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Background: Nutcracker Syndrome (NCS) is a rarely encountered clinical condition. In NCS, due to the compression of the left renal vein between aorta and superior mesenteric artery, outflow of the left renal vein is impaired. It may occur with the symptoms like hematuria, proteinuria, pain on the left lumber, lower abdomen, varicocele and pelvic congestion or asymptomatic. In suspected cases, the diagnosis can be established by the radiological imaging. Case Presentation: In this case report, a 31 year old female who was referred to a live kidney donor diagnosed with NCS during preoperative evaluation is described. Transplantation process and post-transplantation course have been discussed according to literature. This case report is unique due to being the first report describing allogeneic kidney transplantation performed from a donor with NCS. Conclusion: In nutcracker syndrome, surgical treatment is recommended for the patients with serious symptoms. Surgical interventions and stenting are treatment modalities and this article suggests a new approach. It may be meaningful in terms of reporting the first successful allogeneic transplantation performed from a donor with NCS.