1. High preoperative Glasgow prognostic score is a negative prognostic factor for patients with endometrial carcinoma
- Author
-
Hitomi Yamashita, Kohei Nakamura, Takayoshi Komatsu-Fujii, Toshiko Minamoto, Masako Ishikawa, Kaori Sanuki, Ruriko Ono, Kentaro Nakayama, Tomoka Ishibashi, Satoru Kyo, and Hiroki Sasamori
- Subjects
0301 basic medicine ,Oncology ,Cancer Research ,medicine.medical_specialty ,Multivariate analysis ,overall survival ,endometrial carcinoma ,Glasgow prognostic score ,03 medical and health sciences ,0302 clinical medicine ,Carcinoembryonic antigen ,Internal medicine ,Carcinoma ,medicine ,Progression-free survival ,Stage (cooking) ,Survival analysis ,Predictive marker ,biology ,business.industry ,Cancer ,Articles ,medicine.disease ,3. Good health ,030104 developmental biology ,030220 oncology & carcinogenesis ,biology.protein ,business ,progression-free survival - Abstract
The aim of the present study was to determine the prognostic value of the Glasgow prognostic score (GPS) in endometrial carcinoma (EC). Patients with EC who underwent surgery at the Shimane University Hospital between January 1997 and December 2013 were enrolled (n=118). The associations between pretreatment GPS and clinical parameters, including age, histological type, International Federation of Gynecology and Obstetrics stage, tumor grade, carbohydrate antigen 19-9 and carcinoembryonic antigen levels, progression-free survival (PFS), and overall survival (OS), were investigated. Survival analysis was performed with the Kaplan-Meier method, and prognostic factors were evaluated with Cox's proportional hazards regression model. A high pretreatment GPS was associated with advanced clinical stage, histological type and tumor grade (P
- Published
- 2018