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This book covers the entire field of research in the area of minor tranquillizers and its application to current clinical practice in the treatment of anxiety and insomnia. These drugs are principally the benzodiazepines and related drugs with a similar mechanism of action, such as zolpidem and zopiclone. The molecular mechanism of action of benzodiazepines is described, focussing on the interaction of these drugs with the different isoform of the GABAA^O >receptor, and the consequences of this for brain function. Recent advances in this knowledge have provided a framework for defining the physiochemical nature of the interaction between such drugs and their receptor protein, and thus pave the way for the design of new anxiolytic and hypnotic drugs. The animal models available for evaluating the potential of such new therapeutic agents in the treatment of anxiety and insomnia are discussed. Furthermore, understanding of the physiological regulation of the GABAA receptor may provide insights into the aetiopathology of these diseases. The clinical use of benzodiazepines and related drugs in the treatment of anxiety, insomnia, epilepsy and as anaesthetics are explored. The advantages and limitations of such treatments are discussed, and the impact of drugs evaluated. A chapter is devoted to the issue of independence, the clinical pertinence of tolerence and dependence, and evaluates treatment options that may minimise the risk of dependence.

Post Traumatic Stress Disorder can be one of the most disabling of all the anxiety disorders and is frequently misdiagnosed and ineffectively treated It is also an area in which there have been recent major advances This book sets out to solve this problem, presenting doctors with practical guidance and at the same time a state-of-the-art summary o

Life Care Planning and Case Management Handbook, Second Edition brings together the many concepts, beliefs, and procedures regarding life care plans into one state-of-the-art publication. This second edition of a bestseller is focused on prioritizing and managing the spectrum of services for people with serious medical problems and their families.<

In clinical practice, complex patients with comorbidity of mood and anxiety disorders are arguably the norm. These volumes focus on this area, providing up-to-date reviews of the conceptual issues that confront the clinician when evaluating these patients Concise and easy-to-read, they also present a practical approach to the management and treatme

This text provides a succinct definition of all the terms used in Generalized Anxiety Disorder (GAD) including different diagnoses, classifications and treatments.