1. [Caenorhabditis elegans as a model organism for aging: relevance, limitations and future].
- Author
-
Litke R, Boulanger É, and Fradin C
- Subjects
- Aging genetics, Animals, Humans, Longevity genetics, Aging pathology, Caenorhabditis elegans physiology, Models, Animal
- Abstract
Aging is a physiological and complex process associated with increasing age of living organisms. Simple model organisms have brought significant advances in our understanding of the aging process. Caenorhabditis elegans, a nematode originally used to establish the genetic and molecular basis of development, has become one of the leading model organisms for research on aging. This invertebrate has allowed identifying a connection between cellular signaling pathways and longevity. Although C. elegans is not suitable for analysis of the complete process of human aging, it remains a model of choice to analyze specific aging mechanisms and phenotypes., (© 2018 médecine/sciences – Inserm.)
- Published
- 2018
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