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Your search keyword '"Babu, Anish"' showing total 4 results
Start Over Author "Babu, Anish" Publisher elsevier
4 results on '"Babu, Anish"'

1. Contributors

Author

Abdelaziz, H.M., primary, Abdelmoneem, M.A., additional, Abdelsalam, K., additional, Agarwal, Sankalp, additional, Ahemad, Nafees, additional, Aleti, Rajeshwar Reddy, additional, Alibolandi, Mona, additional, Alsaqr, Ahmed, additional, Amreddy, Narsireddy, additional, Annaji, Manjusha, additional, Arnold, Robert D., additional, Babu, R. Jayachandra, additional, Babu, Anish, additional, Bilensoy, Erem, additional, Choudhury, Hira, additional, Dandela, Rambabu, additional, Dhapte, Vividha, additional, Dominic, Abishai, additional, Dubey, Sunil K., additional, Elkhodairy, K.A., additional, Elzoghby, Ahmed O., additional, Freag, M.S., additional, Gajbhiye, Kavita R., additional, Gajbhiye, Virendra, additional, Gorain, Bapi, additional, Gupta, Manish, additional, Handa, Mayank, additional, Hussain, Afzal, additional, Karpoormath, Rajshekhar, additional, Kashyap, Kanchan, additional, Kesharwani, Prashant, additional, Khurana, Rajneet Kaur, additional, Kohli, Kanchan, additional, Kokare, Chandrakanth, additional, Kumar, Pramod, additional, Lokesh, Siva B., additional, Mohapatra, Adityanarayan, additional, Munshi, Anupama, additional, Nlooto, Manimbulu, additional, Paknikar, Kishore M., additional, Pandey, Manisha, additional, Pardhi, Vishwas, additional, Park, In-Kyu, additional, Petkar, Kailash C., additional, Pokharkar, Varsha, additional, R. Gajbhiye, Kavita, additional, Ramesh, Rajagopal, additional, Ramezani, Mohammad, additional, Rehan, Farah, additional, Ruwali, Munindra, additional, Sayed, Nida, additional, Sehdev, Ash, additional, Shahriari, Mahsa, additional, Shukla, Rahul, additional, Singh, Sima, additional, Singh, Ajit, additional, Srinivasan, Sumithra Y., additional, Tambe, Prajakta, additional, Uthaman, Saji, additional, Varan, Gamze, additional, Varan, Cem, additional, Wasnik, Samiksha, additional, and Yordanov, Georgi, additional

Published
2019
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4. Chemo-biologic combinatorial drug delivery using folate receptor-targeted dendrimer nanoparticles for lung cancer treatment.

Author

Amreddy N, Babu A, Panneerselvam J, Srivastava A, Muralidharan R, Chen A, Zhao YD, Munshi A, and Ramesh R

Subjects
Antineoplastic Agents pharmacology, Apoptosis drug effects, Carcinoma, Non-Small-Cell Lung genetics, Carcinoma, Non-Small-Cell Lung pathology, Cell Proliferation drug effects, Combined Modality Therapy, ELAV-Like Protein 1 genetics, Humans, Lung Neoplasms genetics, Lung Neoplasms pathology, Lung Neoplasms therapy, Nanoparticles chemistry, RNA, Small Interfering genetics, Tumor Cells, Cultured, Carcinoma, Non-Small-Cell Lung therapy, Cisplatin pharmacology, Dendrimers chemistry, Drug Delivery Systems, ELAV-Like Protein 1 antagonists & inhibitors, Folate Receptor 1 metabolism, Nanoparticles administration & dosage
Abstract

Co-administration of functionally distinct anti-cancer agents has emerged as an efficient strategy in lung cancer treatment. However, a specially designed drug delivery system is required to co-encapsulate functionally different agents, such as a combination of siRNA and chemotherapy, for targeted delivery. We developed a folic acid (FA)-conjugated polyamidoamine dendrimer (Den)-based nanoparticle (NP) system for co-delivery of siRNA against HuR mRNA (HuR siRNA) and cis-diamine platinum (CDDP) to folate receptor-α (FRA) -overexpressing H1299 lung cancer cells. The co-delivery of HuR siRNA and CDDP using the FRA-targeted NP had a significantly greater therapeutic effect than did individual therapeutics. Further, the FRA-targeted NP exhibited improved cytotoxicity compared to non-targeted NP against lung cancer cells. Finally, the NP showed negligible toxicity towards normal MRC9 lung fibroblast cells. Thus, the present study demonstrates FRA-targeted Den nanoparticle system as a suitable carrier for targeted co-delivery of siRNA and chemotherapy agents in lung cancer cells., (Copyright © 2017 Elsevier Inc. All rights reserved.)

Published
2018
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