Search

Your search keyword '"Lutiis, M. A."' showing total 4 results
Start Over Author "Lutiis, M. A." Publisher country:ita
4 results on '"Lutiis, M. A."'

1. Impact of IL-18 on inflammation

Author

Tripodi, Domenico, Macauro, G, Anogeianaki, A, Castellani, M. L., Pandolfi, Franco, Felaco, P, Toniato, E, De Lutiis, M. A., Fulcheri, M., Tete, S., Galzio, R., Salini, V., Caraffa, A., Antinolfi, P., Frydas, I., Sabatino, G., Shaik Dasthagirisaheb, Y. B., Pandolfi, Franco (ORCID:0000-0001-8799-8173), Tripodi, Domenico, Macauro, G, Anogeianaki, A, Castellani, M. L., Pandolfi, Franco, Felaco, P, Toniato, E, De Lutiis, M. A., Fulcheri, M., Tete, S., Galzio, R., Salini, V., Caraffa, A., Antinolfi, P., Frydas, I., Sabatino, G., Shaik Dasthagirisaheb, Y. B., and Pandolfi, Franco (ORCID:0000-0001-8799-8173)

Abstract

IL-18 is produced by many cell types, such as Kupffer cells, keratinocytes, macrophages, dendritic cells, and activated T cells stimulated by LPS. It is an important regulator of both innate and acquired immune responses. IL-18 plays a central role in rheumatoid arthritis since the T cells and macrophages that invade the synovial. These finding support a role for IL-18 in inflammation, allergy and immune diseases.

Published
2011

2. VEGF, substance P and stress, new aspects: a revisited study.

Author

Castellani, M. L., Galzio, R. J., Felaco, P., Tripodi, D., Toniato, E., De Lutiis, M. A., Conti, F., Fulcheri, M., Conti, C., Theoharides, T. C., Caraffa, A., Antinolfi, P., Felaco, M., Tete, S., Pandolfi, Franco, Shaik Dasthagirisaheb, Y. B., Pandolfi, Franco (ORCID:0000-0001-8799-8173), Castellani, M. L., Galzio, R. J., Felaco, P., Tripodi, D., Toniato, E., De Lutiis, M. A., Conti, F., Fulcheri, M., Conti, C., Theoharides, T. C., Caraffa, A., Antinolfi, P., Felaco, M., Tete, S., Pandolfi, Franco, Shaik Dasthagirisaheb, Y. B., and Pandolfi, Franco (ORCID:0000-0001-8799-8173)

Abstract

Mast cells play an essential role in diverse physiological and pathological processes, such as atherosclerosis, malignancy, asthma, pulmonary fibrosis and arthritis, directly interact with bacteria, and appear to play a vital role in host defense against pathogens. Mast cells could be recruited in the inflammatory site, by MCP-1, RANTES and SCF, to selectively secrete proinflammatory molecules; these could include growth factors, histamine, which is mitogenic (H1) and an immunosuppressant (H2), neovascularization agents, such as heparin, IL-8, and VEGF, as well as proteases that could permit new blood vessel formation. Neurogenic inflammation involves vasodilation and plasma protein extravasation in response to neural stimulation. Upon stimulation, sensory neurons release Substance P and other neuropeptides and activate neurokinin-1 receptors leading to plasma protein extravasation from post-capillary venules. Substance P is a neuropeptide that is released from nerve endings in many tissues and plays an important role in immunological and inflammatory states, and it is also a mediator of tissue injury, asthma, arthritis, allergy and autoimmune diseases. SP-positive nerve fibers and mast cell contacts are increased by acute stress in mice leading to dermal mast cell degranulation. VEGF is produced by flammatory cells. IL-33 is the newest inflammatory member of the IL-1 cytokine family and we show here that SP can induce VEGF secretion from mast cells and IL-33 augments the effect of SP in VEGF transcription and translation protein.

Published
2010

3. IL-31 a Th2 cytokine involved in immunity and inflammation.

Author

Castellani, Ml, Felaco, P., Galzio, R. J., Tripodi, D., Toniato, E., De Lutiis, M. A., Fulcheri, M., Caraffa, A., Antinolfi, P., Tete, S., Felaco, M., Conti, F., Pandolfi, Franco, Theoharides, T. C., Shaiki Dathagirisaheb, Y. B., Pandolfi, Franco (ORCID:0000-0001-8799-8173), Castellani, Ml, Felaco, P., Galzio, R. J., Tripodi, D., Toniato, E., De Lutiis, M. A., Fulcheri, M., Caraffa, A., Antinolfi, P., Tete, S., Felaco, M., Conti, F., Pandolfi, Franco, Theoharides, T. C., Shaiki Dathagirisaheb, Y. B., and Pandolfi, Franco (ORCID:0000-0001-8799-8173)

Abstract

Cytokines are immunal regulatory proteins, however they also play a relevant role in inflammatory diseases. IL-31 is a newly discovered cytokine expressed primarily in TH2 cells, introduced by activated CD4+ T cells. IL-31 is capable of inducing chemokines and other cytokines in several inflammatory diseases via its surface receptor. This cytokine is also produced by mast cells and mast cell line, suggesting a role in allergic diseases. In this editorial we revisit the biological role of IL-31 in immunity and inflammation.

Published
2010

4. Vitamins and mast cells.

Author

Anogeianaki, A., Castellani, M. L., Tripodi, D., Toniato, E., De Lutiis, M. A., Conti, F., Felaco, P., Fulcheri, M., Theoharides, T. C., Galzio, R., Caraffa, A., Antinolfi, P., Cuccurullo, C., Ciampoli, C., Felaco, M., Cerulli, Giuliano Giorgio, Pandolfi, Franco, Sabatino, G., Neri, G., Shaik Dathagirisaheb, Y. B., Cerulli, Giuliano Giorgio (ORCID:0000-0003-4990-1902), Pandolfi, Franco (ORCID:0000-0001-8799-8173), Anogeianaki, A., Castellani, M. L., Tripodi, D., Toniato, E., De Lutiis, M. A., Conti, F., Felaco, P., Fulcheri, M., Theoharides, T. C., Galzio, R., Caraffa, A., Antinolfi, P., Cuccurullo, C., Ciampoli, C., Felaco, M., Cerulli, Giuliano Giorgio, Pandolfi, Franco, Sabatino, G., Neri, G., Shaik Dathagirisaheb, Y. B., Cerulli, Giuliano Giorgio (ORCID:0000-0003-4990-1902), and Pandolfi, Franco (ORCID:0000-0001-8799-8173)

Abstract

N/A

Published
2010

Catalog

Books, media, physical & digital resources
See catalog results