. V., Stephen, M., Stevens, B. 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P., Valcarcel, D., Valisa, M., Valovic, M., Van Eester, D., Van Renterghem, W., van Rooij, G. J., Var, as, C. A. F., Varoutis, S., Vartanian, S., Vasava, K., Vdovin, V., Vega, J., Verdoolaege, G., Verhoeven, R., Verona, C., Vervier, M., Veshchev, E., Vezinet, D., Vicente, J., Villari, S., Villone, F., Vinyar, I., Viola, B., Vitelli, R., Vitins, A., Vlad, M., Voitsekhovitch, I., Vondracek, P., Vrancken, M., Pires de Sa, W. W., Waldon, C. W. F., Walker, M., Walsh, M., Warren, R. J., Waterhouse, J., Watkins, N. W., Watts, C., Wauters, T., Way, M. W., Webster, A., Weckmann, A., Weil, Weisen, H., Weiszflog, M., Welte, S., Wendel, J., Wenninger, R., West, A. T., Wheatley, M. R., Whetham, S., Whitehead, A. M., Whitehead, B. D., Whittington, P., Widdowson, A. M., Wiesen, S., Wilkes, D., Wilkinson, J., Williams, M., Wilson, A. R., Wilson, D. J., Wilson, H. R., Wischmeier, M., Withenshaw, G., Witts, D. 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P., Valcarcel, D., Valisa, M., Valovic, M., Van Eester, D., Van Renterghem, W., van Rooij, G. J., Var, As, C. A. F., Varoutis, S., Vartanian, S., Vasava, K., Vdovin, V., Vega, J., Verdoolaege, G., Verhoeven, R., Verona, C., Vervier, M., Veshchev, E., Vezinet, D., Vicente, J., Villari, S., Villone, F., Vinyar, I., Viola, B., Vitelli, R., Vitins, A., Vlad, M., Voitsekhovitch, I., Vondracek, P., Vrancken, M., Pires de Sa, W. W., Waldon, C. W. F., Walker, M., Walsh, M., Warren, R. J., Waterhouse, J., Watkins, N. W., Watts, C., Wauters, T., Way, M. W., Webster, A., Weckmann, A., Weil, Weisen, H., Weiszflog, M., Welte, S., Wendel, J., Wenninger, R., West, A. T., Wheatley, M. R., Whetham, S., Whitehead, A. M., Whitehead, B. D., Whittington, P., Widdowson, A. M., Wiesen, S., Wilkes, D., Wilkinson, J., Williams, M., Wilson, A. R., Wilson, D. J., Wilson, H. R., Wischmeier, M., Withenshaw, G., Witts, D. M., Wojciech, D., Wojenski, A., Wood, D., Wood, S., Woodley, C., Woznicka, U., Wright, J., Wu, J., Yao, L., Yapp, D., Yavorskij, V., Yoo, M. G., Yorkshades, J., Young, C., Young, D., Young, I. D., Zabolotny, W., Zacks, J., Zagorski, R., Zaitsev, F. S., Zanino, R., Zaroschi, V., Zastrow, K. D., Zeidner, W., Ziolkowski, A., Zoita, V., Zoletnik, S., Zychor, I., and Jet, Contributors
- Subjects
Nuclear and High Energy Physics ,Materials science ,Fuel retention ,Tungsten coating ,Materials Science (miscellaneous) ,Nuclear engineering ,complex mixtures ,114 Physical sciences ,01 natural sciences ,010305 fluids & plasmas ,Fusion, plasma och rymdfysik ,0103 physical sciences ,Forensic engineering ,ta216 ,010306 general physics ,Deposition ,Jet (fluid) ,ta114 ,Divertor ,Dust ,Erosion ,Jet ,equipment and supplies ,lcsh:TK9001-9401 ,Fusion, Plasma and Space Physics ,Nuclear Energy and Engineering ,JET ,lcsh:Nuclear engineering. Atomic power ,human activities - Abstract
The work presented draws on new analysis of components removed following the second JET ITER-like wall campaign 2013–14 concentrating on the upper inner divertor, inner and outer divertor corners, lifetime issues relating to tungsten coatings on JET carbon fibre composite divertor tiles and dust/particulate generation. The results show that the upper inner divertor remains the region of highest deposition in the JET-ILW. Variations in plasma configurations between the first and second campaign have altered material migration to the corners of the inner and outer divertor. Net deposition is shown to be beneficial in the sense that it reduces W coating erosion, covers small areas of exposed carbon surfaces and even encapsulates particles. The work presented draws on new analysis of components removed following the second JET ITER-like wall campaign 2013–14 concentrating on the upper inner divertor, inner and outer divertor corners, lifetime issues relating to tungsten coatings on JET carbon fibre composite divertor tiles and dust/particulate generation. The results show that the upper inner divertor remains the region of highest deposition in the JET-ILW. Variations in plasma configurations between the first and second campaign have altered material migration to the corners of the inner and outer divertor. Net deposition is shown to be beneficial in the sense that it reduces W coating erosion, covers small areas of exposed carbon surfaces and even encapsulates particles.
- Published
- 2017
33. Elisa in Small Animal Hosts, Rodents, and Birds
- Author
-
BROWN, M, primary, BRADBURY, J, additional, and DAVIS, J, additional
- Published
- 1996
- Full Text
- View/download PDF
34. TRAINING NEUROFUZZY SYSTEMS
- Author
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Mills, D.J., primary, Brown, M., additional, and Harris, C.J., additional
- Published
- 1995
- Full Text
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35. ADVANCES IN NEUROFUZZY ALGORITHMS FOR REAL TIME MODELLING, CONTROL AND ESTIMATION
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Harris, C.J., primary and Brown, M., additional
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- 1995
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36. Cationic Bactericidal Peptides
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Hancock, R.E.W., primary, Falla, T., additional, and Brown, M., additional
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- 1995
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37. Destructive and non-destructive testing methods for characterization and detection of machining induced white layer: A review paper
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Brown, M., Wright, D., M'Saoubi, R., McGourly, J., Wallis, M., Mantle, A., Crawforth, P., and Ghadbeigi, H.
- Abstract
The presence of machining-induced white layer in the near-surface of critical aeroengine alloys has a detrimental effect on the lifetime of a component. Present techniques for identifying and characterizing white layer, such as optical microscopy and hardness testing, whilst effective, are destructive, costly and time-consuming. Non-destructive testing methods may, therefore, offer improvements to the process of white layer detection. This paper discusses the formation mechanisms and the defining physical properties of machining-induced white layers before offering a comprehensive review of the current state-of-the-art in both destructive and non-destructive testing methods for detecting this anomalous surface feature.
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- 2018
38. Loss-of-function nuclear factor κB subunit 1 (NFKB1) variants are the most common monogenic cause of common variable immunodeficiency in Europeans
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Tuijnenburg, P., Lango Allen, H., Burns, S.O., Greene, D., Jansen, M.H., Staples, E., Stephens, J., Carss, K.J., Biasci, D., Baxendale, H., Thomas, M., Chandra, A., Kiani-Alikhan, S., Longhurst, H.J., Seneviratne, S.L., Oksenhendler, E., Simeoni, I., de Bree, G.J., Tool, A.T.J., van Leeuwen, E.M.M., Ebberink, E.H.T.M., Meijer, A.B., Tuna, S., Whitehorn, D., Brown, M., Turro, E., Thrasher, A.J., Smith, K.G.C., Thaventhiran, J.E., Kuijpers, T.W., Adhya, Z., Alachkar, H., Anantharachagan, A., Antrobus, R., Arumugakani, G., Bacchelli, C., Bethune, C., Bibi, S., Boardman, B., Booth, C., Browning, M., Brownlie, M., Burns, S., Clifford, H., Cooper, N., Davies, S., Dempster, J., Devlin, L., Doffinger, R., Drewe, E., Edgar, D., Egner, W., El-Shanawany, T., Gaspar, B., Ghurye, R., Gilmour, K., Goddard, S., Gordins, P., Grigoriadou, S., Hackett, S., Hague, R., Harper, L., Hayman, G., Herwadkar, A., Hughes, S., Huissoon, A., Jolles, S., Jones, J., Kelleher, P., Klein, N., Kuijpers, T., Kumararatne, D., Laffan, J., Allen, H.L., Lear, S., Longhurst, H., Lorenzo, L., Maimaris, J., Manson, A., McDermott, E., Millar, H., Mistry, A., Morrisson, V., Murng, S., Nasir, I., and Nejentsev, S.
- Abstract
Background: The genetic cause of primary immunodeficiency disease (PID) carries prognostic information. Objective: We conducted a whole-genome sequencing study assessing a large proportion of the NIHR BioResource–Rare Diseases cohort. Methods: In the predominantly European study population of principally sporadic unrelated PID cases (n = 846), a novel Bayesian method identified nuclear factor κB subunit 1 (NFKB1) as one of the genes most strongly associated with PID, and the association was explained by 16 novel heterozygous truncating, missense, and gene deletion variants. This accounted for 4% of common variable immunodeficiency (CVID) cases (n = 390) in the cohort. Amino acid substitutions predicted to be pathogenic were assessed by means of analysis of structural protein data. Immunophenotyping, immunoblotting, and ex vivo stimulation of lymphocytes determined the functional effects of these variants. Detailed clinical and pedigree information was collected for genotype-phenotype cosegregation analyses. Results: Both sporadic and familial cases demonstrated evidence of the noninfective complications of CVID, including massive lymphadenopathy (24%), unexplained splenomegaly (48%), and autoimmune disease (48%), features prior studies correlated with worse clinical prognosis. Although partial penetrance of clinical symptoms was noted in certain pedigrees, all carriers have a deficiency in B-lymphocyte differentiation. Detailed assessment of B-lymphocyte numbers, phenotype, and function identifies the presence of an increased CD21lowB-cell population. Combined with identification of the disease-causing variant, this distinguishes between healthy subjects, asymptomatic carriers, and clinically affected cases. Conclusion: We show that heterozygous loss-of-function variants in NFKB1 are the most common known monogenic cause of CVID, which results in a temporally progressive defect in the formation of immunoglobulin-producing B cells.
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- 2018
39. Optogenetic stimulation of the cochlear nucleus using channelrhodopsin-2 evokes activity in the central auditory pathways
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Massachusetts Institute of Technology. Department of Biological Engineering, Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology. Media Laboratory, McGovern Institute for Brain Research at MIT, Program in Media Arts and Sciences (Massachusetts Institute of Technology), Boyden, Edward, Darrow, Keith N., Slama, Michaël C.C., Kozin, Elliott D., Owoc, Maryanna, Hancock, Kenneth, Kempfle, Judith, Edge, Albert, Lacour, Stephanie, Polley, Daniel, Brown, M. Christian, Lee, Daniel J., Massachusetts Institute of Technology. Department of Biological Engineering, Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology. Media Laboratory, McGovern Institute for Brain Research at MIT, Program in Media Arts and Sciences (Massachusetts Institute of Technology), Boyden, Edward, Darrow, Keith N., Slama, Michaël C.C., Kozin, Elliott D., Owoc, Maryanna, Hancock, Kenneth, Kempfle, Judith, Edge, Albert, Lacour, Stephanie, Polley, Daniel, Brown, M. Christian, and Lee, Daniel J.
- Abstract
Optogenetics has become an important research tool and is being considered as the basis for several neural prostheses. However, few studies have applied optogenetics to the auditory brainstem. This study explored whether optical activation of the cochlear nucleus (CN) elicited responses in neurons in higher centers of the auditory pathway and whether it elicited an evoked response. Viral-mediated gene transfer was used to express channelrhodopsin-2 (ChR2) in the mouse CN. Blue light was delivered via an optical fiber placed near the surface of the infected CN and recordings were made in higher-level centers. Optical stimulation evoked excitatory multiunit spiking activity throughout the tonotopic axis of the central nucleus of the inferior colliculus (IC) and the auditory cortex (Actx). The pattern and magnitude of IC activity elicited by optical stimulation was comparable to that obtained with a 50 dB SPL acoustic click. This broad pattern of activity was consistent with histological confirmation of green fluorescent protein (GFP) label of cell bodies and axons throughout the CN. Increasing pulse rates up to 320 Hz did not significantly affect threshold or bandwidth of the IC responses, but rates higher than 50 Hz resulted in desynchronized activity. Optical stimulation also evoked an auditory brainstem response, which had a simpler waveform than the response to acoustic stimulation. Control cases showed no responses to optical stimulation. These data suggest that optogenetic control of central auditory neurons is feasible, but opsins with faster channel kinetics may be necessary to convey information at rates typical of many auditory signals.
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- 2017
40. Temporal Resolution of ChR2 and Chronos in an Optogenetic-based Auditory Brainstem Implant Model: Implications for the Development and Application of Auditory Opsins
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Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology. Media Laboratory, McGovern Institute for Brain Research at MIT, Boyden, Edward Stuart, Hight, Ariel Edward, Kozin, Elliott D., Darrow, Keith, Lehmann, Ashton, Brown, M. Christian, Lee, Daniel J., Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology. Media Laboratory, McGovern Institute for Brain Research at MIT, Boyden, Edward Stuart, Hight, Ariel Edward, Kozin, Elliott D., Darrow, Keith, Lehmann, Ashton, Brown, M. Christian, and Lee, Daniel J.
- Abstract
Available in PMC 2015 June 14, Contemporary auditory brainstem implant (ABI) performance is limited by reliance on electrical neurostimulation with its accompanying channel cross talk and current spread to non-auditory neurons. A new generation ABI based on optogenetic technology may ameliorate limitations fundamental to electrical stimulation. The most widely studied opsin is channelrhodopsin-2 (ChR2); however, its relatively slow kinetic properties may prevent the encoding of auditory information at high stimulation rates. In the present study, we compare the temporal resolution of light-evoked responses of ChR2 to a recently developed fast opsin, Chronos, to ChR2 in a murine ABI model. Viral mediated gene transfer via a posterolateral craniotomy was used to express Chronos or ChR2 in the cochlear nucleus (CN). Following a four to eight week incubation period, blue light (473 nm) was delivered via an optical fiber placed directly on the surface of the infected CN, and neural activity was recorded in the contralateral inferior colliculus (IC). Both ChR2 and Chronos evoked sustained responses to all stimuli, even at high pulse rates. In addition, optical stimulation evoked excitatory responses throughout the tonotopic axis of the IC. Synchrony of the light-evoked response to stimulus rates of 14–448 pulses/s was higher in Chronos compared to ChR2 mice (p < 0.05 at 56, 168, and 224 pulses/s). Our results demonstrate that Chronos has the ability to drive the auditory system at higher stimulation rates than ChR2 and may be a more ideal opsin for manipulation of auditory pathways in future optogenetic-based neuroprostheses.
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- 2016
41. ACTIONS OF NEUROTENSIN UPON SINGLE NEURONE ACTIVITY IN DIFFERENT REGIONS OF THE RAT BRAIN
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Zieglgansberger, W., primary, Siggins, G., additional, Brown, M., additional, Vale, W., additional, and Bloom, F., additional
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- 1978
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42. UTILIZATION OF TISSUE CULTURE TECHNIQUES TO CLONE AN INSECT CELL LINE AND TO CHARACTERIZE STRAINS OF BACULOVIRUS
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Faulkner, P., primary, Brown, M., additional, and Potter, K.N., additional
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- 1976
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43. LIST OF CONTRIBUTORS AND DISCUSSANTS
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Archer, J.A., primary, Arimura, A., additional, Aurbach, G.D., additional, Axelrod, J., additional, Bar, R.S., additional, Bartke, A., additional, Bartosik, D.B., additional, Bartter, F.C., additional, Beato, M., additional, Beck, J.C., additional, Bell, N.H., additional, Bennett, V., additional, Birnbaumer, L., additional, Bogdanove, E.M., additional, Boss, B., additional, Boyar, R.M., additional, Bransome, E.D., additional, Brazeau, P., additional, Brodie, H.J., additional, Brown, J.C., additional, Brown, M., additional, Burgus, R., additional, Burrow, G.N., additional, Campbell, G.T., additional, Cataland, S., additional, Chang, Kwen-Jen, additional, Chase, L.R., additional, Cohen, S.L., additional, Colman, P., additional, Condliffe, P.G., additional, Cross, B.A., additional, Cuatrecasas, P., additional, Davies, I.J., additional, De Meyts, P., additional, Dobyns, B.M., additional, Dratman, M.B., additional, Drosdonsky, M., additional, Dryburgh, J.R., additional, Dupré, J., additional, Dyball, R.E.J., additional, Dyer, R.G., additional, Feigelson, P., additional, Flores, F., additional, Freychet, P., additional, Friesen, H.G., additional, Funder, J.W., additional, Gavin, J.R., additional, Gay, V.L., additional, George, J.M., additional, Gill, J.R., additional, Glick, S., additional, Goldfine, I.D., additional, Goodman, H.M., additional, Gorden, P., additional, Creep, R.O., additional, Greer, M.A., additional, Guillemin, R., additional, Gupta, S.L., additional, Haksar, A., additional, Hanjan, S.N.S., additional, Hedge, G.A., additional, Hellman, L., additional, Herman, M., additional, Hershman, J.M., additional, Hollenberg, M.D., additional, Jewelewicz, R., additional, Jones, C.W., additional, Kahn, C.R., additional, Kalimi, M., additional, Kapen, S., additional, Karsch, F.J., additional, Kenny, A.D., additional, Killewich, L.A., additional, Kitay, J.I., additional, Knobil, E., additional, Konishi, J., additional, Kowal, J., additional, Krieger, D.T., additional, Krishnaraj, R., additional, Kriss, J.P., additional, Kuhn, M., additional, Kumar, N., additional, Lasley, B.L., additional, Leblanc, H., additional, Lequin, R.M., additional, Lesniak, M.A., additional, Levy, R., additional, Lincoln, D.W., additional, Ling, N., additional, Lipsett, M.B., additional, McCann, S.M., additional, McKenzie, J.M., additional, McKnight, G.S., additional, Malarky, W.B., additional, Marks, B.H., additional, Megyesi, K., additional, Melby, J.C., additional, Monder, C., additional, Morris, J.F., additional, Naftolin, F., additional, Neville, D.M., additional, Nikitovitch-Winer, M.B., additional, Nillius, S.J., additional, Nolin, J.M., additional, Palacios, R., additional, Pandian, M.R., additional, Parsons, J.A., additional, Petro, Z., additional, Pickering, B.T., additional, Posner, B.I., additional, Raiti, S., additional, Ramaley, J.A., additional, Reddy, V.V., additional, Rice, B.F., additional, Rivier, C., additional, Rivier, J., additional, Roberts, J.S., additional, Rolland, R., additional, Rosenbloom, A.L., additional, Ross, S.A., additional, Roth, J., additional, Ryan, K.J., additional, Samaan, N., additional, Santen, R.J., additional, Saxena, R.K., additional, Schimke, R.T., additional, Schonbaum, E., additional, Schutz, G., additional, Schwartz, N.B., additional, Shaikh, A.A., additional, Shapiro, D.J., additional, Sherins, R.J., additional, Siler, T.M., additional, Sokol, H.W., additional, Soil, A.H., additional, Sterling, K., additional, Sulhvan, D., additional, Sunde, D., additional, Takaoka, Y., additional, Talwar, G.P., additional, Theoharides, T.C., additional, Vaitukaitis, J.L., additional, Vale, W., additional, Valtin, H., additional, Vander Laan, W.P., additional, Villee, C.A., additional, Wang, C.F., additional, Weick, R.F., additional, Weisz, J., additional, Weitzman, E.D., additional, White, A., additional, White, R.J., additional, Wolin, L., additional, and Yen, S.S.C., additional
- Published
- 1975
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44. Age-related changes in neuroactive steroid levels in 3xTg-AD mice
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Caruso, D., Barron, A. M., Brown, M. A., Abbiati, F., Carrero, Paloma, Pike, C. J., García-Segura, Luis M., Melcangi, R. C., Caruso, D., Barron, A. M., Brown, M. A., Abbiati, F., Carrero, Paloma, Pike, C. J., García-Segura, Luis M., and Melcangi, R. C.
- Abstract
Although neuroactive steroids exert neuroprotective actions in different experimental models of neurodegenerative diseases, including those of Alzheimer's disease (AD), their relationships with aged related physiologic and pathologic brain changes remain to be clarified. In this study the levels of pregnenolone, dehydroepiandrosterone, progesterone, dihydroprogesterone, tetrahydroprogesterone, isopregnanolone, testosterone, dihydrotestosterone, 5α-androstane-3α,17β-diol, 5α-androstane-3β,17β-diol, 17α-estradiol, and 17β-estradiol were assessed in the limbic region of young adult (7 months) and aged (24 months) male wild type and triple transgenic AD mice. Age related neuropathological changes in AD brains, such as β-amyloid accumulation and gliosis, were associated with modified levels of specific neuroactive steroids and particularly with changes in the levels of progesterone and testosterone metabolites. The altered levels of neuroactive steroids in aged AD brains might impact on the activation of neuroprotective signaling mediated by classic and nonclassic steroid receptors, like the gamma-aminobuttyric acid (GABA)-A receptor. © 2013 Elsevier Inc.
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- 2013
45. Production of microalgal concentrates by flocculation and their assessment as aquaculture feeds
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Knuckey, R, Brown, M, Robert, Rene, Frampton, D, Knuckey, R, Brown, M, Robert, Rene, and Frampton, D
- Abstract
A novel technique was developed for the flocculation of marine microalgae commonly used in aquaculture. The process entailed an adjustment of pH of culture to between 10 and 10.6 using NaOH, followed by addition of a non-ionic polymer Magnafloc LT-25 to a final concentration of 0.5 mg L−1. The ensuing flocculate was harvested, and neutralised giving a final concentration factor of between 200- and 800-fold. This process was successfully applied to harvest cells of Chaetoceros calcitrans, C. muelleri, Thalassiosira pseudonana, Attheya septentrionalis, Nitzschia closterium, Skeletonema sp., Tetraselmis suecica and Rhodomonas salina, with efficiencies ≥80%. The process was rapid, simple and inexpensive, and relatively cost neutral with increasing volume (cf. concentration by centrifugation). Harvested material was readily disaggregated to single cell suspensions by dilution in seawater and mild agitation. Microscopic examination of the cells showed them to be indistinguishable from corresponding non-flocculated cells. Chlorophyll analysis of concentrates prepared from cultures of ≤130 L showed minimal degradation after 2 weeks storage. Concentrates of T. pseudonana prepared using pH-induced flocculation gave better growth of juvenile Pacific oysters (Crassostrea gigas) than concentrates prepared by ferric flocculation, or centrifuged concentrates using a cream separator or laboratory centrifuge. In follow up experiments, concentrates prepared from 1000 L Chaetoceros muelleri cultures were effective as supplementary diets to improve the growth of juvenile C. gigas and the scallop Pecten fumatus reared under commercial conditions, though not as effective as the corresponding live algae. The experiments demonstrated a proof-of-concept for a commercial application of concentrates prepared by flocculation, especially for use at a remote nursery without on-site mass-algal culture facilities.
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- 2006
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46. Cochlear inner hair cells: Effects of transient asphyxia on intracellular potentials
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Kresge Hearing Research Institute, University of Michigan Medical School, 1301, E. Ann St., Ann Arbor, MI 48109, U.S.A., Brown, M. Christian, Nuttall, Alfred L., Masta, Robert I., Lawrence, Merle, Kresge Hearing Research Institute, University of Michigan Medical School, 1301, E. Ann St., Ann Arbor, MI 48109, U.S.A., Brown, M. Christian, Nuttall, Alfred L., Masta, Robert I., and Lawrence, Merle
- Abstract
Intracellular potentials were recorded from inner hair cells in the guinea pig cochlea. Transient asphyxia was induced by interrupting respiration for brief periods. Asphyxia caused a hyperpolarization of the resting membrane potential (resting Em). The hyperpolarization averaged 2.9 mV for 30 s asphyxias and 5.7 mV for 45 s asphyxias. The membrane potential recovered quickly after normal ventilation was resumed. Asphyxia also induced a rapid and profound decrease of the d.c. receptor potential in response to moderate intensity tone bursts at the characteristic frequency of the inner hair cell. At maximal depression, the receptor potential was reduced about 60% for a 30 s asphyxia and 100% for a 45 s asphyxia. The receptor potential recovered slowly after normal ventilation was resumed. A similar percent reduction and time course of recovery were observed for the a.c. receptor potential. In recordings from the same animals, the round window compound action potential (CAP) was as severely depressed by asphyxia as the hair cell receptor potentials. The time course of recovery for the CAP was similar to the slow recovery of the d.c. receptor potential. In contrast, the round window cochlear microphonics (CM) and the endolymphatic potential (EP) were affected less by asphyxia and recovered quickly after ventilation was resumed. Frequency tuning curves (FTCs) for the d.c. receptor potential were measured during the period of maximal receptor potential depression. These FTCs showed decreased tip sensitivity and a decrease in sharpness of tuning, as measured by the Q10. These changes were fully reversible. Low frequency (tail) segments of the FTCs were much less affected by asphyxia. The inner hair cell FTC changes during asphyxia were compared with neural FTC changes reported by other investigators. The similarities lead us to the conclusion that the inner hair cell and the auditory neural response to sound are equally sensitive to asphyxia.
- Published
- 2006
47. RF sheath modeling of experimentally observed plasma surface interactions with the JET ITER-Like Antenna
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Krivska, A., Bobkov, V., Colas, L., Dumortier, P., Durodie, F., Jacquet, P., Klepper, C. C., Milanesio, D., Urbanczyk, G., Abduallev, S., Abhangi, M., Abreu, P., Afzal, M., Aggarwal, K. M., Ahlgren, T., Ahn, J. H., Aho-Mantila, L., Aiba, N., Airila, M., Albanese, R., Aldred, V., Alegre, D., Alessi, E., Aleynikov, P., Alfier, A., Alkseev, A., Allinson, M., Alper, B., Alves, E., Ambrosino, G., Ambrosino, R., Amicucci, L., Amosov, V., Sunden, E. Andersson, Angelone, M., Anghel, M., Angioni, C., Appel, L., Appelbee, C., Arena, P., Ariola, M., Arnichand, H., Arshad, S., Ash, A., Ashikawa, N., Aslanyan, V., Asunta, O., Auriemma, F., Austin, Y., Avotina, L., Axton, M. D., Ayres, C., Bacharis, M., Baciero, A., Baiao, D., Bailey, S., Baker, A., Balboa, I., Balden, M., Balshaw, N., Bament, R., Banks, J. W., Baranov, Y. F., Barnard, M. A., Barnes, D., Barnes, M., Barnsley, R., Wiechec, A. Baron, Orte, L. Barrera, Baruzzo, M., Basiuk, V., Bassan, M., Bastow, R., Batista, A., Batistoni, P., Baughan, R., Bauvir, B., Baylor, L., Bazylev, B., Beal, J., Beaumont, P. S., Beckers, M., Beckett, B., Becoulet, A., Bekris, N., Beldishevski, M., Bell, K., Belli, F., Bellinger, M., Belonohy, E., Ben Ayed, N., Benterman, N. A., Bergsaker, H., Bernardo, J., Bernert, M., Berry, M., Bertalot, L., Besliu, C., Beurskens, M., Bieg, B., Bielecki, J., Biewer, T., Bigi, M., Bilkova, P., Binda, F., Bisoffi, A., Bizarro, J. P. S., Bjorkas, C., Blackburn, J., Blackman, K., Blackman, T. R., Blanchard, P., Blatchford, P., Boboc, A., Bodnar, G., Bogar, O., Bolshakova, I., Bolzonella, T., Bonanomi, N., Bonelli, F., Boom, J., Booth, J., Borba, D., Borodin, D., Borodkina, I., Botrugno, A., Bottereau, C., Boulting, P., Bourdelle, C., Bowden, M., Bower, C., Bowman, C., Boyce, T., Boyd, C., Boyer, H. J., Bradshaw, J. M. A., Braic, V., Bravanec, R., Breizman, B., Bremond, S., Brennan, P. D., Breton, S., Brett, A., Brezinsek, S., Bright, M. D. J., Brix, M., Broeckx, W., Brombin, M., Broslawski, A., Brown, D. P. D., Brown, M., Bruno, E., Bucalossi, J., Buch, J., Buchanan, J., Buckley, M. A., Budny, R., Bufferand, H., Bulman, M., Bulmer, N., Bunting, P., Buratti, P., Burckhart, A., Buscarino, A., Busse, A., Butler, N. K., Bykov, I., Byrne, J., Cahyna, P., Calabro, G., Calvo, I., Camenen, Y., Camp, P., Campling, D. C., Cane, J., Cannas, B., Capel, A. J., Card, P. J., Cardinali, A., Carman, P., Carr, M., Carralero, D., Carraro, L., Carvalho, B. B., Carvalho, I., Carvalho, P., Casson, F. J., Castaldo, C., Catarino, N., Caumont, J., Causa, F., Cavazzana, R., Cave-Ayland, K., Cavinato, M., Cecconello, M., Ceccuzzi, S., Cecil, E., Cenedese, A., Cesario, R., Challis, C. D., Chandler, M., Chandra, D., Chang, C. S., Chankin, A., Chapman, I. T., Chapman, S. C., Chernyshova, M., Chitarin, G., Ciraolo, G., Ciric, D., Citrin, J., Clairet, F., Clark, E., Clark, M., Clarkson, R., Clatworthy, D., Clements, C., Cleverly, M., Coad, J. P., Coates, P. A., Cobalt, A., Coccorese, V., Cocilovo, V., Coda, S., Coelho, R., Coenen, J. W., Coffey, I., Collins, S., Conka, D., Conroy, S., Conway, N., Coombs, D., Cooper, D., Cooper, S. R., Corradino, C., Corre, Y., Corrigan, G., Cortes, S., Coster, D., Couchman, A. S., Cox, M. P., Craciunescu, T., Cramp, S., Craven, R., Crisanti, F., Croci, G., Croft, D., Crombe, K., Crowe, R., Cruz, N., Cseh, G., Cufar, A., Cullen, A., Curuia, M., Czarnecka, A., Dabirikhah, H., Dalgliesh, P., Dalley, S., Dankowski, J., Darrow, D., Davies, O., Davis, W., Day, C., Day, I. E., De Bock, M., Castro, A. De, Cal, E. De La, Luna, E. De La, De Masi, G., Pablos, J. L. De, De Temmerman, G., De Tommasi, G., Vries, P. De, Deakin, K., Deane, J., Agostini, F. Degli, Dejarnac, R., Delabie, E., Harder, N. Den, Dendy, R. O., Denis, J., Denner, P., Devaux, S., Devynck, P., Di Maio, F., Di Siena, A., Di Troia, C., Dinca, P., D’Inca, R., Ding, B., Dittmar, T., Doerk, H., Doerner, R. P., Donne, T., Dorling, S. E., Dormido-Canto, S., Doswon, S., Douai, D., Doyle, P. T., Drenik, A., Drewelow, P., Drews, P., Duckworth, Ph, Dumont, R., Dunai, D., Dunne, M., Duran, I., Dutta, P., Duval, B. P., Dux, R., Dylst, K., Dzysiuk, N., Edappala, P. V., Edmond, J., Edwards, A. M., Edwards, J., Eich, Th, Ekedahl, A., El-Jorf, R., Elsmore, C. G., Enachescu, M., Ericsson, G., Eriksson, F., Eriksson, J., Eriksson, L. G., Esposito, B., Esquembri, S., Esser, H. G., Esteve, D., Evans, B., Evans, G. E., Evison, G., Ewart, G. D., Fagan, D., Faitsch, M., Falie, D., Fanni, A., Fasoli, A., Faustin, J. M., Fawlk, N., Fazendeiro, L., Fedorczak, N., Felton, R. C., Fenton, K., Fernades, A., Fernandes, H., Ferreira, J., Fessey, J. A., Fevrier, O., Ficker, O., Field, A., Fietz, S., Figueiredo, A., Figueiredo, J., Fil, A., Finburg, P., Firdaouss, M., Fischer, U., Fittill, L., Fitzgerald, M., Flammini, D., Flanagan, J., Fleming, C., Flinders, K., Fonnesu, N., Fontdecaba, J. M., Formisano, A., Forsythe, L., Fortuna, L., Fortuna-Zalesna, E., Fortune, M., Foster, S., Franke, T., Franklin, T., Frasca, M., Frassinetti, L., Freisinger, M., Fresa, R., Frigione, D., Fuchs, V., Fuller, D., Futatani, S., Fyvie, J., Gal, K., Galassi, D., Galazka, K., Galdon-Quiroga, J., Gallagher, J., Gallart, D., Galvao, R., Gao, X., Gao, Y., Garcia, J., Garcia-Carrasco, A., Garcia-Munoz, M., Gardarein, J.-L., Garzotti, L., Gaudio, P., Gauthier, E., Gear, D. F., Gee, S. J., Geiger, B., Gelfusa, M., Gerasimov, S., Gervasini, G., Gethins, M., Ghani, Z., Ghate, M., Gherendi, M., Giacalone, J. C., Giacomelli, L., Gibson, C. S., Giegerich, T., Gil, C., Gil, L., Gilligan, S., Gin, D., Giovannozzi, E., Girardo, J. 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Physics::Plasma Physics ,7. Clean energy - Abstract
Waves in the Ion Cyclotron Range of Frequencies (ICRF) enhance local Plasma-Surface Interactions (PSI) near the wave launchers and magnetically-connected objects via Radio-Frequency (RF) sheath rectification. ITER will use 20MW of ICRF power over long pulses, questioning the long-term impact of RF-enhanced localized erosion on the lifetime of its Beryllium (Be) wall. Recent dedicated ICRF-heated L-mode discharges documented this process on JET for different types of ICRF antennas. Using visible spectroscopy in JET ICRF-heated L-mode discharges, poloidally-localized regions of enhanced (by ∼2–4x) Be I and Be II light emission were observed on two outboard limiters magnetically connected to the bottom of the active ITER-Like Antenna (ILA). The observed RF-PSI induced by the ILA was qualitatively comparable to that induced by the JET standard, type-A2 antennas, for similar strap toroidal phasing and connection geometries. The Be II line emission was found more intense when powering the bottom half of the ILA rather than its top half. Conversely, more pronounced SOL density modifications were observed with only top array operation, on field lines connected to the top half of the ILA. So far the near-field modeling of the ILA with antenna code TOPICA (Torino Polytechnic Ion Cyclotron Antenna), using curved antenna model, was partially able to reproduce qualitatively the observed phenomena. A quantitative discrepancy persisted between the observed Be source amplification and the calculated, corresponding increases in E// field at the magnetically connected locations to the ILA when changing from only top to only bottom half antenna operation. This paper revisits these current drive phased and half-ILA powered cases using for the new simulations flat model of the ILA and more realistic antenna feeding to calculate the E// field maps with TOPICA code. Further, the Self-consistent Sheaths and Waves for Ion Cyclotron Heating Slow Wave (SSWICH-SW) code, which couples slow wave evanescence with DC Scrape-Off Layer (SOL) biasing, is used to estimate the poloidal distribution of rectified RF-sheath Direct Current (DC) potential VDC in the private SOL between the ILA poloidal limiters. The approach so far was limited to correlating the observed, enhanced emission regions at the remote limiters to the antenna near-electric fields, as calculated by TOPICA. The present approach includes also a model for the rectification of these near-fields in the private SOL of the ILA. With the improved approach, when comparing only top and only bottom half antenna feeding, we obtained good qualitative correlation between all experimental measurements and the calculated local variations in the E// field and VDC potential.
48. Investigation of deuterium trapping and release in the JET divertor during the third ILW campaign using TDS
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Likonen, J., Heinola, K., De Backer, A., Baron-Wiechec, A., Catarino, N., Jepu, I., Ayres, C. F., Coad, P., Matthews, G. F., Widdowson, A., Abduallev, S., Abhangi, M., Abreu, P., Afzal, M., Aggarwal, K. M., Ahlgren, T., Ahn, J. H., Aho-Mantila, L., Aiba, N., Airila, M., Albanese, R., Aldred, V., Alegre, D., Alessi, E., Aleynikov, P., Alfier, A., Alkseev, A., Allinson, M., Alper, B., Alves, E., Ambrosino, G., Ambrosino, R., Amicucci, L., Amosov, V., Sunden, E. Andersson, Angelone, M., Anghel, M., Angioni, C., Appel, L., Appelbee, C., Arena, P., Ariola, M., Arnichand, H., Arshad, S., Ash, A., Ashikawa, N., Aslanyan, V., Asunta, O., Auriemma, F., Austin, Y., Avotina, L., Axton, M. D., Ayres, C., Bacharis, M., Baciero, A., Baiao, D., Bailey, S., Baker, A., Balboa, I., Balden, M., Balshaw, N., Bament, R., Banks, J. W., Baranov, Y. F., Barnard, M. A., Barnes, D., Barnes, M., Barnsley, R., Wiechec, A. Baron, Orte, L. Barrera, Baruzzo, M., Basiuk, V., Bassan, M., Bastow, R., Batista, A., Batistoni, P., Baughan, R., Bauvir, B., Baylor, L., Bazylev, B., Beal, J., Beaumont, P. S., Beckers, M., Beckett, B., Becoulet, A., Bekris, N., Beldishevski, M., Bell, K., Belli, F., Bellinger, M., Belonohy, E., Ben Ayed, N., Benterman, N. A., Bergsaker, H., Bernardo, J., Bernert, M., Berry, M., Bertalot, L., Besliu, C., Beurskens, M., Bieg, B., Bielecki, J., Biewer, T., Bigi, M., Bilkova, P., Binda, F., Bisoffi, A., Bizarro, J. P. S., Bjorkas, C., Blackburn, J., Blackman, K., Blackman, T. R., Blanchard, P., Blatchford, P., Bobkov, V., Boboc, A., Bodnar, G., Bogar, O., Bolshakova, I., Bolzonella, T., Bonanomi, N., Bonelli, F., Boom, J., Booth, J., Borba, D., Borodin, D., Borodkina, I., Botrugno, A., Bottereau, C., Boulting, P., Bourdelle, C., Bowden, M., Bower, C., Bowman, C., Boyce, T., Boyd, C., Boyer, H. J., Bradshaw, J. M. A., Braic, V., Bravanec, R., Breizman, B., Bremond, S., Brennan, P. D., Breton, S., Brett, A., Brezinsek, S., Bright, M. D. J., Brix, M., Broeckx, W., Brombin, M., Broslawski, A., Brown, D. P. D., Brown, M., Bruno, E., Bucalossi, J., Buch, J., Buchanan, J., Buckley, M. A., Budny, R., Bufferand, H., Bulman, M., Bulmer, N., Bunting, P., Buratti, P., Burckhart, A., Buscarino, A., Busse, A., Butler, N. K., Bykov, I., Byrne, J., Cahyna, P., Calabro, G., Calvo, I., Camenen, Y., Camp, P., Campling, D. C., Cane, J., Cannas, B., Capel, A. J., Card, P. J., Cardinali, A., Carman, P., Carr, M., Carralero, D., Carraro, L., Carvalho, B. B., Carvalho, I., Carvalho, P., Casson, F. J., Castaldo, C., Caumont, J., Causa, F., Cavazzana, R., Cave-Ayland, K., Cavinato, M., Cecconello, M., Ceccuzzi, S., Cecil, E., Cenedese, A., Cesario, R., Challis, C. D., Chandler, M., Chandra, D., Chang, C. S., Chankin, A., Chapman, I. T., Chapman, S. 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13. Climate action - Abstract
Selected set of samples from JET ITER-Like Wall (JET-ILW) divertor tiles exposed in 2015–2016 has been analysed using Thermal Desorption Spectrometry (TDS). The deuterium (D) amounts obtained with TDS were compared with Nuclear Reaction Analysis (NRA). The highest amount of D was found on the top part of inner divertor which has regions with the thickest deposited layers as for divertor tiles removed in 2014. This area resides deep in the scrape-off layer and plasma configurations for the second (ILW-2, 2013–2014) and the third (ILW-3, 2015–2016) JET-ILW campaigns were similar. Agreement between TDS and NRA is good on the apron of Tile 1 and on the upper vertical region whereas on the lower vertical region of Tile 1 the NRA results are clearly smaller than the TDS results. Inner divertor Tile 3 has somewhat less D than Tiles 0 and 1, and the D amount decreases towards the lower part of the tile. The D retention at the divertor inner and outer corner regions is not symmetric as there is more D retention poloidally at the inner than at the outer divertor corner. In most cases the TDS spectra for the ILW-3 samples are different from the corresponding ILW-2 spectra because HD and D2 release occurs at higher temperatures than from the ILW-2 samples indicating that the low energy traps have been emptied during the plasma operations and that D is either in the energetically deep traps or located deeper in the sample.
49. The effect of beryllium oxide on retention in JET ITER-like wall tiles
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Makepeace, C., Pardanaud, C., Roubin, P., Borodkina, I., Ayres, C., Coad, P., Baron-Wiechec, A., Jepu, I., Heinola, K., Widdowson, A., Lozano-Perez, S., Abduallev, S., Abhangi, M., Abreu, P., Afzal, M., Aggarwal, K. M., Ahlgren, T., Ahn, J. H., Aho-Mantila, L., Aiba, N., Airila, M., Albanese, R., Aldred, V., Alegre, D., Alessi, E., Aleynikov, P., Alfier, A., Alkseev, A., Allinson, M., Alper, B., Alves, E., Ambrosino, G., Ambrosino, R., Amicucci, L., Amosov, V., Sunden, E. Andersson, Angelone, M., Anghel, M., Angioni, C., Appel, L., Appelbee, C., Arena, P., Ariola, M., Arnichand, H., Arshad, S., Ash, A., Ashikawa, N., Aslanyan, V., Asunta, O., Auriemma, F., Austin, Y., Avotina, L., Axton, M. D., Bacharis, M., Baciero, A., Baiao, D., Bailey, S., Baker, A., Balboa, I., Balden, M., Balshaw, N., Bament, R., Banks, J. W., Baranov, Y. F., Barnard, M. A., Barnes, D., Barnes, M., Barnsley, R., Wiechec, A. Baron, Orte, L. Barrera, Baruzzo, M., Basiuk, V., Bassan, M., Bastow, R., Batista, A., Batistoni, P., Baughan, R., Bauvir, B., Baylor, L., Bazylev, B., Beal, J., Beaumont, P. S., Beckers, M., Beckett, B., Becoulet, A., Bekris, N., Beldishevski, M., Bell, K., Belli, F., Bellinger, M., Belonohy, E., Ben Ayed, N., Benterman, N. A., Bergsaker, H., Bernardo, J., Bernert, M., Berry, M., Bertalot, L., Besliu, C., Beurskens, M., Bieg, B., Bielecki, J., Biewer, T., Bigi, M., Bilkova, P., Binda, F., Bisoffi, A., Bizarro, J. P. S., Bjorkas, C., Blackburn, J., Blackman, K., Blackman, T. R., Blanchard, P., Blatchford, P., Bobkov, V., Boboc, A., Bodnar, G., Bogar, O., Bolshakova, I., Bolzonella, T., Bonanomi, N., Bonelli, F., Boom, J., Booth, J., Borba, D., Borodin, D., Botrugno, A., Bottereau, C., Boulting, P., Bourdelle, C., Bowden, M., Bower, C., Bowman, C., Boyce, T., Boyd, C., Boyer, H. J., Bradshaw, J. M. A., Braic, V., Bravanec, R., Breizman, B., Bremond, S., Brennan, P. D., Breton, S., Brett, A., Brezinsek, S., Bright, M. D. J., Brix, M., Broeckx, W., Brombin, M., Broslawski, A., Brown, D. P. D., Brown, M., Bruno, E., Bucalossi, J., Buch, J., Buchanan, J., Buckley, M. A., Budny, R., Bufferand, H., Bulman, M., Bulmer, N., Bunting, P., Buratti, P., Burckhart, A., Buscarino, A., Busse, A., Butler, N. K., Bykov, I., Byrne, J., Cahyna, P., Calabro, G., Calvo, I., Camenen, Y., Camp, P., Campling, D. C., Cane, J., Cannas, B., Capel, A. J., Card, P. J., Cardinali, A., Carman, P., Carr, M., Carralero, D., Carraro, L., Carvalho, B. B., Carvalho, I., Carvalho, P., Casson, F. J., Castaldo, C., Catarino, N., Caumont, J., Causa, F., Cavazzana, R., Cave-Ayland, K., Cavinato, M., Cecconello, M., Ceccuzzi, S., Cecil, E., Cenedese, A., Cesario, R., Challis, C. D., Chandler, M., Chandra, D., Chang, C. S., Chankin, A., Chapman, I. T., Chapman, S. 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R., Mertens, Ph, Meshchaninov, S., Messiaen, A., Meyer, H., Mianowski, S., Michling, R., Middleton-Gear, D., Miettunen, J., Militello, F., Militello-Asp, E., Miloshevsky, G., Mink, F., Minucci, S., Miyoshi, Y., Mlynar, J., Molina, D., Monakhov, I., Moneti, M., Mooney, R., Moradi, S., Mordijck, S., Moreira, L., Moreno, R., Moro, F., Morris, A. W., Morris, J., Moser, L., Mosher, S., Moulton, D., Murari, A., Muraro, A., Murphy, S., Asakura, N. N., Na, Y. S., Nabais, F., Naish, R., Nakano, T., Nardon, E., Naulin, V., Nave, M. F. F., Nedzelski, I., Nemtsev, G., Nespoli, F., Neto, A., Neu, R., Neverov, V. S., Newman, M., Nicholls, K. J., Nicolas, T., Nielsen, A. H., Nielsen, P., Nilsson, E., Nishijima, D., Noble, C., Nocente, M., Nodwell, D., Nordlund, K., Nordman, H., Nouailletas, R., Nunes, I., Oberkofler, M., Odupitan, T., Ogawa, M. T., O’Gorman, T., Okabayashi, M., Olney, R., Omolayo, O., O’Mullane, M., Ongena, J., Orsitto, F., Orszagh, J., Oswuigwe, B. 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- Subjects
13. Climate action ,respiratory tract diseases - Abstract
Preliminary results investigating the microstructure, bonding and effect of beryllium oxide formation on retention in the JET ITER-like wall beryllium tiles, are presented. The tiles have been investigated by several techniques: Scanning Electron Microscopy (SEM) equipped with Energy Dispersive X-ray (EDX), Transmission Electron microscopy (TEM) equipped with EDX and Electron Energy Loss Spectroscopy (EELS), Raman Spectroscopy and Thermal Desorption Spectroscopy (TDS). This paper focuses on results from melted materials of the dump plate tiles in JET. From our results and the literature, it is concluded, beryllium can form micron deep oxide islands contrary to the nanometric oxides predicted under vacuum conditions. The deepest oxides analyzed were up to 2-micron thicknesses. The beryllium Deuteroxide (BeOxDy) bond was found with Raman Spectroscopy. Application of EELS confirmed the oxide presence and stoichiometry. Literature suggests these oxides form at temperatures greater than 700 °C where self-diffusion of beryllium ions through the surface oxide layer can occur. Further oxidation is made possible between oxygen plasma impurities and the beryllium ions now present at the wall surface. Under Ultra High Vacuum (UHV) nanometric Beryllium oxide layers are formed and passivate at room temperature. After continual cyclic heating (to the point of melt formation) in the presence of oxygen impurities from the plasma, oxide growth to the levels seen experimentally (approximately two microns) is proposed. This retention mechanism is not considered to contribute dramatically to overall retention in JET, due to low levels of melt formation. However, this mechanism, thought the result of operation environment and melt formation, could be of wider concern to ITER, dependent on wall temperatures.
50. Auditory responses to electric and infrared neural stimulation of the rat cochlear nucleus
- Author
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Verma, Rohit U., Guex, Amelie A., Hancock, Kenneth E., Durakovic, Nedim, Mckay, Colette M., Slama, Michael C. C., Brown, M. Christian, and Lee, Daniel J.
- Subjects
otorhinolaryngologic diseases ,sense organs - Abstract
In an effort to improve the auditory brainstem implant, a prosthesis in which user outcomes are modest, we applied electric and infrared neural stimulation (INS) to the cochlear nucleus in a rat animal model. Electric stimulation evoked regions of neural activation in the inferior colliculus and short-latency, multipeaked auditory brainstem responses (ABRs). Pulsed INS, delivered to the surface of the cochlear nucleus via an optical fiber, evoked broad neural activation in the inferior colliculus. Strongest responses were recorded when the fiber was placed at lateral positions on the cochlear nucleus, close to the temporal bone. INS-evoked ABRs were multipeaked but longer in latency than those for electric stimulation; they resembled the responses to acoustic stimulation. After deafening, responses to electric stimulation persisted, whereas those to INS disappeared, consistent with a reported "optophonic" effect, a laser-induced acoustic artifact. Thus, for deaf individuals who use the auditory brainstem implant, INS alone did not appear promising as a new approach. (C) 2014 Elsevier B.V. All rights reserved.
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