1. The association between the serum level of vitamin D and ischemic heart disease: a study from Jordan
- Author
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Yousef Khader, Karem H. Alzoubi, Enas S. Alsatari, Mohamad I Jarrah, Mo'ath F Bataineh, Nizar M. Mhaidat, and Nasr Alrabadi
- Subjects
Male ,medicine.medical_specialty ,Endocrinology, Diabetes and Metabolism ,030209 endocrinology & metabolism ,Coronary Artery Disease ,Disease ,030204 cardiovascular system & hematology ,Coronary Restenosis ,03 medical and health sciences ,Percutaneous Coronary Intervention ,0302 clinical medicine ,Risk Factors ,Diabetes mellitus ,Internal medicine ,Prevalence ,medicine ,Vitamin D and neurology ,Humans ,Pharmacology (medical) ,Vitamin D ,Cross-Over Studies ,Jordan ,Unstable angina ,business.industry ,Incidence ,Incidence (epidemiology) ,Coronary Stenosis ,Public Health, Environmental and Occupational Health ,Hematology ,General Medicine ,Vitamin D Deficiency ,medicine.disease ,Vascular Health and Risk Management ,Treatment Outcome ,Case-Control Studies ,Cardiology ,Female ,Stents ,Cardiology and Cardiovascular Medicine ,business ,Ischemic heart ,Body mass index ,Biomarkers ,Dyslipidemia - Abstract
Mohamad I Jarrah,1 Nizar M Mhaidat,2 Karem H Alzoubi,2 Nasr Alrabadi,3 Enas Alsatari,2 Yousef Khader,4 Moath F Bataineh5 1Department of Internal Medicine, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan; 2Department of Clinical Pharmacy, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid, Jordan; 3Department of Pharmacology, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan; 4Department of Public Health and Community Medicine, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan; 5Department of Sport Rehabilitation, Faculty of Physical Education and Sport Sciences, Hashemite University, Zarqa, Jordan Background: Decreased levels of vitamin D were associated with increased risk of multiple diseases, including cardiovascular diseases. However, there seem to be some discrepancies among the results obtained from different studies. The aim of the present study was to explore the importance of having sufficient serum levels of vitamin D in reducing the incidence and the progression of coronary artery stenosis and ischemic heart disease (IHD). Methods: Serum levels of vitamin D were measured using radioimmunoassay in 186 Jordanian patients who underwent investigative coronary catheterization. Of these patients, 133 were suffering from coronary artery stenosis. The association between vitamin D levels, coronary stenosis and many risk factors was determined using SPSS software. Results and conclusions: Interestingly, the current results did not show an association between vitamin D abnormalities and the incidence or the reoccurrence of coronary artery stenosis. Moreover, significant differences were detected in the prevalence of vitamin D abnormalities based on the patient’s gender, and there was a significant association between vitamin D abnormalities and both body mass index and dyslipidemia. However, current results did not show any significant association with other risk factors for IHD. For instance, no association was found with smoking, hypertension, diabetes mellitus, stable and unstable angina or with acute recent myocardial infarction. Keywords: vitamin D, ischemic heart disease, IHD, coronary artery stenosis, cardiovascular system
- Published
- 2018