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Background: Police institutions often use Occupational Physical Ability Tests (OPATs) as a measure of occupational performance. These tests are utilized to mimic the daily and essential tasks performed by the police officers, but few are performed with load carriage (LC). The purpose of this study was to examine the physical performance predictors of an OPAT performed without (NPPE) and with (WPPE) LC., Methods: Thirteen federal highway police officers (age: 36.8±3.7 years, body mass: 89±10.7 kg, height: 180±5.6 cm) volunteered to complete a battery of physical fitness tests (aerobic power and capacity, muscular endurance, lower limb power, upper limb strength, agility and anaerobic power) and anthropometrics. Occupational performance was measured by the total OPAT time consisting of 7 sequential police tasks. All subjects randomly completed the tests on both LC conditions., Results: Agility (P<0.01), lower limb power and height (P<0.05) were significantly related to performance in the NPPE OPAT. In the WPPE condition, aerobic power (absolute and relative) (P<0.01), lower limb power and agility (P<0.05). The best predictors for OPAT performance were agility (R2=0.45, P<0.01) in the NPPE condition, as well as relative aerobic power, upper limb strength and agility in the WPPE condition (R2=0.81, P<0.01)., Conclusions: Different conditions of LC have distinct occupational performance predictors. Thus, considering LC, physical exercise programs aimed at improving police occupational performance should aim at improving agility, upper limb strength and aerobic fitness.

The antibronchospastic value of the triple association adrenaline (1) + atropine (0,3) + papaverine (3) has been documented experimentally. Comparative investigations have been carried out with isoprenaline, metaproterenol, terbutaline and salbutamol. Toxicological and pharmacodynamic studies were done in the cardiovascular system and in vitro on certain muscles.

In experiments at cardiovascular system level, acebutolol was found to possess beta-adrenolytic activity of cardioselective type associated with intrinsic beta-adrenergic, antiarrhythmic and anti-hypertensive activity. It was well tolerated systemically.