6 results on '"Alison Elder"'
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2. Contributors
- Author
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Jan Aaseth, Peter Aggett, Antero Aitio, Agneta Åkesson, Maria Albin, Jan Alexander, Christian B.I. Andersen, Ole Andersen, Pietro Apostoli, Michael Aschner, Rowa Bakadlag, Lars Barregard, David C. Bellinger, Ingvar A. Bergdahl, Balazs Berlinger, Alfred Bernard, Carolina Bigert, Poul Bjerregaard, Robyn Blain, Lennart K. Blomqvist, Beatrice Bocca, Stephan Bose-O'Reilly, Karin Broberg, Ronald P. Brown, Esben Budtz-Jørgensen, Samuel W. Caito, Tiffany Carle, Chien-Jen Chen, Xiao Chen, Lung-Chi Chen, C.-H. Selene J. Chou, Mitchell D. Cohen, Max Costa, Giuseppe De Palma, Alison Elder, Carl-Gustaf Elinder, Bengt Fadeel, Obaid M. Faroon, Bruce A. Fowler, Hitomi Fujishiro, Silvia Fustinoni, Lars Gerhardsson, Philippe Grandjean, Per Gustavsson, Yolanda Hedberg, Seiichiro Himeno, Xi Huang, Per A. Hultman, Ivo Iavicoli, Taiyi Jin, Robert L. Jones, Hanna L. Karlsson, Larry S. Keith, Yangho Kim, Catherine B. Klein, Michael Kleinman, David Kotelchuck, Yukinori Kusaka, Philip J. Landrigan, Per E. Leffler, Veruscka Leso, Alex Heng Li, Dominique Lison, Shan Liu, Roberto G. Lucchini, Polina Maciejczyk, Koren K. Mann, Nikki Maples-Reynolds, Michael J. Maroney, Airton C. Martins, Mary S. Matsui, Daphne B. Moffett, Lisbeth Birk Møller, M. Moiz Mumtaz, Makiko Nakano, Benoit Nemery, Koji Nogawa, Gunnar F. Nordberg, Monica Nordberg, Angelica Ortiz, Agneta Oskarsson, Elena A. Ostrakhovitch, Cezary M. Pałczyński, Natalia Pawlas, Daniela Pelclova, Maria Pesonen, K. Michael Pollard, Lothar Rink, Flavia Ruggieri, Patricia Ruiz, Harold H. Sandstead, Tiina Santonen, Kazuhiro Sato, Hiroshi Satoh, Deepak Saxena, Greet Schoeters, Bengt Sjögren, Staffan Skerfving, Donald R. Smith, Dexter W. Sullivan, Daigo Sumi, Hong Sun, Hille Suojalehto, Akiyo Tanaka, Milton Tenenbein, George D. Thurston, Francisco A. Tomei Torres, Muhammet S. Toprak, Carolyn A. Tylenda, Julian F. Tyson, Tomohiro Umemura, Margaret H. Whittaker, Jana Wolf, Wenbo Yan, Robert A. Yokel, and Rudolfs K. Zalups
- Published
- 2022
- Full Text
- View/download PDF
3. Contributors
- Author
-
Jan Aaseth, Peter Aggett, Antero Aitio, Agneta Åkesson, Maria Albin, Jan Alexander, Christian B.I. Andersen, Ole Andersen, Pietro Apostoli, Michael Aschner, Rowa Bakadlag, Lars Barregard, David C. Bellinger, Ingvar A. Bergdahl, Balazs Berlinger, Alfred Bernard, Carolina Bigert, Poul Bjerregaard, Robyn Blain, Lennart K. Blomqvist, Beatrice Bocca, Stephan Bose-O'Reilly, Karin Broberg, Ronald P. Brown, Esben Budtz-Jørgensen, Samuel W. Caito, Tiffany Carle, Chien-Jen Chen, Xiao Chen, Lung-Chi Chen, C.-H. Selene J. Chou, Mitchell D. Cohen, Max Costa, Giuseppe De Palma, Alison Elder, Carl-Gustaf Elinder, Bengt Fadeel, Obaid M. Faroon, Bruce A. Fowler, Hitomi Fujishiro, Silvia Fustinoni, Lars Gerhardsson, Philippe Grandjean, Per Gustavsson, Yolanda Hedberg, Seiichiro Himeno, Xi Huang, Per A. Hultman, Ivo Iavicoli, Taiyi Jin, Robert L. Jones, Hanna L. Karlsson, Larry S. Keith, Yangho Kim, Catherine B. Klein, Michael Kleinman, David Kotelchuck, Yukinori Kusaka, Philip J. Landrigan, Per E. Leffler, Veruscka Leso, Alex Heng Li, Dominique Lison, Shan Liu, Roberto G. Lucchini, Polina Maciejczyk, Koren K. Mann, Nikki Maples-Reynolds, Michael J. Maroney, Airton C. Martins, Mary S. Matsui, Daphne B. Moffett, Lisbeth Birk Møller, M. Moiz Mumtaz, Makiko Nakano, Benoit Nemery, Koji Nogawa, Gunnar F. Nordberg, Monica Nordberg, Angelica Ortiz, Agneta Oskarsson, Elena A. Ostrakhovitch, Cezary M. Pałczyński, Natalia Pawlas, Daniela Pelclova, Maria Pesonen, K. Michael Pollard, Lothar Rink, Flavia Ruggieri, Patricia Ruiz, Harold H. Sandstead, Tiina Santonen, Kazuhiro Sato, Hiroshi Satoh, Deepak Saxena, Greet Schoeters, Bengt Sjögren, Staffan Skerfving, Donald R. Smith, Dexter W. Sullivan, Daigo Sumi, Hong Sun, Hille Suojalehto, Akiyo Tanaka, Milton Tenenbein, George D. Thurston, Francisco A. Tomei Torres, Muhammet S. Toprak, Carolyn A. Tylenda, Julian F. Tyson, Tomohiro Umemura, Margaret H. Whittaker, Jana Wolf, Wenbo Yan, Robert A. Yokel, and Rudolfs K. Zalups
- Published
- 2021
- Full Text
- View/download PDF
4. List of Contributors
- Author
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Jan Aaseth, Peter Aggett, Antero Aitio, Jan Alexander, Shegufta Ameer, Christian B.I. Andersen, Ole Andersen, Pietro Apostoli, Michael Aschner, Farida Louise Assem, Lars Barregård, David C. Bellinger, Ingvar A. Bergdahl, Maths Berlin, Balázs Berlinger, Alfred Bernard, Carolina Bigert, Poul Bjerregaard, Robyn Blain, Karin Broberg, Jason Brocato, Ronald P. Brown, Esben Budtz-Jørgensen, Samuel W. Caito, Simona Catalani, C.-J. Chen, C.-H. Selene, J. Chou, Max Costa, Todd Davidson, John W. Eaton, Alison Elder, Carl -Gustaf Elinder, Dag G. Ellingsen, Hisham A. El-Masri, Karin Engström, Bengt Fadeel, Obaid M. Faroon, Bruce A. Fowler, Silvia Fustinoni, Lars Gerhardsson, Philippe Grandjean, Per Gustavsson, James S. Holler, Per Hultman, Ivo Iavicoli, Anders Iregren, Marek Jakubowski, Taiyi Jin, Robert L. Jones, Hanna L. Karlsson, George Kazantzis, Qindong Ke, Larry S. Keith, Mirja Kiilunen, Yangho Kim, Catherine Klein, Michael Kleinman, David Kotelchuck, Yukinori Kusaka, Philip J. Landrigan, Sverre Langård, Freda Laulicht, Per E. Leffler, Veruscka Leso, Dominique Lison, Roberto G. Lucchini, Nikki Maples-Reynolds, Daphne B. Moffett, Lisbeth Birk Møller, Johan Montelius, Moiz M. Mumtaz, Koji Nogawa, Gunnar F. Nordberg, Monica Nordberg, Agneta Oskarsson, Elena A. Ostrakhovich, Cezary PałczyŃski, K. Michael Pollard, Prem Ponka, Candace M. Prusiewicz, Patricia Ruiz, Harold H. Sandstead, Tiina Santonen, Marko ŠariĆ, Kazuhiro Sato, Hiroshi Satoh, Mary J. Sexton, Bengt Sjögren, Staffan Skerfving, Donald R. Smith, Dexter W. Sullivan, Jonas Tallkvist, Milton Tenenbein, Muhammet S. Toprak, Carolyn Tylenda, Tomohiro Umemura, Richard P. Wedeen, Robert A. Yokel, and Rudolfs K. Zalups
- Published
- 2015
- Full Text
- View/download PDF
5. List of Contributors
- Author
-
Jan Aaseth, Peter Aggett, Antero Aitio, Jan Alexander, Shegufta Ameer, Christian B.I. Andersen, Ole Andersen, Pietro Apostoli, Michael Aschner, Farida Louise Assem, Lars Barregård, David C. Bellinger, Ingvar A. Bergdahl, Maths Berlin, Balázs Berlinger, Alfred Bernard, Carolina Bigert, Poul Bjerregaard, Robyn Blain, Karin Broberg, Jason Brocato, Ronald P. Brown, Esben Budtz-Jørgensen, Samuel W. Caito, Simona Catalani, C.-J. Chen, C.-H. Selene, J. Chou, Max Costa, Todd Davidson, John W. Eaton, Alison Elder, Carl -Gustaf Elinder, Dag G. Ellingsen, Hisham A. El-Masri, Karin Engström, Bengt Fadeel, Obaid M. Faroon, Bruce A. Fowler, Silvia Fustinoni, Lars Gerhardsson, Philippe Grandjean, Per Gustavsson, James S. Holler, Per Hultman, Ivo Iavicoli, Anders Iregren, Marek Jakubowski, Taiyi Jin, Robert L. Jones, Hanna L. Karlsson, George Kazantzis, Qindong Ke, Larry S. Keith, Mirja Kiilunen, Yangho Kim, Catherine Klein, Michael Kleinman, David Kotelchuck, Yukinori Kusaka, Philip J. Landrigan, Sverre Langård, Freda Laulicht, Per E. Leffler, Veruscka Leso, Dominique Lison, Roberto G. Lucchini, Nikki Maples-Reynolds, Daphne B. Moffett, Lisbeth Birk Møller, Johan Montelius, Moiz M. Mumtaz, Koji Nogawa, Gunnar F. Nordberg, Monica Nordberg, Agneta Oskarsson, Elena A. Ostrakhovich, Cezary PałczyŃski, K. Michael Pollard, Prem Ponka, Candace M. Prusiewicz, Patricia Ruiz, Harold H. Sandstead, Tiina Santonen, Marko ŠariĆ, Kazuhiro Sato, Hiroshi Satoh, Mary J. Sexton, Bengt Sjögren, Staffan Skerfving, Donald R. Smith, Dexter W. Sullivan, Jonas Tallkvist, Milton Tenenbein, Muhammet S. Toprak, Carolyn Tylenda, Tomohiro Umemura, Richard P. Wedeen, Robert A. Yokel, and Rudolfs K. Zalups
- Published
- 2015
- Full Text
- View/download PDF
6. Routes of Exposure, Dose, and Toxicokinetics of Metals∗∗This chapter is based on the chapter Routes of Exposure, Dose, and Metabolism of Metals by W.S. Beckett, G.F. Nordberg, and T.W. Clarkson in the third edition of this handbook
- Author
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Gunnar F. Nordberg, Michael T. Kleinman, and Alison Elder
- Subjects
Absorption (pharmacology) ,Cadmium ,chemistry.chemical_element ,Metal ,Excretion ,chemistry.chemical_compound ,chemistry ,visual_art ,Environmental chemistry ,Ultrafine particle ,visual_art.visual_art_medium ,Metallothionein ,Toxicokinetics ,Sulfate - Abstract
The chapter first describes the main sources of metal exposure through air, food, and water, but also points to unusual sources such as medical implants. Special attention is given to the processes of lung deposition and clearance of inhaled gases, vapors, and particulates, including ultrafine particles. In contrast to the extensive studies on the lung, the absorption of metal in the gastrointestinal tract is less well understood. A summary diagram shows the contribution of all the absorption processes to the total body burden. Since the publication of the third edition, new information has become available on the mechanisms of transport and distribution of metals in the body. In particular, it has been shown that several metals can cross cell membranes via specific carriers and ion channels intended for endogenous substrates. One well-documented example is the chromate oxyanion that is structurally similar to the sulfate anion and thereby gains entrance into the cell via the sulfate carrier. Attention is also given to the transport of ultrafine particles and nanoparticles across barrier epithelia. The fecal excretion of several metals occurs as the end result of extensive enterohepatic recirculation. In the case of certain organometallic species, gut microflora may play a critical role in converting the metal to an inorganic form, which is excreted in the feces. Renal accumulation and excretion of metals has also received considerable attention. Renal accumulation of cadmium in the form of its complex with the small molecular weight protein, metallothionein, remains one of the best-documented mechanisms. Toxicokinetic models continue to be useful in providing a quantitative description of the overall body turnover of metals. They can be useful in establishing dose-response relationships where, for example, the range of half-times of elimination of a metal can contribute to the overall variance in the dose-response relationship. In addition to the observation-based models, pharmacokinetic models can be developed based on a priori physiological and mechanistic considerations. The chapter concludes with a consideration of indicator media that best reflect the dose to the critical organ.
- Published
- 2015
- Full Text
- View/download PDF
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