1. Staging laparoscopy and Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC) for peritoneal metastasis: safe access to the abdomen
- Author
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Giorgi Nadiradze, Sven A. Lang, Rami Archid, Torben Glatz, and Philipp Horvath
- Subjects
Peritoneal metastasis ,medicine.medical_specialty ,medicine.medical_treatment ,laparoscopy ,PIPAC ,chemotherapy ,03 medical and health sciences ,0302 clinical medicine ,Internal Medicine ,Medicine ,Staging laparoscopy ,Toxic emphysema ,Laparoscopy ,Chemotherapy ,medicine.diagnostic_test ,business.industry ,Fascia ,Surgery ,Palliative Therapy ,medicine.anatomical_structure ,030220 oncology & carcinogenesis ,peritoneal metastasis ,Abdomen ,030211 gastroenterology & hepatology ,abdominal access ,business ,Research Article - Abstract
Background Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC) is an innovative drug delivery technique. Most common indication is palliative therapy of peritoneal metastasis of gastrointestinal and gynecological origin in the salvage situation. Access to the abdomen is the critical step of the procedure, since most patients had previous surgery. Potential pitfalls include non-access because of adhesions, bowel access lesions and postoperative subcutaneous toxic emphysema. Methods We propose a technique, the “finger-access technique” that might prevent largely these pitfalls. A minilaparotomy of 3 cm is performed in the midline, a finger introduced into the abdomen and a 5-mm double-balloon trocar (no Hasson trocar) is placed under finger protection at some distance of the first incision. The fascia of the minilaparotomy, not the skin, is then closed. The abdomen is insufflated with CO2 and tightness is controlled with saline solution in the minilaparotomy. A second 10–12 mm trocar is then introduced under videoscopic control. The first trocar is then visualized through the second one to exclude a bowel lesion during first access. Results and conclusions In our hands, this access technique has shown to be safe and effective.
- Published
- 2019