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Background: A comprehensive literature review suggests that self-esteem seems to be contingent on being satisfied in various domains of life. Although there are multiple studies that have addressed the direct relationship between both variables, there is still little known about the psychological mechanisms that underlie this association. Since self-presentation is an important process in young adulthood, the main goal of the present study was to consider self-promotion and self-deprecation as potential mediators between life satisfaction and self-esteem., Participants Methods and Data Collection: The study included 328 young adults aged between 18 and 35. Most of them were women (74.1%). The data were collected in Poland through an anonymous self-administered battery of questionnaires on the Internet platform. The participants completed the Satisfaction with Life Scale, the Rosenberg Self-Esteem Scale, and the Self-Presentation Style Questionnaire., Results: A high and positive correlation coefficient was obtained between self-esteem and life satisfaction ( r = 0.73; p < 0.001). The level of self-esteem correlated positively with the style of self-promotion ( r = 0.46; p < 0.001) and negatively with the style of self-deprecation ( r = -0.63; p < 0.001). Similarly, life satisfaction was positively associated with self-promotion ( r = 0.37; p < 0.001) and negatively with self-depreciation ( r = -0.42; p < 0.001). Moreover, both self-promotion (β = 0.67; p < 0.001) and self-deprecation (β = 0.58; p < 0.001) acted as mediators between life satisfaction and self-esteem., Conclusion: The present study increases our knowledge about the mediatory role of self-promotion and self-deprecation. An overall sense of satisfaction with one's own life can lead to higher self-esteem when young people are aware of their strengths and talents. Likewise, lower life satisfaction can elicit less positive self-esteem when people tend to undervalue their capabilities., Competing Interests: The authors report no conflicts of interest in this work., (© 2021 Szcześniak et al.)

Introduction: Increasing bacteria resistance to antibiotics is a major problem of healthcare system. There is a need for solutions that broaden the spectrum of bactericidal agents improving the efficacy of commonly used antibiotics. One of the promising directions of search are silver nanoparticles (obtained by different methods and displaying diversified physical and chemical properties), and their combination with antibiotics., Purpose: In this study, we tested the role of reactive oxygen species in the mechanism of synergistic antibacterial activity of gentamicin and Tween-stabilized silver nanoparticles against gentamicin-resistant clinical strains of Staphylococcus epidermidis ., Methods: Synergistic bactericidal activity of gentamicin and silver nanoparticles stabilized with non-ionic detergent (Tween 80) was tested by the checkerboard titration method on microtiter plates. Detection of reactive oxygen species was based on the chemiluminescence of luminol., Results: Hydrophilic non-ionic surface functionalization of silver nanoparticles enabled the existence of non-aggregated active nanoparticles in a complex bacterial culture medium. Tween-stabilized silver nanoparticles in combination with gentamicin exhibited bactericidal activity against multidrug-resistant biofilm forming clinical strains of Staphylococcus epidermidis . A synergistic effect significantly decreased the minimal inhibitory concentration of gentamicin (the antibiotic with numerous undesirable effects). Gentamicin significantly enhanced the generation of reactive oxygen species by silver nanoparticles., Conclusion: Generation of reactive oxygen species by Tween-coated metallic silver nanoparticles was significantly enhanced by gentamicin, confirming the hypothesis of oxidative-associated mechanism of the synergistic antibacterial effect of the gentamicin-silver nanoparticles complex., Competing Interests: The authors report no conflicts of interest in this work., (© 2020 Mazur et al.)