1. Experimentální model intrakraniálních aneuryzmat.
- Author
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Hundža Stratilová, M., Kárová, K., Machová Urdzíková, L., Jendelová, P., Koblížek, M., Sameš, M., Zámečník, J., and Hejčl, A.
- Subjects
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INTRACRANIAL aneurysms , *LABORATORY mice , *ANIMAL disease models , *ANEURYSMS , *PILOT projects , *INTRACRANIAL aneurysm ruptures - Abstract
Rupture of an intracranial aneurysm represents a life-threatening condition with a still high mortality and morbidity. The pathogenesis of aneurysm development and eventual aneurysm rupture are still shrouded in mystery, representing a great field of research opportunities for scientists. Despite certain limitations, experimental models of intracranial aneurysms have their invaluable place. The review article summarizes the published results of current experimental rodent-focused models, their advantages, as well as limitations. At the same time, it introduces the reader to the results of our pilot study of an experimental laboratory mice model. [ABSTRACT FROM AUTHOR]
- Published
- 2024