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ALPPS (Associated Liver Partition and Portal Vein Ligation for Staged Hepatectomy) is an innovative surgical procedure which was presented for the first time in 2012, and in last two years it has become widely accepted by hepatobiliary surgeons and cosequently three ALPPS procedures have been performed at our institution so far. Considering that ALPPS is a relatively new method, indicated only in carefully selected patients, we still expect studies on larger number of patients, but according to last results ALPPS has proved to be a very successful surgical method which allows resectability of tumors that were considered irresectable, by promoting surprisingly fast and intensive hypertrophy of future liver remnant., {"references":["Schnitzbauer A, Lang S A, Fichtner-Feigl, et al. In situ split with portal vein ligation induces rapid left lateral lobe hypertrophy enabling two-staged extended right hepatic resection. Berlin: Oral Presentation; 2010. p. 35.","Bertens KA, Hawel J, Lung K, Buac S, Pineda-Solis K, Hernandez-Alejandro R. ALPPS: challenging the concept of unresectability – a systematic review. Int J Surg 2015 Jan;13: 280–287.","Alvarez FA, Ardiles V, de Santibanes M, Pekolj J, de Santibanes E. Associating liver partition and portal vein ligation for staged hepatectomy offers high oncological feasibility with adequate patient safety: a prospective study at a single center. Ann Surg 2015 Apr;261(4): 723–732.","Torres OJ, Moraes-Junior JM, Lima e Lima NC, Moraes AM. Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS): a new approach in liver resections. Arquivos brasileiros de cirurgia digestiva: ABCD. Brazilian archives of digestive surgery 2012;25(4): 290–2. Epub 2013/02/16.","Tschuor C, Croome KP, Sergeant G, et al. Salvage parenchymal liver transection for patients with insufficient volume increase after portal vein occlusion – an extension of the ALPPS approach. European journal of surgical oncology: the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 2013;39(11): 1230–1235.","Vyas SJ, Davies N, Grant L, et al. Failure of portal venous embolization. ALPPS as salvage enabling successful resection of bilobar liver metastases. J Gastrointest Cancer 2014.","Hernandez-Alejandro R, Bertens KA, Pineda-Solis K, Croome KP. Can we improve the morbidity http://www.kbc-zagreb.hr/and mortality associated with the associating liver partition with portal vein ligation for staged hepatectomy (ALPPS) procedure in the management of colorectal liver metastases? Surgery. 2014. Epub 2014/10/06.","Nadalin S, Capobianco I, Li J, Girotti P, Königsrainer I, Königsrainer A. Indications and limits for associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) lessons learned from 15 cases at a single centre. Z Gastroenterol 2014;52(1): 35–42.","Schadde E, Ardiles V, Slankamenac K, et al. ALPPS offers a better chance of complete resection in patients with primarily unresectable liver tumors compared with conventional-staged hepatectomies: Results of a multicenter analysis. World J Surg. 2014;38(6): 1510–1519.","Schadde E, Ardiles V, Robles-Campos R, et al. Early Survival and Safety of ALPPS: First Report of the International ALPPS Registry. Ann Surg 2014;260(5): 829–838.","Herman P, Krüger JAP, Perini MV, Coelho FF, Cecconello I. High Mortality Rates After ALPPS: the devil is the indication. J Gastrointest Cancer 2015."]}