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The present study relies on the air quality evaluation during COVID-19 pandemic in Avellino, described in the last years and for several consecutive years, among the worst Italian cities in this context. The main purpose of this manuscript was to investigate the effects of quarantine and lockdown measures on air pollution. The concentrations of the main atmospheric pollutants (Carbon monoxide (CO), Ozone (O 3 ), Fine Particulate (PM 2.5 and PM 10 ), Benzene (C 6 H 6 ) and Nitrogen dioxide (NO 2 ) were recorded during the period January-December 2020 using two stationary monitoring stations (AV1 and AV2) of the Regional Environmental Protection Agency (ARPAC). During the lockdown period (March 9-May 18, 2020), results indicated significant reductions only in the levels of CO, benzene and NO 2 , while for PM 10 the limit of 50 μg m -3 was passed 8 times for AV1 and 13 times for AV2. The results showed the not predominant role of traffic on air quality in Avellino regards to PM levels and make it necessary a serious reflection about important and not extendable decisions to improve the air quality., (Copyright © 2021 Elsevier Inc. All rights reserved.)