1. Clinical practice versus guidelines for the screening of cystic fibrosis-related diabetes: A French survey from the 47 centers
- Author
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Laurence Weiss, Olivia Ronsin, Quitterie Reynaud, Michel Abely, Laurent Mely, Pierre-Régis Burgel, Jacques Beltrand, and Laurence Kessler
- Subjects
Cystic fibrosis ,Diabetes ,Screening ,OGTT ,Continuous glucose monitoring ,Diseases of the endocrine glands. Clinical endocrinology ,RC648-665 - Abstract
This study aimed to analyze clinical practices concerning cystic fibrosis-related diabetes (CFRD) screening in France. A web-based questionnaire was distributed between December 1, 2020 and January 31, 2021 among 47 cystic fibrosis centers including pediatric, adult, and mixed units. In accordance with guidelines, 92.8% of CF centers performed annual oral glucose tolerance tests (OGTT). Overall, 86.3% of CF centers performed 1- and 2-hour blood glucose determinations following OGTT. The OGTT was conducted before 10 years of age in 73% of pediatric centers. Continuous glucose monitoring (CGM) and laboratory glycated hemoglobin were employed for CFRD screening in 86.5% and 50% of centers, respectively. CGM was carried out in 69% of centers after glucose tolerance abnormalities had been detected in OGTT. Most CF centers used OGTT and CGM for CFRD screening. Studies are required to assess CGM usefulness as a validated tool in CFRD screening.
- Published
- 2022
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