1. EGCG modulates PKD1 and ferroptosis to promote recovery in ST rats
- Author
-
Wang Jianjun, Chen Ying, Chen Long, Duan Yanzhi, Kuang Xuejun, Peng Zhao, Li Conghui, Li Yuanhao, Xiao Yang, Jin Hao, Tan Quandan, Zhang Shaofeng, Zhu Bopei, and Tang Yinjuan
- Subjects
spinal cord injury ,(−)-epigallocatechin-3-gallate ,cerebellar granule neurons ,ferroptosis ,oxidative stress ,Neurosciences. Biological psychiatry. Neuropsychiatry ,RC321-571 - Abstract
Spinal cord injury (SCI) causes devastating loss of function and neuronal death without effective treatment. (−)-Epigallocatechin-3-gallate (EGCG) has antioxidant properties and plays an essential role in the nervous system. However, the underlying mechanism by which EGCG promotes neuronal survival and functional recovery in complete spinal cord transection (ST) remains unclear.
- Published
- 2020
- Full Text
- View/download PDF