1. Acne, the microbiome and innate immunity
- Author
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Pierre Wolkenstein, Geraldine Robert, Marc Feuiolley, Marius-Anton Ionescu, Jérémy Enault, and Luc Lefeuvre
- Subjects
Innate immune system ,business.industry ,Applied Mathematics ,General Mathematics ,Immunology ,Medicine ,Microbiome ,business ,medicine.disease ,Acne - Abstract
In the laste years several articles focalized on human microbioma - the microorganisms from skin, mucosae, bowel - and on its role in chronic inflammatory diseases of the skin as acne, rosacea, atopic dermatitis, seborrheic dermatitis. In this article the authors present an update on particular acne skin’s microbioma, on innate immunity in acne and new physiopathology mecanisms described in inflammatory process in acne, and at the end we present in vitro, ex vivo and in vivo studies on the microbioma modulation and microbiofilm of pathogenic ribotypes of P. acnes leading to a significant improvement of acne in a series of 74 acne patients. more...
- Published
- 2016
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