1. Clinical features and outcomes between African American and Caucasian patients with Takotsubo Syndrome
- Author
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Krishna Ravindra, Tamas S Gal, Curtis Maehara, Dinesh Kadariya, Lori Keyser-Marcus, Megan Dell, Edoardo Bressi, Peter Westman, Marco Giuseppe Del Buono, Liangsuo Ma, Juan Guido Chiabrando, Antonio Abbate, Larry Keen, Jessie van Wezenbeek, and F. Gerard Moeller
- Subjects
medicine.medical_specialty ,Acute coronary syndrome ,education.field_of_study ,Ejection fraction ,business.industry ,Population ,medicine.disease ,Logistic regression ,Article ,White People ,Black or African American ,Angina ,Takotsubo Cardiomyopathy ,Heart failure ,Internal medicine ,medicine ,Humans ,Acute Coronary Syndrome ,Cardiology and Cardiovascular Medicine ,Complication ,business ,education ,Stroke ,Retrospective Studies - Abstract
BACKGROUND. Takotsubo syndrome (TS) is an acute, reversible form of heart failure, often mimicking an acute coronary syndrome (ACS). Data regarding racial differences in TS are inconsistent. The aim is to assess clinical features associated with unfavorable in-hospital outcomes between African American (AA) and Caucasian (CAU) patients. METHODS. A retrospective electronic health record query identified 44 AA patients and 110 CAU patients with a diagnosis of TS. Our primary outcome was a composite of death, stroke, and cardiogenic shock during hospitalization. Variables associated with an increased risk of the primary composite outcomes were included in a logistic regression model. RESULTS. Compared to CAU patients, AA patients were a more comorbid population, and presented a higher prevalence of history of illicit drug use (27.3% vs 13.6% p=0.044). There were no significant differences regarding in-hospital complication rates between AA and CAU patients. In the logistic regression model, infection was associated with greater risk of developing the primary outcome in AA patients (OR=7.26 95% CI [1.22–43.17], p=0.029), whereas angina was a protective factor (OR=0.11 95% CI [0.02–0.65], p=0.015). In CAU patients, severely depressed ejection fraction and worse peak creatinine during hospitalization increased risk of developing the primary outcome (OR=5.88 95% CI [2.01–17.17], p
- Published
- 2021