1. [Pymadine, a new type of non-depolarizing muscle-relaxant antagonist].
- Author
-
Stoianov E, Marinova M, and Stîrbova M
- Subjects
- 4-Aminopyridine, Curare antagonists & inhibitors, Humans, Aminopyridines administration & dosage, Central Nervous System Stimulants therapeutic use, Cholinesterase Inhibitors administration & dosage, Neuromuscular Depolarizing Agents administration & dosage, Postoperative Care
- Abstract
The paper presents the author's experience in post-anesthetic decurarization with a new antagonist of competitive curare. Presented for the first time in 1970, 4-amino-pyridine was found o tbe a substance with a different mode of action than that of reversible inhibitors of cholinesterase, without parasympaticomimetic effects, and without untoward effects on the cardio-circulatory function. It also has a central analeptic effect. This is why the authors consider the new drug as a powerful means for reversing the competitive neuromuscular blockage.
- Published
- 1981