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Your search keyword '"Miłkowska-Dymanowska, Joanna"' showing total 6 results
Start Over Author "Miłkowska-Dymanowska, Joanna" Publisher dove medical press ltd
6 results on '"Miłkowska-Dymanowska, Joanna"'

4. Geroprotectors as a therapeutic strategy for COPD - where are we now?

Author

Miłkowska-Dymanowska, Joanna, Białas, Adam J., Makowska, Joanna, Wardzynska, Aleksandra, Górski, Paweł, and Piotrowski, Wojciech J.

Subjects
OBSTRUCTIVE lung disease treatment, QUALITY of life, OXIDATIVE stress
Abstract

Although current therapies in chronic obstructive pulmonary disease (COPD) improve the quality of life, they do not satisfactorily reduce disease progression or mortality. There are still many gaps in knowledge about the cellular, molecular, and genetic mechanisms contributing to pathobiology of this disease. However, increasing evidence suggests that accelerated aging, chronic systemic inflammation, and oxidative stress play major roles in pathogenesis in COPD, thus opening new opportunities in therapy. Therefore, the aim of our review was to describe and discuss some of the most widely used therapeutics that affect the root cause of aging and oxidative stress (metformin, melatonin, sirolimus, statins, vitamin D, and testosterone) in context of COPD therapy. [ABSTRACT FROM AUTHOR]

Published
2017
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