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Objective: The aim of this study was to assess changes in the ages at which the main stages of reproductive life, including first sexual intercourse in particular, occur in Guadeloupe (French West Indies)., Patients and Methods: We conducted a transverse study of three generations of men and women over the age of 20 years. We recorded age at first intercourse and at first child for all subjects, plus age at menarche, at first pregnancy and at menopause for the women., Results: We collected information for 803 women and 169 men. For women, median age at menarche and at first intercourse had decreased significantly, reaching 12 and 17 years, respectively. The risk of first intercourse occurring before the median age was linked to the earliness of menarche. Age at first pregnancy, at menopause for women and at first intercourse for men remained roughly stable. A non-significant trend towards increasing age at the birth of the first child was observed in both sexes., Discussion and Conclusion: Age indicators for the main stages of reproductive life in Guadeloupe follow the trends reported in most Western countries, including mainland France. However, most of the ages recorded for particular stages are below those in mainland France. The link between age at menarche and sexual precocity may justify targeted awareness programs., (Copyright © 2013 Elsevier Masson SAS. All rights reserved.)