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The winter cold stress of dairy cows has become one of the important problems affecting the healthy development of animal husbandry. Cold stress will lead to the decrease of feed intake, milk yield and reproductive performance of dairy cows, and seriously harm the economic benefits of dairy farmers. Inner Mongolia is located in a cold region, where animals are in a cold environment for a long time, and the impact of cold stress is more common. In order to more specifically understand the effects of cold stress on the production performance of dairy cows, the paper reviews the effects of cold stress on the behavior, milk yield, neuroendocrine, biochemical indexes, immune, antioxidant function, intestinal flora and other aspects of dairy cows, and summarizes the effective prevention and control measures to prevent cold stress of dairy cows, to provide reference for further research on the prevention and relief of cold stress in dairy cows. [ABSTRACT FROM AUTHOR]