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Start Over Author "Eng, Melissa" Publisher de gruyter
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1. Multicenter dose-escalation Phase I trial of mitomycin C pressurized intraperitoneal aerosolized chemotherapy in combination with systemic chemotherapy for appendiceal and colorectal peritoneal metastases: rationale and design

Author

Raoof Mustafa, Sullivan Kevin M., Frankel Paul H., Fakih Marwan, Synold Timothy W., Lim Dean, Woo Yanghee, Paz Isaac Benjamin, Fong Yuman, Thomas Rebecca Meera, Chang Sue, Eng Melissa, Tinsley Raechelle, Whelan Richard L., Deperalta Danielle, Reymond Marc A., Jones Jeremy, Merchea Amit, and Dellinger Thanh H.

Subjects
appendiceal cancer, colorectal cancer (crc), mitomycin c (mmc), peritoneal metastasis (pm), phase i study, pressurized intraperitoneal aerosolized chemotherapy (pipac), Medicine, Specialties of internal medicine, RC581-951
Abstract

Peritoneal metastasis (PM) from appendiceal cancer or colorectal cancer (CRC) has significant morbidity and limited survival. Pressurized intraperitoneal aerosolized chemotherapy (PIPAC) is a minimally invasive approach to treat PM. We aim to conduct a dose-escalation trial of mitomycin C (MMC)-PIPAC combined with systemic chemotherapy (FOLFIRI) in patients with PM from appendiceal cancer or CRC.

Published
2022
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